Publications by authors named "Michael Costigan"

56Publications

Cytotoxic Immunity in Peripheral Nerve Injury and Pain.

Front Neurosci 2020 21;14:142. Epub 2020 Feb 21.

Department of Brain and Cognitive Sciences, College of Natural Sciences, Seoul National University, Seoul, South Korea.

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February 2020

Human induced pluripotent stem cell-derived GABAergic interneuron transplants attenuate neuropathic pain.

Pain 2020 02;161(2):379-387

The Dr. John and Anne Chong Laboratory for Functional Genomics, Charles Perkins Centre and School of Life & Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.

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February 2020

The Genetics of Neuropathic Pain from Model Organisms to Clinical Application.

Neuron 2019 11;104(4):637-653

Neural Injury Group, Nuffield Department of Clinical Neuroscience, John Radcliffe Hospital, University of Oxford, Oxford, UK. Electronic address:

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November 2019

Reading and writing: the evolution of molecular pain genetics.

Pain 2019 10;160(10):2177-2185

Anesthesia Department, Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.

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October 2019

Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury.

Cell 2019 02 31;176(4):716-728.e18. Epub 2019 Jan 31.

Dental Research Institute and Department of Neurobiology and Physiology, School of Dentistry, Seoul National University, Seoul 03080, Republic of Korea; Department of Brain and Cognitive Sciences, College of Natural Sciences, Seoul National University, Seoul 08826, Republic of Korea. Electronic address:

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February 2019

Diltiazem Promotes Regenerative Axon Growth.

Mol Neurobiol 2019 Jun 19;56(6):3948-3957. Epub 2018 Sep 19.

F.M. Kirby Neurobiology Center, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA.

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June 2019

Up-Down Reader: An Open Source Program for Efficiently Processing 50% von Frey Thresholds.

Front Pharmacol 2018 1;9:433. Epub 2018 May 1.

Kirby Neurobiology Center, Boston Children's Hospital and Department of Neurobiology, Harvard Medical School, Boston, MA, United States.

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May 2018

Enhanced Neuronal Regeneration in the CAST/Ei Mouse Strain Is Linked to Expression of Differentiation Markers after Injury.

Cell Rep 2017 08;20(5):1136-1147

Department of Molecular, Cellular, and Developmental Biology, Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, CA 93106, USA. Electronic address:

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August 2017

Time-Resolved Fast Mammalian Behavior Reveals the Complexity of Protective Pain Responses.

Cell Rep 2017 07;20(1):89-98

Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA; FM Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA 02115, USA. Electronic address:

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July 2017

Combining Human and Rodent Genetics to Identify New Analgesics.

Neurosci Bull 2018 Feb 1;34(1):143-155. Epub 2017 Jul 1.

Kirby Neurobiology Center, Boston Children's Hospital and Department of Neurobiology, Harvard Medical School, Boston, MA, 02115, USA.

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February 2018

CNS repair and axon regeneration: Using genetic variation to determine mechanisms.

Exp Neurol 2017 Jan 6;287(Pt 3):409-422. Epub 2016 May 6.

FM Kirby Neurobiology Center and Anesthesia Department, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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January 2017

A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program.

Neuron 2016 Mar 18;89(5):956-70. Epub 2016 Feb 18.

Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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March 2016

Transcriptomic Approaches to Neural Repair.

J Neurosci 2015 Oct;35(41):13860-7

Department of Neurosciences, University of California, San Diego, La Jolla, California 92093, Veterans Affairs Medical Center, San Diego, California 92161.

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October 2015

Post-stroke pain hypersensitivity induced by experimental thalamic hemorrhage in rats is region-specific and demonstrates limited efficacy of gabapentin.

Neurosci Bull 2014 Dec 5;30(6):887-902. Epub 2014 Nov 5.

Institute for Biomedical Sciences of Pain, Tangdu Hospital, The Fourth Military Medical University, Xi'an, 710038, China.

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December 2014

Heritability of nociception IV: neuropathic pain assays are genetically distinct across methods of peripheral nerve injury.

Pain 2014 May 24;155(5):868-880. Epub 2013 Sep 24.

Department of Anesthesiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, Boston, MA, USA Department of Neurology, Boston Children's Hospital, Boston, MA, USA.

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May 2014

High energy diets-induced metabolic and prediabetic painful polyneuropathy in rats.

PLoS One 2013 25;8(2):e57427. Epub 2013 Feb 25.

Institute for Biomedical Sciences of Pain and Institute for Functional Brain Disorders, Tangdu Hospital, The Fourth Military Medical University, Xi'an, P. R. China.

