Michael C Mahaney

Michael C Mahaney

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Michael C Mahaney

Michael C Mahaney

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Analysis of serum changes in response to a high fat high cholesterol diet challenge reveals metabolic biomarkers of atherosclerosis.

PLoS One 2019 5;14(4):e0214487. Epub 2019 Apr 5.

Center for Precision Medicine, Department of Internal Medicine, Section of Molecular Medicine, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214487PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450610PMC
December 2019

Diet-induced leukocyte telomere shortening in a baboon model for early stage atherosclerosis.

Sci Rep 2019 Dec 12;9(1):19001. Epub 2019 Dec 12.

Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.

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http://dx.doi.org/10.1038/s41598-019-55348-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908639PMC
December 2019

Analysis of serum changes in response to a high fat high cholesterol diet challenge reveals metabolic biomarkers of atherosclerosis.

PLoS One 2019 5;14(4):e0214487. Epub 2019 Apr 5.

Center for Precision Medicine, Department of Internal Medicine, Section of Molecular Medicine, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214487PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450610PMC
December 2019

Diet-induced early-stage atherosclerosis in baboons: Lipoproteins, atherogenesis, and arterial compliance.

J Med Primatol 2018 02 16;47(1):3-17. Epub 2017 Jun 16.

South Texas Diabetes and Obesity Institute, School of Medicine, The University of Texas Rio Grande Valley, Brownsville, TX, USA.

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http://doi.wiley.com/10.1111/jmp.12283
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http://dx.doi.org/10.1111/jmp.12283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839476PMC
February 2018

The integration of quantitative genetics, paleontology, and neontology reveals genetic underpinnings of primate dental evolution.

Proc Natl Acad Sci U S A 2016 08 11;113(33):9262-7. Epub 2016 Jul 11.

South Texas Diabetes and Obesity Institute, School of Medicine, University of Texas Rio Grande Valley, Brownsville, TX 78520.

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http://dx.doi.org/10.1073/pnas.1605901113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995955PMC
August 2016

Cortical Folding of the Primate Brain: An Interdisciplinary Examination of the Genetic Architecture, Modularity, and Evolvability of a Significant Neurological Trait in Pedigreed Baboons (Genus Papio).

Genetics 2015 Jun 14;200(2):651-65. Epub 2015 Apr 14.

Department of Anatomy and Neurobiology, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63110 Department of Biology, Loyola University, Chicago, Illinois 60660.

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http://dx.doi.org/10.1534/genetics.114.173443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492386PMC
June 2015

Identification of candidate genes encoding an LDL-C QTL in baboons.

J Lipid Res 2013 Jul 17;54(7):1776-85. Epub 2013 Apr 17.

Department of Genetics, Texas Biomedical Research Institute , San Antonio, TX 78227, USA.

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http://dx.doi.org/10.1194/jlr.M032649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679381PMC
July 2013

A genome-wide linkage scan for quantitative trait loci influencing the craniofacial complex in humans (Homo sapiens sapiens).

Anat Rec (Hoboken) 2011 Apr 15;294(4):664-75. Epub 2011 Feb 15.

Lifespan Health Research Center, Dept. of Community Health, Boonshoft School of Medicine, Wright State University, 3171 Research Blvd., Kettering, OH 45420, USA.

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http://doi.wiley.com/10.1002/ar.21337
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http://dx.doi.org/10.1002/ar.21337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091483PMC
April 2011

Modularity in the mammalian dentition: mice and monkeys share a common dental genetic architecture.

J Exp Zool B Mol Dev Evol 2011 Jan;316(1):21-49

Human Evolution Research Center, University of California at Berkeley, Berkeley, California 94720, USA.

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http://dx.doi.org/10.1002/jez.b.21378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095220PMC
January 2011

Effects of diet on genetic regulation of lipoprotein metabolism in baboons.

Atherosclerosis 2010 Dec 28;213(2):499-504. Epub 2010 Sep 28.

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78245, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2010.08.079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997908PMC
December 2010

ABCB4 mediates diet-induced hypercholesterolemia in laboratory opossums.

