Publications by authors named "Merit Cudkowicz"

99Publications

Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis.

N Engl J Med 2020 09;383(10):919-930

From the Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School (S.P., J.D.B., S.B., M.C., D.D., M.M., J.O., L.P., A.V.S., E.T., P.V., J. Walker, H.Y., R.E.T., M.E.C.), the Biostatistics Center, Massachusetts General Hospital, Harvard Medical School (E.A.M., J. Chan, D.S.), and Spaulding Rehabilitation Hospital, Harvard Medical School (S.P.), Boston, the University of Massachusetts Memorial Medical Center, Worcester (M.A.O.), and Amylyx Pharmaceuticals (J. Cohen, J. Klee, K.L., P.D.Y.) and Harvard University (W.G.), Cambridge - all in Massachusetts; Pentara, Millcreek, UT (S.H., S.P.D., N.E., K.H.); Swedish Neuroscience Institute, Seattle (M.A.E.); Hennepin Healthcare, Minneapolis (S.M.); the Department of Neurology, Oregon Health and Science University, Portland (C.K.); the Department of Neurology, Wake Forest School of Medicine, Winston-Salem, NC (J.B.C.); the Department of Neurology, Ohio State University College of Medicine, Columbus (A.Q.); the Department of Neurology, University of Florida College of Medicine, Gainesville (J. Wymer); the Department of Neurology, University of Michigan, Ann Arbor (S.A.G.); Texas Neurology, Dallas (D.H.); the Department of Neurology, Lewis Katz School of Medicine, Temple University (T.H.-P.), and the Department of Neurology, University of Pennsylvania Perelman School of Medicine (C.Q.) - both in Philadelphia; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Disease, University of Texas Health Science Center at San Antonio, San Antonio (C.E.J.); the Brain Science Institute and Department of Neurology, Johns Hopkins University, Baltimore (J.D.R.); the Department of Neurology, University of Kentucky College of Medicine, Lexington (E.J.K.); California Pacific Medical Center and Forbes Norris MDA-ALS Research and Treatment Center, San Francisco (J. Katz, L.J.); Barrow Neurological Institute, Phoenix, AZ (S.L., M.H., G.K., R.R., J.M.S.); the Department of Neurology, Washington University School of Medicine in St. Louis, St. Louis (T.M.M.); the Department of Neurology, Mount Sinai Beth Israel, Icahn School of Medicine at Mount Sinai, New York (S.N.S.); the Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (T.H.V.); the Departments of Neurology and Pathology, Emory University School of Medicine, Atlanta (C.N.F., J.D.G.); Ochsner Health System, New Orleans (K.M.J.); the Department of Neurology, University of Iowa Carver College of Medicine, Iowa City (A.S.); the Department of Neurology, University of California, Irvine, School of Medicine, Irvine (N.A.G.); Neurology Associates, Lincoln, NB (G.L.P.); independent consultant, Nobleboro, ME (P.L.A.); and Statistics Collaborative, Washington, DC (J. Wittes).

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http://dx.doi.org/10.1056/NEJMoa1916945DOI Listing
September 2020

Suppression with Adeno-Associated Virus and MicroRNA in Familial ALS.

N Engl J Med 2020 07;383(2):151-158

From the Horae Gene Therapy Center, Department of Pediatrics, University of Massachusetts Medical School (UMMS) (C.M., G.G., M.B., T.R.F.), and the Department of Neurology, UMMS and UMass Memorial Medical Center (D.M.M.-Y., M.A.O., C.L.D., N.S.W., R.H.B.), Worcester, and the Healey Center for ALS, Department of Neurology (J.D.B., L.M.P., D.G., S.D.L., M.P.F., M.E.C.), and the C.S. Kubik Laboratory for Neuropathology (D.H.O., M.P.F.), Massachusetts General Hospital and Harvard Medical School, Boston.

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http://dx.doi.org/10.1056/NEJMoa2005056DOI Listing
July 2020

Phase 1-2 Trial of Antisense Oligonucleotide Tofersen for ALS.

