Michael A Dyer

Michael A Dyer

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Michael A Dyer

Michael A Dyer

Publications by authors named "Michael A Dyer"

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Optimal sequencing of chemoradiotherapy for locally advanced laryngeal cancer.

Laryngoscope 2019 Oct 9;129(10):2313-2320. Epub 2019 Jan 9.

Department of Radiation Oncology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts, U.S.A.

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http://dx.doi.org/10.1002/lary.27771DOI Listing
October 2019

Comparing surgical and nonsurgical larynx-preserving treatments with total laryngectomy for locally advanced laryngeal cancer.

Cancer 2019 Oct 17;125(19):3367-3377. Epub 2019 Jun 17.

Department of Radiation Oncology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts.

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http://dx.doi.org/10.1002/cncr.32292DOI Listing
October 2019

Interleukin-15 Enhances Anti-GD2 Antibody-Mediated Cytotoxicity in an Orthotopic PDX Model of Neuroblastoma.

Clin Cancer Res 2019 Aug 27. Epub 2019 Aug 27.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital

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http://dx.doi.org/10.1158/1078-0432.CCR-19-1045DOI Listing
August 2019

Nucleome Dynamics during Retinal Development.

Neuron 2019 Aug 21. Epub 2019 Aug 21.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38163, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.08.002DOI Listing
August 2019

Correction to: Imaging features of immune-mediated genitourinary disease.

Neurochem Res 2019 Jul;44(7):1780

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.

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http://link.springer.com/10.1007/s11064-019-02811-7
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http://dx.doi.org/10.1007/s11064-019-02811-7DOI Listing
July 2019

Development and Calibration of a Mathematical Model of Anal Carcinogenesis for High-Risk HIV-Infected Men.

J Acquir Immune Defic Syndr 2018 09;79(1):10-19

Department of Health Policy and Management, Center for Health Decision Science, Harvard T.H. Chan School of Public Health, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0000000000001727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092220PMC
September 2018

Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses.

Cancer Cell 2018 09 23;34(3):411-426.e19. Epub 2018 Aug 23.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, MS 323, Memphis, TN 38105-3678, USA; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38105, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158019PMC
September 2018

The role of interleukin-2, all-trans retinoic acid, and natural killer cells: surveillance mechanisms in anti-GD2 antibody therapy in neuroblastoma.

Cancer Immunol Immunother 2018 Apr 11;67(4):615-626. Epub 2018 Jan 11.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1007/s00262-017-2108-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862751PMC
April 2018

Retinal Cell Type DNA Methylation and Histone Modifications Predict Reprogramming Efficiency and Retinogenesis in 3D Organoid Cultures.

Cell Rep 2018 03;22(10):2601-2614

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38163, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.01.075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872828PMC
March 2018

Performance of a docking/molecular dynamics protocol for virtual screening of nutlin-class inhibitors of Mdmx.

J Mol Graph Model 2017 06 24;74:54-60. Epub 2017 Feb 24.

Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmgm.2017.02.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508530PMC
June 2017

The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis.

Neuron 2017 May;94(3):550-568.e10

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA; Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.04.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508517PMC
May 2017

ATRX and DAXX: Mechanisms and Mutations.

Cold Spring Harb Perspect Med 2017 Mar 1;7(3). Epub 2017 Mar 1.

Departments of Oncological Sciences and Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York 10029.

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http://dx.doi.org/10.1101/cshperspect.a026567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334245PMC
March 2017

Biomedicine: An eye on retinal recovery.

Authors:
Michael A Dyer

Nature 2016 12 30;540(7633):350-351. Epub 2016 Nov 30.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA. He is also in the Department of Ophthalmology, University of Tennessee Health Sciences Center, Memphis, and the Howard Hughes Medical Institute.

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http://dx.doi.org/10.1038/nature20487DOI Listing
December 2016

Progress in Small Molecule Therapeutics for the Treatment of Retinoblastoma.

