Michael Berndt

Michael Berndt

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Michael Berndt

Michael Berndt

Publications by authors named "Michael Berndt"

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100Publications

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The Role of Platelet-Derived ADP and ATP in Promoting Pancreatic Cancer Cell Survival and Gemcitabine Resistance.

Cancers (Basel) 2017 Oct 24;9(10). Epub 2017 Oct 24.

Platelet Research Laboratory, Curtin Health and Innovation Research Institute, Faculty of Health Sciences, Curtin University, Bentley, WA 6102, Australia.

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October 2017

Targeting Platelets for the Treatment of Cancer.

Cancers (Basel) 2017 Jul 22;9(7). Epub 2017 Jul 22.

Faculty of Health Sciences, Curtin University, Perth 6100, Australia.

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July 2017

Influence of porewater sulfide on methylmercury production and partitioning in sulfate-impacted lake sediments.

Sci Total Environ 2017 Feb 23;580:1197-1204. Epub 2016 Dec 23.

Water Resources Science Program, University of Minnesota, United States; Department of Civil Engineering, University of Minnesota Duluth, United States. Electronic address:

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February 2017

A comparison of results from a hydrologic transport model (HSPF) with distributions of sulfate and mercury in a mine-impacted watershed in northeastern Minnesota.

J Environ Manage 2016 Oct 17;181:74-79. Epub 2016 Jun 17.

Minnesota Pollution Control Agency, 520 Lafayette Road, St. Paul, MN, 55155, USA.

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October 2016

Isotope independent determination of PET/CT modulation transfer functions from phantom measurements on spheres.

Med Phys 2016 Oct;43(10):5767

Department of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, Switzerland.

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October 2016

Platelet clearance via shear-induced unfolding of a membrane mechanoreceptor.

Nat Commun 2016 Sep 27;7:12863. Epub 2016 Sep 27.

Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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September 2016

Liver-mediated shedding of platelet GPVI.

Blood 2016 08;128(6):751-2

MONASH UNIVERSITY.

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August 2016

Methylmercury production in a chronically sulfate-impacted sub-boreal wetland.

Environ Sci Process Impacts 2016 Jun 25;18(6):725-34. Epub 2016 May 25.

Department of Civil Engineering, University of Minnesota Duluth, USA.

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June 2016

The functional role of platelets in the regulation of angiogenesis.

Platelets 2015 15;26(3):199-211. Epub 2014 May 15.

School of Physiology and Pharmacology, University of Bristol , Bristol , UK and.

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December 2015

Role of focal adhesion tyrosine kinases in GPVI-dependent platelet activation and reactive oxygen species formation.

PLoS One 2014 21;9(11):e113679. Epub 2014 Nov 21.

Department of Experimental Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland; Curtin Health Innovation Research Institute, Faculty of Health Sciences, Curtin University, Perth, Australia.

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December 2015

Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα.

Redox Biol 2015 Dec 28;6:640-7. Epub 2015 Oct 28.

Department of Experimental Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland; Faculty of Health Sciences, Curtin University, Perth, Australia; Curtin Health Innovation Research Institute, Curtin University, Perth, Australia. Electronic address:

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December 2015

COMP: an endogenous thrombin inhibitor.

Blood 2015 Aug;126(7):831-2

CURTIN UNIVERSITY.

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August 2015

Current state and novel approaches of antiplatelet therapy.

Arterioscler Thromb Vasc Biol 2015 Jun 2;35(6):1327-38. Epub 2015 Apr 2.

From the Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia (P.M., M.C.B); Western Australian Centre for Thrombosis and Haemostasis, Murdoch University, Perth, Western Australia, Australia (R.I.B.); and Australian Centre for Blood Diseases, Department of Clinical Haematology, Monash University, Melbourne, Victoria, Australia (R.K.A.).

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June 2015

Control and gating of kinesin-microtubule motility on electrically heated thermo-chips.

Biomed Microdevices 2014 Jun;16(3):459-63

Department of Electrical Engineering and Electronics, University of Liverpool, Brownlow Hill, Liverpool, L69 3GJ, UK.

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June 2014

Bernard-Soulier syndrome: an update.

Semin Thromb Hemost 2013 Sep 8;39(6):656-62. Epub 2013 Aug 8.

