Michael C Bassik

Michael C Bassik

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Michael C Bassik

Michael C Bassik

Publications by authors named "Michael C Bassik"

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Astrocyte-to-astrocyte contact and a positive feedback loop of growth factor signaling regulate astrocyte maturation.

Glia 2019 08 29;67(8):1571-1597. Epub 2019 Apr 29.

Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at the University of California, Los Angeles, California.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/glia.23630
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http://dx.doi.org/10.1002/glia.23630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557696PMC
August 2019

Neuronally Enriched RUFY3 Is Required for Caspase-Mediated Axon Degeneration.

Neuron 2019 Aug 17;103(3):412-422.e4. Epub 2019 Jun 17.

Department of Biology, Stanford University, Stanford, CA, USA; Laboratory of Brain Development and Repair, The Rockefeller University, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.05.030DOI Listing
August 2019

Discovery of small molecule inhibitors of human uridine-cytidine kinase 2 by high-throughput screening.

Bioorg Med Chem Lett 2019 Aug 7. Epub 2019 Aug 7.

Department of Chemistry, Stanford University, Stanford, CA 94305, USA; Stanford ChEM-H, Stanford, CA 94305, USA; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2019.08.010DOI Listing
August 2019

SLC19A1 Is an Importer of the Immunotransmitter cGAMP.

Mol Cell 2019 Jul 21;75(2):372-381.e5. Epub 2019 May 21.

Department of Biochemistry, Stanford University, Stanford, CA 94305, USA; Program in Chemistry, Engineering, and Medicine for Human Health (ChEM-H), Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.05.006DOI Listing
July 2019

Discovery of common and rare genetic risk variants for colorectal cancer.

Authors:
Jeroen R Huyghe Stephanie A Bien Tabitha A Harrison Hyun Min Kang Sai Chen Stephanie L Schmit David V Conti Conghui Qu Jihyoun Jeon Christopher K Edlund Peyton Greenside Michael Wainberg Fredrick R Schumacher Joshua D Smith David M Levine Sarah C Nelson Nasa A Sinnott-Armstrong Demetrius Albanes M Henar Alonso Kristin Anderson Coral Arnau-Collell Volker Arndt Christina Bamia Barbara L Banbury John A Baron Sonja I Berndt Stéphane Bézieau D Timothy Bishop Juergen Boehm Heiner Boeing Hermann Brenner Stefanie Brezina Stephan Buch Daniel D Buchanan Andrea Burnett-Hartman Katja Butterbach Bette J Caan Peter T Campbell Christopher S Carlson Sergi Castellví-Bel Andrew T Chan Jenny Chang-Claude Stephen J Chanock Maria-Dolores Chirlaque Sang Hee Cho Charles M Connolly Amanda J Cross Katarina Cuk Keith R Curtis Albert de la Chapelle Kimberly F Doheny David Duggan Douglas F Easton Sjoerd G Elias Faye Elliott Dallas R English Edith J M Feskens Jane C Figueiredo Rocky Fischer Liesel M FitzGerald David Forman Manish Gala Steven Gallinger W James Gauderman Graham G Giles Elizabeth Gillanders Jian Gong Phyllis J Goodman William M Grady John S Grove Andrea Gsur Marc J Gunter Robert W Haile Jochen Hampe Heather Hampel Sophia Harlid Richard B Hayes Philipp Hofer Michael Hoffmeister John L Hopper Wan-Ling Hsu Wen-Yi Huang Thomas J Hudson David J Hunter Gemma Ibañez-Sanz Gregory E Idos Roxann Ingersoll Rebecca D Jackson Eric J Jacobs Mark A Jenkins Amit D Joshi Corinne E Joshu Temitope O Keku Timothy J Key Hyeong Rok Kim Emiko Kobayashi Laurence N Kolonel Charles Kooperberg Tilman Kühn Sébastien Küry Sun-Seog Kweon Susanna C Larsson Cecelia A Laurie Loic Le Marchand Suzanne M Leal Soo Chin Lee Flavio Lejbkowicz Mathieu Lemire Christopher I Li Li Li Wolfgang Lieb Yi Lin Annika Lindblom Noralane M Lindor Hua Ling Tin L Louie Satu Männistö Sanford D Markowitz Vicente Martín Giovanna Masala Caroline E McNeil Marilena Melas Roger L Milne Lorena Moreno Neil Murphy Robin Myte Alessio Naccarati Polly A Newcomb Kenneth Offit Shuji Ogino N Charlotte Onland-Moret Barbara Pardini Patrick S Parfrey Rachel Pearlman Vittorio Perduca Paul D P Pharoah Mila Pinchev Elizabeth A Platz Ross L Prentice Elizabeth Pugh Leon Raskin Gad Rennert Hedy S Rennert Elio Riboli Miguel Rodríguez-Barranco Jane Romm Lori C Sakoda Clemens Schafmayer Robert E Schoen Daniela Seminara Mitul Shah Tameka Shelford Min-Ho Shin Katerina Shulman Sabina Sieri Martha L Slattery Melissa C Southey Zsofia K Stadler Christa Stegmaier Yu-Ru Su Catherine M Tangen Stephen N Thibodeau Duncan C Thomas Sushma S Thomas Amanda E Toland Antonia Trichopoulou Cornelia M Ulrich David J Van Den Berg Franzel J B van Duijnhoven Bethany Van Guelpen Henk van Kranen Joseph Vijai Kala Visvanathan Pavel Vodicka Ludmila Vodickova Veronika Vymetalkova Korbinian Weigl Stephanie J Weinstein Emily White Aung Ko Win C Roland Wolf Alicja Wolk Michael O Woods Anna H Wu Syed H Zaidi Brent W Zanke Qing Zhang Wei Zheng Peter C Scacheri John D Potter Michael C Bassik Anshul Kundaje Graham Casey Victor Moreno Goncalo R Abecasis Deborah A Nickerson Stephen B Gruber Li Hsu Ulrike Peters

