Michael D Feldman

Michael D Feldman

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Michael D Feldman

Michael D Feldman

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Deep-learning approaches for Gleason grading of prostate biopsies.

Lancet Oncol 2020 Jan 8. Epub 2020 Jan 8.

Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.1016/S1470-2045(19)30793-4DOI Listing
January 2020

Clinical Implications of Carcinoma In Situ in Sinonasal Inverted Papilloma.

Otolaryngol Head Neck Surg 2019 Dec 22;161(6):1036-1042. Epub 2019 Oct 22.

Department of Otorhinolaryngology-Head & Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1177/0194599819883298DOI Listing
December 2019

Microbiome signatures in prostate cancer.

Carcinogenesis 2019 Jul;40(6):749-764

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1093/carcin/bgz008DOI Listing
July 2019

Computational staining of unlabelled tissue.

Nat Biomed Eng 2019 06;3(6):425-426

Center for Biomedical Image Computing and Analytics, Richards Medical Research Laboratories, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/s41551-019-0414-3DOI Listing
June 2019

Automated Comparison of Pathology Reports for On-the-job Assessment of Residents.

AMIA Jt Summits Transl Sci Proc 2019 6;2019:495-504. Epub 2019 May 6.

Perelman School of Medicine, University of Pennsylvania.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568070PMC
May 2019

Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 Diabetes.

Cell Metab 2019 03 31;29(3):769-783.e4. Epub 2019 Jan 31.

Department of Genetics and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436557PMC
March 2019

Sinonasal Undifferentiated Carcinoma: A 15-Year Single Institution Experience.

J Neurol Surg B Skull Base 2019 Feb 16;80(1):88-95. Epub 2018 Aug 16.

Department of Otorhinolaryngology - Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, United States.

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http://dx.doi.org/10.1055/s-0038-1668537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365239PMC
February 2019

Adenocarcinoma, Not Otherwise Specified, Arising in Accessory Lacrimal Gland: A Diagnostic Challenge.

Ocul Oncol Pathol 2018 Sep 12;4(2):67-72. Epub 2017 Aug 12.

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, New York, NY, USA.

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http://dx.doi.org/10.1159/000478730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167685PMC
September 2018

COX-2 mediates pro-tumorigenic effects of PKCε in prostate cancer.

Oncogene 2018 08 16;37(34):4735-4749. Epub 2018 May 16.

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1038/s41388-018-0318-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195867PMC
August 2018

Distinct Microbial Signatures Associated With Different Breast Cancer Types.

Front Microbiol 2018 15;9:951. Epub 2018 May 15.

Tumor Virology Program, Department of Otorhinolaryngology-Head and Neck Surgery and Microbiology, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

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http://dx.doi.org/10.3389/fmicb.2018.00951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962706PMC
May 2018

A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease.

N Engl J Med 2018 03;378(12):1096-1106

From the Regeneron Genetics Center (N.S.A.-H., A.H.L., C.S., S. McCarthy, C.O., J.S.P., S.B., N.G., S. Mukherjee, A.E.L., E.D.F., J.P., I.B.B., A.R.S., J.G.R., J.D.O., O.G., T.M.T., A.B., F.E.D.) and Regeneron Pharmaceuticals (X. Cheng, Y.X., P.S., Y.L., D.E., S.Y.K., B.Z., W.O., A.J.M., G.D.Y., J.G.), Tarrytown, NY; the University of Texas Southwestern Medical Center at Dallas, Dallas (J.K., S.S., H.H.H., J.C.C.); and Geisinger Health System, Danville (G.C.W., A.N.S., M.D.S., X. Chu, J.Z.L., U.L.M., D.J.C., C.D.S., T.M.), and Perelman School of Medicine, University of Pennsylvania, Philadelphia (M.D.F., A.S., S.M.D., D.J.R.) - both in Pennsylvania.

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http://dx.doi.org/10.1056/NEJMoa1712191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668033PMC
March 2018

Microbial Signatures Associated with Oropharyngeal and Oral Squamous Cell Carcinomas.