Department of Clinical Haematology, Monash University, Systems Haematology Laboratory, Australian Centre for Blood Diseases, Melbourne, Australia.

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September 2013

LIM kinase-1 selectively promotes glycoprotein Ib-IX-mediated TXA2 synthesis, platelet activation, and thrombosis.

Blood 2013 May 25;121(22):4586-94. Epub 2013 Apr 25.

Department of Pharmacology, University of Illinois at Chicago College of Medicine, Chicago, IL 60612, USA.

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May 2013

Using a quartz paraboloid for versatile wide-field TIR microscopy with sub-nanometer localization accuracy.

Opt Express 2013 Feb;21(3):3523-39

Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany.

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February 2013

An acquired defect associated with abnormal signaling of the platelet collagen receptor glycoprotein VI.

Acta Haematol 2012 24;128(4):233-41. Epub 2012 Aug 24.

Australian Centre for Blood Diseases, Monash University, Melbourne, Vic., Australia.

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January 2013

The role of Rac1 in glycoprotein Ib-IX-mediated signal transduction and integrin activation.

Arterioscler Thromb Vasc Biol 2012 Nov 20;32(11):2761-8. Epub 2012 Sep 20.

Department of Pharmacology, University of Illinois College of Medicine, 835 South Wolcott Ave, Chicago, IL 60612, USA.

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November 2012

Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function.

Sci Signal 2012 Oct 30;5(248):ra78. Epub 2012 Oct 30.

Centre of Cardiovascular Sciences, Institute of Biomedical Research, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.

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October 2012

Cadherin 6 has a functional role in platelet aggregation and thrombus formation.

Arterioscler Thromb Vasc Biol 2012 Jul 26;32(7):1724-31. Epub 2012 Apr 26.

Royal College of Surgeons in Ireland, Dublin, Ireland.

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July 2012

Platelet receptor shedding.

Methods Mol Biol 2012 ;788:321-39

Australian Centre for Blood Diseases, Monash University, Melbourne, VIC, Australia.

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April 2012

Methylmercury and dissolved organic carbon relationships in a wetland-rich watershed impacted by elevated sulfate from mining.

Environ Pollut 2012 Feb 25;161:321-7. Epub 2011 Jun 25.

Minnesota Department of Natural Resources, Division of Lands and Minerals, 500 Lafayette Road, St. Paul, MN 55155-4045, USA.

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February 2012

Coagulation-induced shedding of platelet glycoprotein VI mediated by factor Xa.

Blood 2011 Apr 20;117(14):3912-20. Epub 2011 Jan 20.

Australian Centre for Blood Diseases, Monash University, Alfred Medical Research and Education Precinct, Commercial Road, Melbourne, Australia.

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April 2011

High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIbα-filamin interaction.

Blood 2011 Mar 14;117(9):2718-27. Epub 2010 Dec 14.

Australian Centre for Blood Diseases, Monash University, Alfred Medical Research & Education Precinct, Melbourne, Victoria 3004, Australia.

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March 2011

Bernard-Soulier syndrome.

Haematologica 2011 Mar;96(3):355-9

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March 2011

Thrombotic thrombocytopenic purpura: reducing the risk?

J Clin Invest 2011 Feb 25;121(2):522-4. Epub 2011 Jan 25.

Biomedical Diagnostics Institute, Dublin City University, and Royal College of Surgeons in Ireland, Dublin, Ireland.

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February 2011

An event of shear importance.

Blood 2011 Jan;117(1):5-7

Monash University.

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January 2011

Transmembrane and trans-subunit regulation of ectodomain shedding of platelet glycoprotein Ibalpha.

J Biol Chem 2010 Oct 17;285(42):32096-104. Epub 2010 Aug 17.

Department of Biochemistry and Molecular Biology, Center for Membrane Biology, University of Texas Health Science Center, Houston, Texas 77030, USA.

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October 2010

Arterial thrombosis: going, gone!

Blood 2010 Sep;116(13):2201-2

Monash University and Dublin City University.

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September 2010

Nerve growth factor inhibits metalloproteinase-disintegrins and blocks ectodomain shedding of platelet glycoprotein VI.

J Biol Chem 2010 Apr 17;285(16):11793-9. Epub 2010 Feb 17.

Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3004, Australia.

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April 2010

Axial nanometer distances measured by fluorescence lifetime imaging microscopy.

Nano Lett 2010 Apr;10(4):1497-500

Max-Planck-Institute of Molecular Cell Biology and Genetics, Dresden, Germany.

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April 2010

Measuring soluble platelet glycoprotein VI in human plasma by ELISA.

Platelets 2009 May;20(3):143-9

Department of Immunology, Monash University, Alfred Medical Research & Education Precinct, Melbourne, Australia.

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May 2009

Systems biology meets platelet biology.

Blood 2008 Nov;112(10):3920-1

University College Cork.

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November 2008

The origins of public concern with taconite and human health: Reserve Mining and the asbestos case.

Regul Toxicol Pharmacol 2008 Oct 22;52(1 Suppl):S31-9. Epub 2007 Oct 22.

Minnesota Department of Natural Resources, Division of Lands and Minerals, 500 Lafayette Road, St. Paul, MN 55155, USA.

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October 2008

Platelet adhesion: a game of catch and release.

J Clin Invest 2008 Sep;118(9):3009-11

Department of Immunology, Alfred Medical Research & Education Precinct (AMREP), Monash University, Melbourne, Victoria, Australia.

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September 2008

Microparticles facilitate neutrophil/platelet crosstalk.

Blood 2008 Sep;112(6):2174-5

Monash University.

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September 2008

Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway.

Blood 2008 Aug 11;112(4):1139-46. Epub 2008 Jun 11.

Department of Pharmacology, University of Illinois at Chicago, Chicago, IL 60612, USA.

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August 2008

Antihemostatic activity of human granzyme B mediated by cleavage of von Willebrand factor.

J Biol Chem 2008 Aug 24;283(33):22498-504. Epub 2008 Jun 24.

Department of Biochemistry and Molecular Biology, Monash University, Clayton 3800, Victoria, Australia.

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August 2008

New direction for WE thrombin.

Arterioscler Thromb Vasc Biol 2008 Feb;28(2):205-7

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February 2008

Platelet receptor redox regulation.

Platelets 2008 Feb;19(1):1-8

Department of Immunology, Monash University, Alfred Medical Research & Education Precinct, Melbourne 3004, Victoria, Australia.

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February 2008

Fractionation of snake venom metalloproteinases by metal ion affinity: a purified cobra metalloproteinase, Nk, from Naja kaouthia binds Ni2+-agarose.

Toxicon 2007 Dec 28;50(8):1064-72. Epub 2007 Jul 28.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, 3008 Victoria, Australia.

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December 2007

Snake venom metalloproteinases, crotarhagin and alborhagin, induce ectodomain shedding of the platelet collagen receptor, glycoprotein VI.

Thromb Haemost 2007 Dec;98(6):1285-90

Department of Biochemistry and Molecular Biology, Monash University, Alfred Medical Research & Education Precinct, Melbourne, Victoria, Australia.

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December 2007

Ligand binding rapidly induces disulfide-dependent dimerization of glycoprotein VI on the platelet plasma membrane.

J Biol Chem 2007 Oct 9;282(42):30434-41. Epub 2007 Aug 9.

Department of Immunology, Monash University, Melbourne 3004, Australia.

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October 2007

Platelet receptor proteolysis: a mechanism for downregulating platelet reactivity.

Arterioscler Thromb Vasc Biol 2007 Jul 26;27(7):1511-20. Epub 2007 Apr 26.

Department of Immunology, Monash University, Alfred Medical Research & Education Precinct, Melbourne 3004, Australia.

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July 2007

The 14-3-3zeta-GPIb-IX-V complex as an antiplatelet target.

Drug News Perspect 2007 Jun;20(5):285-92

Department of Immunology, Monash University, Melbourne, Australia.

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June 2007

Bruton tyrosine kinase is essential for botrocetin/VWF-induced signaling and GPIb-dependent thrombus formation in vivo.

Blood 2006 Oct 20;108(8):2596-603. Epub 2006 Jun 20.

Department of Biology, University of Memphis, Memphis, TN 38152, USA.

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October 2006

Evidence for activation of tissue factor by an allosteric disulfide bond.

Biochemistry 2006 Oct;45(39):12020-8

Centre for Vascular Research, University of New South Wales, Sydney, NSW 2052, Australia.

