Michael A Moskowitz

Michael A Moskowitz

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Michael A Moskowitz

Publications by authors named "Michael A Moskowitz"

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Reducing myeloperoxidase activity decreases inflammation and increases cellular protection in ischemic stroke.

J Cereb Blood Flow Metab 2019 Sep 20;39(9):1864-1877. Epub 2018 Apr 20.

1 Center for System Biology and Institute for Innovation in Imaging, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1177/0271678X18771978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727136PMC
September 2019

Migraine and the trigeminovascular system-40 years and counting.

Lancet Neurol 2019 Aug 31;18(8):795-804. Epub 2019 May 31.

Department of Neurology and Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1016/S1474-4422(19)30185-1DOI Listing
August 2019

Caffeine does not affect susceptibility to cortical spreading depolarization in mice.

J Cereb Blood Flow Metab 2019 Apr 13;39(4):740-750. Epub 2018 Apr 13.

1 Neurovascular Research Laboratory, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA.

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http://dx.doi.org/10.1177/0271678X18768955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446422PMC
April 2019

Vascular dysfunction-The disregarded partner of Alzheimer's disease.

Alzheimers Dement 2019 01;15(1):158-167

Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Alzheimer's Disease Research Center, Keck School of Medicine at the University of Southern California, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.07.222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338083PMC
January 2019

Introduction to the special issue honoring Richard Traystman.

J Cereb Blood Flow Metab 2018 12;38(12):2055-2056

Departments of Radiology and Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.

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http://dx.doi.org/10.1177/0271678X18803702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282219PMC
December 2018

Richard Joel Traystman, PhD.

Stroke 2018 02 28;49(2):271-272. Epub 2017 Dec 28.

From the Harvard Medical School, Massachusetts General Hospital, Boston (M.A.M.); University of Michigan School of Nursing, Ann Arbor (P.D.H.); and Weill Cornell Medicine, New York, NY (C.I.).

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http://dx.doi.org/10.1161/STROKEAHA.117.019918DOI Listing
February 2018

Inhibition of the P2X7-PANX1 complex suppresses spreading depolarization and neuroinflammation.

Brain 2017 Jun;140(6):1643-1656

Neurovascular Research Lab, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.

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https://academic.oup.com/brain/article/140/6/1643/3744970
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http://dx.doi.org/10.1093/brain/awx085DOI Listing
June 2017

Holes in the leaky migraine blood-brain barrier hypothesis?

Brain 2017 06;140(6):1537-1539

Harvard Medical School, Massachusetts General Hospital, Boston MA 02114, USA.

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http://dx.doi.org/10.1093/brain/awx099DOI Listing
June 2017

Myeloperoxidase Inhibition Increases Neurogenesis after Ischemic Stroke.

J Pharmacol Exp Ther 2016 Nov 22;359(2):262-272. Epub 2016 Aug 22.

Center for Systems Biology and Institute for Innovation in Imaging (H.K., J.Y.L., J.W.C), and Neuroscience Center (Y. Wei, Y. Wu, Y.Z., M.A.M.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts

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http://dx.doi.org/10.1124/jpet.116.235127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074486PMC
November 2016

Headache. Preface.

Handb Clin Neurol 2010 ;97:ix-x

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http://dx.doi.org/10.1016/S0072-9752(10)97070-XDOI Listing
April 2016

Migraine general aspects.

Handb Clin Neurol 2010 ;97:253-66

Stroke and Neurovascular Regulation Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/S0072-9752(10)97021-8DOI Listing
April 2016

Cluster headache and trigeminal autonomic cephalalgias general aspects.

Handb Clin Neurol 2010 ;97:387-8

Chair of Neurology, "Sapienza" University of Rome and IRCSS "C. Mondino Institute of Neurology" Foundation, Pavia, Italy.

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http://dx.doi.org/10.1016/S0072-9752(10)97032-2DOI Listing
April 2016

Secondary headaches introduction.

Handb Clin Neurol 2010 ;97:497-500

Chair of Neurology, "Sapienza" University of Rome and IRCSS "C. Mondino Institute of Neurology" Foundation, Pavia, Italy.

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http://dx.doi.org/10.1016/S0072-9752(10)97045-0DOI Listing
April 2016

Myeloperoxidase propagates damage and is a potential therapeutic target for subacute stroke.