Sci Rep 2017 06 22;7(1):4036. Epub 2017 Jun 22.

Department of Otorhinolaryngology-Head and neck surgery, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, United States of America.

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http://dx.doi.org/10.1038/s41598-017-03466-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481414PMC
June 2017

The ovarian cancer oncobiome.

Oncotarget 2017 May;8(22):36225-36245

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, United States of America.

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http://dx.doi.org/10.18632/oncotarget.16717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482651PMC
May 2017

Validation of a Gene Expression Test for Mesothelioma Prognosis in Formalin-Fixed Paraffin-Embedded Tissues.

J Mol Diagn 2017 01 15;19(1):65-71. Epub 2016 Nov 15.

Thoracic Surgery Oncology Laboratory and the International Mesothelioma Program, Division of Thoracic Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2016.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225306PMC
January 2017

Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade.

Cell 2016 Dec;167(6):1540-1554.e12

Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.11.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385895PMC
December 2016

Sinonasal undifferentiated carcinoma as a third primary neoplasm: A case report and review of the literature.

Ear Nose Throat J 2015 Apr-May;94(4-5):178-82

Division of Facial Plastic and Reconstructive Surgery, Washington University, 1020 N. Mason Rd., Suite 205, St. Louis, MO 63141.

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November 2016

Systematic evaluation of multiple immune markers reveals prognostic factors in ovarian cancer.

Gynecol Oncol 2016 10 25;143(1):120-127. Epub 2016 Jul 25.

Ovarian Cancer Research Center, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Pathology & Laboratory Medicine, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2016.07.105DOI Listing
October 2016

Evaluating stability of histomorphometric features across scanner and staining variations: prostate cancer diagnosis from whole slide images.

J Med Imaging (Bellingham) 2016 Oct 24;3(4):047502. Epub 2016 Oct 24.

Case Western Reserve University , Department of Biomedical Engineering, 2071 Martin Luther King Jr. Drive, Cleveland, Ohio 44106, United States.

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http://dx.doi.org/10.1117/1.JMI.3.4.047502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076015PMC
October 2016

pAKT Expression and Response to Sorafenib in Differentiated Thyroid Cancer.

Horm Cancer 2016 06 18;7(3):188-95. Epub 2016 Mar 18.

Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/s12672-016-0253-6DOI Listing
June 2016

Olfactory Neuroblastoma: Fate of the Neck--A Long-term Multicenter Retrospective Study.

Otolaryngol Head Neck Surg 2016 Feb 15;154(2):383-9. Epub 2015 Dec 15.

Rhinology and Skull Base Research Group, Applied Medical Research Centre, St Vincent's Hospital, University of New South Wales, Sydney, Australia Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1177/0194599815620173DOI Listing
February 2016

Editorial Commentary: "All That Glitters Is Not Gold".

Arthroscopy 2016 Feb;32(2):348-9

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http://dx.doi.org/10.1016/j.arthro.2015.12.012DOI Listing
February 2016

Computer-extracted Features Can Distinguish Noncancerous Confounding Disease from Prostatic Adenocarcinoma at Multiparametric MR Imaging.

Radiology 2016 Jan 17;278(1):135-45. Epub 2015 Jul 17.

From the Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Geert Grooteplein 10, 6525 GA, Nijmegen, the Netherlands (G.J.S.L., T.K., C.H.v.d.K., J.O.B., H.J.H.); Departments of Pathology (R.E.) and Biomedical Engineering (A.M.), Case Western University Hospitals, Cleveland, Ohio; and Department of Pathology, University of Pennsylvania, Philadelphia, Pa (N.N.C.S., M.D.F.).

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http://dx.doi.org/10.1148/radiol.2015142856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699495PMC
January 2016

Progressive loss of anti-HER2 CD4 T-helper type 1 response in breast tumorigenesis and the potential for immune restoration.

