Micah J McCauley

Micah J McCauley

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Micah J McCauley

Micah J McCauley

Publications by authors named "Micah J McCauley"

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31Publications

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Specific Nucleic Acid Chaperone Activity of HIV-1 Nucleocapsid Protein Deduced from Hairpin Unfolding.

Methods Mol Biol 2020 ;2106:59-88

Department of Physics, Northeastern University, Boston, MA, USA.

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http://dx.doi.org/10.1007/978-1-0716-0231-7_4DOI Listing
January 2020

Constructing Free Energy Landscapes of Nucleic Acid Hairpin Unfolding.

Methods Mol Biol 2018 ;1811:315-332

Department of Physics, Northeastern University, Boston, MA, USA.

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http://dx.doi.org/10.1007/978-1-4939-8582-1_21DOI Listing
March 2019

The elusive keys to nucleic acid stability: Comment on "DNA melting and energetics of the double helix" by Alexander Vologodskii and Maxim D. Frank-Kamenetskii.

Phys Life Rev 2018 08 9;25:37-39. Epub 2018 Feb 9.

Department of Physics, Northeastern University, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.plrev.2018.02.002DOI Listing
August 2018

Single-molecule studies of high-mobility group B architectural DNA bending proteins.

Biophys Rev 2017 Feb 15;9(1):17-40. Epub 2016 Nov 15.

Department of Physics, Northeastern University, Boston, MA 02115 USA.

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http://dx.doi.org/10.1007/s12551-016-0236-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331113PMC
February 2017

Targeted binding of nucleocapsid protein transforms the folding landscape of HIV-1 TAR RNA.

Proc Natl Acad Sci U S A 2015 Nov 19;112(44):13555-60. Epub 2015 Oct 19.

Department of Physics, Northeastern University, Boston, MA 02115;

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http://dx.doi.org/10.1073/pnas.1510100112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640786PMC
November 2015

A ruthenium dimer complex with a flexible linker slowly threads between DNA bases in two distinct steps.

Nucleic Acids Res 2015 Oct 13;43(18):8856-67. Epub 2015 Sep 13.

Department of Physics, Northeastern University, Boston, MA 02115, USA

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http://dx.doi.org/10.1093/nar/gkv864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605314PMC
October 2015

Mechanical properties of base-modified DNA are not strictly determined by base stacking or electrostatic interactions.

Biophys J 2014 Jul;107(2):448-459

Department of Biochemistry and Molecular Biology and Mayo Graduate School, Mayo Clinic College of Medicine, Rochester, Minnesota. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2014.04.066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104048PMC
July 2014

Differential contribution of basic residues to HIV-1 nucleocapsid protein's nucleic acid chaperone function and retroviral replication.

Nucleic Acids Res 2014 Feb 28;42(4):2525-37. Epub 2013 Nov 28.

Department of Physics, Northeastern University, Boston, MA 02115, USA, Department of Chemistry and Biochemistry, Center for RNA Biology, and Center for Retrovirus Research, The Ohio State University, Columbus, OH 43210, USA, AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA and Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1093/nar/gkt1227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936775PMC
February 2014

Single-molecule kinetics reveal microscopic mechanism by which High-Mobility Group B proteins alter DNA flexibility.

Nucleic Acids Res 2013 Jan 9;41(1):167-81. Epub 2012 Nov 9.

Department of Physics, Northeastern University, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/nar/gks1031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592474PMC
January 2013

Force spectroscopy reveals the DNA structural dynamics that govern the slow binding of Actinomycin D.

Nucleic Acids Res 2012 Jun 10;40(11):4925-32. Epub 2012 Feb 10.

Department of Physics, Northeastern University, Boston, MA-02115, USA.

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http://dx.doi.org/10.1093/nar/gks069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367174PMC
June 2012

Basic N-terminus of yeast Nhp6A regulates the mechanism of its DNA flexibility enhancement.

J Mol Biol 2012 Feb 13;416(1):10-20. Epub 2011 Dec 13.

