Publications by authors named "Michael Caplan"

100Publications

Grading the evidence to identify strategies to modify risk for necrotizing enterocolitis.

Pediatr Res 2020 08;88(Suppl 1):41-47

Department of Pediatrics, Northshore Research Institute, Chicago, IL, USA.

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http://dx.doi.org/10.1038/s41390-020-1079-zDOI Listing
August 2020

Defining necrotizing enterocolitis: current difficulties and future opportunities.

Pediatr Res 2020 08;88(Suppl 1):10-15

Department of Pediatrics, NorthShore University Health System, Evanston, IL, USA.

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http://dx.doi.org/10.1038/s41390-020-1074-4DOI Listing
August 2020

Neutrophil extracellular trap inhibition increases inflammation, bacteraemia and mortality in murine necrotizing enterocolitis.

J Cell Mol Med 2020 Jun 8. Epub 2020 Jun 8.

Oklahoma Medical Research Foundation, Cardiovascular Biology Research Program, Oklahoma City, OK, USA.

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http://dx.doi.org/10.1111/jcmm.15338DOI Listing
June 2020

A cut above (and below): Protein cleavage in the regulation of polycystin trafficking and signaling.

Cell Signal 2020 Aug 10;72:109634. Epub 2020 Apr 10.

Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520-8026, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2020.109634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269866PMC
August 2020

Mechanisms involved in AMPK-mediated deposition of tight junction components to the plasma membrane.

Am J Physiol Cell Physiol 2020 03 8;318(3):C486-C501. Epub 2020 Jan 8.

Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1152/ajpcell.00422.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099514PMC
March 2020

Holding open the door reveals a new view of polycystin channel function.

Authors:
Michael J Caplan

EMBO Rep 2019 11 26;20(11):e49156. Epub 2019 Sep 26.

Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.15252/embr.201949156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832007PMC
November 2019

Necrotizing Enterocolitis: Using Regulatory Science and Drug Development to Improve Outcomes.

J Pediatr 2019 09 22;212:208-215.e1. Epub 2019 Jun 22.

Department of Pediatrics, The Floating Hospital for Children at Tufts Medical Center, Boston, MA; The Tufts Clinical and Translational Research Institute, Boston, MA.

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http://dx.doi.org/10.1016/j.jpeds.2019.05.032DOI Listing
September 2019

Everything You Always Wanted to Know about β-AR * (* But Were Afraid to Ask).

Cells 2019 04 16;8(4). Epub 2019 Apr 16.

Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06510, USA.

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https://www.mdpi.com/2073-4409/8/4/357
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http://dx.doi.org/10.3390/cells8040357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523418PMC
April 2019

Improving Outcomes Due to Neonatal Necrotizing Enterocolitis.

Authors:
Michael S Caplan

Clin Perinatol 2019 03 14;46(1):xvii-xviii. Epub 2018 Dec 14.

Department of Pediatrics, North Shore University Health System, Evanston Hospital, 2650 Ridge Avenue, Evanston, IL 60201, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clp.2018.12.001DOI Listing
March 2019

Oropharyngeal Mother's Milk: State of the Science and Influence on Necrotizing Enterocolitis.

Clin Perinatol 2019 03 13;46(1):77-88. Epub 2018 Dec 13.

Department of Pediatrics, NorthShore University HealthSystem, Evanston Hospital, 2650 Ridge Avenue, Evanston, IL 60201, USA; Pritzker School of Medicine, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.clp.2018.09.005DOI Listing
March 2019

Can Fish Oil Reduce the Incidence of Necrotizing Enterocolitis by Altering the Inflammatory Response?

Clin Perinatol 2019 03 12;46(1):65-75. Epub 2018 Dec 12.

Department of Pediatrics, NorthShore University HealthSystem, University of Chicago Pritzker School of Medicine, 2650 Ridge Avenue, Walgreen Building Suite 1505, Evanston, IL 60201, USA.

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http://dx.doi.org/10.1016/j.clp.2018.09.004DOI Listing
March 2019

The Polycystin Complex Reveals Its Complexity.

Biochemistry 2018 12 12;57(51):6917-6918. Epub 2018 Dec 12.

Department of Cellular and Molecular Physiology , Yale University School of Medicine , P.O. Box 208026, New Haven , Connecticut 06520-8026 , United States.