Mini Rev Med Chem 2016 ;16(6):430-54

Department of Chemical Biology and Therapeutics, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509337PMC
http://dx.doi.org/10.2174/1389557515666150722100610DOI Listing
November 2016

Lessons from Retinoblastoma: Implications for Cancer, Development, Evolution, and Regenerative Medicine.

Authors:
Michael A Dyer

Trends Mol Med 2016 Oct 23;22(10):863-876. Epub 2016 Aug 23.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048577PMC
http://dx.doi.org/10.1016/j.molmed.2016.07.010DOI Listing
October 2016

Reprogramming of mouse retinal neurons and standardized quantification of their differentiation in 3D retinal cultures.

Nat Protoc 2016 Oct 15;11(10):1955-1976. Epub 2016 Sep 15.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1038/nprot.2016.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530375PMC
October 2016

Genetic and Epigenetic Discoveries in Human Retinoblastoma.

Crit Rev Oncog 2015 ;20(3-4):217-25

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee; Howard Hughes Medical Institute, Chevy Chase, Maryland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458782PMC
June 2016

ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment.

Epigenetics 2016 06 30;11(6):398-414. Epub 2016 Mar 30.

a Departments of Oncological Sciences and Dermatology , Icahn School of Medicine at Mount Sinai , New York , NY , USA.

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http://dx.doi.org/10.1080/15592294.2016.1169351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939920PMC
June 2016

Stem Cells Expand Insights into Human Brain Evolution.

Authors:
Michael A Dyer

Cell Stem Cell 2016 Apr;18(4):425-6

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.03.017DOI Listing
April 2016

The Childhood Solid Tumor Network: A new resource for the developmental biology and oncology research communities.

Dev Biol 2016 Mar 9;411(2):287-293. Epub 2015 Jun 9.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2015.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600003PMC
March 2016

Monitoring Ligand-Induced Protein Ordering in Drug Discovery.

J Mol Biol 2016 Mar 23;428(6):1290-1303. Epub 2016 Jan 23.

Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Sciences Center, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2016.01.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826315PMC
March 2016

Preclinical Models Provide Scientific Justification and Translational Relevance for Moving Novel Therapeutics into Clinical Trials for Pediatric Cancer.

Cancer Res 2015 Dec 1;75(24):5176-5186. Epub 2015 Dec 1.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, 38105, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-1308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681628PMC
December 2015

Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma.

Development 2015 Dec;142(23):4092-106

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38163, USA Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA

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http://dev.biologists.org/content/develop/142/23/4092.full.p
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http://dev.biologists.org/cgi/doi/10.1242/dev.124800
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http://dx.doi.org/10.1242/dev.124800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712833PMC
December 2015

Development and characterization of a human orthotopic neuroblastoma xenograft.

Dev Biol 2015 Nov 9;407(2):344-55. Epub 2015 Apr 9.

Department of Developmental Neurobiology, St. Jude Children׳s Research Hospital, Memphis, TN 38105, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00121606150006
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http://dx.doi.org/10.1016/j.ydbio.2015.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995597PMC
November 2015

Genetically engineered mouse and orthotopic human tumor xenograft models of retinoblastoma.

Methods Mol Biol 2015 ;1267:307-17

Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105-3678, USA.

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http://dx.doi.org/10.1007/978-1-4939-2297-0_15DOI Listing
September 2015

TNF Counterbalances the Emergence of M2 Tumor Macrophages.

Cell Rep 2015 Sep 10;12(11):1902-14. Epub 2015 Sep 10.

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.08.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581986PMC
September 2015

Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma.

Clin Cancer Res 2015 Jul 10;21(14):3216-29. Epub 2015 Apr 10.

St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia. Department of Medicine, St. Vincent's Hospital, University of Melbourne, Fitzroy, Victoria, Australia. ACRF Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-3026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506243PMC
July 2015

Quantification of Retinogenesis in 3D Cultures Reveals Epigenetic Memory and Higher Efficiency in iPSCs Derived from Rod Photoreceptors.