Department of Physics, Northeastern University, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.jmb.2011.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280093PMC
February 2012

Measuring DNA-protein binding affinity on a single molecule using optical tweezers.

Methods Mol Biol 2011 ;749:305-15

Department of Physics, Northeastern University, Boston, MA, USA.

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http://dx.doi.org/10.1007/978-1-61779-142-0_21DOI Listing
December 2011

Single-molecule biophysics: untying a nanoscale knot.

Nat Chem 2011 Sep 23;3(10):754-5. Epub 2011 Sep 23.

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http://dx.doi.org/10.1038/nchem.1159DOI Listing
September 2011

Biophysical characterization of DNA binding from single molecule force measurements.

Phys Life Rev 2010 Sep 4;7(3):299-341. Epub 2010 Jun 4.

Department of Physics, Northeastern University, 111 Dana Research Center, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.plrev.2010.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930095PMC
September 2010

Peeling back the mystery of DNA overstretching.

Proc Natl Acad Sci U S A 2009 Oct 21;106(43):18047-8. Epub 2009 Oct 21.

Department of Physics, Northeastern University, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.0910269106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775292PMC
October 2009

Optical tweezers experiments resolve distinct modes of DNA-protein binding.

Biopolymers 2009 Apr;91(4):265-82

Department of Physics and Center for Interdisciplinary Research on Complex Systems, Northeastern University, 111 Dana Research Center, Boston, MA 02115, USA.

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http://doi.wiley.com/10.1002/bip.21123
Publisher Site
http://dx.doi.org/10.1002/bip.21123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753391PMC
April 2009

Mechanism of DNA flexibility enhancement by HMGB proteins.

Nucleic Acids Res 2009 Mar 7;37(4):1107-14. Epub 2009 Jan 7.

Department of Physics, Northeastern University, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/nar/gkn1011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651801PMC
March 2009

Distinct double- and single-stranded DNA binding of E. coli replicative DNA polymerase III alpha subunit.

ACS Chem Biol 2008 Sep 25;3(9):577-87. Epub 2008 Jul 25.

Department of Physics, Northeastern University, Boston, Massachusetts, 02115, USA.

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http://dx.doi.org/10.1021/cb8001107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665888PMC
September 2008

DNA overstretching in the presence of glyoxal: structural evidence of force-induced DNA melting.

Biophys J 2008 Aug 18;95(3):1248-55. Epub 2008 Apr 18.

Department of Physics, Northeastern University, Boston, Massachusetts 02115, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00063495087019
Publisher Site
http://dx.doi.org/10.1529/biophysj.108.132688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2479620PMC
August 2008

Mechanically manipulating the DNA threading intercalation rate.

J Am Chem Soc 2008 Mar 1;130(12):3752-3. Epub 2008 Mar 1.

Department of Physics, Northeastern University, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1021/ja711303pDOI Listing
March 2008

HMGB binding to DNA: single and double box motifs.

J Mol Biol 2007 Dec 29;374(4):993-1004. Epub 2007 Sep 29.

Department of Physics, Northeastern University, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.jmb.2007.09.073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2117627PMC
December 2007

Quantifying force-dependent and zero-force DNA intercalation by single-molecule stretching.

Nat Methods 2007 Jun 29;4(6):517-22. Epub 2007 Apr 29.

Department of Physics, Northeastern University, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nmeth1044DOI Listing
June 2007

Mechanisms of DNA binding determined in optical tweezers experiments.

Biopolymers 2007 Feb;85(2):154-68

Department of Physics, Northeastern University, 111 Dana Research Center, Boston, MA 02115, USA.

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http://dx.doi.org/10.1002/bip.20622DOI Listing
February 2007

Mapping the phase diagram of single DNA molecule force-induced melting in the presence of ethidium.

Phys Rev Lett 2005 Oct 6;95(15):158102. Epub 2005 Oct 6.

Department of Physics, Northeastern University, 111 Dana Research Center, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1103/PhysRevLett.95.158102DOI Listing
October 2005