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http://dx.doi.org/10.1021/acs.biochem.8b01205DOI Listing
December 2018

Newly synthesized polycystin-1 takes different trafficking pathways to the apical and ciliary membranes.

Traffic 2018 12 24;19(12):933-945. Epub 2018 Sep 24.

Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1111/tra.12612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237641PMC
December 2018

Metabolism and mitochondria in polycystic kidney disease research and therapy.

Nat Rev Nephrol 2018 11;14(11):678-687

Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1038/s41581-018-0051-1DOI Listing
November 2018

Microbiota influence the development of the brain and behaviors in C57BL/6J mice.

PLoS One 2018 3;13(8):e0201829. Epub 2018 Aug 3.

Department of Pediatrics, NorthShore University HealthSystem Research Institute, Evanston, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201829PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075787PMC
February 2019

In Vitro Validation of Targeting and Comparison to Mathematical Modeling.

Methods Mol Biol 2018 ;1831:121-141

School of Biological and Health Systems Engineering, Fulton Schools of Engineering, Arizona State University, Tempe, AZ, USA.

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http://dx.doi.org/10.1007/978-1-4939-8661-3_10DOI Listing
April 2019

Implications of AMPK in the Formation of Epithelial Tight Junctions.

Int J Mol Sci 2018 Jul 13;19(7). Epub 2018 Jul 13.

Groupe Interdisciplinaire de Génoprotéomique Appliquée (GIGA), Cardiovascular Sciences, University of Liège (ULiège), Avenue de L'Hôpital 11, 4000 Liège, Belgium.

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http://dx.doi.org/10.3390/ijms19072040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073107PMC
July 2018

Tandem Histone-Binding Domains Enhance the Activity of a Synthetic Chromatin Effector.

ACS Synth Biol 2018 03 23;7(3):842-852. Epub 2018 Feb 23.

School of Biological and Health Systems Engineering , Arizona State University , Tempe , Arizona 85287-9709 , United States.

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http://dx.doi.org/10.1021/acssynbio.7b00281DOI Listing
March 2018

Necrotizing enterocolitis: Pathophysiology from a historical context.

Semin Pediatr Surg 2018 Feb 6;27(1):11-18. Epub 2017 Nov 6.

North Shore University Health System and the University of Chicago Pritzker School of Medicine, Chicago, IL.

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http://dx.doi.org/10.1053/j.sempedsurg.2017.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207945PMC
February 2018

Paediatrics: Are human milk oligosaccharides the magic bullet for necrotizing enterocolitis?

Authors:
Michael S Caplan

Nat Rev Gastroenterol Hepatol 2017 07 17;14(7):394-395. Epub 2017 May 17.

Department of Pediatrics, NorthShore University HealthSystem, Evanston Hospital, 2650 Ridge Avenue, Evanston, Illinois 60201, USA.

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http://dx.doi.org/10.1038/nrgastro.2017.65DOI Listing
July 2017

The secretory pathway at 50: a golden anniversary for some momentous grains of silver.

Mol Biol Cell 2017 01;28(2):229-232

Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520-8026

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http://dx.doi.org/10.1091/mbc.E16-07-0508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231891PMC
January 2017

New Medical and Surgical Insights Into Neonatal Necrotizing Enterocolitis: A Review.

JAMA Pediatr 2017 01;171(1):83-88

Department of Pediatrics, NorthShore University HealthSystem, Evanston, Illinois2University of Chicago Pritzker School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1001/jamapediatrics.2016.2708DOI Listing
January 2017

Introduction.

Authors:
Michael S Caplan

Semin Perinatol 2017 02 8;41(1). Epub 2016 Nov 8.

Chairman Department of Pediatrics, Chief Scientific Officer Northshore University Healthsystem.

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http://dx.doi.org/10.1053/j.semperi.2016.09.011DOI Listing
February 2017

Necrotizing: A historical perspective.

Semin Perinatol 2017 02 8;41(1):2-6. Epub 2016 Nov 8.

Eliza Henry Barnes chair in Neonatology, Rainbow Babies and Children's Hospital.

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http://dx.doi.org/10.1053/j.semperi.2016.09.012DOI Listing
February 2017

Feasibility in the development of a multi-marker detection platform.

Biosens Bioelectron 2017 Mar 27;89(Pt 2):743-749. Epub 2016 Oct 27.