J Cereb Blood Flow Metab 2015 Mar 17;35(3):485-93. Epub 2014 Dec 17.

1] Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA [2] Division of Neuroradiology, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/jcbfm.2014.222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348390PMC
March 2015

Supply-demand mismatch transients in susceptible peri-infarct hot zones explain the origins of spreading injury depolarizations.

Neuron 2015 Mar;85(5):1117-31

Neurovascular Research Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 149 13(th) Street, 6408, Charlestown, MA 02129, USA; Stroke Service and Neuroscience Intensive Care Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2015.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351476PMC
March 2015

Ischemic stroke activates hematopoietic bone marrow stem cells.

Circ Res 2015 Jan 31;116(3):407-17. Epub 2014 Oct 31.

From the Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston (G.C., H.B.S., T.H., Y.Y., Y.S., P.D., J.S., R.W., F.K.S., M.N.); Stroke and Neurovascular Regulation Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital/Harvard Medical School, Charlestown (F.H., Y.W., M.A.M.); Center for Regenerative Medicine, Massachusetts General Hospital, Boston (N.S., D.T.S.); and Department of Systems Biology, Harvard Medical School, Boston, MA (R.W.).

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http://circres.ahajournals.org/content/early/2014/10/31/CIRC
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http://circres.ahajournals.org/cgi/doi/10.1161/CIRCRESAHA.11
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http://dx.doi.org/10.1161/CIRCRESAHA.116.305207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312511PMC
January 2015

Chaos and commotion in the wake of cortical spreading depression and spreading depolarizations.

Nat Rev Neurosci 2014 Jun;15(6):379-93

1] Stroke and Neurovascular Regulation Laboratory, Departments of Radiology and Neurology, 149 13th Street, Room 6403, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA. [2] Department of Neurology, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nrn3770DOI Listing
June 2014

Recognition memory impairments after subcortical white matter stroke in mice.

Stroke 2014 May 10;45(5):1468-73. Epub 2014 Apr 10.

From the Stroke and Neurovascular Research Laboratory, Department of Radiology (F.B., Y.W., M.B., C.A., M.A.M.), Stroke Service and Neuroscience Intensive Care Unit, Department of Neurology (C.A.), Department of Cell Biology (S.T.), and Department of Radiology, Martinos Center for Biomedical Imaging (J.B.M.), Massachusetts General Hospital, Harvard Medical School, Boston; and Department of Pharmacology, School of Pharmacy, University College Cork, Cork, Ireland (C.W.).

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http://stroke.ahajournals.org/content/45/5/1468.full.pdf
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http://stroke.ahajournals.org/cgi/doi/10.1161/STROKEAHA.114.
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http://dx.doi.org/10.1161/STROKEAHA.114.005324DOI Listing
May 2014

The innate immune system after ischemic injury: lessons to be learned from the heart and brain.

JAMA Neurol 2014 Feb;71(2):233-6

Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston.

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http://dx.doi.org/10.1001/jamaneurol.2013.5026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946050PMC
February 2014

Diffusion tensor and volumetric magnetic resonance imaging using an MR-compatible hand-induced robotic device suggests training-induced neuroplasticity in patients with chronic stroke.

Int J Mol Med 2013 Nov 27;32(5):995-1000. Epub 2013 Aug 27.

NMR Surgical Laboratory, Department of Surgery, Massachusetts General Hospital and Shriners Burn Institute, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.3892/ijmm.2013.1476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820572PMC
November 2013

Pathophysiology of migraine.

Annu Rev Physiol 2013 26;75:365-91. Epub 2012 Nov 26.

Department of Biomedical Sciences, University of Padova, Padova, Italy.

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http://www.annualreviews.org/doi/10.1146/annurev-physiol-030
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http://dx.doi.org/10.1146/annurev-physiol-030212-183717DOI Listing
August 2013

The NINDS Stroke Progress Review Group final analysis and recommendations.

Stroke 2013 Aug 2;44(8):2343-50. Epub 2013 Jul 2.

Neuroscience Center at Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1161/STROKEAHA.113.001192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863937PMC
August 2013

Nitric oxide: considerations for the treatment of ischemic stroke.

J Cereb Blood Flow Metab 2012 Jul 15;32(7):1332-46. Epub 2012 Feb 15.

