Michael Cho

Michael Cho

UNVERIFIED PROFILE

Are you Michael Cho?   Register this Author

Register author
Michael Cho

Michael Cho

Publications by authors named "Michael Cho"

Are you Michael Cho?   Register this Author

100Publications

3193Reads

16Profile Views

Turning subtypes into disease axes to improve prediction of COPD progression.

Thorax 2019 Sep 12;74(9):906-909. Epub 2019 Jun 12.

Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, United States

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/thoraxjnl-2018-213005DOI Listing
September 2019

Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis.

Authors:
Camille Moore Rachel Z Blumhagen Ivana V Yang Avram Walts Julie Powers Tarik Walker Makenna Bishop Pamela Russell Brian Vestal Jonathan Cardwell Cheryl R Markin Susan K Mathai Marvin I Schwarz Mark P Steele Joyce Lee Kevin K Brown James E Loyd James D Crapo Edwin K Silverman Michael H Cho Judith A James Joel M Guthridge Joy D Cogan Jonathan A Kropski Jeffrey J Swigris Carol Bair Dong Soon Kim Wonjun Ji Hocheol Kim Jin Woo Song Lisa A Maier Karin A Pacheco Nikhil Hirani Azin S Poon Feng Li R Gisli Jenkins Rebecca Braybrooke Gauri Saini Toby M Maher Philip L Molyneaux Peter Saunders Yingze Zhang Kevin F Gibson Daniel J Kass Mauricio Rojas John Sembrat Paul J Wolters Harold R Collard John S Sundy Thomas O'Riordan Mary E Strek Imre Noth Shwu-Fan Ma Mary K Porteous Maryl E Kreider Namrata B Patel Yoshikazu Inoue Masaki Hirose Toru Arai Shinobu Akagawa Oliver Eickelberg Isis Enlil Fernandez Jürgen Behr Nesrin Mogulkoc Tamera J Corte Ian Glaspole Sara Tomassetti Claudia Ravaglia Venerino Poletti Bruno Crestani Raphael Borie Caroline Kannengiesser Helen Parfrey Christine Fiddler Doris Rassl Maria Molina-Molina Carlos Machahua Ana Montes Worboys Gunnar Gudmundsson Helgi J Isaksson David J Lederer Anna J Podolanczuk Sydney B Montesi Elisabeth Bendstrup Vivi Danchel Moises Selman Annie Pardo Michael T Henry Michael P Keane Peter Doran Martina Vašáková Martina Sterclova Christopher J Ryerson Pearce G Wilcox Tsukasa Okamoto Haruhiko Furusawa Yasunari Miyazaki Geoffrey Laurent Svetlana Baltic Cecilia Prele Yuben Moodley Barry S Shea Ken Ohta Maho Suzukawa Osamu Narumoto Steven D Nathan Drew C Venuto Merte L Woldehanna Nurdan Kokturk Joao A de Andrade Tracy Luckhardt Tejaswini Kulkarni Francesco Bonella Seamus C Donnelly Aoife McElroy Michelle E Armstong Alvaro Aranda Roberto G Carbone Francesco Puppo Kenneth B Beckman Deborah A Nickerson Tasha E Fingerlin David A Schwartz

Am J Respir Crit Care Med 2019 Jul;200(2):199-208

1 National Jewish Health, Denver, Colorado.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.201810-1891OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635791PMC
July 2019

DSP variants may be associated with longitudinal change in quantitative emphysema.

Respir Res 2019 Jul 19;20(1):160. Epub 2019 Jul 19.