Harrington Program of Biomedical Engineering, in the School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ 85287, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09565663163111
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http://dx.doi.org/10.1016/j.bios.2016.10.073DOI Listing
March 2017

Newly synthesized and recycling pools of the apical protein gp135 do not occupy the same compartments.

Traffic 2016 12 1;17(12):1272-1285. Epub 2016 Nov 1.

Department of Cellular and Molecular Physiology and Department of Cell Biology, Yale University School of Medicine, New Haven, CT.

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http://dx.doi.org/10.1111/tra.12449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123909PMC
December 2016

Early docosahexaenoic and arachidonic acid supplementation in extremely-low-birth-weight infants.

Pediatr Res 2016 10 3;80(4):505-10. Epub 2016 Jun 3.

Department of Pediatrics, NorthShore University HealthSystem, Pritzker School of Medicine, University of Chicago, Evanston, Illinois.

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http://dx.doi.org/10.1038/pr.2016.118DOI Listing
October 2016

A Practical Forensic Approach to Fatal Pediatric Endocrinopathies.

Authors:
Michael J Caplan

Acad Forensic Pathol 2016 Jun 1;6(2):258-270. Epub 2016 Jun 1.

Suffolk County Office of the Medical Examiner and Stony Brook University Health Sciences Center School of Medicine - Pathology.

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http://dx.doi.org/10.23907/2016.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506994PMC
June 2016

Artificial bacterial biomimetic nanoparticles synergize pathogen-associated molecular patterns for vaccine efficacy.

Biomaterials 2016 08 1;97:85-96. Epub 2016 Apr 1.

Department of Biomedical Engineering, Yale University, New Haven, CT 06520, USA; Department of Chemical and Environmental Engineering, Yale University, New Haven, CT 06520, USA; Department of Immunobiology, Yale University, New Haven, CT 06520, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01429612163007
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http://dx.doi.org/10.1016/j.biomaterials.2016.03.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999034PMC
August 2016

Investigation of peanut oral immunotherapy with CpG/peanut nanoparticles in a murine model of peanut allergy.

J Allergy Clin Immunol 2016 08 26;138(2):536-543.e4. Epub 2016 Apr 26.

Pediatric Allergy and Immunology, Icahn School of Medicine at Mount Sinai, New York, NY; Jaffe Food Allergy Institute, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.01.047DOI Listing
August 2016

The tail of polycystin-1 pays the kidney a complement.

Authors:
Michael J Caplan

Am J Physiol Renal Physiol 2016 06 23;310(11):F1180-1. Epub 2016 Mar 23.

Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut

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http://www.physiology.org/doi/10.1152/ajprenal.00141.2016
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http://dx.doi.org/10.1152/ajprenal.00141.2016DOI Listing
June 2016

2016 Robert W. Berliner Award for Excellence in Renal Physiology.

Authors:
Michael J Caplan

Am J Physiol Renal Physiol 2016 04 9;310(8):F803-F804. Epub 2016 Mar 9.

Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1152/ajprenal.00128.2016DOI Listing
April 2016

The periciliary ring in polarized epithelial cells is a hot spot for delivery of the apical protein gp135.

J Cell Biol 2015 Oct;211(2):287-94

Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06520 Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520

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http://dx.doi.org/10.1083/jcb.201502045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621837PMC
October 2015

Dual pulse-chase microscopy reveals early divergence in the biosynthetic trafficking of the Na,K-ATPase and E-cadherin.

Mol Biol Cell 2015 Dec 30;26(24):4401-11. Epub 2015 Sep 30.

Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520-8026

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http://dx.doi.org/10.1091/mbc.E14-09-1385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666135PMC
December 2015

Polycystin-1 Is a Cardiomyocyte Mechanosensor That Governs L-Type Ca2+ Channel Protein Stability.

Circulation 2015 Jun 17;131(24):2131-42. Epub 2015 Apr 17.

