Michael A Silverman

Michael A Silverman

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Michael A Silverman

Michael A Silverman

Publications by authors named "Michael A Silverman"

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Diet-induced microbial autofluorescence confounds flow cytometry of ex vivo isolated fecal microbes.

Eur J Immunol 2019 Aug 20. Epub 2019 Aug 20.

Division of Infectious Disease, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104.

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http://dx.doi.org/10.1002/eji.201948087DOI Listing
August 2019

A catalytic antioxidant for limiting amyloid-beta peptide aggregation and reactive oxygen species generation.

Chem Sci 2019 Feb 3;10(6):1634-1643. Epub 2018 Dec 3.

Department of Chemistry , Simon Fraser University , V5A-1S6 , Burnaby , BC , Canada . Email:

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http://dx.doi.org/10.1039/c8sc04660cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369440PMC
February 2019

In vivo induction of membrane damage by β-amyloid peptide oligomers.

Acta Neuropathol Commun 2018 11 29;6(1):131. Epub 2018 Nov 29.

Department of Integrative Physiology, University of Colorado at Boulder, Boulder, CO, USA.

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https://actaneurocomms.biomedcentral.com/articles/10.1186/s4
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http://dx.doi.org/10.1186/s40478-018-0634-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263551PMC
November 2018

Pharmacological Inhibition of O-GlcNAcase Enhances Autophagy in Brain through an mTOR-Independent Pathway.

ACS Chem Neurosci 2018 06 5;9(6):1366-1379. Epub 2018 Mar 5.

Department of Chemistry , Simon Fraser University , Burnaby , British Columbia V5A 1S6 , Canada.

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http://dx.doi.org/10.1021/acschemneuro.8b00015DOI Listing
June 2018

Valproic Acid Suppositories for Management of Seizures for Geriatric Patients.

Consult Pharm 2016;31(6):313-9

Veterans Affairs Medical Center Pharmacy (119), 7305 North Military Trail, West Palm Beach, Florida, USA.

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http://dx.doi.org/10.4140/TCP.n.2016.313DOI Listing
April 2018

Impact of Antibiotics on Necrotizing Enterocolitis and Antibiotic-Associated Diarrhea.

Gastroenterol Clin North Am 2017 03;46(1):61-76

Division of Infectious Diseases, Department of Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, 3535 Market Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.gtc.2016.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314436PMC
March 2017

Discontinuation of Statins at the End of Life #322.

J Palliat Med 2017 02 18;20(2):199-200. Epub 2016 Nov 18.

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http://dx.doi.org/10.1089/jpm.2016.0436DOI Listing
February 2017

Imaging organelle transport in primary hippocampal neurons treated with amyloid-β oligomers.

Methods Cell Biol 2016 2;131:425-51. Epub 2015 Sep 2.

Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada; Department of Biological Sciences, Simon Fraser University, Burnaby, BC, Canada; Brain Research Centre, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/bs.mcb.2015.06.012DOI Listing
October 2016

Stochastic Subcellular Organization of Dense-Core Vesicles Revealed by Point Pattern Analysis.

Biophys J 2016 Aug;111(4):852-863

Department of Physics, Lewis & Clark College, Portland, Oregon; Program in Biochemistry and Molecular Biology, Lewis & Clark College, Portland, Oregon. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2016.07.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002077PMC
August 2016

Potential Conflicting Interests for Surgeons in End-of-Life Care.

Am J Hosp Palliat Care 2015 Nov 28;32(7):763-6. Epub 2014 Jul 28.

University of Central Florida College of Medicine, Orlando, FL, USA.

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http://dx.doi.org/10.1177/1049909114543321DOI Listing
November 2015

Addressing the Shortage of Geriatricians: What Medical Educators Can Learn From the Nurse Practitioner Training Model.

Acad Med 2015 Sep;90(9):1236-40

A.G. Golden is associate professor of internal medicine, University of Central Florida College of Medicine, and associate chief of staff for geriatrics and extended care, Orlando Veterans Affairs Medical Center, Orlando, Florida. M.A. Silverman is chief of geriatrics, West Palm Beach Veterans Affairs Medical Center, West Palm Beach, Florida. S.B. Issenberg is Michael S. Gordon Professor of Medicine and Medical Education, associate dean for research in medical education, and director, Gordon Center for Research in Medical Education, Miller School of Medicine, University of Miami, Miami, Florida.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/ACM.0000000000000822DOI Listing
September 2015

Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons.

Acta Neuropathol Commun 2015 Aug 21;3:51. Epub 2015 Aug 21.