N Engl J Med 2020 07;383(2):109-119

From the Washington University School of Medicine, St. Louis (T.M., R.C.B., A.P.); the Healey Center for ALS, Massachusetts General Hospital, Harvard Medical School, Boston (M.C., N.A.), and Biogen, Cambridge (A.S., H.R., D.G., H.H., A.M., I.N., I.C., L.F., S.F., T.A.F.) - both in Massachusetts; the Sheffield Institute for Translational Neuroscience, University of Sheffield, and NIHR Sheffield Biomedical Research Centre and Clinical Research Facility, University of Sheffield and Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield (P.J.S., C.J.M.), and Biogen, Maidenhead (M.M.) - both in the United Kingdom; the Department of Clinical Science, Neurosciences, Umeå University, Umea, Sweden (P.M.A.); Montreal Neurological Institute and Hospital, Montreal (A.G.), and Sunnybrook Research Institute, Toronto (L.Z.); Emory University, Atlanta (J.G.); Barrow Neurological Institute, Phoenix, AZ (S.L.); the University of Ulm, Ulm, Germany (A.L.L.); Johns Hopkins University School of Medicine, Baltimore (N.J.M.); the University of California San Diego, La Jolla (J.R.), and Ionis Pharmaceuticals, Carlsbad (C.F.B., R.L.) - both in California; Paris ALS Centre, Hôpital de la Salpêtrière, Paris (F.S.); the University of Tennessee Medical Center, Knoxville (R.T.); and KU Leuven, VIB Center for Brain and Disease Research, University Hospitals Leuven, Leuven, Belgium (P.V.D.).

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http://dx.doi.org/10.1056/NEJMoa2003715DOI Listing
July 2020

ALS clinical research learning institutes (ALS-CRLI): empowering people with ALS to be research ambassadors.

Amyotroph Lateral Scler Frontotemporal Degener 2020 05 15;21(3-4):216-221. Epub 2019 Nov 15.

MDA/ALS Center of Hope, Temple Health, Philadelphia, PA, USA.

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http://dx.doi.org/10.1080/21678421.2019.1690519DOI Listing
May 2020

Seven-Year Experience From the National Institute of Neurological Disorders and Stroke-Supported Network for Excellence in Neuroscience Clinical Trials.

JAMA Neurol 2020 Jun;77(6):755-763

University of Rochester, Rochester, New York.

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http://dx.doi.org/10.1001/jamaneurol.2020.0367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483960PMC
June 2020

NurOwn, phase 2, randomized, clinical trial in patients with ALS: Safety, clinical, and biomarker results.

Neurology 2019 12 18;93(24):e2294-e2305. Epub 2019 Nov 18.

From Massachusetts General Hospital Neurological Clinical Research Institute and Harvard Medical School (J.D.B., M.E.C., K.N.), Boston; Mayo Clinic (A.J.W., N.P.S.), Rochester, MN; University of Massachusetts (M.O., D.M.-Y., R.H.B.), Worcester; Brainstorm Cell Therapeutics (Y.S.L., N.A., H.K., R.A., Y.G.), Petach Tikva, Israel; and Tigermed USA (M.M.), Somerset, NJ.

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http://dx.doi.org/10.1212/WNL.0000000000008620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937497PMC
December 2019

IL6 receptorAla variant and trans-signaling are disease modifiers in amyotrophic lateral sclerosis.

Neurol Neuroimmunol Neuroinflamm 2019 11 14;6(6):e631. Epub 2019 Oct 14.

From the Department of Neurobiology and Anatomy (M.W.-K., M.R., J.S., P.A., M.M., C.M.); Department of Neurology (J.C., M. Cartwright); and Department of Biochemistry (G.A.H.), Wake Forest School of Medicine; Division of Public Health (C.L.), Department of Biostatistical Sciences, Wake Forest School of Medicine; Departments of Neurology and Neurobiology (R.B.), Barrow Neurological Institute & St. Joseph's Hospital and Medical Center; Department of Neurology (M. Cudkowicz), Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School; and Current Address Department of Pediatrics (M.M.), Nationwide Children's Hospital, Columbus OH.