From Division of Cardiology, Department of Internal Medicine (Z.P., A.C., P.K.B., C.R.M., N.J., X.L., B.A.R., T.G.G., S.L., J.A.H.) and Department of Molecular Biology (B.A.R., J.A.H.), UT Southwestern Medical Center, Dallas, TX; Advanced Center for Chronic Diseases and Centro de Estudios Moleculares de la Célula, Facultad de Medicina & Facultad de Ciencias Químicas y Farmacéuticas, Santiago, Chile (Z.P., A.C.-F., C.F., S.L.); Instituto de Ciencias Biomédicas, Facultad de Medicina (Z.P., S.L.) and Instituto de Investigación en Ciencias Odontológicas, Facultad de Odontología (A.C.), Universidad de Chile, Santiago; and Departments of Cellular and Molecular Physiology (M.J.C.), Internal Medicine (S.S.), and Genetics (S.S.), Yale University School of Medicine, New Haven, CT.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.013537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470854PMC
June 2015

Oropharyngeal administration of mother's milk to prevent necrotizing enterocolitis in extremely low-birth-weight infants: theoretical perspectives.

J Perinat Neonatal Nurs 2015 Jan-Mar;29(1):81-90

Department of Pediatrics, NorthShore University HealthSystem, 2650 Ridge Ave, Evanston, IL 60201.

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http://dx.doi.org/10.1097/JPN.0000000000000087DOI Listing
November 2016

Developmental lung malformations in children: recent advances in imaging techniques, classification system, and imaging findings.

J Thorac Imaging 2015 Jan;30(1):29-43; quiz 44-5

*Assistant Professor of Radiology and Radiological Science ‡Associate Professor of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC †Pediatric Radiology Fellow, Department of Radiology §Chief of Division of Thoracic Imaging, Director of Magnetic Resonance Imaging, Department of Radiology, Boston Children's Hospital and Harvard Medical School, Boston, MA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/RTI.0000000000000125DOI Listing
January 2015

Linking fat intake, the intestinal microbiome, and necrotizing enterocolitis in premature infants.

Pediatr Res 2015 Jan 10;77(1-2):121-6. Epub 2014 Oct 10.

Department of Pediatrics, Northshore University Health System, Pritzker School of Medicine, University of Chicago, Evanston, Illinois.

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http://dx.doi.org/10.1038/pr.2014.155DOI Listing
January 2015

Chemical and Physical Sensors in the Regulation of Renal Function.

Clin J Am Soc Nephrol 2015 Sep 3;10(9):1626-35. Epub 2014 Oct 3.

Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut

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http://dx.doi.org/10.2215/CJN.00730114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559500PMC
September 2015

Incidental mucocele of the appendix in a 15-year-old girl.

Pediatr Emerg Care 2014 Aug;30(8):555-7

From the Departments of *Pediatric Radiology, †Pediatric Surgery, ‡Pediatric Emergency Medicine, and §Pathology, Medical University of South Carolina, Charleston, SC.

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http://pdfs.journals.lww.com/pec-online/2014/08000/Incidenta
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PEC.0000000000000187DOI Listing
August 2014

Maternal breast milk transforming growth factor-beta and feeding intolerance in preterm infants.

Pediatr Res 2014 Oct 4;76(4):386-93. Epub 2014 Jul 4.

1] Department of Pediatrics, NorthShore University HealthSystem, Evanston, Illinois [2] University of Chicago Pritzker School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1038/pr.2014.96DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467901PMC
October 2014

SNAP-tag to monitor trafficking of membrane proteins in polarized epithelial cells.

Methods Mol Biol 2014 ;1174:171-82

Department of Cellular & Molecular Physiology, Yale University School of Medicine, 208026, New Haven, CT, 06520-8026, USA,

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http://dx.doi.org/10.1007/978-1-4939-0944-5_11DOI Listing
January 2015

Trafficking to the apical and basolateral membranes in polarized epithelial cells.

J Am Soc Nephrol 2014 Jul 20;25(7):1375-86. Epub 2014 Mar 20.

Departments of Cellular & Molecular Physiology and Cell Biology, Yale University School of Medicine, New Haven, Connecticut

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http://dx.doi.org/10.1681/ASN.2013080883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073435PMC
July 2014

A growing lesion on the cheek.

JAMA Otolaryngol Head Neck Surg 2014 Apr;140(4):383-4

Medical University of South Carolina, Charleston.

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http://dx.doi.org/10.1001/jamaoto.2013.6770DOI Listing
April 2014

Antimicrobial distribution from local delivery depends on dose : a pilot study with MRI.

Clin Orthop Relat Res 2014 Nov;472(11):3324-9

Banner Good Samaritan Orthopaedic Residency, Banner Good Samaritan Medical Center, 901 E Willetta Road, 2nd Floor, Phoenix, AZ, 85006, USA.