Nat Genet 2019 01 3;51(1):76-87. Epub 2018 Dec 3.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://www.nature.com/articles/s41588-018-0286-6
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http://dx.doi.org/10.1038/s41588-018-0286-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358437PMC
January 2019

Genome-wide CRISPR Analysis Identifies Substrate-Specific Conjugation Modules in ER-Associated Degradation.

Mol Cell 2019 01 20;73(2):377-389.e11. Epub 2018 Dec 20.

Department of Biology, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.11.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338494PMC
January 2019

Genome-wide interrogation of extracellular vesicle biology using barcoded miRNAs.

Elife 2018 12 17;7. Epub 2018 Dec 17.

Department of Biochemistry, Stanford University School of Medicine, Stanford, United States.

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https://elifesciences.org/articles/41460
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http://dx.doi.org/10.7554/eLife.41460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312402PMC
December 2018

KIF15 nanomechanics and kinesin inhibitors, with implications for cancer chemotherapeutics.

Proc Natl Acad Sci U S A 2018 05 27;115(20):E4613-E4622. Epub 2018 Apr 27.

Department of Biology, Stanford University, Stanford, CA 94305;

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http://dx.doi.org/10.1073/pnas.1801242115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960320PMC
May 2018

Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators.

Nature 2018 01 6;553(7687):228-232. Epub 2017 Dec 6.

Department of Chemical and Systems Biology, Stanford School of Medicine, Stanford University, Stanford, California 94305, USA.

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http://www.nature.com/doifinder/10.1038/nature25179
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http://dx.doi.org/10.1038/nature25179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774979PMC
January 2018

Human pyrimidine nucleotide biosynthesis as a target for antiviral chemotherapy.

Curr Opin Biotechnol 2017 12 27;48:127-134. Epub 2017 Apr 27.

Departments of Chemistry, Genetics, and Chemical Engineering, and Stanford ChEM-H, Stanford University, Stanford, CA 94305, United States. Electronic address:

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http://dx.doi.org/10.1016/j.copbio.2017.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659961PMC
December 2017

Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes.

Mol Cell 2017 Oct;68(1):26-43

Department of Genetics and Stanford University Chemistry, Engineering, and Medicine for Human Health (ChEM-H), Stanford, CA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10972765173070
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http://dx.doi.org/10.1016/j.molcel.2017.09.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997582PMC
October 2017

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

Nat Biotechnol 2017 05 20;35(5):463-474. Epub 2017 Mar 20.

Department of Genetics, Stanford University, Stanford, California, USA.

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http://www.nature.com/doifinder/10.1038/nbt.3834
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http://dx.doi.org/10.1038/nbt.3834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557292PMC
May 2017

Finding host targets for HIV therapy.

Nat Genet 2017 Jan;49(2):175-176

Departments of Genetics and Chemistry, Engineering and Medicine for Human Health (ChEM-H), Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1038/ng.3777DOI Listing
January 2017

The mTOR Complex Controls HIV Latency.

Cell Host Microbe 2016 Dec;20(6):785-797

Gladstone Institute of Virology and Immunology, Gladstone Institutes, San Francisco, CA 94158, USA; Department of Medicine, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2016.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354304PMC
December 2016

Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes.

