Michael D Gunn

Department of Neurosurgery and the Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Medical Sciences Research Building, Rm 181c, Box 3156, Durham, NC, 27710, USA.

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May 2019

Author Correction: Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors.

Nat Med 2019 Mar;25(3):529

Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, NC, USA.

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March 2019

Biased agonists of the chemokine receptor CXCR3 differentially control chemotaxis and inflammation.

Authors:

Jeffrey S Smith Lowell T Nicholson Jutamas Suwanpradid Rachel A Glenn Nicole M Knape Priya Alagesan Jaimee N Gundry Thomas S Wehrman Amber Reck Atwater Michael D Gunn Amanda S MacLeod Sudarshan Rajagopal

Sci Signal 2018 11 6;11(555). Epub 2018 Nov 6.

Department of Biochemistry, Duke University, Durham, NC 27710, USA.

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November 2018

Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors.

Nat Med 2018 09 13;24(9):1459-1468. Epub 2018 Aug 13.

Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, NC, USA.

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September 2018

Interleukin 1 receptor (IL-1R1) activation exacerbates toxin-induced acute kidney injury.

Authors:

Jamie R Privratsky Jiandong Zhang Xiaohan Lu Nathan Rudemiller Qingqing Wei Yen-Rei Yu Michael D Gunn Steven D Crowley

Am J Physiol Renal Physiol 2018 09 23;315(3):F682-F691. Epub 2018 May 23.

Department of Medicine, Duke University Medical Center , Durham, North Carolina.

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September 2018

Nanoparticle formulation improves doxorubicin efficacy by enhancing host antitumor immunity.

Authors:

Eric M Mastria Leon Y Cai Matthew J Kan Xinghai Li Jeffrey L Schaal Steven Fiering Michael D Gunn Mark W Dewhirst Smita K Nair Ashutosh Chilkoti

J Control Release 2018 01 13;269:364-373. Epub 2017 Nov 13.

Department of Biomedical Engineering, Duke University, Durham, NC, USA; Center for Biologically Inspired Materials and Materials Systems, Duke University, Durham, NC, USA. Electronic address:

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January 2018

The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells.

Authors:

Amy E Baek Yen-Rei A Yu Sisi He Suzanne E Wardell Ching-Yi Chang Sanghoon Kwon Ruchita V Pillai Hannah B McDowell J Will Thompson Laura G Dubois Patrick M Sullivan Jongsook K Kemper Michael D Gunn Donald P McDonnell Erik R Nelson

Nat Commun 2017 10 11;8(1):864. Epub 2017 Oct 11.

Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, 407S Goodwin Avenue (MC-114), Urbana, IL, 61801, USA.

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October 2017

C-C Motif Chemokine 5 Attenuates Angiotensin II-Dependent Kidney Injury by Limiting Renal Macrophage Infiltration.

Authors:

Nathan P Rudemiller Mehul B Patel Jian-Dong Zhang Alexander D Jeffs Norah S Karlovich Robert Griffiths Matthew J Kan Anne F Buckley Michael D Gunn Steven D Crowley

Am J Pathol 2016 11 15;186(11):2846-2856. Epub 2016 Sep 15.

Division of Nephrology, Department of Medicine, Duke University Medical Center, Durham, North Carolina; Durham VA Medical Center, Durham, North Carolina. Electronic address:

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November 2016

A Protocol for the Comprehensive Flow Cytometric Analysis of Immune Cells in Normal and Inflamed Murine Non-Lymphoid Tissues.

Authors:

Yen-Rei A Yu Emily G O'Koren Danielle F Hotten Matthew J Kan David Kopin Erik R Nelson Loretta Que Michael D Gunn

PLoS One 2016 3;11(3):e0150606. Epub 2016 Mar 3.

Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, North Carolina, United States of America.

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August 2016

Correction: Ozone Inhalation Promotes CX3CR1-Dependent Maturation of Resident Lung Macrophages That Limit Oxidative Stress and Inflammation.

Authors:

Robert M Tighe Zhuowei Li Erin N Potts Sarah Frush Ningshan Liu Michael D Gunn W Michael Foster Paul W Noble John W Hollingsworth

J Immunol 2016 Mar;196(5):2424

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March 2016

Flow Cytometric Analysis of Myeloid Cells in Human Blood, Bronchoalveolar Lavage, and Lung Tissues.

Authors:

Yen-Rei A Yu Danielle F Hotten Yuryi Malakhau Ellen Volker Andrew J Ghio Paul W Noble Monica Kraft John W Hollingsworth Michael D Gunn Robert M Tighe

Am J Respir Cell Mol Biol 2016 Jan;54(1):13-24

1 Department of Medicine, Duke University, Durham, North Carolina.

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January 2016

Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease.

Authors:

Matthew J Kan Jennifer E Lee Joan G Wilson Angela L Everhart Candice M Brown Andrew N Hoofnagle Marilyn Jansen Michael P Vitek Michael D Gunn Carol A Colton

J Neurosci 2015 Apr;35(15):5969-82

Department of Neurology, Duke University Medical Center, Durham, North Carolina 27710,

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April 2015

Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients.