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http://dx.doi.org/10.1007/s11999-014-3493-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182417PMC
November 2014

The role of SDF-1α-ECM crosstalk in determining neural stem cell fate.

Biomaterials 2014 Mar 15;35(10):3263-72. Epub 2014 Jan 15.

School of Biological and Health Systems Engineering, Arizona State University, P.O. Box 879709, Tempe, AZ 85287-9709, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01429612130159
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http://dx.doi.org/10.1016/j.biomaterials.2013.12.102DOI Listing
March 2014

Distribution of molecules locally delivered from bone cement.

J Biomed Mater Res B Appl Biomater 2014 May 24;102(4):806-14. Epub 2013 Oct 24.

Center for Interventional Biomaterials, School of Biological and Health Systems Engineering, Arizona State University, Tempe, Arizona.

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http://dx.doi.org/10.1002/jbm.b.33062DOI Listing
May 2014

Activation of the Ca²+-sensing receptor induces deposition of tight junction components to the epithelial cell plasma membrane.

J Cell Sci 2013 Nov 6;126(Pt 22):5132-42. Epub 2013 Sep 6.

Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1242/jcs.127555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828589PMC
November 2013

Polycystin-1 cleavage and the regulation of transcriptional pathways.

Pediatr Nephrol 2014 Apr 4;29(4):505-11. Epub 2013 Jul 4.

Department of Cellular and Molecular Physiology, Yale University School of Medicine, P.O. Box 208026, New Haven, CT, 06520-8026, USA.

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http://dx.doi.org/10.1007/s00467-013-2548-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844055PMC
April 2014

Spatiotemporal quantification of local drug delivery using MRI.

Comput Math Methods Med 2013 24;2013:149608. Epub 2013 Apr 24.

Center for Interventional Biomaterials, School of Biological and Health Systems Engineering, Arizona State University, P.O. Box 879709, Tempe, AZ 85287, USA.

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http://dx.doi.org/10.1155/2013/149608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655453PMC
December 2013

An inversin convergence. Focus on "Inversin modulates the cortical actin network during mitosis".

Authors:
Michael J Caplan

Am J Physiol Cell Physiol 2013 Jul 15;305(1):C22-3. Epub 2013 May 15.

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http://dx.doi.org/10.1152/ajpcell.00126.2013DOI Listing
July 2013

Necrotizing enterocolitis: pathophysiology, platelet-activating factor, and probiotics.

Semin Pediatr Surg 2013 May;22(2):88-93

Department of Pediatrics, NorthShore University HealthSystem, Pritzker School of Medicine, University of Chicago, 2650 Ridge Ave, Walgreen Building, Suite 1505, Evanston, Illinois, USA.

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http://dx.doi.org/10.1053/j.sempedsurg.2013.01.005DOI Listing
May 2013

Polycystin-1C terminus cleavage and its relation with polycystin-2, two proteins involved in polycystic kidney disease.

Medicina (B Aires) 2013 ;73(2):155-62

Department of Cell Biology and Physiology, University of Pittsburgh, Pittsburgh, PA, USA.

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June 2014

Efficacy of different probiotic combinations on death and necrotizing enterocolitis in a premature rat model.

J Pediatr Gastroenterol Nutr 2013 Jul;57(1):23-8

Department of Pediatrics, China Medical University Hospital, Taichung, Taiwan.

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http://dx.doi.org/10.1097/MPG.0b013e3182929210DOI Listing
July 2013

An incubatable direct current stimulation system for in vitro studies of Mammalian cells.

Biores Open Access 2012 Aug;1(4):199-203

School of Biological and Health Systems Engineering, Arizona State University , Tempe, Arizona.

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http://dx.doi.org/10.1089/biores.2012.0233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559215PMC
August 2012

Epithelial morphogenesis of MDCK cells in three-dimensional collagen culture is modulated by interleukin-8.

Am J Physiol Cell Physiol 2013 May 13;304(10):C966-75. Epub 2013 Mar 13.

Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1152/ajpcell.00261.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651639PMC
May 2013

A rapidly expanding orbital lesion.

J Pediatr 2013 Jul 28;163(1):294-5.e1-2. Epub 2013 Feb 28.

Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.

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http://dx.doi.org/10.1016/j.jpeds.2013.01.038DOI Listing
July 2013

Heterobivalent ligands target cell-surface receptor combinations in vivo.

