Publications by authors named "Merle Ruberg"

61Publications

Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins.

Mol Neurodegener 2016 07 28;11(1):58. Epub 2016 Jul 28.

INSERM U 1127, CNRS UMR 7225, Sorbonne Universités UPMC, Univ Paris 06 UMR_S 1127, ICM (Brain and Spine Institute) Pitié-Salpêtrière Hospital, 75013, Paris, France.

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http://dx.doi.org/10.1186/s13024-016-0123-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964261PMC
July 2016

The impact of familial structure on Parkinson's disease in Istanbul Medical School, Turkey.

Int J Neurosci 2012 Feb 1;122(2):102-5. Epub 2011 Dec 1.

Department of Neurology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey.

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http://dx.doi.org/10.3109/00207454.2011.631715DOI Listing
February 2012

Atypical parkinsonism in the Caribbean island of Guadeloupe: etiological role of the mitochondrial complex I inhibitor annonacin.

Mov Disord 2008 Nov;23(15):2122-8

INSERM, UMR_S 679, Hôpital de la Salpêtrière,, Paris, France.

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http://doi.wiley.com/10.1002/mds.22300
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http://dx.doi.org/10.1002/mds.22300DOI Listing
November 2008

The PSP-associated MAPT H1 subhaplotype in Guadeloupean atypical parkinsonism.

Mov Disord 2008 Dec;23(16):2384-91

INSERM, UMR_S 679, Neurology and Experimental Therapeutics, Paris, France.

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http://dx.doi.org/10.1002/mds.22297DOI Listing
December 2008

Recent advances in the genetics of spastic paraplegias.

Curr Neurol Neurosci Rep 2008 May;8(3):198-210

INSERM / UPMC Univ Paris-6 UMR_S679, Groupe Hospitalier Pitié-Salpêtrière, 47 Bd de l'Hôpital, 75013 Paris, France.

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http://dx.doi.org/10.1007/s11910-008-0032-zDOI Listing
May 2008

Frequency of the LRRK2 G2019S mutation in siblings with Parkinson's disease.

Neurodegener Dis 2007 ;4(2-3):195-8

INSERM, UMR 679, Neurology and Experimental Therapeutics, Hôpital de la Pitié-Salpêtrière, AP-HP, Faculté de Médecine, Université Pierre et Marie Curie-Paris 6, Paris, France.

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http://dx.doi.org/10.1159/000101844DOI Listing
October 2007

Stimulation of subterritories of the subthalamic nucleus reveals its role in the integration of the emotional and motor aspects of behavior.

Proc Natl Acad Sci U S A 2007 Jun 7;104(25):10661-6. Epub 2007 Jun 7.

Institut National de la Santé et de la Recherche Médicale AVENIR Group, Behavior, Emotion, and Basal Ganglia, 75013 Paris, France.

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http://dx.doi.org/10.1073/pnas.0610849104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1965569PMC
June 2007

Silencing of the Charcot-Marie-Tooth associated MTMR2 gene decreases proliferation and enhances cell death in primary cultures of Schwann cells.

Neurobiol Dis 2007 May 25;26(2):323-31. Epub 2007 Jan 25.

UMR 679 INSERM (formely U289)-Université Pierre et Marie Curie, IFR70, Faculté de Médecine Pierre et Marie Curie, Paris, France.

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http://dx.doi.org/10.1016/j.nbd.2006.12.018DOI Listing
May 2007

Metabolic activity of cerebellar and basal ganglia-thalamic neurons is reduced in parkinsonism.

Brain 2007 Jan;130(Pt 1):265-75

INSERM, UMR679, Neurology and Experimental Therapeutics, Paris, France.

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http://dx.doi.org/10.1093/brain/awl337DOI Listing
January 2007

PML clastosomes prevent nuclear accumulation of mutant ataxin-7 and other polyglutamine proteins.

J Cell Biol 2006 Jul;174(1):65-76

Institut National de la Santé et de la Recherche Médicale U679, Neurologie et Thérapeutique Expérimentale, 75651 Paris Cedex 13, France.