Cell Stem Cell 2015 Jul;17(1):101-15

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38163, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2015.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547539PMC
July 2015

Genetics and epigenetics of human retinoblastoma.

Annu Rev Pathol 2015 ;10:547-62

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105; email:

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http://dx.doi.org/10.1146/annurev-pathol-012414-040259DOI Listing
June 2015

CONSERTING: integrating copy-number analysis with structural-variation detection.

Nat Methods 2015 Jun 4;12(6):527-30. Epub 2015 May 4.

1] Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. [2] Pediatric Cancer Genome Project, St. Jude Children's Research Hospital and Washington University School of Medicine, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1038/nmeth.3394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591043PMC
June 2015

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis.

Nat Genet 2015 Jun 11;47(6):615-24. Epub 2015 May 11.

1] Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA. [2] Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota, USA. [3] Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA. [4] Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1038/ng.3293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767150PMC
June 2015

Post-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cells.

EMBO J 2014 Oct 6;33(19):2201-15. Epub 2014 Aug 6.

Massachusetts General Hospital Cancer Center and Harvard Medical School Laboratory of Molecular Oncology, Charlestown, MA, USA

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http://dx.doi.org/10.15252/embj.201488057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282507PMC
October 2014

Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression.

Oncotarget 2014 Oct;5(20):9594-608

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA. Department of Human Molecular Genetics and Biochemistry, Tel-Aviv University, Tel Aviv, Israel. Howard Hughes Medical Institute, Chevy Chase, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259422PMC
http://dx.doi.org/10.18632/oncotarget.2468DOI Listing
October 2014

The ATRX cDNA is prone to bacterial IS10 element insertions that alter its structure.

Springerplus 2014 2;3:222. Epub 2014 May 2.

Instituto de Fisiología Celular, Departamento de Genética Molecular, Universidad Nacional Autónoma de México, Ciudad Universitaria, México DF, México.

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021028/
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https://www.researchgate.net/publication/312141402_ATRX_and_
Web Search
http://springerplus.springeropen.com/articles/10.1186/2193-1
Publisher Site
http://dx.doi.org/10.1186/2193-1801-3-222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021028PMC
May 2014

Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm.

Stem Cells 2014 Jan;32(1):191-203

Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA; The Tisch Cancer Institute, Mount Sinai School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1002/stem.1536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908821PMC
January 2014

Neuroblastoma: developmental biology, cancer genomics and immunotherapy.

Nat Rev Cancer 2013 Jun;13(6):397-411

Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1038/nrc3526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386662PMC
June 2013

An Open Trial of Relapse Prevention Therapy for Smokers With Schizophrenia.

J Dual Diagn 2013 ;9(1):87-93

Schizophrenia Program, Massachusetts General Hospital and Harvard Medical School ; Center for Addiction Medicine, Massachusetts General Hospital and Harvard Medical School ; Department of Psychiatry of the Massachusetts General Hospital and Harvard Medical School.

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http://dx.doi.org/10.1080/15504263.2012.749559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671354PMC
January 2013

Retinoblastoma (Rb) regulates laminar dendritic arbor reorganization in retinal horizontal neurons.

Proc Natl Acad Sci U S A 2011 Dec 12;108(52):21111-6. Epub 2011 Dec 12.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1073/pnas.1108141108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248513PMC
December 2011

Targeting the p53 pathway in retinoblastoma with subconjunctival Nutlin-3a.

Cancer Res 2011 Jun 22;71(12):4205-13. Epub 2011 Apr 22.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105-2794, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-0058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116943PMC
June 2011

Automated tracing of horizontal neuron processes during retinal development.

Neurochem Res 2011 Apr 8;36(4):583-93. Epub 2011 Jan 8.

Measurement Science and Systems Engineering Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA.

