Publications by authors named "Mi-Ae Park"

56Publications

Genome editing of CCR5 by CRISPR-Cas9 in Mauritian cynomolgus macaque embryos.

Sci Rep 2020 10 28;10(1):18457. Epub 2020 Oct 28.

Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA.

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October 2020

Inter-observer reproducibility and intra-observer repeatability in Tc-pyrophosphate scan interpretation for diagnosis of transthyretin cardiac amyloidosis.

J Nucl Cardiol 2020 Sep 11. Epub 2020 Sep 11.

Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, 75 Francis St, Boston, MA, 02115, USA.

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September 2020

Regional microglial activation in the substantia nigra is linked with fatigue in MS.

Neurol Neuroimmunol Neuroinflamm 2020 09 7;7(5). Epub 2020 Aug 7.

From the Partners MS Center (T.S., S.C., K.C., B.G., R.B., H.L.W.), Ann Romney Center for Neurological Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; PET Imaging Program in Neurologic Diseases (T.S., S.C., K.C.), Ann Romney Center for Neurological Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Functional Neuroimaging Laboratory (H.P., R.B., D.S.), Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Division of Nuclear Medicine and Molecular Imaging (S.D., M.-A.P., M.K.), Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Laboratory for Neuroimaging Research (R.C., S.T.), Ann Romney Center for Neurological Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Department of Medicine (S.H.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Ceretype Neuromedicine (E.S.)Department of Radiology (R.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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September 2020

Quantitative Bone-Avid Tracer SPECT/CT for Cardiac Amyloidosis: A Crucial Step Forward.

JACC Cardiovasc Imaging 2020 06;13(6):1364-1367

Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts.

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June 2020

Improved Quantification of Cardiac Amyloid Burden in Systemic Light Chain Amyloidosis: Redefining Early Disease?

JACC Cardiovasc Imaging 2020 06 13;13(6):1325-1336. Epub 2020 May 13.

Department of Medicine, Division of Cardiology, Cardiac Amyloidosis Program, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Department of Radiology, Division of Nuclear Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Department of Medicine and Radiology, CV Imaging Program, Cardiovascular Division, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:

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June 2020

Reproducibility and Repeatability of Assessment of Myocardial Light Chain Amyloidosis Burden Using F-Florbetapir PET/CT.

J Nucl Cardiol 2019 Nov 22. Epub 2019 Nov 22.

Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, 75 Francis St, Boston, MA, 02115, USA.

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November 2019

Image quality evaluation of ultrasound imaging systems: advanced B-modes.

J Appl Clin Med Phys 2019 Mar;20(3):115-124

Department of Radiology, Brigham and Women's Hospital & Harvard Medical School, Boston, MA, USA.

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March 2019

Genetic Engineering of Human Pluripotent Stem Cells Using PiggyBac Transposon System.

Curr Protoc Stem Cell Biol 2018 11 3;47(1):e63. Epub 2018 Oct 3.

National Primate Research Center, University of Wisconsin Graduate School, Madison.

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November 2018

Relative Apical Sparing of Myocardial Longitudinal Strain Is Explained by Regional Differences in Total Amyloid Mass Rather Than the Proportion of Amyloid Deposits.

JACC Cardiovasc Imaging 2019 07 15;12(7 Pt 1):1165-1173. Epub 2018 Aug 15.

Noninvasive Cardiovascular Imaging Program, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Division of Nuclear Medicine, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Amyloidosis Program, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

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July 2019

Activation of the Arterial Program Drives Development of Definitive Hemogenic Endothelium with Lymphoid Potential.

Cell Rep 2018 05;23(8):2467-2481

National Primate Research Center, University of Wisconsin Graduate School, 1220 Capitol Court, Madison, WI 53715, USA; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53707-7365, USA; Department of Pathology and Laboratory Medicine, University of Wisconsin Medical School, 600 Highland Avenue, Madison, WI 53792, USA. Electronic address:

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May 2018

Mbd2-CP2c loop drives adult-type globin gene expression and definitive erythropoiesis.