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http://dx.doi.org/10.1083/jcb.200511045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064165PMC
July 2006

Dopaminergic neurons reduced to silence by oxidative stress: an early step in the death cascade in Parkinson's disease?

Sci STKE 2006 Apr 25;2006(332):pe19. Epub 2006 Apr 25.

INSERM U679, Experimental Neurology and Therapeutics, 75013 Paris, France.

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http://dx.doi.org/10.1126/stke.3322006pe19DOI Listing
April 2006

Polyglutamine and polyalanine expansions in ataxin7 result in different types of aggregation and levels of toxicity.

Mol Cell Neurosci 2006 Mar 1;31(3):438-45. Epub 2005 Dec 1.

INSERM U679 (former U289), Neurologie et Thérapeutique Expérimentale, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.

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http://dx.doi.org/10.1016/j.mcn.2005.10.013DOI Listing
March 2006

Quantification of acetogenins in Annona muricata linked to atypical parkinsonism in guadeloupe.

Mov Disord 2005 Dec;20(12):1629-33

Laboratory of Pharmacognosy, UMR 8076 Centre National de la Recherche Scientifique BioCIS, Faculté de Pharmacie Paris XI, Châtenay-Malabry, France.

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http://dx.doi.org/10.1002/mds.20632DOI Listing
December 2005

Detection of genomic rearrangements by DHPLC: a prospective study of 90 patients with inherited peripheral neuropathies associated with 17p11.2 rearrangements.

Am J Med Genet A 2005 Jul;136(2):136-9

Département de Génétique, Cytogénétique et Embryologie, Hôpital Pitié-Salpétriére, AP-HP, Paris, France.

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http://dx.doi.org/10.1002/ajmg.a.30790DOI Listing
July 2005

Neurotoxic calcium transfer from endoplasmic reticulum to mitochondria is regulated by cyclin-dependent kinase 5-dependent phosphorylation of tau.

J Neurosci 2005 Apr;25(16):4159-68

Institut National de la Santé et de la Recherche Médicale U679, Neurologie et Thérapeutique Expérimentale, Hôpital de la Salpêtrière, 75013 Paris, France.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.0060-05.2
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http://dx.doi.org/10.1523/JNEUROSCI.0060-05.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724963PMC
April 2005

Mapping of a new form of pure autosomal recessive spastic paraplegia (SPG28).

Ann Neurol 2005 Apr;57(4):567-71

INSERM U679 (former U289), Federative Institute for Neuroscience Research (IFR70), Salpetriere Hospital, Paris, France.

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http://dx.doi.org/10.1002/ana.20416DOI Listing
April 2005

Parkinson's disease: from causes to mechanisms.

C R Biol 2005 Feb;328(2):131-42

INSERM U 289, hôpital de la Pitié-Salpêtrière, 47, bd de l'Hôpital, 75013 Paris, France.

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http://dx.doi.org/10.1016/j.crvi.2004.10.009DOI Listing
February 2005

Atlastin1 mutations are frequent in young-onset autosomal dominant spastic paraplegia.

Arch Neurol 2004 Dec;61(12):1867-72

Département de Génétique, Cytogénétique et Embryologie, and INSERM U289, Hôpital Salpêtrière AP-HP, Paris, France.

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http://dx.doi.org/10.1001/archneur.61.12.1867DOI Listing
December 2004

Mutation in the catalytic domain of protein kinase C gamma and extension of the phenotype associated with spinocerebellar ataxia type 14.

Arch Neurol 2004 Aug;61(8):1242-8

INSERM U289, Institut Fédératif de Recherche en Neuroscience, Assistance Publique Hôpitaux de Paris, Hôpital de al Salpêtrière, Paris, France.

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http://dx.doi.org/10.1001/archneur.61.8.1242DOI Listing
August 2004

Rescue of mesencephalic dopaminergic neurons in culture by low-level stimulation of voltage-gated sodium channels.