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http://dx.doi.org/10.1212/NXI.0000000000000631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865852PMC
November 2019

Selection design phase II trial of high dosages of tamoxifen and creatine in amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2020 02 14;21(1-2):15-23. Epub 2019 Oct 14.

Department of Neurology, Sean M Healey & AMG Center for ALS at Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, MA, USA.

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http://dx.doi.org/10.1080/21678421.2019.1672750DOI Listing
February 2020

Prospective natural history study of ALS clinical characteristics and biomarkers.

Neurology 2019 10 2;93(17):e1605-e1617. Epub 2019 Oct 2.

From the Department of Neurology (A.J.C., T.H., C.D., J.J.-B., A.M., S.B., A.S., T.J.E., C.C., T.M.M.), Washington University School of Medicine, St. Louis, MO; Department of Neurology (N.A., H.Y., A.V.S., M.C.), Neurological Clinical Research Institute, Massachusetts General Hospital, Boston; Department of Neurology (L.H.v.d.B., M.A.v.E., J.H.V., B.S.d.V.), Brain Center Rudolf Magnus, University Medical Center Utrecht, University Utrecht, the Netherlands; Department of Neurology (M.H.), Columbia University, New York, NY; Department of Neurology (R.H. Baloh), Cedars-Sinai Medical Center, Los Angeles, CA; Department of Neurology (R.H. Brown, N.W., D.M.-Y., M.A.O., C.D.), University of Massachusetts, Worcester; Department of Neurology (J.D.R.), Johns Hopkins University, Baltimore, MD; and Biogen Inc. (A.M., T.F.), Boston, MA.

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http://dx.doi.org/10.1212/WNL.0000000000008359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946465PMC
October 2019

ALS/SURV: a modification of the CAFS statistic.

Amyotroph Lateral Scler Frontotemporal Degener 2019 11 23;20(7-8):576-583. Epub 2019 Jul 23.

Department of Neurology, University of Michigan , Ann Arbor , MI , USA.

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http://dx.doi.org/10.1080/21678421.2019.1643375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768708PMC
November 2019

Opinion and Special Articles: Challenges and opportunities in defining career identity in academic neurology.

Neurology 2018 10;91(14):670-672

From the Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000006284DOI Listing
October 2018

Phase 2 Trial of Ibudilast in Progressive Multiple Sclerosis.

