Mette Nyegaard

Mette Nyegaard

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Mette Nyegaard

Publications by authors named "Mette Nyegaard"

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The International Calmodulinopathy Registry: recording the diverse phenotypic spectrum of un-CALM hearts.

Eur Heart J 2019 Sep;40(35):2976-2978

Department of Chemistry and Bioscience, Aalborg University, Aalborg, Denmark.

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http://dx.doi.org/10.1093/eurheartj/ehz463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748712PMC
September 2019

The ABO locus is associated with increased platelet aggregation in patients with stable coronary artery disease.

Int J Cardiol 2019 07 11;286:152-158. Epub 2019 Feb 11.

Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Health, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1016/j.ijcard.2019.01.090DOI Listing
July 2019

Identification of common genetic risk variants for autism spectrum disorder.

Nat Genet 2019 03 25;51(3):431-444. Epub 2019 Feb 25.

The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.

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http://dx.doi.org/10.1038/s41588-019-0344-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454898PMC
March 2019

Global transcriptional changes in response to cGAMP depend on STING in human THP-1 cells.

Cell Mol Immunol 2018 11 16;15(11):983-985. Epub 2018 May 16.

Department of Biomedicine, Aarhus Research Center for Innate Immunology, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1038/s41423-018-0035-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207737PMC
November 2018

Human Calmodulin Mutations.

Front Mol Neurosci 2018 13;11:396. Epub 2018 Nov 13.

Section for Biotechnology, Department of Chemistry and Bioscience, Aalborg University, Aalborg, Denmark.

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http://dx.doi.org/10.3389/fnmol.2018.00396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243062PMC
November 2018

Biological age of the endometrium using DNA methylation.

Reproduction 2018 02 21;155(2):167-172. Epub 2017 Nov 21.

Department of BiomedicineAarhus University, Aarhus C, Denmark.

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http://dx.doi.org/10.1530/REP-17-0601DOI Listing
February 2018

Evaluating the Feasibility of DNA Methylation Analyses Using Long-Term Archived Brain Formalin-Fixed Paraffin-Embedded Samples.

Mol Neurobiol 2018 01 19;55(1):668-681. Epub 2016 Dec 19.

Department of Biomedicine, Aarhus University, Bartholin building, DK-8000, Aarhus C, Denmark.

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http://dx.doi.org/10.1007/s12035-016-0345-xDOI Listing
January 2018

Epigenome-Wide Association Study of Cognitive Functioning in Middle-Aged Monozygotic Twins.

Front Aging Neurosci 2017 12;9:413. Epub 2017 Dec 12.

The Danish Twin Registry, Institute of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.3389/fnagi.2017.00413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733014PMC
December 2017

The SH2B3 and KCNK5 loci may be implicated in regulation of platelet count, volume, and maturity.

Thromb Res 2017 Oct 18;158:86-92. Epub 2017 Aug 18.

Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Faculty of Health, Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1016/j.thromres.2017.08.009DOI Listing
October 2017

A genetic risk score predicts cardiovascular events in patients with stable coronary artery disease.

Int J Cardiol 2017 Aug 19;241:411-416. Epub 2017 Apr 19.

Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Faculty of Health, Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1016/j.ijcard.2017.04.045DOI Listing
August 2017

Mice heterozygous for an inactivated allele of the schizophrenia associated Brd1 gene display selective cognitive deficits with translational relevance to schizophrenia.

Neurobiol Learn Mem 2017 May 21;141:44-52. Epub 2017 Mar 21.

Department of Biomedicine, Aarhus University, Denmark; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark; Centre for Integrative Sequencing, iSEQ, Aarhus University, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.nlm.2017.03.009DOI Listing
May 2017

A 45-SNP genetic risk score is increased in early-onset coronary artery disease but independent of familial disease clustering.

Atherosclerosis 2017 02 13;257:172-178. Epub 2017 Jan 13.

Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Faculty of Health, Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.01.010DOI Listing
February 2017

Molecular classification of tissue from a transformed non-Hogkin's lymphoma case with unexpected long-time remission.