J Lipid Res 2010 Oct 20;51(10):2922-8. Epub 2010 May 20.

Southwest National Primate Research Center, Southwest Foundation for Biomedical Research , San Antonio, TX, USA.

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http://dx.doi.org/10.1194/jlr.M005553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936762PMC
October 2010

The etiology of eruption disorders - further evidence of a 'genetic paradigm'

Semin Orthod 2010 Sep;16(3):180-185

Department of Orthodontics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, Tel: (919) 966-2762, ,

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http://dx.doi.org/10.1053/j.sodo.2010.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933797PMC
September 2010

Genetic regulation of endothelial inflammatory responses in baboons.

Arterioscler Thromb Vasc Biol 2010 Aug 27;30(8):1628-33. Epub 2010 May 27.

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX, USA.

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http://dx.doi.org/10.1161/ATVBAHA.110.205740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908371PMC
August 2010

Genetic integration of molar cusp size variation in baboons.

Am J Phys Anthropol 2010 Jun;142(2):246-60

Department of Integrative Biology, University of California Berkeley, Berkeley, CA 94720, USA.

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http://dx.doi.org/10.1002/ajpa.21221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914092PMC
June 2010

Cross-sectional geometry of the femoral midshaft in baboons is heritable.

Bone 2009 Nov 10;45(5):892-7. Epub 2009 Jun 10.

Department of Anthropology, Indiana University, Bloomington, IN 47408, USA.

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http://dx.doi.org/10.1016/j.bone.2009.05.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014089PMC
November 2009

Localization of multiple pleiotropic genes for lipoprotein metabolism in baboons.

J Lipid Res 2009 Jul 8;50(7):1420-8. Epub 2009 Mar 8.

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78245, USA.

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http://dx.doi.org/10.1194/jlr.M800583-JLR200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694340PMC
July 2009

LRP5 sequence and polymorphisms in the baboon.

J Med Primatol 2009 Apr;38(2):97-106

Department of Anthropology, Medical Sciences, Indiana University, Bloomington, IN 47405, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998286PMC
http://dx.doi.org/10.1111/j.1600-0684.2008.00317.xDOI Listing
April 2009

Quantitative Genetics, Pleiotropy, and Morphological Integration in the Dentition of Papio hamadryas.

Evol Biol 2009 Mar;36(1):5-18

Department of Integrative Biology, University of California, 3060 Valley Life Sciences Bldg, Berkeley 94720, CA, USA

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http://dx.doi.org/10.1007/s11692-008-9048-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423904PMC
March 2009

A genomewide linkage scan for quantitative trait loci influencing the craniofacial complex in baboons (Papio hamadryas spp.).

Genetics 2008 Sep 30;180(1):619-28. Epub 2008 Aug 30.

Lifespan Health Research Center, Department of Community Health, Boonshoft School of Medicine, Wright State University, Dayton, Ohio 45420, USA.

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http://dx.doi.org/10.1534/genetics.108.090407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2535711PMC
September 2008

Characterization of ghrelin in pedigreed baboons: evidence for heritability and pleiotropy.

Obesity (Silver Spring) 2008 Apr 31;16(4):804-10. Epub 2008 Jan 31.

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas, USA.

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http://dx.doi.org/10.1038/oby.2007.107DOI Listing
April 2008

Quantitative trait locus on Chromosome 19 for circulating levels of intercellular adhesion molecule-1 in Mexican Americans.

Atherosclerosis 2007 Dec 16;195(2):367-73. Epub 2006 Nov 16.

Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245-0549, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2006.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719976PMC
December 2007

Identification of promoter variants in baboon endothelial lipase that regulate high-density lipoprotein cholesterol levels.

Circulation 2007 Sep 20;116(10):1185-95. Epub 2007 Aug 20.

Department of Genetics, Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, 7620 NW Loop 410, San Antonio, TX 78227, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.107.704346DOI Listing
September 2007

Vitamin E dietary supplementation significantly affects multiple risk factors for cardiovascular disease in baboons.