Authors:

Duane A Mitchell Kristen A Batich Michael D Gunn Min-Nung Huang Luis Sanchez-Perez Smita K Nair Kendra L Congdon Elizabeth A Reap Gary E Archer Annick Desjardins Allan H Friedman Henry S Friedman James E Herndon April Coan Roger E McLendon David A Reardon James J Vredenburgh Darell D Bigner John H Sampson

Nature 2015 Mar 11;519(7543):366-9. Epub 2015 Mar 11.

1] Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina 27710, USA [2] Division of Neurosurgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA [3] Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA [4] Department of Immunology, Duke University Medical Center, Durham, North Carolina 27710, USA [5] Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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March 2015

S1P-Dependent trafficking of intracellular yersinia pestis through lymph nodes establishes Buboes and systemic infection.

Authors:

Ashley L St John W X Gladys Ang Min-Nung Huang Christian A Kunder Elizabeth W Chan Michael D Gunn Soman N Abraham

Immunity 2014 Sep;41(3):440-450

Program in Emerging Infectious Diseases, Duke-National University of Singapore, Singapore 169857, Singapore; Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA; Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA; Department of Immunology, Duke University Medical Center, Durham, NC 27710, USA.

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September 2014

Role of C-C motif ligand 2 and C-C motif receptor 2 in murine pulmonary graft-versus-host disease after lipopolysaccharide inhalations.

Authors:

Tereza Martinu Kymberly M Gowdy Julia L Nugent Jesse Sun Christine V Kinnier Margaret E Nelson Matthew A Lyes Francine L Kelly W Michael Foster Michael D Gunn Scott M Palmer

Am J Respir Cell Mol Biol 2014 Dec;51(6):810-21

1 Department of Medicine and.

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December 2014

Natural genetic variation of integrin alpha L (Itgal) modulates ischemic brain injury in stroke.

Authors:

Sehoon Keum Han Kyu Lee Pei-Lun Chu Matthew J Kan Min-Nung Huang Carol J Gallione Michael D Gunn Donald C Lo Douglas A Marchuk

PLoS Genet 2013 10;9(10):e1003807. Epub 2013 Oct 10.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America.

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March 2014

Identification of a tissue-specific, C/EBPβ-dependent pathway of differentiation for murine peritoneal macrophages.

Authors:

Derek W Cain Emily G O'Koren Matthew J Kan Mandy Womble Gregory D Sempowski Kristen Hopper Michael D Gunn Garnett Kelsoe

J Immunol 2013 Nov 27;191(9):4665-75. Epub 2013 Sep 27.

Department of Immunology, Duke University, Durham, NC 27710;

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November 2013

CCR2 deficiency, dysregulation of Notch signaling, and spontaneous pulmonary arterial hypertension.

Authors:

Yen-Rei A Yu Lan Mao Claude A Piantadosi Michael D Gunn

Am J Respir Cell Mol Biol 2013 May;48(5):647-54

Division of Pulmonary and Critical Care, Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.

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May 2013

A comparison of non-toxin vaccine adjuvants for their ability to enhance the immunogenicity of nasally-administered anthrax recombinant protective antigen.

Authors:

William M Gwinn Brandi T Johnson Shaun M Kirwan Ashley E Sobel Soman N Abraham Michael D Gunn Herman F Staats

Vaccine 2013 Mar 23;31(11):1480-9. Epub 2013 Jan 23.

Duke University Medical Center, Department of Pathology, Durham, NC 27710, USA.

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March 2013

NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis.

Authors:

Makoto Inoue Kristi L Williams Michael D Gunn Mari L Shinohara

Proc Natl Acad Sci U S A 2012 Jun 13;109(26):10480-5. Epub 2012 Jun 13.

Department of Immunology, and School of Nursing, Duke University Medical Center, Durham, NC 27710, USA.

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June 2012

Maximal adjuvant activity of nasally delivered IL-1α requires adjuvant-responsive CD11c(+) cells and does not correlate with adjuvant-induced in vivo cytokine production.

Authors:

Afton L Thompson Brandi T Johnson Gregory D Sempowski Michael D Gunn Baidong Hou Anthony L DeFranco Herman F Staats

J Immunol 2012 Mar 15;188(6):2834-46. Epub 2012 Feb 15.

Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA.

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March 2012

Ozone inhalation promotes CX3CR1-dependent maturation of resident lung macrophages that limit oxidative stress and inflammation.

Authors:

Robert M Tighe Zhuowei Li Erin N Potts Sarah Frush Ningshan Liu Michael D Gunn W Michael Foster Paul W Noble John W Hollingsworth

J Immunol 2011 Nov 19;187(9):4800-8. Epub 2011 Sep 19.

Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.

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November 2011

NUR who? An orphan transcription factor holds promise for monomaniacs.

Authors:

Derek W Cain Michael D Gunn

Nat Immunol 2011 Jul 19;12(8):727-9. Epub 2011 Jul 19.

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July 2011

Cowpox virus induces interleukin-10 both in vitro and in vivo.