Department of Epidemiology, Johns Hopkins School of Public Health, 615 N. Wolfe Street, Baltimore, MD, 21205, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12931-019-1097-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642569PMC
July 2019

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Authors:
Nick Shrine Anna L Guyatt A Mesut Erzurumluoglu Victoria E Jackson Brian D Hobbs Carl A Melbourne Chiara Batini Katherine A Fawcett Kijoung Song Phuwanat Sakornsakolpat Xingnan Li Ruth Boxall Nicola F Reeve Ma'en Obeidat Jing Hua Zhao Matthias Wielscher Stefan Weiss Katherine A Kentistou James P Cook Benjamin B Sun Jian Zhou Jennie Hui Stefan Karrasch Medea Imboden Sarah E Harris Jonathan Marten Stefan Enroth Shona M Kerr Ida Surakka Veronique Vitart Terho Lehtimäki Richard J Allen Per S Bakke Terri H Beaty Eugene R Bleecker Yohan Bossé Corry-Anke Brandsma Zhengming Chen James D Crapo John Danesh Dawn L DeMeo Frank Dudbridge Ralf Ewert Christian Gieger Amund Gulsvik Anna L Hansell Ke Hao Joshua D Hoffman John E Hokanson Georg Homuth Peter K Joshi Philippe Joubert Claudia Langenberg Xuan Li Liming Li Kuang Lin Lars Lind Nicholas Locantore Jian'an Luan Anubha Mahajan Joseph C Maranville Alison Murray David C Nickle Richard Packer Margaret M Parker Megan L Paynton David J Porteous Dmitry Prokopenko Dandi Qiao Rajesh Rawal Heiko Runz Ian Sayers Don D Sin Blair H Smith María Soler Artigas David Sparrow Ruth Tal-Singer Paul R H J Timmers Maarten Van den Berge John C Whittaker Prescott G Woodruff Laura M Yerges-Armstrong Olga G Troyanskaya Olli T Raitakari Mika Kähönen Ozren Polašek Ulf Gyllensten Igor Rudan Ian J Deary Nicole M Probst-Hensch Holger Schulz Alan L James James F Wilson Beate Stubbe Eleftheria Zeggini Marjo-Riitta Jarvelin Nick Wareham Edwin K Silverman Caroline Hayward Andrew P Morris Adam S Butterworth Robert A Scott Robin G Walters Deborah A Meyers Michael H Cho David P Strachan Ian P Hall Martin D Tobin Louise V Wain

Nat Genet 2019 Jun;51(6):1067

Department of Health Sciences, University of Leicester, Leicester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-019-0438-3DOI Listing
June 2019

Diffuse Idiopathic Skeletal Hyperostosis in Smokers and Restrictive Spirometry Pattern: An Analysis of the COPDGene Cohort.

J Rheumatol 2019 May 1. Epub 2019 May 1.

From the University Medical Center Utrecht and Utrecht University, Department of Radiology and Nuclear Medicine, and Department of Orthopedics, Utrecht, the Netherlands; National Jewish Health, Department of Radiology, and divisions of Oncology, Pulmonary, Critical Care, Sleep Medicine, and Rheumatology, Denver, Colorado; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts; Division of Pulmonary, Allergy, and Critical Care Medicine, and Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama, USA; London School of Hygiene and Tropical Medicine, London, UK. This work was supported by the US National Heart, Lung, and Blood Institute (award number U01 HL089897, award number U01 HL089856). Dr. E.K. Silverman has received grant and travel support from GlaxoSmithKline. S.F. Oudkerk, MD, PhD, University Medical Center Utrecht and Utrecht University, Department of Radiology and Nuclear Medicine; F.A. Mohamed Hoesein, MD, PhD, University Medical Center Utrecht and Utrecht University, Department of Radiology and Nuclear Medicine; F.C. Öner, MD, PhD, University Medical Center Utrecht and Utrecht University, Department of Orthopedics; J.J. Verlaan, MD, PhD, University Medical Center Utrecht and Utrecht University, Department of Orthopedics; P.A. de Jong, MD, PhD, University Medical Center Utrecht and Utrecht University, Department of Radiology and Nuclear Medicine; J.S. Kuperus, MD, PhD, University Medical Center Utrecht and Utrecht University, Department of Orthopedics; M. Cho, MD, MPH, Channing Division of Network Medicine, Brigham and Women's Hospital; M.L. McDonald, MSc, PhD, Division of Pulmonary, Allergy and Critical Care Medicine, and Department of Genetics, University of Alabama at Birmingham; D.A. Lynch, MB, National Jewish Health, Department of Radiology, Division of Oncology, Cancer Center; E.K. Silverman, MD, PhD, Channing Division of Network Medicine, Brigham and Women's Hospital; J.D. Crapo, MD, National Jewish Health, divisions of Pulmonary, Critical Care, and Sleep Medicine; B.J. Make, MD, National Jewish Health, divisions of Pulmonary, Critical Care, and Sleep Medicine; K.E. Lowe, MSc, National Jewish Health, divisions of Pulmonary, Critical Care, and Sleep Medicine, and London School of Hygiene and Tropical Medicine; E.A. Regan, MD, PhD, National Jewish Health, Division of Rheumatology. Address correspondence to Dr. P.A. de Jong, Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Room E01.132, 3508 GA Utrecht, the Netherlands. E-mail: Accepted for publication April 6, 2019.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3899/jrheum.181357DOI Listing
May 2019

