College of Charleston
Charleston, SC | United States
Main Specialties: Biology
Additional Specialties: Biomedical Physics
Mike Carnohan graduated from the College of Charleston with a B.S. in Physics, with an emphasis in BioMedical Physics, in 2001. While attending the College of Charleston, he was a member of the national Physics honor society, Sigma Pi Sigma, and published several papers in the fields of applied optics & photonics. After his undergraduate studies, he studied Interactive Design at Trident Technical College, and worked as UX Designer for Accomplice Design in Charleston, SC before moving to San Diego, CA to work for a forward-thinking 501(c)3 software development company, Pangea Foundation. There he functioned as the operational lead of software development in the role Sr. Vice President of Product & Strategy, until 2013. He founded the mobile sharing startup, Neighbr, in late 2013, and served as the Director Of Operations of the A/V production company, HiFi5 Entertainment, from 2014 - 2016. In 2016, he joined Hair Science, a research and development pharmaceutical company, as the Director of Markets & Research. He currently lives in Santa Cruz, CA and works for Hair Science, and is the Founder and Lead Designer of the Santa Cruz-based apparel company, Alpha Thread.
Primary Affiliation: College of Charleston - Charleston, SC , United States
PubMed Central Citations
12PubMed Central Citations
Proc. SPIE 4958, Advanced Biomedical and Clinical Diagnostic Systems, 43 (July 22, 2003)
Proceedings of the SPIE
The design of fiber-optic probes plays an important role in optical spectroscopic studies, including fluorescence spectroscopy of biological tissues. It can affect the light delivery and propagation into the tissue, the collection efficiency (total number of photons collected vs. total number of photons launched) and the origin of collected light. This in turn affects the signal to noise ratio (SNR) and the extend of tissue interrogation, thus influencing the diagnostic value of such techniques. Three specific fiber-optic probe designs were tested both experimentally and computationally via Monte Carlo simulations. In particular, the effects of probe architecture (single-fiber vs. two bifurcated multifiber probes), probe-to-target distance (PTD), and source-to-detector separation (SDS) were investigated on the collected diffuse reflectance of a Lambertian target and an agar-based tissue phantom. This study demonstrated that probe architecture, PTD, and SDS are closely intertwined and considerably affect the light collection efficiency, the extend of target illumination, and the origin of the collected reflected light. Our findings can be applied towards optimization of fiber-optic probe designs for quantitative fluorescence spectroscopy of diseased tissues.
Lasers Surg Med, Surgical Applications 2003 Mar; 32(S15):50.
Lasers in Surgery and Medicine
Successful application of fiberoptically-based biologic spectroscopic techniques requires understanding of the interrelation between probe design, application geometry, and target optical properties. To this end, we conducted experimental and computational studies of the performance of three probe designs with various targets, as a function of the probe-to-target separation.