Department of Neurosurgery, University of Munich Medical School, Munich, Germany.

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http://dx.doi.org/10.1038/jcbfm.2012.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390820PMC
July 2012

Migraine mutations increase stroke vulnerability by facilitating ischemic depolarizations.

Circulation 2012 Jan 5;125(2):335-45. Epub 2011 Dec 5.

Stroke and Neurovascular Regulation Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.111.045096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276214PMC
January 2012

Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis.

Hum Mol Genet 2011 Jun 29;20(12):2344-55. Epub 2011 Mar 29.

Molecular Neurogenetics Unit, Center for Human Genetic Research, Center for Human Genetic Research, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1093/hmg/ddr127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098733PMC
June 2011

Enhanced subcortical spreading depression in familial hemiplegic migraine type 1 mutant mice.

J Neurosci 2011 Apr;31(15):5755-63

Stroke and Neurovascular Regulation Laboratory, Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.5346-10.2
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http://dx.doi.org/10.1523/JNEUROSCI.5346-10.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135337PMC
April 2011

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy syndrome mutations increase susceptibility to spreading depression.

Ann Neurol 2011 Feb;69(2):413-8

Stroke and Neurovascular Regulation Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, USA.

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http://doi.wiley.com/10.1002/ana.22281
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http://dx.doi.org/10.1002/ana.22281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058390PMC
February 2011

The ischemic cascade and mediators of ischemic injury.

Handb Clin Neurol 2009 ;92:31-41

Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1016/S0072-9752(08)01902-7DOI Listing
December 2010

Brain protection: maybe yes, maybe no.

Stroke 2010 Oct;41(10 Suppl):S85-6

Neuroscience Center, Radiology and Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass 02129, USA.

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http://dx.doi.org/10.1161/STROKEAHA.110.598458DOI Listing
October 2010

High-mobility group box 1 promotes metalloproteinase-9 upregulation through Toll-like receptor 4 after cerebral ischemia.

Stroke 2010 Sep 29;41(9):2077-82. Epub 2010 Jul 29.

Department of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass 02129, USA.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.110.590463
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http://dx.doi.org/10.1161/STROKEAHA.110.590463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066477PMC
September 2010

The science of stroke: mechanisms in search of treatments.

Neuron 2010 Jul;67(2):181-98

Departments of Radiology and Neurology, Massachusetts General Hospital, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/j.neuron.2010.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957363PMC
July 2010

Context dependent neuroprotective properties of prion protein (PrP).

Prion 2009 Oct-Dec;3(4):240-9. Epub 2009 Oct 16.

Whitehead Institute for Biomedical Research, Howard Hughes Medical Institute, MIT, Cambridge, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807698PMC
http://dx.doi.org/10.4161/pri.3.4.10135DOI Listing
March 2010

Migraine aura pathophysiology: the role of blood vessels and microembolisation.

Lancet Neurol 2010 Mar;9(3):309-17

Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, 02129, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921876PMC
http://dx.doi.org/10.1016/S1474-4422(09)70358-8DOI Listing
March 2010

Microemboli may link spreading depression, migraine aura, and patent foramen ovale.

Ann Neurol 2010 Feb;67(2):221-9

Stroke and Neurovascular Regulation Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://doi.wiley.com/10.1002/ana.21871
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http://dx.doi.org/10.1002/ana.21871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921919PMC
February 2010

Sonic hedgehog regulates ischemia/hypoxia-induced neural progenitor proliferation.

Stroke 2009 Nov 17;40(11):3618-26. Epub 2009 Sep 17.

Department of Radiology and Neuroscience Center, Harvard Medical School, Massachusetts General Hospital, Stroke and Neurovascular Regulation Laboratory, Charlestown, Mass 02129, USA.

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http://dx.doi.org/10.1161/STROKEAHA.109.561951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869495PMC
November 2009

Connectivity alterations assessed by combining fMRI and MR-compatible hand robots in chronic stroke.

Neuroimage 2009 Aug 12;47 Suppl 2:T90-7. Epub 2009 Mar 12.

NMR Surgical Laboratory, Department of Surgery, Massachusetts General Hospital and Shriner's Burn Institute, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2009.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720432PMC
August 2009

p27Kip1 constrains proliferation of neural progenitor cells in adult brain under homeostatic and ischemic conditions.