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Authors:
Nick Shrine Anna L Guyatt A Mesut Erzurumluoglu Victoria E Jackson Brian D Hobbs Carl A Melbourne Chiara Batini Katherine A Fawcett Kijoung Song Phuwanat Sakornsakolpat Xingnan Li Ruth Boxall Nicola F Reeve Ma'en Obeidat Jing Hua Zhao Matthias Wielscher Stefan Weiss Katherine A Kentistou James P Cook Benjamin B Sun Jian Zhou Jennie Hui Stefan Karrasch Medea Imboden Sarah E Harris Jonathan Marten Stefan Enroth Shona M Kerr Ida Surakka Veronique Vitart Terho Lehtimäki Richard J Allen Per S Bakke Terri H Beaty Eugene R Bleecker Yohan Bossé Corry-Anke Brandsma Zhengming Chen James D Crapo John Danesh Dawn L DeMeo Frank Dudbridge Ralf Ewert Christian Gieger Amund Gulsvik Anna L Hansell Ke Hao Joshua D Hoffman John E Hokanson Georg Homuth Peter K Joshi Philippe Joubert Claudia Langenberg Xuan Li Liming Li Kuang Lin Lars Lind Nicholas Locantore Jian'an Luan Anubha Mahajan Joseph C Maranville Alison Murray David C Nickle Richard Packer Margaret M Parker Megan L Paynton David J Porteous Dmitry Prokopenko Dandi Qiao Rajesh Rawal Heiko Runz Ian Sayers Don D Sin Blair H Smith María Soler Artigas David Sparrow Ruth Tal-Singer Paul R H J Timmers Maarten Van den Berge John C Whittaker Prescott G Woodruff Laura M Yerges-Armstrong Olga G Troyanskaya Olli T Raitakari Mika Kähönen Ozren Polašek Ulf Gyllensten Igor Rudan Ian J Deary Nicole M Probst-Hensch Holger Schulz Alan L James James F Wilson Beate Stubbe Eleftheria Zeggini Marjo-Riitta Jarvelin Nick Wareham Edwin K Silverman Caroline Hayward Andrew P Morris Adam S Butterworth Robert A Scott Robin G Walters Deborah A Meyers Michael H Cho David P Strachan Ian P Hall Martin D Tobin Louise V Wain

Nat Genet 2019 03 25;51(3):481-493. Epub 2019 Feb 25.

Department of Health Sciences, University of Leicester, Leicester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-018-0321-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397078PMC
March 2019

Cholesterol-dependent Modulation of Stem Cell Biomechanics: Application to Adipogenesis.

J Biomech Eng 2019 Mar 22. Epub 2019 Mar 22.

Department of Bioengineering, University of Texas at Arlington, Arlington, TX 76019.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4043253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528686PMC
March 2019

Astrocyte Viability and Functionality in Spatially Confined Microcavitation Zone.

ACS Appl Mater Interfaces 2019 Feb 25;11(5):4889-4899. Epub 2019 Jan 25.