Nat Biotechnol 2016 Jun 9;34(6):634-6. Epub 2016 May 9.

Department of Genetics, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1038/nbt.3567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900911PMC
June 2016

Next-generation libraries for robust RNA interference-based genome-wide screens.

Proc Natl Acad Sci U S A 2015 Jun 15;112(26):E3384-91. Epub 2015 Jun 15.

Department of Cellular and Molecular Pharmacology, California Institute for Quantitative Biomedical Research, University of California, San Francisco, CA 94158; Howard Hughes Medical Institute, University of California, San Francisco, CA 94158;

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http://dx.doi.org/10.1073/pnas.1508821112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491794PMC
June 2015

Unraveling the mechanism of cell death induced by chemical fibrils.

Nat Chem Biol 2014 Nov 28;10(11):969-76. Epub 2014 Sep 28.

1] Department of Pharmaceutical Chemistry, University of California-San Francisco, San Francisco, California, USA. [2] Department of Cellular and Molecular Pharmacology, University of California-San Francisco, San Francisco, California, USA.

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http://www.nature.com/articles/nchembio.1639
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http://dx.doi.org/10.1038/nchembio.1639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201873PMC
November 2014

Weak base pairing in both seed and 3' regions reduces RNAi off-targets and enhances si/shRNA designs.

Nucleic Acids Res 2014 Oct 30;42(19):12169-76. Epub 2014 Sep 30.

Departments of Pediatrics and Genetics, Stanford University, Stanford, CA 94305, USA

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http://dx.doi.org/10.1093/nar/gku854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231738PMC
October 2014

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation.

Cell 2014 Oct 9;159(3):647-61. Epub 2014 Oct 9.

Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94158, USA; California Institute for Quantitative Biomedical Research, San Francisco, CA 94158, USA; Center for RNA Systems Biology, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.09.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253859PMC
October 2014

Functional genomics platform for pooled screening and generation of mammalian genetic interaction maps.

Nat Protoc 2014 Aug 3;9(8):1825-47. Epub 2014 Jul 3.

1] Department of Cellular and Molecular Pharmacology, California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, California, USA. [2] Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nprot.2014.103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144868PMC
August 2014

Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells.

Proc Natl Acad Sci U S A 2013 Jun 5;110(25):E2317-26. Epub 2013 Jun 5.

Department of Cellular and Molecular Pharmacology, California Institute for Quantitative Biomedical Research, University of California, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1073/pnas.1307002110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690882PMC
June 2013

A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility.

Cell 2013 Feb 8;152(4):909-22. Epub 2013 Feb 8.

Department of Cellular and Molecular Pharmacology, California Institute for Quantitative Biomedical Research and Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94122, USA.

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http://dx.doi.org/10.1016/j.cell.2013.01.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652613PMC
February 2013

Knocking out the door to tunicamycin entry.

Proc Natl Acad Sci U S A 2011 Jul 6;108(29):11731-2. Epub 2011 Jul 6.

Department of Cellular and Molecular Pharmacology, Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1073/pnas.1109035108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141928PMC
July 2011

Rapid creation and quantitative monitoring of high coverage shRNA libraries.

Nat Methods 2009 Jun 17;6(6):443-5. Epub 2009 May 17.

Department of Cellular and Molecular Pharmacology, California Institute for Quantitative Biomedical Research, Howard Hughes Medical Institute, University of California, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nmeth.1330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783737PMC
June 2009

PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum.

J Biol Chem 2006 Aug 22;281(32):23003-12. Epub 2006 May 22.

Howard Hughes Medical Institute, Department of Cancer Immunology and AIDS, Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M602648200
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http://dx.doi.org/10.1074/jbc.M602648200DOI Listing
August 2006

The control of endoplasmic reticulum-initiated apoptosis by the BCL-2 family of proteins.

Curr Mol Med 2006 Feb;6(1):99-109

Department of Pathology, University of California, San Francisco, 94143, USA.

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February 2006

Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum.

Proc Natl Acad Sci U S A 2005 Jan 21;102(1):105-10. Epub 2004 Dec 21.

Howard Hughes Medical Institute, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Departments of Pathology and Medicine, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.0408352102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC544078PMC
January 2005

Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis.

EMBO J 2004 Mar 4;23(5):1207-16. Epub 2004 Mar 4.

Department of Pathology and Medicine, Howard Hughes Medical Institute, Dana Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1038/sj.emboj.7600104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC380968PMC
March 2004

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics.

Cancer Cell 2002 Sep;2(3):183-92

Howard Hughes Medical Institute, Department of Pathology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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September 2002