Stem Cells 2009 Apr;27(4):920-7

Department of Radiology and Neurology, Stroke and Neurovascular Regulation Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02129, USA.

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http://doi.wiley.com/10.1002/stem.1
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http://dx.doi.org/10.1002/stem.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680235PMC
April 2009

Inhibition of cerebral vasoconstriction by dantrolene and nimodipine.

Neurocrit Care 2009 16;10(1):93-102. Epub 2008 Oct 16.

Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1007/s12028-008-9153-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744156PMC
March 2009

Rac1 is a critical mediator of endothelium-derived neurotrophic activity.

Sci Signal 2009 Mar 10;2(61):ra10. Epub 2009 Mar 10.

Vascular Medicine Research, Brigham and Women's Hospital, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1126/scisignal.2000162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668716PMC
March 2009

Tracking the inflammatory response in stroke in vivo by sensing the enzyme myeloperoxidase.

Proc Natl Acad Sci U S A 2008 Nov 14;105(47):18584-9. Epub 2008 Nov 14.

Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, CNY-149, 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1073/pnas.0803945105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587593PMC
November 2008

[Molecular mechanism of migraine].

Rinsho Shinkeigaku 2008 Nov;48(11):798

Neuroscience Center, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Room 6403, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.5692/clinicalneurol.48.798DOI Listing
November 2008

Statin potentiates human platelet eNOS activity without enhancing eNOS mRNA and protein levels.

Cerebrovasc Dis 2008 15;26(2):190-8. Epub 2008 Jul 15.

Department of Neurology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

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http://dx.doi.org/10.1159/000145327DOI Listing
October 2008

Functional MRI of Rehabilitation in Chronic Stroke Patients Using Novel MR-Compatible Hand Robots.

Open Neuroimag J 2008 Sep 27;2:94-101. Epub 2008 Sep 27.

NMR Surgical Laboratory, Department of Surgery, Massachusetts General Hospital and Shriner's Burn Institute, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.2174/1874440000802010094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695624PMC
September 2008

Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice.

J Cereb Blood Flow Metab 2008 Sep 21;28(9):1564-73. Epub 2008 May 21.

Neuroscience Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1038/jcbfm.2008.44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831087PMC
September 2008

Additive effects of statin and dipyridamole on cerebral blood flow and stroke protection.

J Cereb Blood Flow Metab 2008 Jul 2;28(7):1285-93. Epub 2008 Apr 2.

Vascular Medicine Research Unit, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/jcbfm.2008.24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662038PMC
July 2008

Hypoxia and hypotension transform the blood flow response to cortical spreading depression from hyperemia into hypoperfusion in the rat.

J Cereb Blood Flow Metab 2008 Jul 30;28(7):1369-76. Epub 2008 Apr 30.

Stroke and Neurovascular Regulation Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.

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http://journals.sagepub.com/doi/10.1038/jcbfm.2008.35
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http://dx.doi.org/10.1038/jcbfm.2008.35DOI Listing
July 2008

The impact of anesthetics and hyperoxia on cortical spreading depression.

Exp Neurol 2008 Jul 11;212(1):201-6. Epub 2008 Apr 11.

Department of Radiology, Stroke and Neurovascular Regulation Laboratory, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/j.expneurol.2008.03.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2459317PMC
July 2008

Animal models of migraine headache and aura.

Curr Opin Neurol 2008 Jun;21(3):294-300

Stroke and Neurovascular Regulation Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1097/WCO.0b013e3282fc25deDOI Listing
June 2008

Early release of HMGB-1 from neurons after the onset of brain ischemia.

J Cereb Blood Flow Metab 2008 May 14;28(5):927-38. Epub 2007 Nov 14.

Stroke and Neurovascular Regulation Laboratory, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA.

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http://journals.sagepub.com/doi/10.1038/sj.jcbfm.9600582
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http://dx.doi.org/10.1038/sj.jcbfm.9600582DOI Listing
May 2008

Mild induced hypertension improves blood flow and oxygen metabolism in transient focal cerebral ischemia.

Stroke 2008 May 13;39(5):1548-55. Epub 2008 Mar 13.