Department of Neuroscience, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan.

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http://dx.doi.org/10.1186/s40478-015-0230-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546183PMC
August 2015

Mycalolide B dissociates dynactin and abolishes retrograde axonal transport of dense-core vesicles.

Mol Biol Cell 2015 Jul 28;26(14):2664-72. Epub 2015 May 28.

Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261

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http://dx.doi.org/10.1091/mbc.E14-11-1564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501363PMC
July 2015

Modulation of insulin signaling rescues BDNF transport defects independent of tau in amyloid-β oligomer-treated hippocampal neurons.

Neurobiol Aging 2015 Mar 3;36(3):1378-82. Epub 2014 Dec 3.

Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada; Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.11.018DOI Listing
March 2015

Dendritic and axonal mechanisms of Ca2+ elevation impair BDNF transport in Aβ oligomer-treated hippocampal neurons.

Mol Biol Cell 2015 Mar 21;26(6):1058-71. Epub 2015 Jan 21.

Department of Molecular Biology and Biochemistry and Department of Biological Sciences, Simon Fraser University, Burnaby, BC V5A 1S6, Canada Brain Research Centre, University of British Columbia, Vancouver, BC V6T 2B5, Canada

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https://www.molbiolcell.org/doi/10.1091/mbc.E14-12-1612
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http://dx.doi.org/10.1091/mbc.E14-12-1612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357506PMC
March 2015

Atlas stumbled: kinesin light chain-1 variant E triggers a vicious cycle of axonal transport disruption and amyloid-β generation in Alzheimer's disease.

Bioessays 2015 Feb 13;37(2):131-41. Epub 2014 Nov 13.

Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada.

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http://dx.doi.org/10.1002/bies.201400131DOI Listing
February 2015

Electronic health records: an awkward third wheel.

South Med J 2014 Jun;107(6):380

From the University of Central Florida College of Medicine, Orlando, the West Palm Beach Veterans Affairs Medical Center, West Palm Beach, and the College of Health and Public Affairs, University of Central Florida, Orlando.

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http://dx.doi.org/10.14423/01.SMJ.0000450717.61421.54DOI Listing
June 2014

Activity-dependent secretion of progranulin from synapses.

J Cell Sci 2013 Dec 17;126(Pt 23):5412-21. Epub 2013 Sep 17.

Department of Cellular and Physiological Sciences and the Brain Research Centre, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6T-1Z3, Canada.

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http://dx.doi.org/10.1242/jcs.132076DOI Listing
December 2013

A truncating mutation of Alms1 reduces the number of hypothalamic neuronal cilia in obese mice.

Dev Neurobiol 2013 Jan 20;73(1):1-13. Epub 2012 Jul 20.

Liver Research Group, ANU Medical School at The Canberra Hospital, Canberra, ACT, Australia.

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http://dx.doi.org/10.1002/dneu.22031DOI Listing
January 2013

Providing support through life's final chapter for those who made it home.

Mil Med 2012 Dec;177(12):1498-501

Orlando VA Medical Center, 5201 Raymond Street, Orlando, FL 32803, USA.

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http://dx.doi.org/10.7205/milmed-d-12-00315DOI Listing
December 2012

Is geriatric medicine terminally ill?

Ann Intern Med 2012 May;156(9):654-6

University of Central Florida College of Medicine, Orlando, USA.

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http://dx.doi.org/10.7326/0003-4819-156-9-201205010-00009DOI Listing
May 2012

A fourth-year medical school clerkship that addressed negative attitudes toward geriatric medicine.

J Am Geriatr Soc 2010 Apr;58(4):746-50

Geriatric Research, Education, and Clinical Center and Research Service, Bruce W. Carter Veterans Affairs Medical Center, Miami, Florida 33125, USA.

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http://dx.doi.org/10.1111/j.1532-5415.2010.02774.xDOI Listing
April 2010

Home and community-based Medicaid options for dependent older Floridians.

J Am Geriatr Soc 2010 Feb 8;58(2):371-6. Epub 2010 Jan 8.

Geriatric Research, Education, and Clinical Center and Research Service, Bruce W. Carter Veterans Affairs Medical Center, Miami, Florida 33125, USA.

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http://dx.doi.org/10.1111/j.1532-5415.2009.02668.xDOI Listing
February 2010

Cooperation of adapter molecules in proximal signaling cascades during allergic inflammation.

Immunol Rev 2009 Nov;232(1):99-114

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/j.1600-065X.2009.00825.xDOI Listing
November 2009

Intraflagellar transport and the generation of dynamic, structurally and functionally diverse cilia.

