Michael A Pulsipher

Michael A Pulsipher

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Michael A Pulsipher

Michael A Pulsipher

Publications by authors named "Michael A Pulsipher"

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Methods and role of minimal residual disease after stem cell transplantation.

Bone Marrow Transplant 2019 May 16;54(5):681-690. Epub 2018 Aug 16.

Medical Center of the Johann-Wolfgang Goethe University, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1038/s41409-018-0307-1DOI Listing
May 2019

Tisagenlecleucel Model-Based Cellular Kinetic Analysis of Chimeric Antigen Receptor-T Cells.

CPT Pharmacometrics Syst Pharmacol 2019 May 7;8(5):285-295. Epub 2019 Mar 7.

Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1002/psp4.12388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539725PMC
May 2019

Related peripheral blood stem cell donors experience more severe symptoms and less complete recovery at one year compared to unrelated donors.

Haematologica 2019 Apr 31;104(4):844-854. Epub 2018 Oct 31.

Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, WI.

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http://www.haematologica.org/lookup/doi/10.3324/haematol.201
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http://dx.doi.org/10.3324/haematol.2018.200121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442962PMC
April 2019

Effect of Aging and Predonation Comorbidities on the Related Peripheral Blood Stem Cell Donor Experience: Report from the Related Donor Safety Study.

Biol Blood Marrow Transplant 2019 04 10;25(4):699-711. Epub 2018 Nov 10.

Center for International Blood and Marrow Transplant Research, Minneapolis, Minnesota; National Marrow Donor Program/Be the Match, Minneapolis, Minnesota.

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http://dx.doi.org/10.1016/j.bbmt.2018.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453753PMC
April 2019

Advances in hematopoietic cell transplant for the treatment of hematologic malignancies.

Curr Opin Pediatr 2019 02;31(1):3-13

Division of Pediatric Hematology, Oncology and Blood and Marrow Transplantation, Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, California, USA.

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http://dx.doi.org/10.1097/MOP.0000000000000729DOI Listing
February 2019

Are CAR T cells better than antibody or HCT therapy in B-ALL?

Hematology Am Soc Hematol Educ Program 2018 11;2018(1):16-24

University of Southern California Keck School of Medicine, Children's Hospital Los Angeles, Los Angeles CA.

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http://dx.doi.org/10.1182/asheducation-2018.1.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246000PMC
November 2018

SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery.

Blood 2018 10 28;132(17):1737-1749. Epub 2018 Aug 28.

Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1182/blood-2018-03-840702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202916PMC
October 2018

Myeloid lineage switch following chimeric antigen receptor T-cell therapy in a patient with TCF3-ZNF384 fusion-positive B-lymphoblastic leukemia.

Pediatr Blood Cancer 2018 09 24;65(9):e27265. Epub 2018 May 24.

Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California.

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http://doi.wiley.com/10.1002/pbc.27265
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http://dx.doi.org/10.1002/pbc.27265DOI Listing
September 2018

Selected biological issues affecting relapse after stem cell transplantation: role of T-cell impairment, NK cells and intrinsic tumor resistance.

Bone Marrow Transplant 2018 08 24;53(8):949-959. Epub 2018 Jan 24.

Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1038/s41409-017-0078-0DOI Listing
August 2018

Dasatinib Plus Intensive Chemotherapy in Children, Adolescents, and Young Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Results of Children's Oncology Group Trial AALL0622.

J Clin Oncol 2018 08 29;36(22):2306-2314. Epub 2018 May 29.

William B. Slayton, John A. Kairalla, Meenakshi Devidas, Xinlei Mi, and Sherri L. Mizrahy, University of Florida, Gainesville, FL; Kirk R. Schultz, BC Children's Research Institute, University of British Columbia, Vancouver, British Columbia, Canada; Michael A. Pulsipher, Children's Hospital of Los Angeles, Los Angeles; Lance Sieger, University of California Los Angles-Harbor, Torrance; Mignon L. Loh, University of California San Francisco, San Francisco, CA; Bill H. Chang, Oregon Health and Science University, Portland, OR; Charles Mullighan, Ilaria Iacobucci, and Thomas Merchant, St Jude's Research Hospital, Memphis, TN; Lewis B. Silverman, Dana-Farber Cancer Institute, Boston, MA; Michael J. Borowitz, Johns Hopkins University, Baltimore, MD; Andrew J. Carroll, University of Alabama at Birmingham, Birmingham, AL; Nyla A. Heerema, Ohio State University; Julie M. Gastier-Foster, Nationwide Children's Hospital, Columbus, OH; Brent L. Wood, University of Washington Seattle, Seattle, WA; Valerie I. Brown, Penn State Health Children's Hospital, Hershey; Stephen P. Hunger, Children's Hospital of Philadelphia, Philadelphia, PA; Marilyn J. Siegel, Washington University School of Medicine, St Louis, MO; Elizabeth A. Raetz, University of Utah, Salt Lake City, UT; Naomi J. Winick, University of Texas Southwestern Medical Center, Dallas, TX; and William L. Carroll, New York University Langone Health Center, New York, NY.