N Engl J Med 2018 08;379(9):846-855

From the Mellen Center for Multiple Sclerosis, Neurological Institute (R.J.F., S. Natarajan, R.A.B., D.O.), the Imaging Institute (X.H., M.J.L., K.E.S., X.Z.), and the Department of Biomedical Engineering (P.J., K.N., B. Thoomukuntla), Cleveland Clinic, Cleveland, Ohio State University, Columbus (M.R.), and University of Cincinnati, Cincinnati (A.Z.) - all in Ohio; the Data Coordinating Center, Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT), University of Iowa, Iowa City (C.S.C., J.B., D.E., E.K., M.K., J.D.L., J.Y.); the National Institute of Neurological Disorders and Stroke, Bethesda, MD (R.C.); the Clinical Coordinating Center, NeuroNEXT, Massachusetts General Hospital, Neurological Clinical Research Institute, Harvard Partners (M.E.C., M.M., A.A., B. Thornell), the Department of Neurology, Massachusetts General Hospital, Harvard Medical School (E.C.K.), and Brigham and Women's Hospital (C.S.), Boston; patient advocate (T.G.) and Swedish Medical Center at Seattle (P.R.), Seattle; University of Rochester Medical Center, Rochester (A.G.), Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Mount Sinai Medical Center (S.K.), Weill Cornell Medical College (J.S.P.), Columbia University Medical Center (C.S.R.), and Montefiore Medical Center, Albert Einstein College of Medicine (S.S.), New York, State University of New York (SUNY) at Stony Brook, Stony Brook (P.K.C.), SUNY Upstate Medical University, Syracuse (B.J.), and SUNY at Buffalo, Buffalo (B.W.-G.) - all in New York; MediciNova, La Jolla (K.M.), University of California at Davis, Sacramento (M.A.), and University of California at Los Angeles, Los Angeles (B.S.G.) - all in California; Washington University School of Medicine, St. Louis (R.T.N.); Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ (J.P.D.); NeuroRx Research, Montreal (S. Narayanan); the School of Health Sciences, College of Health and Human Sciences, Purdue University, West Lafayette, IN (X.Z.); University of Colorado Denver, Aurora (E.A.); University of Alabama at Birmingham, Birmingham (K.B.); Feinberg School of Medicine, Northwestern University, Chicago (B.A.C.); University of Miami Miller School of Medicine, Miami (S.D.); University of Utah, Salt Lake City (L.D.D.); University of Texas Southwestern Medical Center, Dallas (A.F.); University of Virginia at Charlottesville, Charlottesville (M.D.G.); Emory University, Atlanta (N.L.); University of Kansas Medical Center, Kansas City (S.G.L.); Vanderbilt University, Nashville (H.M.); University of Pittsburgh Medical Center, Pittsburgh (V.S.); and Oregon Health and Science University, Portland (V.Y.).

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http://dx.doi.org/10.1056/NEJMoa1803583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172944PMC
August 2018

Long-term Phase 1/2 intraspinal stem cell transplantation outcomes in ALS.

Ann Clin Transl Neurol 2018 Jun 2;5(6):730-740. Epub 2018 May 2.

Department of Neurology University of Michigan 109 Zina Pitcher Place 5017 AAT-BSRB Ann Arbor Michigan 48109.

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http://doi.wiley.com/10.1002/acn3.567
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http://dx.doi.org/10.1002/acn3.567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989736PMC
June 2018

Expanded autologous regulatory T-lymphocyte infusions in ALS: A phase I, first-in-human study.

Neurol Neuroimmunol Neuroinflamm 2018 Jul 18;5(4):e465. Epub 2018 May 18.

Houston Methodist Neurological Institute (J.R.T., D.R.B., W.Z., M.P., E.P.S., S.H.A.), Houston Methodist Hospital Research Institute, Stanley H. Appel Department of Neurology, Houston, TX; and Neurological Clinical Research Institute (J.D.B., M.E.C.), Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1212/NXI.0000000000000465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961523PMC
July 2018

Understanding the use of NIV in ALS: results of an international ALS specialist survey.

Amyotroph Lateral Scler Frontotemporal Degener 2018 08 16;19(5-6):331-341. Epub 2018 Apr 16.

k Department of Neurology, Brain Centre Rudolf Magnus , University Medical Centre Utrecht , Utrecht , The Netherlands.

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http://dx.doi.org/10.1080/21678421.2018.1457058DOI Listing
August 2018