Trends Cell Biol 2009 Jul 25;19(7):306-16. Epub 2009 Jun 25.

Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, V5A 1S6, Canada.

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http://dx.doi.org/10.1016/j.tcb.2009.04.002DOI Listing
July 2009

Assessing advance directives in the homebound elderly.

Am J Hosp Palliat Care 2009 Feb-Mar;26(1):13-7. Epub 2008 Oct 8.

Geriatric Research, Education, and Clinical Center, Miami VA Healthcare System, 1201 NW 16th Street, Miami, FL 33125, USA.

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http://journals.sagepub.com/doi/10.1177/1049909108324359
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http://dx.doi.org/10.1177/1049909108324359DOI Listing
May 2009

Live imaging of dense-core vesicles in primary cultured hippocampal neurons.

J Vis Exp 2009 May 29(27). Epub 2009 May 29.

Department of Biological Sciences, Simon Fraser University, Canada.

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http://dx.doi.org/10.3791/1144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762918PMC
May 2009

The beta amyloid peptide can act as a modular aggregation domain.

Neurobiol Dis 2008 Dec 22;32(3):420-5. Epub 2008 Aug 22.

Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S096999610800189
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http://dx.doi.org/10.1016/j.nbd.2008.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646107PMC
December 2008

Impaired degranulation but enhanced cytokine production after Fc epsilonRI stimulation of diacylglycerol kinase zeta-deficient mast cells.

J Exp Med 2006 Jun 22;203(6):1471-80. Epub 2006 May 22.

The Signal Transduction Program, The Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1084/jem.20052424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118304PMC
June 2006

Cutaneous malignant melanoma.

Mayo Clin Proc 2006 Apr;81(4):500-7

Department of Dermatology, The Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.4065/81.4.500DOI Listing
April 2006

Disruption of SLP-76 interaction with Gads inhibits dynamic clustering of SLP-76 and FcepsilonRI signaling in mast cells.

Mol Cell Biol 2006 Mar;26(5):1826-38

Abramson Family Cancer Research Institute, Department of Pathology and Laboratory Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1128/MCB.26.5.1826-1838.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1430252PMC
March 2006

Conversion of green fluorescent protein into a toxic, aggregation-prone protein by C-terminal addition of a short peptide.

J Biol Chem 2006 Jan 19;281(3):1808-16. Epub 2005 Oct 19.

Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309, USA.

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http://dx.doi.org/10.1074/jbc.M505581200DOI Listing
January 2006

SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond.

Nat Rev Immunol 2006 Jan;6(1):67-78

Department of Pathology and Laboratory Medicine, Abramson Family Cancer Research Institute, University of Pennsylvania, 415 BRBII/III, 421 Curie Boulevard, Philadelphia, Pennsylvania 19104, USA.

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http://www.nature.com/articles/nri1750
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http://dx.doi.org/10.1038/nri1750DOI Listing
January 2006

A cytoplasmic motif targets neuroligin-1 exclusively to dendrites of cultured hippocampal neurons.

Eur J Neurosci 2005 Nov;22(9):2381-6

Department of Biological Sciences, California State University Polytechnic, Pomona, CA, USA.

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http://dx.doi.org/10.1111/j.1460-9568.2005.04400.xDOI Listing
November 2005

Membrane cholesterol content accounts for developmental differences in surface B cell receptor compartmentalization and signaling.

J Biol Chem 2005 Jul 5;280(27):25621-8. Epub 2005 May 5.

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6160, USA.

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http://dx.doi.org/10.1074/jbc.M503162200DOI Listing
July 2005

Differential requirement for adapter proteins Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and adhesion- and degranulation-promoting adapter protein in FcepsilonRI signaling and mast cell function.

J Immunol 2004 Jun;172(11):6768-74

Abramson Family Cancer Research Institute and Department of Laboratory Medicine and Pathology, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.4049/jimmunol.172.11.6768DOI Listing
June 2004

University of Miami Division of Clinical Pharmacology Therapeutic Rounds: medications used to treat anorexia in the frail elderly.

Am J Ther 2003 Jul-Aug;10(4):292-8

Department of Internal Medicine, Orlando Regional Healthcare, Orlando, Florida 32806, USA.

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November 2003

SLP-76 regulates Fcgamma receptor and integrin signaling in neutrophils.

Immunity 2003 Nov;19(5):761-9

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/s1074-7613(03)00305-4DOI Listing
November 2003