Am J Clin Nutr 2007 Sep;86(3):597-603

Department of Genetics and the Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, San Antonio, TX 78245-0549, USA.

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http://dx.doi.org/10.1093/ajcn/86.3.597DOI Listing
September 2007

Effects of genes, sex, age, and activity on BMC, bone size, and areal and volumetric BMD.

J Bone Miner Res 2007 May;22(5):737-46

Southwest Foundation for Biomedical Research, San Antonio, TX, USA.

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http://dx.doi.org/10.1359/jbmr.070213DOI Listing
May 2007

Quantitative trait loci for peripheral blood cell counts: a study in baboons.

Mamm Genome 2007 May 8;18(5):361-72. Epub 2007 Jun 8.

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245-0549, USA.

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http://dx.doi.org/10.1007/s00335-007-9022-8DOI Listing
May 2007

Genetic correlations between mandibular molar cusp areas in baboons.

Am J Phys Anthropol 2007 Mar;132(3):445-54

Department of Integrative Biology, University of California at Berkeley, Berkeley, CA 94708, USA.

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http://dx.doi.org/10.1002/ajpa.20528DOI Listing
March 2007

A multivariate comparison of dental variation in wild and captive populations of baboons (Papio hamadryas).

Arch Oral Biol 2007 Feb 17;52(2):195-200. Epub 2006 Oct 17.

Department of Integrative Biology, University of California, 3060 Valley Life Sciences Building, Berkeley, CA 94720, USA.

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http://dx.doi.org/10.1016/j.archoralbio.2006.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691856PMC
February 2007

Sex-specific QTL effects on variation in paraoxonase 1 (PON1) activity in Mexican Americans.

Genet Epidemiol 2007 Jan;31(1):66-74

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78245-0549, USA.

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http://dx.doi.org/10.1002/gepi.20191DOI Listing
January 2007

QTL with pleiotropic effects on serum levels of bone-specific alkaline phosphatase and osteocalcin maps to the baboon ortholog of human chromosome 6p23-21.3.

J Bone Miner Res 2006 Dec;21(12):1888-96

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245-0549, USA.

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http://dx.doi.org/10.1359/jbmr.060812DOI Listing
December 2006

Evolution of genetically correlated traits: tooth size and body size in baboons.

Am J Phys Anthropol 2006 Nov;131(3):420-7

Department of Integrative Biology, University of California, Berkeley, California 94720, USA.

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http://dx.doi.org/10.1002/ajpa.20435DOI Listing
November 2006

A second-generation genetic linkage map of the baboon (Papio hamadryas) genome.

Genomics 2006 Sep 12;88(3):274-81. Epub 2006 May 12.

Department of Genetics and Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, 7620 NW Loop 410, San Antonio, TX 78227, USA.

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http://dx.doi.org/10.1016/j.ygeno.2006.03.020DOI Listing
September 2006

Multiple QTLs influence variation in paraoxonase 1 activity in Mexican Americans.

Hum Biol 2006 Jun;78(3):341-52

Department of Genetics, Southwest Foundation for Biomedical Research, PO Box 760549, San Antonio, TX 78245-0549, USA.

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http://dx.doi.org/10.1353/hub.2006.0050DOI Listing
June 2006

A comparison of univariate, bivariate, and trivariate whole-genome linkage screens of genetically correlated electrophysiological endophenotypes.

BMC Genet 2005 Dec 30;6 Suppl 1:S117. Epub 2005 Dec 30.

Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, Texas 78245-0549, USA.

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http://bmcgenet.biomedcentral.com/articles/10.1186/1471-2156
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http://dx.doi.org/10.1186/1471-2156-6-S1-S117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866821PMC
December 2005

X chromosome effects and their interactions with mitochondrial effects.

BMC Genet 2005 Dec 30;6 Suppl 1:S157. Epub 2005 Dec 30.

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78245, USA.

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http://dx.doi.org/10.1186/1471-2156-6-S1-S157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866777PMC
December 2005

Mitochondrial genetic effects on latent class variables associated with susceptibility to alcoholism.