Proc Natl Acad Sci U S A 2012 Dec 10;109(52):21295-300. Epub 2012 Dec 10.

Department of Cancer Imaging and Metabolism, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1073/pnas.1211762109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535626PMC
December 2012

Murine gut microbiota and transcriptome are diet dependent.

Ann Surg 2013 Feb;257(2):287-94

Department of Surgery, The University of Chicago Medical Center, Chicago, IL 60637, USA.

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https://insights.ovid.com/crossref?an=00000658-201302000-000
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http://dx.doi.org/10.1097/SLA.0b013e318262a6a6DOI Listing
February 2013

VIP17/MAL expression modulates epithelial cyst formation and ciliogenesis.

Am J Physiol Cell Physiol 2012 Oct 15;303(8):C862-71. Epub 2012 Aug 15.

Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, Connecticut 06520-8026, USA.

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http://dx.doi.org/10.1152/ajpcell.00338.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469709PMC
October 2012

Docosahexaenoic and arachidonic acid levels in extremely low birth weight infants with prolonged exposure to intravenous lipids.

J Pediatr 2013 Jan 9;162(1):56-61. Epub 2012 Aug 9.

Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/j.jpeds.2012.06.045DOI Listing
January 2013

Necrotizing enterocolitis: old problem with new hope.

Pediatr Neonatol 2012 Jun 8;53(3):158-63. Epub 2012 Jun 8.

Department of Pediatrics, China Medical University Hospital, China Medical University, Taichung, Taiwan.

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http://dx.doi.org/10.1016/j.pedneo.2012.04.001DOI Listing
June 2012

Intracellular signaling controls endothelial cell prostacyclin secretion and regulation of blood clotting time.

J Biomed Mater Res A 2012 Dec 6;100(12):3374-83. Epub 2012 Jul 6.

School of Biological and Health Systems Engineering, Arizona State University, Tempe, Arizona, USA.

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http://dx.doi.org/10.1002/jbm.a.34266DOI Listing
December 2012

Novel sensory signaling systems in the kidney.

Curr Opin Nephrol Hypertens 2012 Jul;21(4):404-9

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1097/MNH.0b013e328354a6bdDOI Listing
July 2012

Jeannette Wilkins Award: Can locally delivered gadolinium be visualized on MRI? A pilot study.

Clin Orthop Relat Res 2012 Oct;470(10):2654-62

Center for Interventional Biomaterials, School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, USA.

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http://dx.doi.org/10.1007/s11999-012-2315-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442007PMC
October 2012

Are probiotics ready for prime time?

Authors:
Michael Caplan

JPEN J Parenter Enteral Nutr 2012 Jan;36(1 Suppl):6S

Pritzker School of Medicine, University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1177/0148607111423024DOI Listing
January 2012

The γ-secretase cleavage product of polycystin-1 regulates TCF and CHOP-mediated transcriptional activation through a p300-dependent mechanism.

Dev Cell 2012 Jan 15;22(1):197-210. Epub 2011 Dec 15.

Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06510, USA.

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http://dx.doi.org/10.1016/j.devcel.2011.10.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264829PMC
January 2012

Disseminated neuroendocrine carcinoma in a pediatric patient: a rare case and diagnostic challenge.

J Pediatr Hematol Oncol 2012 Apr;34(3):200-3

Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1097/MPH.0b013e3182288235DOI Listing
April 2012

Standardized methods to quantify thrombogenicity of blood-contacting materials via thromboelastography.

J Biomed Mater Res B Appl Biomater 2012 Jan 21;100(1):230-8. Epub 2011 Nov 21.

School of Biological and Health Systems Engineering, Arizona State University, Tempe, Arizona, USA.

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http://dx.doi.org/10.1002/jbm.b.31942DOI Listing
January 2012

Look who's talking. . . .

Authors:
Michael Caplan

Physiology (Bethesda) 2011 Oct;26(5):306

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http://dx.doi.org/10.1152/physiol.00031.2011DOI Listing
October 2011

Macrophages promote cyst growth in polycystic kidney disease.

J Am Soc Nephrol 2011 Oct 15;22(10):1809-14. Epub 2011 Sep 15.

Section of Nephrology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1681/ASN.2011010084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187181PMC
October 2011

Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.

Am J Physiol Renal Physiol 2011 Dec 17;301(6):F1346-57. Epub 2011 Aug 17.