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October 2006

Leucine-rich repeats 2-4 (Leu60-Glu128) of platelet glycoprotein Ibalpha regulate shear-dependent cell adhesion to von Willebrand factor.

J Biol Chem 2006 Sep 14;281(36):26419-23. Epub 2006 Jun 14.

Department of Immunology and the Department of Biochemistry and Molecular Biology, Monash University, Victoria, 3800, Australia.

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September 2006

Transforming growth factor beta suppresses human telomerase reverse transcriptase (hTERT) by Smad3 interactions with c-Myc and the hTERT gene.

J Biol Chem 2006 Sep 19;281(35):25588-600. Epub 2006 Jun 19.

Department of Immunology and Monash Institute of Medical Research, Monash University, Melbourne, Victoria 3181, Australia.

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September 2006

Calmodulin interacts with the platelet ADP receptor P2Y1.

Biochem J 2006 Sep;398(3):339-43

Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.

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September 2006

Activation-independent, antibody-mediated removal of GPVI from circulating human platelets: development of a novel NOD/SCID mouse model to evaluate the in vivo effectiveness of anti-human platelet agents.

Blood 2006 Aug 28;108(3):908-14. Epub 2006 Mar 28.

Blood Research Institute, BloodCenter of Wisconsin, PO Box 2178, 638 N 18th St, Milwaukee, 53201, USA.

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August 2006

The cryptome: a subset of the proteome, comprising cryptic peptides with distinct bioactivities.

Drug Discov Today 2006 Apr;11(7-8):306-14

Cryptome Pharmaceuticals, PO Box 6492, St. Kilda Rd Central, Melbourne, Vic 8008, Australia.

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April 2006

Report of the working group on crystal phase identifiers.

Acta Crystallogr A 2005 Nov 22;61(Pt 6):575-80. Epub 2005 Oct 22.

Brockhouse Institute for Materials Research, McMaster University, Hamilton, Ontario L8S 4M1, Canada.

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November 2005

Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner.

Blood 2005 Oct 28;106(8):2750-6. Epub 2005 Jun 28.

Department of Biology, University of Memphis, Memphis, TN 38152, USA.

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October 2005

Role of calmodulin in platelet receptor function.

Curr Med Chem Cardiovasc Hematol Agents 2005 Oct;3(4):283-7

Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3168, Australia.

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October 2005

A critical role for 14-3-3zeta protein in regulating the VWF binding function of platelet glycoprotein Ib-IX and its therapeutic implications.

Blood 2005 Sep 7;106(6):1975-81. Epub 2005 Jun 7.

Department of Pharmacology, College of Medicine, University of Illinois at Chicago, 835 South Wolcott Ave, Chicago, IL 60612, USA.

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September 2005

Snake venom probes of platelet adhesion receptors and their ligands.

Toxicon 2005 Jun 19;45(8):1051-61. Epub 2005 Apr 19.

Department of Biochemistry and Molecular Biology, Monash University, Wellington Road, Clayton, Vic. 3168, Australia.

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June 2005

Platelet physiology and thrombosis.

Thromb Res 2004 ;114(5-6):447-53

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3168, Australia.

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April 2005

Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members.

Blood 2005 Apr 4;105(8):3169-77. Epub 2005 Jan 4.

Hanson Institute, Institute of Medical and Veterinary Science, Adelaide, SA, Australia.

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April 2005

Glycoprotein VI is associated with GPIb-IX-V on the membrane of resting and activated platelets.

Thromb Haemost 2005 Apr;93(4):716-23

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3168, Australia.

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April 2005

Primary platelet adhesion receptors.

IUBMB Life 2005 Feb;57(2):103-8

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.

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February 2005

Regulation of platelet membrane levels of glycoprotein VI by a platelet-derived metalloproteinase.

Blood 2004 Dec 12;104(12):3611-7. Epub 2004 Aug 12.

Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia, 3800.

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December 2004

The alpha1 helix-beta13 strand spanning Leu214 to Val229 of platelet glycoprotein Ibalpha facilitates the interaction with von Willebrand factor: evidence from characterization of the epitope of monoclonal antibody AP1.

Blood 2004 Dec 19;104(13):3971-8. Epub 2004 Aug 19.