Oncoimmunology 2015 Oct 1;4(10):e1022301. Epub 2015 Apr 1.

Department of Surgery; University Pennsylvania Perelman School of Medicine ; Philadelphia, PA USA ; Rena Rowen Breast Center; Hospital of the University of Pennsylvania ; Philadelphia, PA USA.

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http://dx.doi.org/10.1080/2162402X.2015.1022301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589053PMC
October 2015

Generation of Potent T-cell Immunotherapy for Cancer Using DAP12-Based, Multichain, Chimeric Immunoreceptors.

Cancer Immunol Res 2015 Jul 4;3(7):815-26. Epub 2015 May 4.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/2326-6066.CIR-15-0054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490943PMC
July 2015

The Ovarian Cancer Chemokine Landscape Is Conducive to Homing of Vaccine-Primed and CD3/CD28-Costimulated T Cells Prepared for Adoptive Therapy.

Clin Cancer Res 2015 Jun 23;21(12):2840-50. Epub 2015 Feb 23.

Ovarian Cancer Research Center, University of Pennsylvania, Philadelphia, Pennsylvania. Ludwig Cancer Research Center, University of Lausanne, Lausanne, Switzerland. Department of Oncology, University Hospital of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987088PMC
June 2015

Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer.

Nature 2015 Apr 9;520(7547):373-7. Epub 2015 Mar 9.

1] Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA [2] Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA [3] Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA [4] Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/nature14292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401634PMC
April 2015

An active learning approach for rapid characterization of endothelial cells in human tumors.

PLoS One 2014 6;9(3):e90495. Epub 2014 Mar 6.

Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090495PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946171PMC
January 2015

Computerized image analysis for identifying triple-negative breast cancers and differentiating them from other molecular subtypes of breast cancer on dynamic contrast-enhanced MR images: a feasibility study.

Radiology 2014 Jul 10;272(1):91-9. Epub 2014 Mar 10.

From the Department of Biomedical Engineering, Rutgers University, 599 Taylor Rd, Room 213, Piscataway, NJ 08854 (S.C.A.); Departments of Radiology (M.A.R., S.E., M.D.S.) and Pathology (M.D.F., P.Z., C.M.), University of Pennsylvania, Philadelphia, Pa; Department of Pathology and Anatomical Science, State University of New York at the University at Buffalo, Buffalo, NY (J.E.T.); and Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio (A.M.).

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http://dx.doi.org/10.1148/radiol.14121031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263619PMC
July 2014

The clinical presentation and outcome of urothelial atypia on biopsy of the bladder.

Urol Oncol 2014 Jul 9;32(5):645-7. Epub 2014 May 9.

Division of Urology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1016/j.urolonc.2014.01.007DOI Listing
July 2014

Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors.

Nat Med 2014 Jun 4;20(6):607-15. Epub 2014 May 4.

1] Ovarian Cancer Research Center, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA. [2].

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http://www.nature.com/articles/nm.3541
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http://dx.doi.org/10.1038/nm.3541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060245PMC
June 2014

Optical malignancy parameters for monitoring progression of breast cancer neoadjuvant chemotherapy.

Biomed Opt Express 2013 Jan 14;4(1):105-21. Epub 2012 Dec 14.

Dept. of Physics and Astronomy, University of Pennsylvania, 209 S. 33rd St., Philadelphia, PA 19104 USA.

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http://dx.doi.org/10.1364/BOE.4.000105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539198PMC
January 2013

Ectopic functioning adrenocortical oncocytic adenoma (oncocytoma) with myelolipoma causing virilization.

Case Rep Pathol 2012 10;2012:326418. Epub 2012 Oct 10.

Department of Pathology and Laboratory Medicine, The Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1155/2012/326418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474228PMC
October 2012

Spatially weighted mutual information (SWMI) for registration of digitally reconstructed ex vivo whole mount histology and in vivo prostate MRI.