Section of Pediatric Nephrology, Department of Pediatrics, Yale University School of Medicine, 333 Cedar St., New Haven, CT 06510, USA.

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http://dx.doi.org/10.1152/ajprenal.00420.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233870PMC
December 2011

Temporal differences in Erk1/2 activity distinguish among combinations of extracellular matrix components.

Acta Biomater 2011 Nov 14;7(11):3973-80. Epub 2011 Jul 14.

School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, USA.

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http://dx.doi.org/10.1016/j.actbio.2011.07.015DOI Listing
November 2011

Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases.

Proc Natl Acad Sci U S A 2011 Jun 13;108(26):10679-84. Epub 2011 Jun 13.

Department of Internal Medicine and Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1073/pnas.1016214108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127890PMC
June 2011

Gram negative bacteria are associated with the early stages of necrotizing enterocolitis.

PLoS One 2011 Mar 22;6(3):e18084. Epub 2011 Mar 22.

Department of Surgery, University of Chicago Medical Center, Chicago, Illinois, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062571PMC
March 2011

Regulated intramembrane proteolysis: signaling pathways and biological functions.

Physiology (Bethesda) 2011 Feb;26(1):34-44

Department of Medical Biochemistry and Biophysics, Division of Matrix Biology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1152/physiol.00028.2010DOI Listing
February 2011

Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis.

Proc Natl Acad Sci U S A 2011 Feb 24;108(6):2462-7. Epub 2011 Jan 24.

Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1073/pnas.1011498108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038735PMC
February 2011

Probiotics and prevention of neonatal necrotizing enterocolitis.

Curr Opin Pediatr 2011 Apr;23(2):151-5

Department of Pediatrics, NorthShore University Health System/Pritzker School of Medicine, University of Chicago, Evanston, Illinois 60201, USA.

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http://dx.doi.org/10.1097/MOP.0b013e328343d65fDOI Listing
April 2011

Polycystic kidney disease: pathogenesis and potential therapies.

Biochim Biophys Acta 2011 Oct 10;1812(10):1337-43. Epub 2010 Dec 10.

Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S092544391000269
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http://dx.doi.org/10.1016/j.bbadis.2010.11.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139769PMC
October 2011

The cell biology of polycystic kidney disease.

J Cell Biol 2010 Nov;191(4):701-10

Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1083/jcb.201006173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983067PMC
November 2010

Pyridoxine restores endothelial cell function in high glucose.

Metab Syndr Relat Disord 2011 Feb 30;9(1):63-8. Epub 2010 Oct 30.

School of Biological and Health Systems Engineering, Fulton Schools of Engineering, Arizona State University, Tempe, Arizona 85287-9709, USA.

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http://www.liebertpub.com/doi/10.1089/met.2010.0085
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http://dx.doi.org/10.1089/met.2010.0085DOI Listing
February 2011

Polycystin-1 surface localization is stimulated by polycystin-2 and cleavage at the G protein-coupled receptor proteolytic site.

Mol Biol Cell 2010 Dec 27;21(24):4338-48. Epub 2010 Oct 27.

Departments of Cell Biology and Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1091/mbc.E10-05-0407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002387PMC
December 2010

Inter-alpha inhibitor protein level in neonates predicts necrotizing enterocolitis.

J Pediatr 2010 Nov 17;157(5):757-61. Epub 2010 Jun 17.

Department of Pediatrics, Women & Infants Hospital, Brown Medical School, Providence, RI 02905, USA.

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http://dx.doi.org/10.1016/j.jpeds.2010.04.075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958175PMC
November 2010

AS160 associates with the Na+,K+-ATPase and mediates the adenosine monophosphate-stimulated protein kinase-dependent regulation of sodium pump surface expression.

Mol Biol Cell 2010 Dec 13;21(24):4400-8. Epub 2010 Oct 13.

Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520-8026, USA.

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http://www.molbiolcell.org/doi/10.1091/mbc.e10-06-0507
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http://dx.doi.org/10.1091/mbc.E10-06-0507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002392PMC
December 2010

MAL/VIP17, a new player in the regulation of NKCC2 in the kidney.

Mol Biol Cell 2010 Nov 22;21(22):3985-97. Epub 2010 Sep 22.

Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06511, USA.

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http://dx.doi.org/10.1091/mbc.E10-05-0456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982131PMC
November 2010