Department of Bioengineering , University of Texas at Arlington , Arlington , Texas 76019 , United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acsami.8b21410DOI Listing
February 2019

Childhood asthma is associated with COPD and known asthma variants in COPDGene: a genome-wide association study.

Respir Res 2018 Oct 29;19(1):209. Epub 2018 Oct 29.

Channing Division of Network Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA, 02115, USA.

View Article

Download full-text PDF

Source
https://respiratory-research.biomedcentral.com/articles/10.1
Publisher Site
http://dx.doi.org/10.1186/s12931-018-0890-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206739PMC
October 2018

Cell Fragmentation and Permeabilization by a 1 ns Pulse Driven Triple-Point Electrode.

Biomed Res Int 2018 18;2018:4072983. Epub 2018 Mar 18.

Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2018/4072983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878903PMC
September 2018

Dissecting respiratory disease heterogeneity through the genetics of diffusing capacity.

Eur Respir J 2018 09 15;52(3). Epub 2018 Sep 15.

Channing Division of Network Medicine and Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://erj.ersjournals.com/lookup/doi/10.1183/13993003.01468
Publisher Site
http://dx.doi.org/10.1183/13993003.01468-2018DOI Listing
September 2018

¡HOLA! The Influence of Being Hispanic on Lung Ancestry.

Am J Respir Crit Care Med 2018 07;198(2):148-149

1 Channing Division of Network Medicine and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.201802-0306EDDOI Listing
July 2018

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.

Authors:
Annah B Wyss Tamar Sofer Mi Kyeong Lee Natalie Terzikhan Jennifer N Nguyen Lies Lahousse Jeanne C Latourelle Albert Vernon Smith Traci M Bartz Mary F Feitosa Wei Gao Tarunveer S Ahluwalia Wenbo Tang Christopher Oldmeadow Qing Duan Kim de Jong Mary K Wojczynski Xin-Qun Wang Raymond Noordam Fernando Pires Hartwig Victoria E Jackson Tianyuan Wang Ma'en Obeidat Brian D Hobbs Tianxiao Huan Hongsheng Gui Margaret M Parker Donglei Hu Lauren S Mogil Gleb Kichaev Jianping Jin Mariaelisa Graff Tamara B Harris Ravi Kalhan Susan R Heckbert Lavinia Paternoster Kristin M Burkart Yongmei Liu Elizabeth G Holliday James G Wilson Judith M Vonk Jason L Sanders R Graham Barr Renée de Mutsert Ana Maria Baptista Menezes Hieab H H Adams Maarten van den Berge Roby Joehanes Albert M Levin Jennifer Liberto Lenore J Launer Alanna C Morrison Colleen M Sitlani Juan C Celedón Stephen B Kritchevsky Rodney J Scott Kaare Christensen Jerome I Rotter Tobias N Bonten Fernando César Wehrmeister Yohan Bossé Shujie Xiao Sam Oh Nora Franceschini Jennifer A Brody Robert C Kaplan Kurt Lohman Mark McEvoy Michael A Province Frits R Rosendaal Kent D Taylor David C Nickle L Keoki Williams Esteban G Burchard Heather E Wheeler Don D Sin Vilmundur Gudnason Kari E North Myriam Fornage Bruce M Psaty Richard H Myers George O'Connor Torben Hansen Cathy C Laurie Patricia A Cassano Joohon Sung Woo Jin Kim John R Attia Leslie Lange H Marike Boezen Bharat Thyagarajan Stephen S Rich Dennis O Mook-Kanamori Bernardo Lessa Horta André G Uitterlinden Hae Kyung Im Michael H Cho Guy G Brusselle Sina A Gharib Josée Dupuis Ani Manichaikul Stephanie J London

Nat Commun 2018 07 30;9(1):2976. Epub 2018 Jul 30.

Epidemiology Branch National Institute of Environmental Health Sciences, National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, NC, 27709, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-018-05369-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065313PMC
July 2018

Adrenal insufficiency and ICS: genetics takes a breath.