Conf Proc IEEE Eng Med Biol Soc 2011 ;2011:6269-72

Department of Biomedical Engineering at Rutgers, State University of New Jersey, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1109/IEMBS.2011.6091547DOI Listing
August 2012

Supervised regularized canonical correlation analysis: integrating histologic and proteomic data for predicting biochemical failures.

Conf Proc IEEE Eng Med Biol Soc 2011 ;2011:6434-7

Department of Electrical and Computer Engineering, Rutgers University, Piscataway, New Jersey 08854, USA.

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http://dx.doi.org/10.1109/IEMBS.2011.6091588DOI Listing
August 2012

Fungal rhinosinusitis: a retrospective microbiologic and pathologic review of 400 patients at a single university medical center.

Int J Otolaryngol 2012 8;2012:684835. Epub 2012 Feb 8.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, 3400 Spruce Street, 6 Founders, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1155/2012/684835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299344PMC
August 2012

High-throughput biomarker segmentation on ovarian cancer tissue microarrays via hierarchical normalized cuts.

IEEE Trans Biomed Eng 2012 May 13;59(5):1240-52. Epub 2011 Dec 13.

Indian Institute of Technology Bombay, Powai, Mumbai, Maharashtra, India.

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http://dx.doi.org/10.1109/TBME.2011.2179546DOI Listing
May 2012

Accumulation of intrahepatic islet amyloid in a nonhuman primate transplant model.

Endocrinology 2012 Apr 21;153(4):1673-83. Epub 2012 Feb 21.

Division of Transplantation, Department of Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104-5160, USA.

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http://dx.doi.org/10.1210/en.2011-1560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320262PMC
April 2012

Determining histology-MRI slice correspondences for defining MRI-based disease signatures of prostate cancer.

Comput Med Imaging Graph 2011 Oct-Dec;35(7-8):568-78. Epub 2011 Jan 21.

Department of Biomedical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/j.compmedimag.2010.12.003DOI Listing
January 2012

Ras-related protein 1 and the insulin-like growth factor type I receptor are associated with risk of progression in patients diagnosed with carcinoma in situ.

Breast Cancer Res Treat 2011 Sep 26;129(2):361-72. Epub 2010 Oct 26.

The Division of Endocrine and Oncologic Surgery, Department of Surgery, School of Medicine, University of Pennsylvania, 313 Stemmler Hall, 37th and Hamilton Walk, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s10549-010-1227-yDOI Listing
September 2011

Rapid In-situ hybridization for dematiaceous fungi using a broad-spectrum oligonucleotide DNA probe.

Diagn Mol Pathol 2011 Sep;20(3):180-3

Departments of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, USA.

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http://dx.doi.org/10.1097/PDM.0b013e31820e9c82DOI Listing
September 2011

In situ hybridization for specific fungal organisms in acute invasive fungal rhinosinusitis.

Am J Clin Pathol 2011 Feb;135(2):190-9

Dept of Pathology, University of Pennsylvania Medical Center, Philadelphia, USA.

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http://dx.doi.org/10.1309/AJCPQLYZBDF30HTMDOI Listing
February 2011

APOBEC3 proteins expressed in mammary epithelial cells are packaged into retroviruses and can restrict transmission of milk-borne virions.

Cell Host Microbe 2010 Dec;8(6):534-43

Department of Microbiology and Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.chom.2010.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023938PMC
December 2010

Downregulation of Rap1GAP in human tumor cells alters cell/matrix and cell/cell adhesion.

Mol Cell Biol 2010 Jul 3;30(13):3262-74. Epub 2010 May 3.

Department of Pharmacology, University of Pennsylvania School of Medicine, 421 Curie Blvd., BRB II/III, Philadelphia, PA 19104-6061, USA.

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http://dx.doi.org/10.1128/MCB.01345-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897574PMC
July 2010

Hierarchical normalized cuts: unsupervised segmentation of vascular biomarkers from ovarian cancer tissue microarrays.

Med Image Comput Comput Assist Interv 2009 ;12(Pt 1):230-8

Dept of Computer Science & Engineering, Indian Institute of Technology, Bombay.