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http://dx.doi.org/10.1200/JCO.2017.76.7228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067800PMC
August 2018

Hypogammaglobulinemia due to CAR T-cell therapy.

Pediatr Blood Cancer 2018 04 12;65(4). Epub 2017 Dec 12.

Division of Hematology, Oncology, and Blood and Marrow Transplantation, Children's Hospital Los Angeles, Keck School of Medicine of USC, Los Angeles, California.

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http://doi.wiley.com/10.1002/pbc.26914
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http://dx.doi.org/10.1002/pbc.26914DOI Listing
April 2018

Reversal of Low Donor Chimerism after Hematopoietic Cell Transplantation Using Pentostatin and Donor Lymphocyte Infusion: A Prospective Phase II Multicenter Trial.

Biol Blood Marrow Transplant 2018 02 12;24(2):308-313. Epub 2017 Oct 12.

Clinical Research Division, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2017.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767527PMC
February 2018

Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia.

N Engl J Med 2018 02;378(5):439-448

From the Departments of Pediatrics (S.L.M., S.A.G.) and Pathology and Laboratory Medicine (C.H.J., B.L.L.), Perelman School of Medicine, and Abramson Cancer Center (C.H.J., B.L.L.), University of Pennsylvania, and the Division of Oncology, Center for Childhood Cancer Research and Cancer Immunotherapy Program, Children's Hospital of Philadelphia (S.L.M., S.A.G.) - all in Philadelphia; the Department of Pediatrics and Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, and the Pauline Allen Gill Center for Cancer and Blood Disorders, Children's Health, Dallas (T.W.L.); the Department of Pediatric Hematology and Oncology, Oslo University Hospital, Oslo (J.B.); the Department of Pediatric Hematology and Oncology, Hospital Sant Joan de Deu Barcelona, Barcelona (S.R.); the Department of Pediatrics and Internal Medicine, University of Utah, Salt Lake City (M.B.); the Department of Pediatrics, Faculty of Medicine, University of Montreal, and the Hematology Oncology Division and Charles-Bruneau Cancer Center, Centre Hospitalier Universitaire Sainte-Justine Research Center, Montreal (H.B.), and the Division of Haematology/Oncology/Bone Marrow Transplantation, Hospital for Sick Children, Toronto (J.K.) - all in Canada; the Division of Stem Cell Transplantation and Immunology, Hospital for Children and Adolescents, University Hospital Frankfurt, Frankfurt, Germany (P.B.); the Division of Pediatric Blood and Marrow Transplant, University of Minnesota, Minneapolis (M.R.V., H.E.S.); Children's Mercy Hospital and Clinics, Kansas City, MO (G.D.M.); Aflac Cancer and Blood Disorders Center, Emory University, Atlanta (M.Q.); the Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, and the Cancer Research Institute Ghent (CRIG), Ghent, Belgium (B.D.M.); the Department of Pediatrics, Graduate School of Medicine Kyoto University, Kyoto, Japan (H.H.); the Department of Pediatrics, Stanford University School of Medicine, Stanford (K. Schlis, K.L.D.), and the Division of Hematology, Oncology, Blood and Marrow Transplant, Children's Hospital Los Angeles, USC Keck School of Medicine, Los Angeles (M.A.P.) - all in California; the Division of Pediatric Blood and Marrow Transplant, Duke University Medical Center, Durham, NC (P.L.M.); Oregon Health and Science University, Portland (E.R.N.); C.S. Mott Children's Hospital, Ann Arbor, MI (G.A.Y.); the Stem Cell Transplantation Unit, St. Anna Children's Hospital, Vienna (C.P.); University Hospital Robert Debré and University Paris Diderot (A. Baruchel), and Saint-Louis Hospital and University Paris Diderot (N.B.), Paris; the Royal Children's Hospital, Melbourne, VIC, Australia (F.M.); Clinica Pediatrica Universita degli Studi di Milano Bicocca, Monza, Italy (A. Balduzzi); and Novartis Pharmaceuticals (P.W., T.T., M.L., Y.Z., K. Sen, D.L.) and Novartis Institutes for Biomedical Research (K.T.M.) - both in East Hanover, NJ.

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http://dx.doi.org/10.1056/NEJMoa1709866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996391PMC
February 2018

Reduced Intensity for Myelodysplastic Syndrome: Worth the Gamble?

J Clin Oncol 2017 07 2;35(19):2106-2108. Epub 2017 May 2.

Michael A. Pulsipher, Children's Hospital Los Angeles, Los Angeles, CA.