Stroke and Neurovascular Regulation Laboratory, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.107.499483
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http://dx.doi.org/10.1161/STROKEAHA.107.499483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023416PMC
May 2008

Defining a pathway to discovery from bench to bedside: the trigeminovascular system and sensitization.

Headache 2008 May;48(5):688-90

Neuroscience Center and the Stroke and Neurovascular Regulation Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/j.1526-4610.2008.01110.xDOI Listing
May 2008

Stroke program review group: an interim report.

Stroke 2008 Apr 28;39(4):1364-70. Epub 2008 Feb 28.

Department of Neurology, University of Texas-Houston Medical School, 6431 Fannin St, Houston TX 77080, USA.

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http://dx.doi.org/10.1161/STROKEAHA.107.510776DOI Listing
April 2008

Linking Notch signaling to ischemic stroke.

Proc Natl Acad Sci U S A 2008 Mar 17;105(12):4856-61. Epub 2008 Mar 17.

Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.0709867105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290794PMC
March 2008

Adiponectin prevents cerebral ischemic injury through endothelial nitric oxide synthase dependent mechanisms.

Circulation 2008 Jan 24;117(2):216-23. Epub 2007 Dec 24.

Stroke and Neurovascular Regulation Laboratory, Boston University School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.107.725044DOI Listing
January 2008

Blood vessels, migraine, and stroke.

Stroke 2007 Dec 25;38(12):3117-8. Epub 2007 Oct 25.

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http://dx.doi.org/10.1161/STROKEAHA.107.495770DOI Listing
December 2007

Genes, proteases, cortical spreading depression and migraine: impact on pathophysiology and treatment.

Funct Neurol 2007 Jul-Sep;22(3):133-6

Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.

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November 2007

MR contrast probes that trace gene transcripts for cerebral ischemia in live animals.

FASEB J 2007 Sep 3;21(11):3004-15. Epub 2007 May 3.

AA Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1096/fj.07-8203comDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657320PMC
September 2007

Age-dependent cerebrovascular dysfunction in a transgenic mouse model of cerebral amyloid angiopathy.

Brain 2007 Sep 16;130(Pt 9):2310-9. Epub 2007 Jul 16.

Stroke and Neurovascular Regulation Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1093/brain/awm156DOI Listing
September 2007

Cortical spreading depression and estrogen.

Headache 2007 Sep;47 Suppl 2:S79-85

Department of Radiology, Stroke and Neurovascular Regulation Laboratory, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1111/j.1526-4610.2007.00818.xDOI Listing
September 2007

Normobaric hyperoxia improves cerebral blood flow and oxygenation, and inhibits peri-infarct depolarizations in experimental focal ischaemia.

Brain 2007 Jun 27;130(Pt 6):1631-42. Epub 2007 Apr 27.

Stroke and Neurovascular Regulation Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1093/brain/awm071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023418PMC
June 2007

Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms.

J Cereb Blood Flow Metab 2007 May 11;27(5):998-1009. Epub 2006 Oct 11.

Department of Radiology, Stroke and Neurovascular Regulation Laboratory, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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http://journals.sagepub.com/doi/10.1038/sj.jcbfm.9600406
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http://dx.doi.org/10.1038/sj.jcbfm.9600406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614438PMC
May 2007

The 2006 Thomas Willis lecture: the adventures of a translational researcher in stroke and migraine.

Stroke 2007 May 5;38(5):1645-51. Epub 2007 Apr 5.

Department of Radiology, Neuroscience Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1161/STROKEAHA.107.483941DOI Listing
May 2007

Pathophysiology of headache--past and present.

Headache 2007 Apr;47 Suppl 1:S58-63

Harvard-MIT Division of Health Science and Technology, Cambridge, MA, USA.

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http://dx.doi.org/10.1111/j.1526-4610.2007.00678.xDOI Listing
April 2007

Sonic hedgehog inversely regulates the expression of angiopoietin-1 and angiopoietin-2 in fibroblasts.

Int J Mol Med 2007 Mar;19(3):445-51

Stroke and Neurovascular Regulation Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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March 2007

fMRI of delayed albumin treatment during stroke recovery in rats: implication for fast neuronal habituation in recovering brains.

J Cereb Blood Flow Metab 2007 Jan 17;27(1):142-53. Epub 2006 May 17.

