Publications by authors named "Micah D Gearhart"

30Publications

Dux facilitates post-implantation development, but is not essential for zygotic genome activation.

Biol Reprod 2020 Sep 30. Epub 2020 Sep 30.

Lillehei Heart Institute.

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http://dx.doi.org/10.1093/biolre/ioaa179DOI Listing
September 2020

OFCD syndrome and extraembryonic defects are revealed by conditional mutation of the Polycomb-group repressive complex 1.1 (PRC1.1) gene BCOR.

Dev Biol 2020 Dec 18;468(1-2):110-132. Epub 2020 Jul 18.

Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN, 55455, USA; Developmental Biology Center, University of Minnesota, Minneapolis, MN, 55455, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, 55455, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2020.06.013DOI Listing
December 2020

Structure and Role of BCOR PUFD in Noncanonical PRC1 Assembly and Disease.

Biochemistry 2020 Jul 10;59(29):2718-2728. Epub 2020 Jul 10.

Department of Biochemistry and Molecular Genetics, Midwestern University, 19555 North 59th Avenue, Glendale, Arizona 85308, United States.

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http://dx.doi.org/10.1021/acs.biochem.0c00285DOI Listing
July 2020

Insights into the Involvement of Spliceosomal Mutations in Myelodysplastic Disorders from Analysis of SACY-1/DDX41 in .

Genetics 2020 04 14;214(4):869-893. Epub 2020 Feb 14.

Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455

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http://dx.doi.org/10.1534/genetics.119.302973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153925PMC
April 2020

BCL6 corepressor contributes to Th17 cell formation by inhibiting Th17 fate suppressors.

J Exp Med 2019 06 3;216(6):1450-1464. Epub 2019 May 3.

Department of Microbiology and Immunology, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN

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http://www.jem.org/lookup/doi/10.1084/jem.20182376
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http://dx.doi.org/10.1084/jem.20182376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547868PMC
June 2019

AP-1/miR-200a regulate the pro-regenerative glial cell response during axolotl spinal cord regeneration.

Commun Biol 2019 6;2:91. Epub 2019 Mar 6.

Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN, 55455, USA.

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http://dx.doi.org/10.1038/s42003-019-0335-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403268PMC
April 2020

A Non-canonical BCOR-PRC1.1 Complex Represses Differentiation Programs in Human ESCs.

Cell Stem Cell 2018 02 11;22(2):235-251.e9. Epub 2018 Jan 11.

Department of Genetics, Yale University, New Haven, CT 06520, USA; Yale Stem Cell Center, Yale University, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797497PMC
February 2018

p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy.

Dis Model Mech 2017 10 28;10(10):1211-1216. Epub 2017 Jul 28.

Lillehei Heart Institute, University of Minnesota, 312 Church St. SE, Minneapolis, MN 55455, USA

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http://dx.doi.org/10.1242/dmm.030064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665455PMC
October 2017

Retinoic acid signaling is dispensable for somatic development and function in the mammalian ovary.

Dev Biol 2017 04 6;424(2):208-220. Epub 2017 Mar 6.

Department of Genetics, Cell Biology, and Development, and Developmental Biology Center, University of Minnesota, Minneapolis, MN 55455, USA; University of Minnesota Masonic Cancer Center, Minneapolis, MN 55455, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2017.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411265PMC
April 2017

KDM2B Recruitment of the Polycomb Group Complex, PRC1.1, Requires Cooperation between PCGF1 and BCORL1.

Structure 2016 Oct 25;24(10):1795-1801. Epub 2016 Aug 25.

Department of Biochemistry, Midwestern University, 19555 North 59(th) Avenue, Glendale, AZ 85308, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088048PMC
http://dx.doi.org/10.1016/j.str.2016.07.011DOI Listing
October 2016

DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes.

Nucleic Acids Res 2016 06 6;44(11):5161-73. Epub 2016 Mar 6.

Lillehei Heart Institute, University of Minnesota, 312 Church St. SE, Minneapolis, MN 55455, USA Department of Pediatrics, University of Minnesota, 312 Church St. SE, Minneapolis, MN 55455, USA

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http://dx.doi.org/10.1093/nar/gkw141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914088PMC
June 2016

A novel role for SALL4 during scar-free wound healing in axolotl.

NPJ Regen Med 2016 8;1. Epub 2016 Dec 8.

Department of Genetics, Cell Biology and Development, University of Minnesota, Minnesota, MN, USA.

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http://dx.doi.org/10.1038/npjregenmed.2016.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612448PMC
December 2016

Identification of Conserved and Novel MicroRNAs during Tail Regeneration in the Mexican Axolotl.

Int J Mol Sci 2015 Sep 11;16(9):22046-61. Epub 2015 Sep 11.

Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.3390/ijms160922046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613296PMC
September 2015

An ancient protein-DNA interaction underlying metazoan sex determination.

Nat Struct Mol Biol 2015 Jun 25;22(6):442-51. Epub 2015 May 25.

1] Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota, USA. [2] Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA. [3] Developmental Biology Center, University of Minnesota, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1038/nsmb.3032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476070PMC
June 2015

Cutting edge: Bcl6-interacting corepressor contributes to germinal center T follicular helper cell formation and B cell helper function.

J Immunol 2015 Jun 11;194(12):5604-8. Epub 2015 May 11.

Department of Microbiology and Immunology, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455; and

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http://dx.doi.org/10.4049/jimmunol.1500201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458443PMC
June 2015

Sexual cell-fate reprogramming in the ovary by DMRT1.

Curr Biol 2015 Mar 12;25(6):764-771. Epub 2015 Feb 12.

Department of Genetics, Cell Biology, and Development, Developmental Biology Center, and Masonic Cancer Center, University of Minnesota, 6-160 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455 USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09609822150006
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http://dx.doi.org/10.1016/j.cub.2015.01.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366330PMC
March 2015

The mammalian Doublesex homolog DMRT6 coordinates the transition between mitotic and meiotic developmental programs during spermatogenesis.

Development 2014 Oct;141(19):3662-71

Developmental Biology Center, Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455, USA University of Minnesota Masonic Cancer Center, Minneapolis, MN 55455, USA

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http://dev.biologists.org/content/develop/141/19/3662.full.p
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http://dev.biologists.org/cgi/doi/10.1242/dev.113936
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http://dx.doi.org/10.1242/dev.113936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197572PMC
October 2014

Structure of the polycomb group protein PCGF1 in complex with BCOR reveals basis for binding selectivity of PCGF homologs.

Structure 2013 Apr 21;21(4):665-71. Epub 2013 Mar 21.

Department of Biochemistry and CTRC, University of Texas Health Science Center at San Antonio, MSC 7760, 7703 Floyd Curl Drive, San Antonio, TX 78229-3990, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09692126130005
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http://dx.doi.org/10.1016/j.str.2013.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003909PMC
April 2013

Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets.

Mol Cell Biol 2006 Sep;26(18):6880-9

Department of Genetics, Cell Biology and Development, 6-160 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1128/MCB.00630-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592854PMC
September 2006

Inhibition of DNA binding by human estrogen-related receptor 2 and estrogen receptor alpha with minor groove binding polyamides.

Biochemistry 2005 Mar;44(11):4196-203

Department of Molecular Biology, The Scripps Research Institute, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1021/bi047872oDOI Listing
March 2005

Monomeric complex of human orphan estrogen related receptor-2 with DNA: a pseudo-dimer interface mediates extended half-site recognition.

J Mol Biol 2003 Apr;327(4):819-32

Department of Molecular Biology and Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/s0022-2836(03)00183-9DOI Listing
April 2003