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

Authors:
Aude Nicolas Kevin P Kenna Alan E Renton Nicola Ticozzi Faraz Faghri Ruth Chia Janice A Dominov Brendan J Kenna Mike A Nalls Pamela Keagle Alberto M Rivera Wouter van Rheenen Natalie A Murphy Joke J F A van Vugt Joshua T Geiger Rick A Van der Spek Hannah A Pliner Shankaracharya Bradley N Smith Giuseppe Marangi Simon D Topp Yevgeniya Abramzon Athina Soragia Gkazi John D Eicher Aoife Kenna Gabriele Mora Andrea Calvo Letizia Mazzini Nilo Riva Jessica Mandrioli Claudia Caponnetto Stefania Battistini Paolo Volanti Vincenzo La Bella Francesca L Conforti Giuseppe Borghero Sonia Messina Isabella L Simone Francesca Trojsi Fabrizio Salvi Francesco O Logullo Sandra D'Alfonso Lucia Corrado Margherita Capasso Luigi Ferrucci Cristiane de Araujo Martins Moreno Sitharthan Kamalakaran David B Goldstein Aaron D Gitler Tim Harris Richard M Myers Hemali Phatnani Rajeeva Lochan Musunuri Uday Shankar Evani Avinash Abhyankar Michael C Zody Julia Kaye Steven Finkbeiner Stacia K Wyman Alex LeNail Leandro Lima Ernest Fraenkel Clive N Svendsen Leslie M Thompson Jennifer E Van Eyk James D Berry Timothy M Miller Stephen J Kolb Merit Cudkowicz Emily Baxi Michael Benatar J Paul Taylor Evadnie Rampersaud Gang Wu Joanne Wuu Giuseppe Lauria Federico Verde Isabella Fogh Cinzia Tiloca Giacomo P Comi Gianni Sorarù Cristina Cereda Philippe Corcia Hannu Laaksovirta Liisa Myllykangas Lilja Jansson Miko Valori John Ealing Hisham Hamdalla Sara Rollinson Stuart Pickering-Brown Richard W Orrell Katie C Sidle Andrea Malaspina John Hardy Andrew B Singleton Janel O Johnson Sampath Arepalli Peter C Sapp Diane McKenna-Yasek Meraida Polak Seneshaw Asress Safa Al-Sarraj Andrew King Claire Troakes Caroline Vance Jacqueline de Belleroche Frank Baas Anneloor L M A Ten Asbroek José Luis Muñoz-Blanco Dena G Hernandez Jinhui Ding J Raphael Gibbs Sonja W Scholz Mary Kay Floeter Roy H Campbell Francesco Landi Robert Bowser Stefan M Pulst John M Ravits Daniel J L MacGowan Janine Kirby Erik P Pioro Roger Pamphlett James Broach Glenn Gerhard Travis L Dunckley Christopher B Brady Neil W Kowall Juan C Troncoso Isabelle Le Ber Kevin Mouzat Serge Lumbroso Terry D Heiman-Patterson Freya Kamel Ludo Van Den Bosch Robert H Baloh Tim M Strom Thomas Meitinger Aleksey Shatunov Kristel R Van Eijk Mamede de Carvalho Maarten Kooyman Bas Middelkoop Matthieu Moisse Russell L McLaughlin Michael A Van Es Markus Weber Kevin B Boylan Marka Van Blitterswijk Rosa Rademakers Karen E Morrison A Nazli Basak Jesús S Mora Vivian E Drory Pamela J Shaw Martin R Turner Kevin Talbot Orla Hardiman Kelly L Williams Jennifer A Fifita Garth A Nicholson Ian P Blair Guy A Rouleau Jesús Esteban-Pérez Alberto García-Redondo Ammar Al-Chalabi Ekaterina Rogaeva Lorne Zinman Lyle W Ostrow Nicholas J Maragakis Jeffrey D Rothstein Zachary Simmons Johnathan Cooper-Knock Alexis Brice Stephen A Goutman Eva L Feldman Summer B Gibson Franco Taroni Antonia Ratti Cinzia Gellera Philip Van Damme Wim Robberecht Pietro Fratta Mario Sabatelli Christian Lunetta Albert C Ludolph Peter M Andersen Jochen H Weishaupt William Camu John Q Trojanowski Vivianna M Van Deerlin Robert H Brown Leonard H van den Berg Jan H Veldink Matthew B Harms Jonathan D Glass David J Stone Pentti Tienari Vincenzo Silani Adriano Chiò Christopher E Shaw Bryan J Traynor John E Landers

Neuron 2018 03;97(6):1268-1283.e6

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867896PMC
March 2018

Respiratory measures in amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2018 08 23;19(5-6):321-330. Epub 2018 Mar 23.

f Eleanor and Lou Gehrig ALS Center, The Neurological Institute, Columbia University , New York , NY , USA.