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http://dx.doi.org/10.1007/s11064-010-0390-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097172PMC
April 2011

Oncogenesis and the development of treatments. Preface.

Authors:
Michael A Dyer

Curr Top Dev Biol 2011 ;94:xiii-xiv

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http://dx.doi.org/10.1016/B978-0-12-380916-2.00011-5DOI Listing
April 2011

Childhood cancer and developmental biology a crucial partnership.

Curr Top Dev Biol 2011 ;94:1-13

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1016/B978-0-12-380916-2.00001-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551576PMC
April 2011

Subconjunctival carboplatin and systemic topotecan treatment in preclinical models of retinoblastoma.

Cancer 2011 Jan 3;117(2):421-34. Epub 2010 Sep 3.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105-2794, USA.

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http://dx.doi.org/10.1002/cncr.25574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000447PMC
January 2011

Retinal progenitor cells, differentiation, and barriers to cell cycle reentry.

Curr Top Dev Biol 2010 ;93:175-88

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1016/B978-0-12-385044-7.00006-0DOI Listing
January 2011

Changes in retinoblastoma cell adhesion associated with optic nerve invasion.

Mol Cell Biol 2009 Dec 28;29(23):6268-82. Epub 2009 Sep 28.

Department of Developmental Neurobiology, MS 323, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1128/MCB.00374-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786692PMC
December 2009

Mutations and cancer: one or two historical perspectives?

Lancet Oncol 2009 Aug;10(8):834

Developmental Neurobiology, St Jude Children's Research Hospital Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/S1470-2045(09)70071-3DOI Listing
August 2009

In their own words: interviews with Cell Cycle. The first knockout mouse model of retinoblastoma.

Authors:
Michael A Dyer

Cell Cycle 2009 Jul 15;8(14):2145. Epub 2009 Jul 15.

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http://dx.doi.org/10.4161/cc.8.14.9068DOI Listing
July 2009

Developmental sources of conservation and variation in the evolution of the primate eye.

Proc Natl Acad Sci U S A 2009 Jun 18;106(22):8963-8. Epub 2009 May 18.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1073/pnas.0901484106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690025PMC
June 2009

AAV-mediated local delivery of interferon-beta for the treatment of retinoblastoma in preclinical models.

Neuromolecular Med 2009 22;11(1):43-52. Epub 2009 Mar 22.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://link.springer.com/10.1007/s12017-009-8059-0
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http://dx.doi.org/10.1007/s12017-009-8059-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725441PMC
April 2009

Cells previously identified as retinal stem cells are pigmented ciliary epithelial cells.

Proc Natl Acad Sci U S A 2009 Apr 3;106(16):6685-90. Epub 2009 Apr 3.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1073/pnas.0901596106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672506PMC
April 2009

A new model of tumor susceptibility following tumor suppressor gene inactivation.

Cell Cycle 2008 Mar 11;7(6):735-40. Epub 2008 Jan 11.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.4161/cc.7.6.5612DOI Listing
March 2008

The effects of transdermal nicotine on cognition in nonsmokers with schizophrenia and nonpsychiatric controls.

Neuropsychopharmacology 2008 Feb 18;33(3):480-90. Epub 2007 Apr 18.

The Schizophrenia Program of the Massachusetts General Hospital, Boston, MA 02114, USA.

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http://www.nature.com/articles/1301423
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http://dx.doi.org/10.1038/sj.npp.1301423DOI Listing
February 2008

Statistical analysis of data from retroviral clonal experiments in the developing retina.

Brain Res 2008 Feb 11;1192:178-85. Epub 2007 Sep 11.

Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/j.brainres.2007.08.074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699588PMC
February 2008

N-myc coordinates retinal growth with eye size during mouse development.

Genes Dev 2008 Jan;22(2):179-93

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1101/gad.1608008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192753PMC
January 2008

Preparation and square wave electroporation of retinal explant cultures.