BMC Genet 2005 Dec 30;6 Suppl 1:S158. Epub 2005 Dec 30.

Youngstown State University, Department of Sociology & Anthropology, One University Plaza, Youngstown, OH 44555, USA.

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http://dx.doi.org/10.1186/1471-2156-6-S1-S158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866776PMC
December 2005

Genetic influences on peripheral blood cell counts: a study in baboons.

Blood 2005 Aug 3;106(4):1210-4. Epub 2005 May 3.

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX, USA.

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http://dx.doi.org/10.1182/blood-2004-12-4863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895191PMC
August 2005

Determinants of variation in serum paraoxonase enzyme activity in baboons.

J Lipid Res 2005 Jul 16;46(7):1450-6. Epub 2005 Apr 16.

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78245, USA.

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http://dx.doi.org/10.1194/jlr.M400473-JLR200DOI Listing
July 2005

Joint linkage and association analysis of the hepatic lipase promoter polymorphism and lipoprotein size phenotypes.

Hum Biol 2005 Feb;77(1):17-25

Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245-0549, USA.

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http://dx.doi.org/10.1353/hub.2005.0025DOI Listing
February 2005

Gene by smoking interaction: evidence for effects on low-density lipoprotein size and plasma levels of triglyceride and high-density lipoprotein cholesterol.

Hum Biol 2004 Dec;76(6):863-76

Lifespan Health Research Center, Department of Community Health, Wright State University School of Medicine, 3171 Research Blvd., Kettering, OH 45420-4014, USA.

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http://dx.doi.org/10.1353/hub.2005.0014DOI Listing
December 2004

Intercellular adhesion molecule-1 concentration is genetically correlated with insulin resistance, obesity, and HDL concentration in Mexican Americans.

Diabetes 2004 Oct;53(10):2691-5

Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245-0549, USA.

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http://dx.doi.org/10.2337/diabetes.53.10.2691DOI Listing
October 2004

Quantitative genetic analysis of glucose transporter 4 mRNA levels in baboon adipose.

Obes Res 2004 Oct;12(10):1652-7

Department of Genetics, Southwest Foundation for Biomedical Research, 7620 NW Loop 410, San Antonio, TX 78227-5301, USA.

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http://dx.doi.org/10.1038/oby.2004.205DOI Listing
October 2004

Cosupplementation with vitamin E and coenzyme Q10 reduces circulating markers of inflammation in baboons.

Am J Clin Nutr 2004 Sep;80(3):649-55

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356523PMC
http://dx.doi.org/10.1093/ajcn/80.3.649DOI Listing
September 2004

Genetics and the evolution of primate enamel thickness: a baboon model.

Am J Phys Anthropol 2004 Jul;124(3):223-33

Department of Anthropology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

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http://dx.doi.org/10.1002/ajpa.10353DOI Listing
July 2004

Statistical genetics of molar cusp patterning in pedigreed baboons: implications for primate dental development and evolution.

J Exp Zool B Mol Dev Evol 2004 May;302(3):268-83

Department of Anthropology, University of Illinois, Urbana, Illinois 61801,USA.

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http://dx.doi.org/10.1002/jez.b.21DOI Listing
May 2004

Genome-wide scan for quantitative trait loci influencing LDL size and plasma triglyceride in familial hypertriglyceridemia.

J Lipid Res 2003 Nov 16;44(11):2161-8. Epub 2003 Aug 16.

Department of Epidemiology and Institute for Public Health Genetics, School of Public Health and Community Medicine, University of Washington, Seattle, WA, USA.

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http://www.jlr.org/lookup/doi/10.1194/jlr.M300272-JLR200
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http://dx.doi.org/10.1194/jlr.M300272-JLR200DOI Listing
November 2003

Genetic contributions to expression of the baboon cingular remnant.

Arch Oral Biol 2003 Sep;48(9):663-72

Department of Anthropology, University of Illinois at Urbana-Champaign, 109 Davenport Hall, MC-148, Urbana, IL 61801, USA.