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http://dx.doi.org/10.1080/21678421.2018.1452945DOI Listing
August 2018

Randomized, double-blind, placebo-controlled trial of arimoclomol in rapidly progressive ALS.

Neurology 2018 02 24;90(7):e565-e574. Epub 2018 Jan 24.

From the Department of Neurology (M.B., J.W.), University of Miami, FL; Department of Pharmacology and Clinical Neuroscience (P.M.A.), Umeå University, Sweden; Department of Neurology (N.A., W.D., M.C.), Massachusetts General Hospital (D.S.), Harvard Medical School; and Department of Biostatistics (D.S.), Harvard Chan School of Public Health, Boston, MA.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000004960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818014PMC
February 2018

Imaging of glia activation in people with primary lateral sclerosis.

Neuroimage Clin 2018 25;17:347-353. Epub 2017 Oct 25.

Harvard Medical School, Department of Neurology, Neurological Clinical Research Institute (NCRI), Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.nicl.2017.10.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681341PMC
June 2018

Motor, cognitive, and functional declines contribute to a single progressive factor in early HD.

Neurology 2017 Dec 15;89(24):2495-2502. Epub 2017 Nov 15.

From F. Hoffman-La Roche, Ltd (S.A.S., G.P., O.S.K., D.T., J.J.S.), Roche Innovation Center, Basel, Switzerland; University of Rochester (P.A., S.M., E.R.D., K.D.K.), NY; University of Iowa (J.D.L., D.R.L.), Iowa City; Massachusetts General Hospital and Harvard Medical School (M.C., S.H.), Boston; CHDI Management/Foundation (C.S.), Princeton, NJ; University of British Columbia, Vancouver, Canada (B.R.L.); and University College London (S.J.T.), UK.

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http://dx.doi.org/10.1212/WNL.0000000000004743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729794PMC
December 2017

Urate levels predict survival in amyotrophic lateral sclerosis: Analysis of the expanded Pooled Resource Open-Access ALS clinical trials database.

Muscle Nerve 2018 03 21;57(3):430-434. Epub 2017 Sep 21.

Department of Neurology, Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, 165 Cambridge St, Suite 600 Boston, Massachusetts, 02114.

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http://dx.doi.org/10.1002/mus.25950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812805PMC
March 2018

Functional Decline is Associated with Hopelessness in Amyotrophic Lateral Sclerosis (ALS).

J Neurol Neurophysiol 2017 Apr 29;8(2). Epub 2017 Apr 29.

Department of Neurology, Neurological Clinical Research Institute (NCRI), Massachusetts General Hospital; Harvard Medical School, USA.

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http://dx.doi.org/10.4172/2155-9562.1000423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548143PMC
April 2017

Analysis of Participant Withdrawal in Huntington Disease Clinical Trials.

J Huntingtons Dis 2017 ;6(2):149-156

Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.3233/JHD-170246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565148PMC
March 2018

Developing multidisciplinary clinics for neuromuscular care and research.

Muscle Nerve 2017 Nov 29;56(5):848-858. Epub 2017 Aug 29.

Harvard Medical School, Department of Neurology, Massachusetts General Hospital (MGH), Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/mus.25725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656914PMC
November 2017

Vitamin D levels are associated with gross motor function in amyotrophic lateral sclerosis.

Muscle Nerve 2017 Oct 5;56(4):726-731. Epub 2017 Apr 5.

Neurological Clinical Research Institute, Harvard Medical School, Massachusetts General Hospital, 165 Cambridge Street, Suite 600, Boston, Massachusetts, 02114, USA.

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http://doi.wiley.com/10.1002/mus.25555
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http://dx.doi.org/10.1002/mus.25555DOI Listing
October 2017

A randomized, double-blind, placebo-controlled trial of coenzyme Q10 in Huntington disease.