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January 2014

Pain's peptide signature.

Authors:
Michael Costigan

Pain 2012 Mar 20;153(3):509-510. Epub 2012 Jan 20.

F.M. Kirby Neurobiology Center, Children's Hospital Boston, Harvard Medical School, 3 Blackfan Circle, CLS 12255, Boston, MA 02115, USA.

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March 2012

Analgesia by inhibiting tetrahydrobiopterin synthesis.

Curr Opin Pharmacol 2012 Feb 15;12(1):92-9. Epub 2011 Dec 15.

FM Kirby Neurobiology Center, Children's Hospital Boston, and Department of Neurobiology, Harvard Medical School, 3 Blackfan Circle, CLS 12260, Boston, MA 02115, USA.

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February 2012

Accelerating axonal growth promotes motor recovery after peripheral nerve injury in mice.

J Clin Invest 2011 Nov 3;121(11):4332-47. Epub 2011 Oct 3.

Program in Neurobiology and F.M. Kirby Neurobiology Center, Children’s Hospital Boston, and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA.

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November 2011

TrpA1 regulates thermal nociception in Drosophila.

PLoS One 2011 31;6(8):e24343. Epub 2011 Aug 31.

Neuroscience Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia.

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January 2012

GCH1, BH4 and pain.

Curr Pharm Biotechnol 2011 Oct;12(10):1728-41

FM Kirby Neurobiology Center, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.

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October 2011

T-cell infiltration and signaling in the adult dorsal spinal cord is a major contributor to neuropathic pain-like hypersensitivity.

J Neurosci 2009 Nov;29(46):14415-22

UCL Department of Neuroscience, Physiology & Pharmacology and UCL Department of Biochemistry, University College London, London WC1 EBT, United Kingdom.

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November 2009

Neuropathic pain: a maladaptive response of the nervous system to damage.

Annu Rev Neurosci 2009 ;32:1-32

Neural Plasticity Research Group, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02129, USA.

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October 2009

COX2 in CNS neural cells mediates mechanical inflammatory pain hypersensitivity in mice.

J Clin Invest 2009 Feb 5;119(2):287-94. Epub 2009 Jan 5.

Neural Plasticity Research Group, Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02129, USA.

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February 2009

Ro5-4864 promotes neonatal motor neuron survival and nerve regeneration in adult rats.

Eur J Neurosci 2008 Feb;27(4):937-46

Neural Plasticity Research Group, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.

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February 2008

GDNF selectively promotes regeneration of injury-primed sensory neurons in the lesioned spinal cord.

Mol Cell Neurosci 2007 Oct 24;36(2):185-94. Epub 2007 Jul 24.

Neural Plasticity Research Group, Massachusetts General Hospital and Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA.

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October 2007

Complement induction in spinal cord microglia results in anaphylatoxin C5a-mediated pain hypersensitivity.

J Neurosci 2007 Aug;27(32):8699-708

Neural Plasticity Research Group, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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August 2007

The voltage-gated sodium channel Na(v)1.9 is an effector of peripheral inflammatory pain hypersensitivity.

J Neurosci 2006 Dec;26(50):12852-60

Neural Plasticity Research Group, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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December 2006

Spinal microglia and neuropathic pain in young rats.

Pain 2007 Apr 15;128(3):215-224. Epub 2006 Nov 15.

Department of Anatomy and Developmental Biology, University College London, London WC1E 6BT, UK The University of Toronto Centre for the Study of Pain, Toronto, Ontario, Canada Neural Plasticity Research Group, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.

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April 2007

High basal expression and injury-induced down regulation of two regulator of G-protein signaling transcripts, RGS3 and RGS4 in primary sensory neurons.

Mol Cell Neurosci 2003 Sep;24(1):106-16

Neural Plasticity Research Group, Department of Anesthesia & Critical Care, Massachusetts General Hospital & Harvard Medical School, 13th Street, Building 149 (#4309), Charlestown, MA 02129, USA.

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September 2003

Exploiting microarrays to reveal differential gene expression in the nervous system.

Genome Biol 2003 29;4(2):105. Epub 2003 Jan 29.

Neural Plasticity Research Group, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.

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March 2003

Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury.

BMC Neurosci 2002 Oct 25;3:16. Epub 2002 Oct 25.

Neural Plasticity Research Group, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.

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October 2002

No DREAM, No pain. Closing the spinal gate.

Cell 2002 Feb;108(3):297-300

Neural Plasticity Research Group, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Massachusetts General Hospital-East, Charlestown, MA 02129, USA.

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February 2002