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http://dx.doi.org/10.1016/s0003-9969(03)00132-8DOI Listing
September 2003

Localization of genes that control LDL size fractions in baboons.

Atherosclerosis 2003 May;168(1):15-22

Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245-0549, USA.

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http://dx.doi.org/10.1016/s0021-9150(03)00051-0DOI Listing
May 2003

Two loci affect angiotensin I-converting enzyme activity in baboons.

Hypertension 2003 Mar 2;41(3 Pt 2):854-9. Epub 2002 Dec 2.

Department of Human Genetics, University of Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1161/01.HYP.0000046280.16849.BFDOI Listing
March 2003

The baboon as a nonhuman primate model for the study of the genetics of obesity.

Obes Res 2003 Jan;11(1):75-80

Department of Genetics, Southwest Regional Primate Research Center, San Antonio, Texas 78245-0549, USA.

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http://dx.doi.org/10.1038/oby.2003.12DOI Listing
January 2003

Locus controlling LDL cholesterol response to dietary cholesterol is on baboon homologue of human chromosome 6.

Arterioscler Thromb Vasc Biol 2002 Oct;22(10):1720-5

Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pa 15261, USA.

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http://dx.doi.org/10.1161/01.atv.0000032133.12377.4dDOI Listing
October 2002

Lifespan in captive baboons is heritable.

Mech Ageing Dev 2002 Sep;123(11):1461-7

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78245-0549, USA.

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http://dx.doi.org/10.1016/s0047-6374(02)00083-0DOI Listing
September 2002

A major gene influences variation in large HDL particles and their response to diet in baboons.

Atherosclerosis 2002 Aug;163(2):241-8

Department of Genetics, Southwest Foundation for Biomedical Research, PO Box 760549, San Antonio, TX 78245-0549, USA.

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http://dx.doi.org/10.1016/s0021-9150(02)00015-1DOI Listing
August 2002

Genetic determination of HDL variation and response to diet in baboons.

Atherosclerosis 2002 Apr;161(2):335-43

Department of Genetics, Southwest Foundation for Biomedical Research, PO Box 760549, San Antonio, TX 78245-0549, USA.

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http://dx.doi.org/10.1016/s0021-9150(01)00658-xDOI Listing
April 2002

Genotype by smoking interaction for leptin levels in the San Antonio Family Heart Study.

Genet Epidemiol 2002 Feb;22(2):105-15

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245-0549, USA.

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http://dx.doi.org/10.1002/gepi.0135DOI Listing
February 2002

Statistical genetic comparison of two techniques for assessing molar crown size in pedigreed baboons.

Am J Phys Anthropol 2002 Feb;117(2):182-9

Department of Anthropology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

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http://dx.doi.org/10.1002/ajpa.10022DOI Listing
February 2002

Linkage of high-density lipoprotein-cholesterol concentrations to a locus on chromosome 9p in Mexican Americans.

Nat Genet 2002 Jan 17;30(1):102-5. Epub 2001 Dec 17.

Division of Clinical Epidemiology, Department of Medicine, University of Texas Health Science Center, San Antonio, Texas, USA.

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http://www.nature.com/doifinder/10.1038/ng810
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http://dx.doi.org/10.1038/ng810DOI Listing
January 2002

Leptin's sexual dimorphism results from genotype by sex interactions mediated by testosterone.

Obes Res 2002 Jan;10(1):14-21

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245-0549, USA.

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http://dx.doi.org/10.1038/oby.2002.3DOI Listing
January 2002

Statistical Modeling Approaches to Genetic Analysis.

ILAR J 1997 ;38(2):76-82

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas, USA.

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http://dx.doi.org/10.1093/ilar.38.2.76DOI Listing
January 1997

Quantitative genetics of sexual dimorphism in body fat measurements.

Am J Hum Biol 1993 ;5(6):725-734

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78228.

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http://dx.doi.org/10.1002/ajhb.1310050616DOI Listing
January 1993