Lancet Respir Med 2018 06 15;6(6):407-408. Epub 2018 Mar 15.

Brigham and Women's Hospital, Department of Medicine, Channing Division of Network Medicine, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-2600(18)30101-2DOI Listing
June 2018

Genome-wide assessment of gene-by-smoking interactions in COPD.

Sci Rep 2018 06 18;8(1):9319. Epub 2018 Jun 18.

Department of public health sciences, Seoul national university, Seoul, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-27463-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006158PMC
June 2018

Genotype imputation performance of three reference panels using African ancestry individuals.

Hum Genet 2018 Apr 10;137(4):281-292. Epub 2018 Apr 10.

Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00439-018-1881-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209094PMC
April 2018

WISARD: workbench for integrated superfast association studies for related datasets.

BMC Med Genomics 2018 04 20;11(Suppl 2):39. Epub 2018 Apr 20.

Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, South Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12920-018-0345-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918457PMC
April 2018

F-FDG PET/CT findings in hepatosplenic Gamma-Delta T-cell lymphoma: case reports and review of the literature.

Am J Nucl Med Mol Imaging 2018 25;8(2):137-142. Epub 2018 Apr 25.

Department of Radiology, University of Colorado Aurora, Colorado, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944829PMC
April 2018

Integrative genomics identifies new genes associated with severe COPD and emphysema.

Respir Res 2018 03 22;19(1):46. Epub 2018 Mar 22.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Room 451, Boston, MA, 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12931-018-0744-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863845PMC
March 2018

Surfactant Copolymer Annealing of Chemically Permeabilized Cell Membranes.

Regen Eng Transl Med 2018 Mar 27;4(1):1-10. Epub 2018 Mar 27.

Department of Surgery, University of Chicago, Chicago, IL, USA, 60637.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40883-017-0044-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426139PMC
March 2018

Reparative Effects of Poloxamer P188 in Astrocytes Exposed to Controlled Microcavitation.

Ann Biomed Eng 2018 Feb 6;46(2):354-364. Epub 2017 Nov 6.

Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, 60607, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10439-017-1953-yDOI Listing
February 2018

Lobar Emphysema Distribution Is Associated With 5-Year Radiological Disease Progression.

Chest 2018 01 21;153(1):65-76. Epub 2017 Sep 21.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Division of General Medicine and Primary Care, Brigham and Women's Hospital, Harvard Medical School, Boston, MA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chest.2017.09.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026264PMC
January 2018

Proatherogenic Flow Increases Endothelial Stiffness via Enhanced CD36-Mediated Uptake of Oxidized Low-Density Lipoproteins.

Arterioscler Thromb Vasc Biol 2018 01 12;38(1):64-75. Epub 2017 Oct 12.

From the Division of Pulmonary and Critical Care (E.L.M., C.Z., T.-P.S., I.S.F., I.L.), Division of Endocrinology (P.V.S.), Division of Hematology and Oncology, Department of Medicine (Y.S., Z.Q.), and Departments of Bioengineering (E.L.M., T.-P.S., C.N., T.C., D.T.E., J.L., M.C., I.L.), Pharmacology (Y.B., C.C., R.D.M., I.L.), and Anesthesiology (R.D.M.), University of Illinois at Chicago; Department of Medicine, University of Chicago, IL (R.-T.H., Y.F.); and Division of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, CO (E.B.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.117.309907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746473PMC
January 2018

What do polymorphisms tell us about the mechanisms of COPD?

Clin Sci (Lond) 2017 Dec 4;131(24):2847-2863. Epub 2017 Dec 4.

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, U.S.A.

View Article

Download full-text PDF

Source
http://clinsci.org/lookup/doi/10.1042/CS20160718
Publisher Site
http://dx.doi.org/10.1042/CS20160718DOI Listing
December 2017

The value of blood cytokines and chemokines in assessing COPD.

Respir Res 2017 10 24;18(1):180. Epub 2017 Oct 24.