Exp Hematol Oncol 2017 11;6. Epub 2017 Jan 11.

Department of Hematology, Aalborg University Hospital, Aalborg, Denmark ; Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark ; Department of Clinical Medicine, Aalborg University, Sdr. Skovvej 15, 9000 Aalborg, Denmark.

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http://dx.doi.org/10.1186/s40164-016-0063-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225590PMC
January 2017

Hypomethylation of FAM63B in bipolar disorder patients.

Clin Epigenetics 2016 11;8:52. Epub 2016 May 11.

Department of Biomedicine, Aarhus University, Wilhelm Meyers Alle 4, DK- 8000 Aarhus C, Denmark ; The Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark ; Center for Integrative Sequencing, iSEQ, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1186/s13148-016-0221-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865008PMC
December 2016

Genome-wide DNA methylation profiling with MeDIP-seq using archived dried blood spots.

Clin Epigenetics 2016 26;8:81. Epub 2016 Jul 26.

Translational Neuropsychiatric Unit, Aarhus University Hospital, Risskov, 8240 Denmark ; Research Department P, Aarhus University Hospital, Risskov, 8240 Denmark ; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus C, Denmark.

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http://dx.doi.org/10.1186/s13148-016-0242-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960904PMC
December 2016

Characterization of memory B cells from thymus and its impact for DLBCL classification.

Exp Hematol 2016 10 11;44(10):982-990.e11. Epub 2016 Jun 11.

Department of Haematology, Aalborg University Hospital, Aalborg, Denmark; Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2016.06.001DOI Listing
October 2016

Paternal Hemizygosity in 11p15 in Mole-like Conceptuses: Two Case Reports.

Medicine (Baltimore) 2015 Nov;94(44):e1776

From the Department of Clinical Genetics, Aarhus University Hospital, Aarhus N, Denmark (LS); Institute of Pathology, Aalborg University Hospital, Aalborg, Denmark (HL, AG); Trophoblastic Tumour Screening and Treatment Centre, Department of Oncology, Imperial College Healthcare NHS (NJS, RF); Institute of Child Health, University College London (NJS); Institute of Reproductive and Developmental Biology, Department of Surgery and Cancer, Imperial College London, London, UK (RF); Department of Gynaecology and Obstetrics, Aarhus University Hospital, Aarhus N (IN); Hemodiagnostic Laboratory, CancercytogeneticSection, Aarhus University Hospital, Aarhus C, Denmark (EK); Department of Immunology and Biochemistry, Vejle Sygehus, Vejle, Denmark (LA); Department of Pathology, Aarhus University Hospital, Aarhus C, Denmark (EH); Department of Clinical Genetics, Vejle Sygehus, Vejle, Denmark (AB); Department of Biomedicine, Aarhus University, Aarhus C, Denmark (LS, LB, MN); and Beijing Genomics Institute/HuaDa-Shenzhen, Shenzhen, China (LB).

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http://dx.doi.org/10.1097/MD.0000000000001776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915877PMC
November 2015

Investigating interactions between early life stress and two single nucleotide polymorphisms in HSD11B2 on the risk of schizophrenia.

Psychoneuroendocrinology 2015 Oct 11;60:18-27. Epub 2015 Jun 11.

National Center for Register-based Research, Department of Economics and Business, Aarhus University, Denmark; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark.

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http://dx.doi.org/10.1016/j.psyneuen.2015.05.013DOI Listing
October 2015

The importance of distinguishing between the odds ratio and the incidence rate ratio in GWAS.

BMC Med Genet 2015 Aug 30;16:71. Epub 2015 Aug 30.

Bioinformatics Research Center, Aarhus University, C.F. Møllers Allé 8, 8000, Aarhus C, Denmark.

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http://dx.doi.org/10.1186/s12881-015-0210-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593225PMC
August 2015

Experimental validation of methods for differential gene expression analysis and sample pooling in RNA-seq.