Authors:

April H Spesock Brice E Barefoot Caroline A Ray Daniel J Kenan Michael D Gunn Elizabeth A Ramsburg David J Pickup

Virology 2011 Aug 11;417(1):87-97. Epub 2011 Jun 11.

Department of Molecular Genetics and Microbiology, Box 3020, Duke University Medical Center, Durham, NC 27710, USA.

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August 2011

Recruited exudative macrophages selectively produce CXCL10 after noninfectious lung injury.

Authors:

Robert M Tighe Jiurong Liang Ningshan Liu Yoosun Jung Dianhua Jiang Michael D Gunn Paul W Noble

Am J Respir Cell Mol Biol 2011 Oct 17;45(4):781-8. Epub 2011 Feb 17.

Department of Medicine, Duke University Medical Center, Durham, NC, USA.

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October 2011

Mast cells augment adaptive immunity by orchestrating dendritic cell trafficking through infected tissues.

Authors:

Christopher P Shelburne Hideki Nakano Ashley L St John Cheryl Chan James B McLachlan Michael D Gunn Herman F Staats Soman N Abraham

Cell Host Microbe 2009 Oct;6(4):331-42

Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA.

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October 2009

Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses.

Authors:

Hideki Nakano Kaifeng Lisa Lin Manabu Yanagita Chantal Charbonneau Donald N Cook Terutaka Kakiuchi Michael D Gunn

Nat Immunol 2009 Apr 1;10(4):394-402. Epub 2009 Mar 1.

Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.

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April 2009

Identification of recombinant antibodies against multiple distinct toll-like receptors by homolog mining a single immune scFv phage library.

Authors:

Yu-Hsun Chen Barbara D Lipes Daniel J Kenan Herman F Staats Michael D Gunn

J Immunol Methods 2009 Jan 17;340(2):144-53. Epub 2008 Nov 17.

Department of Immunology, Duke University Medical Center, Durham, North Carolina 27710, United States.

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January 2009

Mice that overexpress CC chemokine ligand 2 in their lungs show increased protective immunity to infection with Mycobacterium bovis bacille Calmette-Guérin.

Authors:

Olivia Schreiber Kathrin Steinwede Nadine Ding Mrigank Srivastava Regina Maus Florian Länger Jana Prokein Stefan Ehlers Tobias Welte Michael D Gunn Ulrich A Maus

J Infect Dis 2008 Oct;198(7):1044-54

Department of Pulmonary Medicine, Research Center Borstel, Germany.

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October 2008

Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs.

Authors:

Hidenobu Kanda Rebecca Newton Russell Klein Yuka Morita Michael D Gunn Steven D Rosen

Nat Immunol 2008 Apr 9;9(4):415-23. Epub 2008 Mar 9.

Department of Anatomy, Program in Immunology, Cardiovascular Research Institute, University of California San Francisco, San Francisco, California 94143, USA.

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April 2008

Lung-specific overexpression of CC chemokine ligand (CCL) 2 enhances the host defense to Streptococcus pneumoniae infection in mice: role of the CCL2-CCR2 axis.

Authors:

Christine Winter Katharina Taut Mrigank Srivastava Florian Länger Matthias Mack David E Briles James C Paton Regina Maus Tobias Welte Michael D Gunn Ulrich A Maus

J Immunol 2007 May;178(9):5828-38

Department of Pulmonary Medicine, Laboratory for Experimental Lung Research, Hannover School of Medicine, Hannover 30625, Germany.

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May 2007

Enhanced allergen-induced airway inflammation in paucity of lymph node T cell (plt) mutant mice.

Authors:

Dan Grinnan Sun-Sang Sung Joseph A Dougherty Amy Ryce Knowles Matthew B Allen Charles E Rose Hideki Nakano Michael D Gunn Shu Man Fu C Edward Rose

J Allergy Clin Immunol 2006 Dec 6;118(6):1234-41. Epub 2006 Oct 6.

Division of Pulmonary and Critical Care Medicine, University of Virginia School of Medicine, Charlottesville, VA 22901, USA.

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December 2006

TLR4 signaling attenuates ongoing allergic inflammation.

Authors:

John W Hollingsworth Gregory S Whitehead Kaifeng Lisa Lin Hideki Nakano Michael D Gunn David A Schwartz Donald N Cook

J Immunol 2006 May;176(10):5856-62

Division of Pulmonary, Allergy, and Critical Care Medicine, Duke University Medical Center, Durham, NC 27710, USA.

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May 2006

Permanent survival of fully MHC-mismatched islet allografts by targeting a single chemokine receptor pathway.

Authors:

Liqing Wang Rongxiang Han Iris Lee Aidan S Hancock Guoxiang Xiong Michael D Gunn Wayne W Hancock

J Immunol 2005 Nov;175(10):6311-8

Division of Transplantation Immunology, Department of Pathology and Laboratory Medicine, Joseph Stokes Jr. Research Institute and Biesecker Pediatric Liver Center, Philadelphia, PA 19104, USA.

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November 2005