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, National Jewish Health, 1400 Jackson St., K715, Denver, CO, 80206, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12931-017-0662-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655820PMC
October 2017

Screening for interaction effects in gene expression data.

PLoS One 2017 16;12(3):e0173847. Epub 2017 Mar 16.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0173847PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354413PMC
September 2017

Selecting cases and controls for DNA sequencing studies using family histories of disease.

Stat Med 2017 06 21;36(13):2081-2099. Epub 2017 Feb 21.

Interdisciplinary Program of Bioinformatics, Seoul National University, Seoul, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/sim.7248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810411PMC
June 2017

A Likelihood-Free Approach for Characterizing Heterogeneous Diseases in Large-Scale Studies.

Inf Process Med Imaging 2017 Jun 23;10265:170-183. Epub 2017 May 23.

Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-3-319-59050-9_14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679301PMC
June 2017

Gene-based segregation method for identifying rare variants in family-based sequencing studies.

Genet Epidemiol 2017 05 13;41(4):309-319. Epub 2017 Feb 13.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gepi.22037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397337PMC
May 2017

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.

Authors:
Philip C Haycock Stephen Burgess Aayah Nounu Jie Zheng George N Okoli Jack Bowden Kaitlin Hazel Wade Nicholas J Timpson David M Evans Peter Willeit Abraham Aviv Tom R Gaunt Gibran Hemani Massimo Mangino Hayley Patricia Ellis Kathreena M Kurian Karen A Pooley Rosalind A Eeles Jeffrey E Lee Shenying Fang Wei V Chen Matthew H Law Lisa M Bowdler Mark M Iles Qiong Yang Bradford B Worrall Hugh Stephen Markus Rayjean J Hung Chris I Amos Amanda B Spurdle Deborah J Thompson Tracy A O'Mara Brian Wolpin Laufey Amundadottir Rachael Stolzenberg-Solomon Antonia Trichopoulou N Charlotte Onland-Moret Eiliv Lund Eric J Duell Federico Canzian Gianluca Severi Kim Overvad Marc J Gunter Rosario Tumino Ulrika Svenson Andre van Rij Annette F Baas Matthew J Bown Nilesh J Samani Femke N G van t'Hof Gerard Tromp Gregory T Jones Helena Kuivaniemi James R Elmore Mattias Johansson James Mckay Ghislaine Scelo Robert Carreras-Torres Valerie Gaborieau Paul Brennan Paige M Bracci Rachel E Neale Sara H Olson Steven Gallinger Donghui Li Gloria M Petersen Harvey A Risch Alison P Klein Jiali Han Christian C Abnet Neal D Freedman Philip R Taylor John M Maris Katja K Aben Lambertus A Kiemeney Sita H Vermeulen John K Wiencke Kyle M Walsh Margaret Wrensch Terri Rice Clare Turnbull Kevin Litchfield Lavinia Paternoster Marie Standl Gonçalo R Abecasis John Paul SanGiovanni Yong Li Vladan Mijatovic Yadav Sapkota Siew-Kee Low Krina T Zondervan Grant W Montgomery Dale R Nyholt David A van Heel Karen Hunt Dan E Arking Foram N Ashar Nona Sotoodehnia Daniel Woo Jonathan Rosand Mary E Comeau W Mark Brown Edwin K Silverman John E Hokanson Michael H Cho Jennie Hui Manuel A Ferreira Philip J Thompson Alanna C Morrison Janine F Felix Nicholas L Smith Angela M Christiano Lynn Petukhova Regina C Betz Xing Fan Xuejun Zhang Caihong Zhu Carl D Langefeld Susan D Thompson Feijie Wang Xu Lin David A Schwartz Tasha Fingerlin Jerome I Rotter Mary Frances Cotch Richard A Jensen Matthias Munz Henrik Dommisch Arne S Schaefer Fang Han Hanna M Ollila Ryan P Hillary Omar Albagha Stuart H Ralston Chenjie Zeng Wei Zheng Xiao-Ou Shu Andre Reis Steffen Uebe Ulrike Hüffmeier Yoshiya Kawamura Takeshi Otowa Tsukasa Sasaki Martin Lloyd Hibberd Sonia Davila Gang Xie Katherine Siminovitch Jin-Xin Bei Yi-Xin Zeng Asta Försti Bowang Chen Stefano Landi Andre Franke Annegret Fischer David Ellinghaus Carlos Flores Imre Noth Shwu-Fan Ma Jia Nee Foo Jianjun Liu Jong-Won Kim David G Cox Olivier Delattre Olivier Mirabeau Christine F Skibola Clara S Tang Merce Garcia-Barcelo Kai-Ping Chang Wen-Hui Su Yu-Sun Chang Nicholas G Martin Scott Gordon Tracey D Wade Chaeyoung Lee Michiaki Kubo Pei-Chieng Cha Yusuke Nakamura Daniel Levy Masayuki Kimura Shih-Jen Hwang Steven Hunt Tim Spector Nicole Soranzo Ani W Manichaikul R Graham Barr Bratati Kahali Elizabeth Speliotes Laura M Yerges-Armstrong Ching-Yu Cheng Jost B Jonas Tien Yin Wong Isabella Fogh Kuang Lin John F Powell Kenneth Rice Caroline L Relton Richard M Martin George Davey Smith