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http://dx.doi.org/10.1007/978-3-642-04268-3_29DOI Listing
June 2010

HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.

J Clin Invest 2010 May 12;120(5):1535-50. Epub 2010 Apr 12.

Department of Pathology, Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1172/JCI39534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860938PMC
May 2010

Computerized image-based detection and grading of lymphocytic infiltration in HER2+ breast cancer histopathology.

IEEE Trans Biomed Eng 2010 Mar 30;57(3):642-53. Epub 2009 Oct 30.

Department of Biomedical Engineering, Rutgers University, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1109/TBME.2009.2035305DOI Listing
March 2010

In situ detection of aspergillus 18s ribosomal RNA Sequences using a terminally biotinylated locked nucleic acid (LNA) probe.

Diagn Mol Pathol 2009 Dec;18(4):239-42

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1097/PDM.0b013e3181952584DOI Listing
December 2009

Loss of Rap1GAP in papillary thyroid cancer.

J Clin Endocrinol Metab 2009 Mar 9;94(3):1026-32. Epub 2008 Dec 9.

Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1210/jc.2008-1042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681278PMC
March 2009

Embryonal and alveolar rhabdomyosarcoma of parameningeal sites in adults: a report of 13 cases.

Int J Surg Pathol 2009 Feb 22;17(1):22-30. Epub 2008 Oct 22.

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://journals.sagepub.com/doi/10.1177/1066896908325876
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http://dx.doi.org/10.1177/1066896908325876DOI Listing
February 2009

Activated STAT3 is a mediator and biomarker of VEGF endothelial activation.

Cancer Biol Ther 2008 Dec 11;7(12):1994-2003. Epub 2008 Dec 11.

Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932444PMC
http://dx.doi.org/10.4161/cbt.7.12.6967DOI Listing
December 2008

Validation and toxicity of PI3K/Akt pathway inhibition by HIV protease inhibitors in humans.

Cancer Biol Ther 2008 May 14;7(5):628-35. Epub 2008 May 14.

Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.4161/cbt.7.5.5728DOI Listing
May 2008

Beyond morphology: whole slide imaging, computer-aided detection, and other techniques.

Arch Pathol Lab Med 2008 May;132(5):758-63

Division of Surgical Pathology, University of Pennsylvania Health System, 6 Founders, 3400 Spruce St, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1043/1543-2165(2008)132[758:BMWSIC]2.0.CO;2DOI Listing
May 2008

Antitumor effect of the angiogenesis inhibitor bevacizumab is dependent on susceptibility of tumors to hypoxia-induced apoptosis.

Biochem Pharmacol 2008 Feb 11;75(3):627-38. Epub 2007 Oct 11.

Abramson Cancer Center, University of Pennsylvania, 1020 BRB II/III, 421 Curie Blvd., Philadelphia, PA 19104, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000629520700663
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http://dx.doi.org/10.1016/j.bcp.2007.09.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732335PMC
February 2008

High throughput analysis of breast cancer specimens on the grid.

Med Image Comput Comput Assist Interv 2007 ;10(Pt 1):617-25

Dept. of Electrical and Computer Eng., Rutgers Univ., Piscataway, NJ 08544, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366434PMC
http://dx.doi.org/10.1007/978-3-540-75757-3_75DOI Listing
January 2008

Dose-dependent effects of topical tobramycin in an animal model of Pseudomonas sinusitis.

Am J Rhinol 2007 Jul-Aug;21(4):423-7

Department of Otorhinolaryngology, Division of Rhinology, University of Pennsylvania, Philadelphia 19104, USA.

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http://dx.doi.org/10.2500/ajr.2007.21.3046DOI Listing
November 2007

Downregulation of Rap1GAP contributes to Ras transformation.

Mol Cell Biol 2007 Oct 23;27(19):6647-58. Epub 2007 Jul 23.

Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6061, USA.

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http://dx.doi.org/10.1128/MCB.00155-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099240PMC
October 2007