J Neurosci 2004 Jun;24(26):5922-30

Institut National de la Santé et de la Recherche Médicale U289, Experimental Neurology and Therapeutics, Hôspital de la Salpêtrière, 75013 Paris, France.

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http://dx.doi.org/10.1523/JNEUROSCI.5668-03.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6729237PMC
June 2004

Monogenic idiopathic epilepsies.

Lancet Neurol 2004 Apr;3(4):209-18

Unité d'Epileptologie, Assistace Publique Hôpitaux, and INSERM U 289, Hôpital de la Pitié-Salpêtrière, Paris, France.

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http://dx.doi.org/10.1016/S1474-4422(04)00706-9DOI Listing
April 2004

Subtle cognitive impairment but no dementia in patients with spastin mutations.

Arch Neurol 2003 Aug;60(8):1113-8

Institut National de la Santé et de la Recherche Médicale Unit 289, Fédération de Neurologie, Hôpital de la Salpêtrière, 47 boulevard de l'Hôpital, 75013 Paris, France.

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http://dx.doi.org/10.1001/archneur.60.8.1113DOI Listing
August 2003

Prevention of dopaminergic neuronal death by cyclic AMP in mixed neuronal/glial mesencephalic cultures requires the repression of presumptive astrocytes.

Mol Pharmacol 2003 Sep;64(3):578-86

INSERM 289, Experimental Neurology and Therapeutics, Bâtiment Pharmacie, Hôpital de la Salpêtrière, 47 bd de l'Hôpital, 75013 Paris, France.

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http://dx.doi.org/10.1124/mol.64.3.578DOI Listing
September 2003

Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease.

J Neurochem 2003 Sep;86(5):1297-307

INSERM U289, Experimental Neurology and Therapeutics, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital, 75651 Paris Cedex 13, France.

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http://dx.doi.org/10.1046/j.1471-4159.2003.01952.xDOI Listing
September 2003

Activation of mitogen-activated protein kinase pathways during the death of PC12 cells is dependent on the state of differentiation.

Brain Res Mol Brain Res 2003 Mar;111(1-2):52-60

INSERM U.289, Hôpital de la Salpêtrière, 47 boulevard de l'Hôpital, 75013 Paris, France.

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http://dx.doi.org/10.1016/s0169-328x(02)00669-1DOI Listing
March 2003

Ceramide increases mitochondrial free calcium levels via caspase 8 and Bid: role in initiation of cell death.

J Neurochem 2003 Feb;84(4):643-54

INSERM U289, Hôpital de la Salpêtrière, 47 boulevard de l'Hôpital, 75013 Paris, France.

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http://dx.doi.org/10.1046/j.1471-4159.2003.01590.xDOI Listing
February 2003

Chronic systemic complex I inhibition induces a hypokinetic multisystem degeneration in rats.

J Neurochem 2003 Feb;84(3):491-502

INSERM U 289, Experimental Neurology and Therapeutics, Hôpital de la Salpêtrière, Paris, France.

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http://dx.doi.org/10.1046/j.1471-4159.2003.01533.xDOI Listing
February 2003

Activation of the mitogen-activated protein kinase (ERK(1/2)) signaling pathway by cyclic AMP potentiates the neuroprotective effect of the neurotransmitter noradrenaline on dopaminergic neurons.

Mol Pharmacol 2002 Nov;62(5):1043-52

Institut National de la Santé et de la Recherche Médicale U289, Experimental Neurology and Therapeutics, Hôpital de la Salpêtrière, Paris, France.

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http://dx.doi.org/10.1124/mol.62.5.1043DOI Listing
November 2002

Toxicity of Annonaceae for dopaminergic neurons: potential role in atypical parkinsonism in Guadeloupe.

Mov Disord 2002 Jan;17(1):84-90

Service de Neurologie, Centre hospitalier universitaire des Antilles et de la Guyane, Pointe-à-Pitre, Guadeloupe, France.

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http://dx.doi.org/10.1002/mds.1246DOI Listing
January 2002