JAMA Oncol 2017 May;3(5):636-651

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaoncol.2016.5945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638008PMC
May 2017

Progress in disease progression genetics: dissecting the genetic origins of lung function decline in COPD.

Thorax 2017 05 14;72(5):389-390. Epub 2017 Mar 14.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/thoraxjnl-2016-209666DOI Listing
May 2017

On the association analysis of genome-sequencing data: A spatial clustering approach for partitioning the entire genome into nonoverlapping windows.

Genet Epidemiol 2017 05 20;41(4):332-340. Epub 2017 Mar 20.

Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gepi.22040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525021PMC
May 2017

Preventive Effects of Poloxamer 188 on Muscle Cell Damage Mechanics Under Oxidative Stress.

Ann Biomed Eng 2017 04 20;45(4):1083-1092. Epub 2016 Sep 20.

Division of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, NT, Hong Kong.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10439-016-1733-0DOI Listing
April 2017

Effects of direct current electric fields on lung cancer cell electrotaxis in a PMMA-based microfluidic device.

Anal Bioanal Chem 2017 Mar 11;409(8):2163-2178. Epub 2017 Jan 11.

Department of Biomedical Sciences, City University of Hong Kong, 31 To Yuen Street, Kowloon Tong, Hong Kong, 999077, China.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00216-016-0162-0
Publisher Site
http://dx.doi.org/10.1007/s00216-016-0162-0DOI Listing
March 2017

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.

Authors:
Louise V Wain Nick Shrine María Soler Artigas A Mesut Erzurumluoglu Boris Noyvert Lara Bossini-Castillo Ma'en Obeidat Amanda P Henry Michael A Portelli Robert J Hall Charlotte K Billington Tracy L Rimington Anthony G Fenech Catherine John Tineka Blake Victoria E Jackson Richard J Allen Bram P Prins Archie Campbell David J Porteous Marjo-Riitta Jarvelin Matthias Wielscher Alan L James Jennie Hui Nicholas J Wareham Jing Hua Zhao James F Wilson Peter K Joshi Beate Stubbe Rajesh Rawal Holger Schulz Medea Imboden Nicole M Probst-Hensch Stefan Karrasch Christian Gieger Ian J Deary Sarah E Harris Jonathan Marten Igor Rudan Stefan Enroth Ulf Gyllensten Shona M Kerr Ozren Polasek Mika Kähönen Ida Surakka Veronique Vitart Caroline Hayward Terho Lehtimäki Olli T Raitakari David M Evans A John Henderson Craig E Pennell Carol A Wang Peter D Sly Emily S Wan Robert Busch Brian D Hobbs Augusto A Litonjua David W Sparrow Amund Gulsvik Per S Bakke James D Crapo Terri H Beaty Nadia N Hansel Rasika A Mathias Ingo Ruczinski Kathleen C Barnes Yohan Bossé Philippe Joubert Maarten van den Berge Corry-Anke Brandsma Peter D Paré Don D Sin David C Nickle Ke Hao Omri Gottesman Frederick E Dewey Shannon E Bruse David J Carey H Lester Kirchner Stefan Jonsson Gudmar Thorleifsson Ingileif Jonsdottir Thorarinn Gislason Kari Stefansson Claudia Schurmann Girish Nadkarni Erwin P Bottinger Ruth J F Loos Robin G Walters Zhengming Chen Iona Y Millwood Julien Vaucher Om P Kurmi Liming Li Anna L Hansell Chris Brightling Eleftheria Zeggini Michael H Cho Edwin K Silverman Ian Sayers Gosia Trynka Andrew P Morris David P Strachan Ian P Hall Martin D Tobin