Nucleic Acids Res 2018 06;46(10):4933-4949

Department of Life Science and Research Institute of Natural Sciences, College of Natural Sciences, Hanyang University, Seoul 04763, Korea.

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June 2018

The roles of C-acetate PET/CT in predicting tumor differentiation and survival in patients with cerebral glioma.

Eur J Nucl Med Mol Imaging 2018 06 6;45(6):1012-1020. Epub 2018 Mar 6.

Department of Nuclear Medicine, Severance Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.

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June 2018

A human VE-cadherin-tdTomato and CD43-green fluorescent protein dual reporter cell line for study endothelial to hematopoietic transition.

Stem Cell Res 2016 09 13;17(2):401-405. Epub 2016 Sep 13.

Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA; Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI 53792, USA. Electronic address:

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September 2016

Introduction of a novel ultrahigh sensitivity collimator for brain SPECT imaging.

Med Phys 2016 Aug;43(8):4734

Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115.

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August 2016

Increased 18F-FDG Uptake on PET/CT is Associated With Poor Arterial and Portal Perfusion on Multiphase CT.

Clin Nucl Med 2016 Apr;41(4):296-301

From the Departments of *Nuclear Medicine and †Radiology, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea; ‡Program of Nanoscience and Technology, the Graduate School of Yonsei University College of Medicine, Seoul, Korea; and §Department of Radiology, Harvard Medical School, Brigham Women's Hospital, Boston, MA.

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April 2016

CCR5 Disruption in Induced Pluripotent Stem Cells Using CRISPR/Cas9 Provides Selective Resistance of Immune Cells to CCR5-tropic HIV-1 Virus.

Mol Ther Nucleic Acids 2015 Dec 15;4:e268. Epub 2015 Dec 15.

National Primate Research Center, University of Wisconsin Graduate School, Madison, Wisconsin, USA.

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December 2015

Investigation of imaging properties for submillimeter rectangular pinholes.

Med Phys 2015 Dec;42(12):6933-44

The Department of Radiology, The University of Pennsylvania, Philadelphia, Pennsylvania 19104.

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December 2015

18F-Florbetapir Binds Specifically to Myocardial Light Chain and Transthyretin Amyloid Deposits: Autoradiography Study.

Circ Cardiovasc Imaging 2015 Aug;8(8)

From the Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (M.-A.P., A.B., S.D., V.V., M.F.D., S.D.), Noninvasive Cardiovascular Imaging Program, Department of Medicine (Cardiology) and Radiology (V.V., M.F.D., S.D.), Cardiac Amyloidosis Program, Department of Medicine (R.F.P., R.H.F., S.D.), and Department of Pathology (R.F.P., D.H.H.), Brigham and Women's Hospital, Boston, MA.

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August 2015

Quantitative molecular imaging of cardiac amyloidosis: The journey has begun.

J Nucl Cardiol 2016 08 16;23(4):751-3. Epub 2015 Jul 16.

Division of Nuclear Medicine, Department of Radiology, Brigham and Women's Hospital, 70 Francis Street, Shapiro 5th Floor, Room 128, Boston, MA, 02115, USA.

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August 2016

mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation.

Cell Rep 2015 Jul 25;12(1):102-115. Epub 2015 Jun 25.

Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY 10065, USA; Division of Pulmonary and Critical Care Medicine, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address:

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July 2015

Approaches to reducing radiation dose from radionuclide myocardial perfusion imaging.

J Nucl Med 2015 Apr 12;56(4):592-9. Epub 2015 Mar 12.

Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, the Noninvasive Cardiovascular Imaging Program, Departments of Medicine (Cardiology) and Radiology, Brigham and Women's Hospital, Boston, Massachusetts.

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April 2015

Recovery and normalization of triple coincidences in PET.

Med Phys 2015 Mar;42(3):1398-410

Madrid-MIT M+Visión Consortium, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139.

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March 2015

Perceived sleep quality is associated with depression in a Korean elderly population.

Arch Gerontol Geriatr 2014 Sep-Oct;59(2):468-73. Epub 2014 May 2.