Thrombosis Research Section, Baylor College of Medicine, BCM 286, N1319, 1 Baylor Plaza, Houston, TX 77030, USA.

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December 2004

Snake venom toxins affecting platelet function.

Methods Mol Biol 2004 ;273:335-48

Department of Biochemistry and Molecular Biology, Monas University, Clayton, Victoria, Australia.

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October 2004

Binding of von Willebrand factor to the small proteoglycan decorin.

FEBS Lett 2004 Sep;574(1-3):95-100

Department of Biochemistry, Center of Excellence for Applied Biology, University of Pavia, Pavia, Italy.

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September 2004

The LFA-1-associated molecule PTA-1 (CD226) on T cells forms a dynamic molecular complex with protein 4.1G and human discs large.

J Biol Chem 2004 Aug 11;279(32):33816-28. Epub 2004 May 11.

Cancer Research Unit, School of Biomedical Sciences, The University of Newcastle, University Drive, Callaghan, New South Wales 2308, Australia.

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August 2004

Identification of a novel 14-3-3zeta binding site within the cytoplasmic tail of platelet glycoprotein Ibalpha.

Blood 2004 Jul 30;104(2):420-7. Epub 2004 Mar 30.

INSERM U.311, Etablissement Français du Sang-Alsace, 10 rue Spielmann, BP 36, 67065 Strasbourg Cedex, France.

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July 2004

Serotonin blockade protects against early microvascular constriction following atherosclerotic plaque rupture.

Eur J Pharmacol 2004 Feb;486(1):85-9

Baker Heart Research Institute, Alfred Hospital, Commercial Road, Prahran, Melbourne 3181, Australia.

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February 2004

Platelet interactions in thrombosis.

IUBMB Life 2004 Jan;56(1):13-8

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3168, Australia.

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January 2004

Delineation of the region in the glycoprotein VI tail required for association with the Fc receptor gamma-chain.

J Biol Chem 2003 Sep 7;278(38):35914-22. Epub 2003 Jul 7.

Division of Medical Sciences, The Medical School Edgbaston, Birmingham B15 2TT, United Kingdom.

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September 2003

The dimeric versus monomeric status of 14-3-3zeta is controlled by phosphorylation of Ser58 at the dimer interface.

J Biol Chem 2003 Sep 15;278(38):36323-7. Epub 2003 Jul 15.

Cytokine Receptor Laboratory, Division of Human Immunology, Hanson Institute, Institute of Medical and Veterinary Science, G. P. O. Box 14 Rundle Mall, Adelaide, SA 5000, Australia.

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September 2003

Structure-activity relationships of snake toxins targeting platelet receptors, glycoprotein Ib-IX-V and glycoprotein VI.

Curr Med Chem Cardiovasc Hematol Agents 2003 Jun;1(2):143-9

Vascular Biology Laboratory, Department of Biochemistry and Molecular Biology, Monash University, Clayton 3168, Australia.

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June 2003

Interaction between von Willebrand factor and glycoprotein Ib activates Src kinase in human platelets: role of phosphoinositide 3-kinase.

Blood 2003 May 29;101(9):3469-76. Epub 2002 Aug 29.

Department of Clinical and Laboratory Medicine, Faculty of Medicine, University of Yamanashi, Tamaho, Nakakoma, Yamanashi, Japan.

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May 2003

Platelet physiology: in cold blood.

Curr Biol 2003 Apr;13(7):R282-4

Department of Biochemistry and Molecular Biology, Monash University, Clayton, 3168, Victoria, Australia.

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April 2003

Regulation of glycoprotein Ib-IX-von Willebrand factor interaction by cAMP-dependent protein kinase-mediated phosphorylation at Ser 166 of glycoprotein Ib(beta).

J Biol Chem 2002 Dec 1;277(49):47080-7. Epub 2002 Oct 1.

Department of Pharmacology, University of Illinois, College of Medicine, Chicago, Illinois 60612, USA.

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December 2002

Interaction of calmodulin with the cytoplasmic domain of platelet glycoprotein VI.

Blood 2002 Jun;99(11):4219-21

Hazel and Pip Appel Vascular Biology Laboratory, Baker Medical Research Institute, Melbourne, Australia.

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June 2002