BMC Genomics 2015 Jul 25;16:548. Epub 2015 Jul 25.

Department of Biomedicine, Aarhus University, 6, Bartholins Allé, Aarhus C, Aarhus, 8000, Denmark.

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http://dx.doi.org/10.1186/s12864-015-1767-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515013PMC
July 2015

Diffuse large B-cell lymphoma classification system that associates normal B-cell subset phenotypes with prognosis.

J Clin Oncol 2015 Apr 23;33(12):1379-88. Epub 2015 Mar 23.

Karen Dybkær, Martin Bøgsted, Steffen Falgreen, Julie S. Bødker, Malene K. Kjeldsen, Alexander Schmitz, Anders E. Bilgrau, Kim S. Bergkvist, Maria B. Laursen, Maria Rodrigo-Domingo, Sara C. Marques, Sophie B. Rasmussen, Mette Nyegaard, Michael Gaihede, Preben Johansen, Tarec C. El-Galaly, and Hans E. Johnsen, Aalborg University Hospital; Karen Dybkær, Martin Bøgsted, Anders E. Bilgrau, Maria Rodrigo-Domingo, Michael Gaihede, and Hans E. Johnsen, Aalborg University, Aalborg; Michael B. Møller, Odense University Hospital, Odense, Denmark; Zijun Y. Xu-Monette, Ling Li, and Ken H. Young, The University of Texas MD Anderson Cancer Center, Houston, TX; and Richard J. Samworth and Rajen D. Shah, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2014.57.7080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397280PMC
April 2015

The hypercholesterolemia-risk gene SORT1 facilitates PCSK9 secretion.

Cell Metab 2014 Feb;19(2):310-8

The Lundbeck Foundation Research Center, MIND, Department of Biomedicine, Aarhus University, Vennelyst Boulevard 4, DK-8000 C Aarhus, Denmark; Danish Research Institute of Translational Neuroscience DANDRITE, Nordic EMBL Partnership, Department of Biomedicine, Aarhus University, Vennelyst Boulevard 4, DK-8000 C Aarhus, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2013.12.006DOI Listing
February 2014

Treatment of Aggressive NK-Cell Leukemia: A Case Report and Review of the Literature.

Case Rep Hematol 2011 21;2011:818469. Epub 2011 Nov 21.

Department of Hematology, Aalborg Hospital, Aarhus University Hospital, Hobrovej 18-22, P.O. Box 365, 9100 Aalborg, Denmark.

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http://dx.doi.org/10.1155/2011/818469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420499PMC
August 2012

No association of polymorphisms in human endogenous retrovirus K18 and CD48 with schizophrenia.

Psychiatr Genet 2012 Jun;22(3):146-8

Department of Haematology, Aalborg Hospital Science and Innovation Center, Aarhus University Hospital, Aalborg, Denmark.

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http://dx.doi.org/10.1097/YPG.0b013e328353953cDOI Listing
June 2012

A major imprinted gene involved in hydatidiform mole is not located in 2q31.2-qter or 5q34-qter.

Gene 2012 Apr 9;497(2):280-4. Epub 2012 Feb 9.

Aarhus University Hospital, Aalborg, Denmark.

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http://dx.doi.org/10.1016/j.gene.2012.01.093DOI Listing
April 2012

CtIP Mutations Cause Seckel and Jawad Syndromes.

PLoS Genet 2011 Oct 6;7(10):e1002310. Epub 2011 Oct 6.

Department of Human Genetics and Department of Biomedicine, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1371/journal.pgen.1002310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188555PMC
October 2011

[The haematological biobank--an infrastructure for quality assurance, development and research].

Ugeskr Laeger 2011 May;173(21):1489-93

Hæmatologisk Afdeling, Medicinsk Center, Aarhus Universitetshospital, Aalborg Sygehus, Denmark.

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May 2011

SorLA regulates the activity of lipoprotein lipase by intracellular trafficking.

J Cell Sci 2011 Apr 8;124(Pt 7):1095-105. Epub 2011 Mar 8.