Department of Psychiatry, Ajou University School of Medicine, Suwon, Republic of Korea; Institute on Aging, Ajou University Medical Center, Suwon, Republic of Korea; Memory Impairment Center, Ajou University Hospital, Suwon, Republic of Korea. Electronic address:

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December 2014

Quantitative simultaneous 111In∕99mTc SPECT-CT of osteomyelitis.

Med Phys 2013 Aug;40(8):082501

Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Brigham and Women's Hospital, 75 Francis Street, Boston, Massachusetts 02115, USA.

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August 2013

PET∕CT imaging evidence of FUS-mediated (18)F-FDG uptake changes in rat brain.

Med Phys 2013 Mar;40(3):033501

Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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March 2013

Suppression and recovery of BRCA1-mediated transcription by HP1γ via modulation of promoter occupancy.

Nucleic Acids Res 2012 Dec 15;40(22):11321-38. Epub 2012 Oct 15.

Department of Molecular Science and Technology College of Natural Sciences Ajou University, Suwon, Korea.

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December 2012

Er:YAG laser pulse for small-dose splashback-free microjet transdermal drug delivery.

Opt Lett 2012 Sep;37(18):3894-6

Mechanical and Aerospace Engineering, Seoul National University, Seoul, South Korea.

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September 2012

Detection of murine post-pneumonectomy lung regeneration by 18FDG PET imaging.

EJNMMI Res 2012 Sep 21;2(1):48. Epub 2012 Sep 21.

Laboratory of Adaptive and Regenerative Biology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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September 2012

Improved regional activity quantitation in nuclear medicine using a new approach to correct for tissue partial volume and spillover effects.

IEEE Trans Med Imaging 2012 Feb 29;31(2):405-16. Epub 2011 Sep 29.

Department of Radiology, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115 USA.

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February 2012

ATM modulates transcription in response to histone deacetylase inhibition as part of its DNA damage response.

Exp Mol Med 2010 Mar;42(3):195-204

Department of Molecular Science and Technology, College of Natural Sciences, Ajou University, Suwon 443-749, Korea.

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March 2010

Design and fabrication of phantoms using stereolithography for small-animal imaging systems.

Mol Imaging Biol 2008 Sep 11;10(5):231-6. Epub 2008 Jun 11.

Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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September 2008

Adsorption of metallic radionuclides on plastic phantom walls.

Med Phys 2008 Apr;35(4):1606-10

Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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April 2008

Quantitative simultaneous In-111/Tc-99m planar imaging in a long-bone infection phantom.

Phys Med Biol 2007 Dec 5;52(24):7353-65. Epub 2007 Dec 5.

Department of Radiology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.

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December 2007

SUMO1 negatively regulates BRCA1-mediated transcription, via modulation of promoter occupancy.

Nucleic Acids Res 2008 Jan 19;36(1):263-83. Epub 2007 Nov 19.

Department of Biological Sciences & Department of Molecular Science and Technology Ajou University, Suwon, Korea.

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January 2008

Brain SPECT with short focal-length cone-beam collimation.

Med Phys 2005 Jul;32(7):2236-44

Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

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July 2005

Erythroid cell-specific alpha-globin gene regulation by the CP2 transcription factor family.

Mol Cell Biol 2005 Jul;25(14):6005-20

Department of Life Science and Research Institute for Natural Sciences, College of Natural Sciences, Hanyang University, Haengdang 17, Sungdong-gu, Seoul 133-791, South Korea.

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July 2005

Brain SPECT with short focal-length cone-beam collimation.

Med Phys 2005 Jul;32(7Part1):2236-2244

Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115.

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July 2005

The E-cadherin -347G->GA promoter polymorphism and its effect on transcriptional regulation.

Carcinogenesis 2004 Jun 16;25(6):895-9. Epub 2004 Jan 16.

Korean Hereditary Tumor Registry, Cancer Research Center and Cancer Research Institute, Seoul National University, South Korea.

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June 2004

Development of artificial chimerical gene regulatory elements specific for cancer gene therapy.

Oncol Rep 2003 Nov-Dec;10(6):2063-9

Department of Life Science and Research Institute of Natural Sciences, College of Natural Sciences, Hanyang University, Seoul 133-791, Korea.

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June 2004