Nat Genet 2017 Mar 6;49(3):416-425. Epub 2017 Feb 6.

Department of Health Sciences, University of Leicester, Leicester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326681PMC
March 2017

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.

Nat Genet 2017 Mar 6;49(3):426-432. Epub 2017 Feb 6.

Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381275PMC
March 2017

Focal Breast Pain: Does Breast Density Affect the Need for Ultrasound?

Acad Radiol 2017 01 13;24(1):53-59. Epub 2016 Oct 13.

Division of Breast Imaging, Department of Radiology, Duke University Medical Center, Box 3808, Erwin Road, Durham, NC 27710.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.acra.2016.09.004DOI Listing
January 2017

Molecular-Scale Biophysical Modulation of an Endothelial Membrane by Oxidized Phospholipids.

Biophys J 2017 Jan;112(2):325-338

Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bpj.2016.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266087PMC
January 2017

Whole genome prediction and heritability of childhood asthma phenotypes.

Immun Inflamm Dis 2016 12 28;4(4):487-496. Epub 2016 Nov 28.

Channing Division of Network Medicine Brigham and Women's Hospital and Harvard Medical School Boston Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/iid3.133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134727PMC
December 2016

Boosting Gene Mapping Power and Efficiency with Efficient Exact Variance Component Tests of Single Nucleotide Polymorphism Sets.

Genetics 2016 11 19;204(3):921-931. Epub 2016 Sep 19.

Department of Biostatistics, University of California, Los Angeles, California 90095.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1534/genetics.116.190454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105869PMC
November 2016

Drosophila IRBP bZIP heterodimer binds P-element DNA and affects hybrid dysgenesis.

Proc Natl Acad Sci U S A 2016 11 31;113(46):13003-13008. Epub 2016 Oct 31.

Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1613508113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135294PMC
November 2016

Increasing Generality and Power of Rare-Variant Tests by Utilizing Extended Pedigrees.

Am J Hum Genet 2016 Oct 22;99(4):846-859. Epub 2016 Sep 22.

Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2016.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065687PMC
October 2016

Transient Biocompatible Polymeric Platforms for Long-Term Controlled Release of Therapeutic Proteins and Vaccines.

Materials (Basel) 2016 May 28;9(5). Epub 2016 Apr 28.

Department of Mechanical Engineering, Iowa State University, Ames, IA 50011, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ma9050321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441878PMC
May 2016

Genetic regulation of expression of leukotriene A4 hydrolase.

ERJ Open Res 2016 Jan 9;2(1). Epub 2016 Feb 9.

Dept of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; Program in Protease and Matrix Biology, University of Alabama at Birmingham, Birmingham, AL, USA; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, USA; Lung Health Center, University of Alabama at Birmingham, Birmingham, AL, USA; Medicine Service, United States Department of Veterans Affairs Medical Center, University of Alabama at Birmingham, Birmingham, AL, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/23120541.00058-2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005155PMC
January 2016