Neurology 2017 Jan 2;88(2):152-159. Epub 2016 Dec 2.

From Cooper University Healthcare at Rowan University (A.M.), Camden, NJ; University of Rochester (M.M., K.K., E.A.d.B., K.B., P.C.); Weill Cornell Medical Center (F.B.); Columbia Presbyterian Medical Center (K.M.), New York, NY; Johns Hopkins Medical Center (C.R.), Baltimore, MD; Georgetown University (I.S.), Washington, DC; NINDS (P.G.), Bethesda, MD; Hereditary Neurological Disease Center (W.M.M.), Wichita, KS; The Centre for Movement Disorders (M.G.), Toronto, Canada; Indiana University School of Medicine (J.W.), Indianapolis; Colorado Neurological Institute (R.K.), Englewood; University of Tennessee Health Science Center (M.S.L.), Memphis; London Health Sciences Centre (M.J.), Canada; Massachusetts General Hospital (H.D.R.), Boston; Struthers Parkinson's Center (M.N.), Minneapolis, MN; University of Kansas Medical Center (R.M.D.), Kansas City; Rush University Medical Center (K.M.S.), Chicago, IL; University of Texas Southwestern Medical Center (P.O.), Dallas; University of Michigan (K.C.), Ann Arbor; Wake Forest University (F.W.), Winston-Salem, NC; University of Alberta (W.M.), Edmonton, Canada; University of California Davis (V.L.W.), Sacramento; Westmead Hospital (E. McCusker), Westmead, Australia; Baylor College of Medicine (J.J.), Houston, TX; University of Miami Miller School of Medicine (C.S.), FL; University of South Florida (J.S.-R.), Tampa; Duke University (B.S.), Durham, NC; University of Calgary (O.S.), Canada; Emory University School of Medicine (S.A.F.), Atlanta, GA; Albany Medical College (D.S.H., Eric Molho), NY; University of Cincinnati (F.R.), OH; Mayo Clinic Arizona (J.N.C.), Scottsdale; Butler Hospital (J.H.F.), Providence, RI; Washington University (J.S.P.), St. Louis, MO; Feinstein Institute for Medical Research (A.F.), Manhasset, NY; Georgetown University (K.A.), Washington, DC; University of Florida (R.R., N.R.M.), Gainesville; Johns Hopkins University (R.L.M.), Baltimore, MD; University of Nevada School of Medicine (E.S.F.), Reno; University of British Columbia (L.A.R.), Vancouver, Canada; University of Pittsburgh (V.S.), PA; Ohio State University (S.K.), Columbus; The Cooper University Health System (A.C.), Camden, NJ; Idaho Elks Rehabilitation Hospital (L.S.), Boise, ID; University of Iowa (E.E.), Iowa City; North York General Hospital 1 (S.E.), Toronto, Canada; St. Luke's Hospital (N.D.), Allentown, PA; North York General Hospital 2 (W.L.A.F.), University of Toronto, Canada; Washington Regional Medical Center (A.D.), Fayetteville, AR; Beth-Israel Deaconess Medical Center (S.F.), Boston, MA; NJ Neuroscience Institute (P.H.), Edison; University of California Irvine (N.H.); The University of Alabama at Birmingham (L.S.D.); and Massachusetts General Hospital (M.C.), Harvard Medical School, Boston.

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http://dx.doi.org/10.1212/WNL.0000000000003478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224719PMC
January 2017

Glial activation colocalizes with structural abnormalities in amyotrophic lateral sclerosis.

Neurology 2016 Dec 11;87(24):2554-2561. Epub 2016 Nov 11.

From A.A. Martinos Center for Biomedical Imaging, Department of Radiology (M.J.A., N.R.Z., M.L.L., D.B.C., D.I.G., C.C., B.R.R., J.M.H.), Neurological Clinical Research Institute, Department of Neurology (M.J.A., P.C., J.E.Y., M.E.C., N.A.), and Department of Anesthesiology (O.A.), Massachusetts General Hospital, Harvard Medical School, Charlestown.