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http://dx.doi.org/10.1200/JCO.2017.72.8048DOI Listing
July 2017

Long-Term Follow-Up after Reduced-Intensity Conditioning and Stem Cell Transplantation for Childhood Nonmalignant Disorders.

Biol Blood Marrow Transplant 2016 08 6;22(8):1467-1472. Epub 2016 May 6.

Division of Pediatric Hematology Oncology, Washington University School of Medicine, St. Louis, Missouri. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2016.04.025DOI Listing
August 2016

Deficient Neutrophil Extracellular Trap Formation in Patients Undergoing Bone Marrow Transplantation.

Front Immunol 2016 27;7:250. Epub 2016 Jun 27.

Division of Neonatology, Department of Pediatrics, University of Utah School of Medicine , Salt Lake City, UT , USA.

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http://dx.doi.org/10.3389/fimmu.2016.00250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921458PMC
July 2016

Research involving pediatric stem cell donors: A way forward.

Clin Trials 2016 06 17;13(3):304-10. Epub 2016 Feb 17.

Department of Bioethics, NIH Clinical Center, Bethesda, MD, USA.

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http://dx.doi.org/10.1177/1740774515627156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965294PMC
June 2016

Accuracy of Adverse Event Ascertainment in Clinical Trials for Pediatric Acute Myeloid Leukemia.

J Clin Oncol 2016 05 16;34(13):1537-43. Epub 2016 Feb 16.

Tamara P. Miller, Yimei Li, Marko Kavcic, Yuan-Shun V. Huang, Rochelle Bagatell, Alix E. Seif, Brian T. Fisher, Peter C. Adamson, and Richard Aplenc, The Children's Hospital of Philadelphia; Yimei Li, Andrea B. Troxel, Rochelle Bagatell, Alix E. Seif, Brian T. Fisher, Selina Luger, Peter C. Adamson, and Richard Aplenc, University of Pennsylvania School of Medicine, Philadelphia, PA; Lillian Sung, The Hospital for Sick Children, Toronto, Ontario, Canada; Todd A. Alonzo and Michael A. Pulsipher, University of Southern California; Michael A. Pulsipher, Children's Hospital of Los Angeles, Los Angeles; Todd A. Alonzo and Robert Gerbing, Children's Oncology Group, Monrovia, CA; Matt Hall, Children's Hospital Association, Overland Park, Kansas; Marla H. Daves, Children's Healthcare of Atlanta, Atlanta, GA; Terzah M. Horton, Texas Children's Hospital, Houston, TX; Jessica A. Pollard, Seattle Children's Hospital, Seattle, WA; and Alan S. Gamis, Children's Mercy Hospital, Kansas City, MO.

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http://dx.doi.org/10.1200/JCO.2015.65.5860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872308PMC
May 2016

Evolving hematopoietic stem cell transplantation strategies in severe aplastic anemia.

Curr Opin Pediatr 2016 Feb;28(1):3-11

aChildren's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, California, USA bDepartment of Paediatric Bone Marrow Transplant cDepartment of Paediatric Haematology, Great Ormond Street Hospital, London, UK *Andrew C. Dietz and Giovanna Lucchini contributed equally to the writing of this article.

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http://dx.doi.org/10.1097/MOP.0000000000000299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725196PMC
February 2016

Fishing for complements.

Blood 2016 Feb;127(8):957-8

UNIVERSITY OF SOUTHERN CALIFORNIA KECK SCHOOL OF MEDICINE.

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http://dx.doi.org/10.1182/blood-2015-12-685131DOI Listing
February 2016

Challenges in the harmonization of immune monitoring studies and trial design for cell-based therapies in the context of hematopoietic cell transplantation for pediatric cancer patients.

Cytotherapy 2015 Dec;17(12):1667-74

Blood and Marrow Transplantation Program, Department of Pediatrics, UMC Utrecht, Utrecht, Netherlands; Laboratory of Translational Immunology, UMC Utrecht, Utrecht, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2015.09.008DOI Listing
December 2015

IgH-V(D)J NGS-MRD measurement pre- and early post-allotransplant defines very low- and very high-risk ALL patients.

Blood 2015 May 10;125(22):3501-8. Epub 2015 Apr 10.

Division of Oncology, Children's Hospital of Philadelphia, and Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; Department of Pathology, Children's Hospital of Philadelphia, and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-12-61
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http://dx.doi.org/10.1182/blood-2014-12-615757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447864PMC
May 2015

Will post-transplantation cell therapies for pediatric patients become standard of care?

Biol Blood Marrow Transplant 2015 Mar 23;21(3):402-11. Epub 2014 Jul 23.

Departments of Pediatrics and Microbiology, Immunology and Tropical Medicine, Children's National Health System and George Washington University, Division of Pediatric Hematology-Oncology, Washington, DC.