Athinoula Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1038/sj.jcbfm.9600317DOI Listing
January 2007

Rapid nongenomic actions of thyroid hormone.

Proc Natl Acad Sci U S A 2006 Sep 11;103(38):14104-9. Epub 2006 Sep 11.

Vascular Medicine Research, Brigham and Women's Hospital and Harvard Medical School, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1073/pnas.0601600103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1599919PMC
September 2006

Vasoconstrictive neurovascular coupling during focal ischemic depolarizations.

J Cereb Blood Flow Metab 2006 Aug 7;26(8):1018-30. Epub 2005 Dec 7.

Stroke and Neurovascular Regulation Laboratory, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1038/sj.jcbfm.9600252DOI Listing
August 2006

New insights into migraine pathophysiology.

Curr Opin Neurol 2006 Jun;19(3):294-8

Department of Neurology, Hospital Ruber Internacional, Madrid, Spain.

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http://dx.doi.org/10.1097/01.wco.0000227041.23694.5cDOI Listing
June 2006

Cortical spreading depression confounds concentration-dependent pial arteriolar dilation during N-methyl-D-aspartate superfusion.

Am J Physiol Heart Circ Physiol 2006 May 18;290(5):H1837-41. Epub 2005 Nov 18.

Stroke and Neurovascular Regulation Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://www.physiology.org/doi/10.1152/ajpheart.01102.2005
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May 2006

Traumatic brain injury in mice deficient in Bid: effects on histopathology and functional outcome.

J Cereb Blood Flow Metab 2006 May;26(5):625-33

Neuroscience Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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http://journals.sagepub.com/doi/10.1038/sj.jcbfm.9600258
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May 2006

Suppression of cortical spreading depression in migraine prophylaxis.

Ann Neurol 2006 Apr;59(4):652-61

Stroke and Neurovascular Regulation Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1002/ana.20778DOI Listing
April 2006

The dynamics of statins: from event prevention to neuroprotection.

Stroke 2006 Feb 12;37(2):294-6. Epub 2006 Jan 12.

Department of Neurology, Stroke Centre, Denis Diderot University and Medical School, Bichat Hospital, Paris, France.

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https://www.ahajournals.org/doi/10.1161/01.STR.0000201856.90
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http://dx.doi.org/10.1161/01.STR.0000201856.90105.abDOI Listing
February 2006

Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection.

Stroke 2005 Oct 1;36(10):2251-7. Epub 2005 Sep 1.

Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1161/01.STR.0000181077.84981.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633591PMC
October 2005

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia.

Proc Natl Acad Sci U S A 2005 Aug 15;102(34):12005-10. Epub 2005 Aug 15.

Howard Hughes Medical Institute and Dana-Farber Cancer Institute, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0505294102
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1189333PMC
August 2005

Advances in stroke neuroprotection: hyperoxia and beyond.

Neuroimaging Clin N Am 2005 Aug;15(3):697-720, xii-xiii

Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.nic.2005.08.014DOI Listing
August 2005

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.

Nat Chem Biol 2005 Jul 29;1(2):112-9. Epub 2005 May 29.

Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nchembio711DOI Listing
July 2005

Protective effects of statins involving both eNOS and tPA in focal cerebral ischemia.

J Cereb Blood Flow Metab 2005 Jun;25(6):722-9

Neuroprotection Research Laboratory, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, 02129, USA.

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http://dx.doi.org/10.1038/sj.jcbfm.9600070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742229PMC
June 2005

Neuroprotection by IL-10-producing MOG CD4+ T cells following ischemic stroke.

J Neurol Sci 2005 Jun;233(1-2):125-32

Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.jns.2005.03.022DOI Listing
June 2005

The pathophysiology of migraine: year 2005.

J Headache Pain 2005 Jun 13;6(3):105-11. Epub 2005 May 13.

Headache Centre, IRCCS Santa Lucia Foundation, Via Ardeatina 306, I-00179, Rome, Italy.

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https://thejournalofheadacheandpain.biomedcentral.com/articl
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http://dx.doi.org/10.1007/s10194-005-0165-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3451639PMC
June 2005

Migraine as an inflammatory disorder.

Neurology 2005 May;64(10 Suppl 2):S9-15

Radiology Department, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1212/wnl.64.10_suppl_2.s9DOI Listing
May 2005