Nat Protoc 2006 ;1(6):2710-8

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1038/nprot.2006.454DOI Listing
November 2007

Targeting MDM2 and MDMX in retinoblastoma.

Curr Cancer Drug Targets 2007 Nov;7(7):689-95

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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November 2007

Retinoblastoma: from the two-hit hypothesis to targeted chemotherapy.

Cancer Res 2007 Aug;67(16):7547-50

Department of Embryology, Carnegie Institution, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-0276DOI Listing
August 2007

Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype.

Genes Dev 2007 Jul 12;21(14):1731-46. Epub 2007 Jul 12.

Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.

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http://dx.doi.org/10.1101/gad.1556607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920168PMC
July 2007

Neuronal differentiation and synaptogenesis in retinoblastoma.

Cancer Res 2007 Mar;67(6):2701-11

Department of Ophthalmology, College of Medicine, University of Tennessee Health Sciences Center, Memphis, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3754DOI Listing
March 2007

MDMX: from bench to bedside.

J Cell Sci 2007 Feb;120(Pt 3):371-8

Laboratory For Molecular Cancer Biology, Flanders Interuniversity Institute for Biotechnology (VIB), University of Ghent, B-9052 Ghent, Belgium.

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http://dx.doi.org/10.1242/jcs.03362DOI Listing
February 2007

Mosaic deletion of Rb arrests rod differentiation and stimulates ectopic synaptogenesis in the mouse retina.

J Comp Neurol 2006 Sep;498(1):112-28

Department of Ophthalmology, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1002/cne.21059DOI Listing
September 2006

Glutamate regulates retinal progenitors cells proliferation during development.

Eur J Neurosci 2006 Aug 21;24(4):969-80. Epub 2006 Aug 21.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1111/j.1460-9568.2006.04966.xDOI Listing
August 2006

Compensation by tumor suppressor genes during retinal development in mice and humans.

BMC Biol 2006 May 3;4:14. Epub 2006 May 3.

Department of Developmental Neurobiology, St, Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1186/1741-7007-4-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1481602PMC
May 2006

An E2F binding-deficient Rb1 protein partially rescues developmental defects associated with Rb1 nullizygosity.

Mol Cell Biol 2006 Feb;26(4):1527-37

Department of Pharmacology & Therapeutics, Roswell Park Cancer Institute, Elm & Carlton Streets, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.1128/MCB.26.4.1527-1537.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1367194PMC
February 2006

Perspective: new genetic tools for studying retinal development and disease.

Vis Neurosci 2005 Sep-Oct;22(5):553-60

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis.

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http://dx.doi.org/10.1017/S0952523805225026DOI Listing
January 2006

Use of preclinical models to improve treatment of retinoblastoma.

PLoS Med 2005 Oct 25;2(10):e332. Epub 2005 Oct 25.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.

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http://dx.plos.org/10.1371/journal.pmed.0020332
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http://dx.doi.org/10.1371/journal.pmed.0020332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1261510PMC
October 2005

Topotecan combination chemotherapy in two new rodent models of retinoblastoma.

Clin Cancer Res 2005 Oct;11(20):7569-78

Department of Developmental Neurobiology and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-0849DOI Listing
October 2005

Regulation of proliferation during central nervous system development.

Semin Cell Dev Biol 2005 Jun;16(3):407-21

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105-2794, USA.

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http://dx.doi.org/10.1016/j.semcdb.2005.02.012DOI Listing
June 2005

The search for the retinoblastoma cell of origin.

Nat Rev Cancer 2005 Feb;5(2):91-101

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://www.nature.com/doifinder/10.1038/nrc1545
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http://dx.doi.org/10.1038/nrc1545DOI Listing
February 2005

Retinal degeneration in Aipl1-deficient mice: a new genetic model of Leber congenital amaurosis.

Brain Res Mol Brain Res 2004 Dec;132(2):208-20

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/j.molbrainres.2004.10.011DOI Listing
December 2004