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https://linkinghub.elsevier.com/retrieve/pii/S10838791140044
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http://dx.doi.org/10.1016/j.bbmt.2014.07.018DOI Listing
March 2015

Long-term outcomes in MPS-IH: throwing stars.

Blood 2015 Mar;125(13):2016-7

HUNTSMAN CANCER INSTITUTE; UNIVERSITY OF UTAH SCHOOL OF MEDICINE; PRIMARY CHILDREN'S HOSPITAL.

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http://dx.doi.org/10.1182/blood-2015-02-626507DOI Listing
March 2015

Chimerism versus minimal residual disease monitoring after allogeneic transplantation--when do we act and will intervention improve outcomes?

Biol Blood Marrow Transplant 2014 Oct 29;20(10):1461-2. Epub 2014 Jul 29.

Division of Hematology and Hematological Malignancies, Huntsman Cancer Institute/University of Utah School of Medicine, Primary Children's Hospital, Salt Lake City, Utah. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2014.07.026DOI Listing
October 2014

Comorbidity-age index: a clinical measure of biologic age before allogeneic hematopoietic cell transplantation.

J Clin Oncol 2014 Oct 25;32(29):3249-56. Epub 2014 Aug 25.

Mohamed L. Sorror, Rainer F. Storb, Brenda M. Sandmaier, Fabiana Ostronoff, H. Joachim Deeg, Karen L. Syrjala, Elihu Estey, David G. Maloney, Frederick R. Appelbaum, Paul J. Martin, and Barry E. Storer, Fred Hutchinson Cancer Research Center; Mohamed L. Sorror, Rainer F. Storb, Brenda M. Sandmaier, Fabiana Ostronoff, H. Joachim Deeg, Karen L. Syrjala, Elihu Estey, David G. Maloney, Frederick R. Appelbaum, and Paul J. Martin, University of Washington School of Medicine; Barry E. Storer, University of Washington School of Public Health, Seattle, WA; Smita Bhatia, City of Hope School of Medicine, Duarte, CA; Richard T. Maziarz, Center for Hematologic Malignancies, Oregon Health & Science University Knight Cancer Institute and School of Medicine, Portland, OR; Michael A. Pulsipher, University of Utah School of Medicine and Primary Children's Medical Center, Huntsman Cancer Institute, Salt Lake City, UT; and Michael B. Maris, Colorado Blood Cancer Institute School of Medicine, Denver, CO.

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http://dx.doi.org/10.1200/JCO.2013.53.8157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178523PMC
October 2014

Pretransplant comorbidities predict severity of acute graft-versus-host disease and subsequent mortality.

Blood 2014 Jul 5;124(2):287-95. Epub 2014 May 5.

Clinical Statistics Program, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA; and Department of Biostatistics, University of Washington School of Public Health, Seattle, WA.

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http://dx.doi.org/10.1182/blood-2014-01-550566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093684PMC
July 2014

Lower risk for serious adverse events and no increased risk for cancer after PBSC vs BM donation.

Blood 2014 Jun 15;123(23):3655-63. Epub 2014 Apr 15.

Center for International Blood and Marrow Transplant Research, Minneapolis, MN; National Marrow Donor Program, Minneapolis, MN;

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http://dx.doi.org/10.1182/blood-2013-12-542464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047500PMC
June 2014

Preventable Infections in Children with Leukodystrophy.

Ann Clin Transl Neurol 2014 May;1(5):370-374

Division of Pediatric Neurology (J.L.B.), Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah ; Department of Neurology (J.L.B.), Salt Lake City, Utah.

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http://doi.wiley.com/10.1002/acn3.61
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http://dx.doi.org/10.1002/acn3.61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063358PMC
May 2014

Autoimmunity due to RAG deficiency and estimated disease incidence in RAG1/2 mutations.

J Allergy Clin Immunol 2014 Mar 25;133(3):880-2.e10. Epub 2014 Jan 25.

Division of Immunology and the Manton Center for Orphan Disease Research, Boston Children's Hospital, Harvard Medical School, Boston, Mass; Pediatric Immunodeficiency Program, Division of Allergy, Massachusetts General Hospital for Children, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2013.11.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107635PMC
March 2014

Aplastic Anemia & MDS International Foundation (AA&MDSIF): bone marrow failure disease scientific symposium 2012.

Leuk Res 2013 Jul 1;37(7):848-51. Epub 2013 May 1.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, United States.

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http://dx.doi.org/10.1016/j.leukres.2013.04.013DOI Listing
July 2013

Better BMT for Hurler syndrome--on the level?

Blood 2013 May;121(19):3785-7

University of Utah School of Medicine, USA.

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http://dx.doi.org/10.1182/blood-2013-04-491779DOI Listing
May 2013