The MIND-Center, Department of Medical Biochemistry, University of Aarhus, Ole Worms Allé 1170, DK 8000 Aarhus C, Denmark.

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http://dx.doi.org/10.1242/jcs.072538DOI Listing
April 2011

[Cancer stem cells in the haematopoietic system].

Ugeskr Laeger 2010 Sep;172(38):2597-600

Århus Universitetshospital, Aalborg Sygehus, Haematologisk Afdeling, Denmark.

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September 2010

Transgenic overexpression of pregnancy-associated plasma protein-A in murine arterial smooth muscle accelerates atherosclerotic lesion development.

Am J Physiol Heart Circ Physiol 2010 Aug 14;299(2):H284-91. Epub 2010 May 14.

Division of Endocrinology, Metabolism and Nutrition, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1152/ajpheart.00904.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930380PMC
August 2010

[Use of translational database at clinical department].

Ugeskr Laeger 2010 Jul;172(28):2062-4

Arhus Universitetshospital, Aalborg Sygehus, Haematologisk Afdeling, Medicinsk Center.

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July 2010

Linkage of atopic dermatitis to chromosomes 4q22, 3p24 and 3q21.

Hum Genet 2009 Oct 11;126(4):549-57. Epub 2009 Jun 11.

Institute of Human Genetics, University of Aarhus, The Bartholin Building, Wilhelm Meyers Allé, 8000 Arhus C, Denmark.

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http://dx.doi.org/10.1007/s00439-009-0692-zDOI Listing
October 2009

Cancer stem cells and the cellular hierarchy in haematological malignancies.

Eur J Cancer 2009 Sep;45 Suppl 1:194-201

Department of Haematology, Medical Centre Aalborg Hospital and Aalborg Hospital Science and Innovation Centre (AHSIC), Aarhus University Hospital, Aalborg, Denmark.

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http://dx.doi.org/10.1016/S0959-8049(09)70033-4DOI Listing
September 2009

Common variants conferring risk of schizophrenia.

Nature 2009 Aug 1;460(7256):744-7. Epub 2009 Jul 1.

deCODE genetics, Sturlugata 8, IS-101 Reykjavik, Iceland.

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http://dx.doi.org/10.1038/nature08186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077530PMC
August 2009

Arrayed primer extension in the "array of arrays" format: a rational approach for microarray-based SNP genotyping.

Genet Test 2007 ;11(2):160-6

Department of Biochemistry, Pharmacology and Genetics, Human MicrroArray Centre, Odense University Hospital, Odense, DK-5000 Odense C, Denmark.

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http://www.liebertpub.com/doi/10.1089/gte.2007.9998
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http://dx.doi.org/10.1089/gte.2007.9998DOI Listing
September 2007

Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis.

Endocrinology 2007 Aug 17;148(8):3814-26. Epub 2007 May 17.

Department of Obstetrics and Gynecology, Stanford University, Stanford, California 94305, USA.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2006-1692DOI Listing
August 2007

Identification of the Slynar gene (AY070435) and related brain expressed sequences as a candidate gene for susceptibility to affective disorders through allelic and haplotypic association with bipolar disorder on chromosome 12q24.

Am J Psychiatry 2006 Oct;163(10):1767-76

Molecular Psychiatry Laboratory, Windeyer Institute for Medical Science, Department of Psychiatry and Behavioral Sciences, Royal Free and University College Medical School, University College London, 46 Cleveland St., London W1T 4JF, United Kingdom.

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http://dx.doi.org/10.1176/ajp.2006.163.10.1767DOI Listing
October 2006

Analysis of transmission of novel polymorphisms in the somatostatin receptor 5 (SSTR5) gene in patients with autism.

Am J Med Genet B Neuropsychiatr Genet 2003 Aug;121B(1):100-4

Department of Psychiatric Demography, Institute for Basic Psychiatric Research, Psychiatric Hospital in Aarhus, Risskov, Denmark.

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http://dx.doi.org/10.1002/ajmg.b.20050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830897PMC
August 2003