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http://dx.doi.org/10.1212/WNL.0000000000003427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207001PMC
December 2016

Selecting Patients for Intra-Arterial Therapy in the Context of a Clinical Trial for Neuroprotection.

Stroke 2016 12 1;47(12):2979-2985. Epub 2016 Nov 1.

From the Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA (P.L.); ZZ Biotech, LLC, Houston, TX (S.W., H.L., K.P.); Department of Biostatistics, University of Iowa, Iowa City (C.C., S.O.); Neurological Clinical Research Institute, Massachusetts General Hospital, Boston (M.C., S.B.); Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA (M.F.); Department of Neurology, University of Virginia, Charlottesville (E.C.H.); Department of Neurology and Rehabilitation Medicine, University of Cincinnati, OH (P.K.); Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles (J.S.); Department of Neurology, State University of New York Downstate Medical Center, Brooklyn (S.L.); Department of Neurology, University of Kansas Hospital, Kansas City (M.R.); Department of Neurology, University of Pittsburgh Medical School, PA (L.W., A.J.); and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD (E.M., S.W.).

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http://dx.doi.org/10.1161/STROKEAHA.116.013881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134840PMC
December 2016

Race/ethnicity, socioeconomic status, and ALS mortality in the United States.

Neurology 2016 Nov 14;87(22):2300-2308. Epub 2016 Oct 14.

From the Departments of Social and Behavioral Sciences (A.L.R., J.T.C.), Environmental Health (M.G.W.), and Epidemiology (M.G.W.), Harvard T.H. Chan School of Public Health, Boston, MA; United States Census Bureau (N.J.J.), Washington, DC; Harvard Medical School (M.E.C.); and MGH Neurological Clinical Research Institute (M.E.C.), Department of Neurology, Massachusetts General Hospital, Boston.

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http://dx.doi.org/10.1212/WNL.0000000000003298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135021PMC
November 2016

Serum urate at trial entry and ALS progression in EMPOWER.

Amyotroph Lateral Scler Frontotemporal Degener 2017 02 28;18(1-2):120-125. Epub 2016 Sep 28.

e Department of Epidemiology and Nutrition , Harvard TH Chan School of Public Health, Boston, Massachusetts; Channing Division of Network Medicine, Harvard Medical School and Brigham and Women's Hospital , Boston , Massachusetts , USA.

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http://dx.doi.org/10.1080/21678421.2016.1214733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531275PMC
February 2017

Quantitative strength testing in ALS clinical trials.

Neurology 2016 Aug 6;87(6):617-24. Epub 2016 Jul 6.

From the Department of Neurology (J.M.S.), Barrow Neurological Institute, Phoenix, AZ; Biogen (D.L., M.L.L., D.R.J., T.F.), Cambridge; and Department of Neurology (D.S., M.C.), Massachusetts General Hospital, Boston.

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http://dx.doi.org/10.1212/WNL.0000000000002941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977369PMC
August 2016

Transplantation of spinal cord-derived neural stem cells for ALS: Analysis of phase 1 and 2 trials.

Neurology 2016 Jul 29;87(4):392-400. Epub 2016 Jun 29.

From the Departments of Neurology (J.D.G., M.P., J.B., C.F.) and Neurosurgery (N.M.B., J.R., T.F.), Emory University School of Medicine, Atlanta; Center for Nursing Data Science (V.S.H.), Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA; Neuralstem, Inc. (K.J., T.H.), Germantown, MD; Department of Neurology, Neurological Clinical Research Institute (M.C., N.A.), and Department of Neurosurgery (L.F.B.), Massachusetts General Hospital, Boston; Department of Neurology (S.B.R.), Beth Israel Hospital, Boston, MA; and Departments of Neurosurgery (P.G.P.) and Neurology (J.D., P.G.P., S.A.G., E.L.F.), University of Michigan, Ann Arbor, MI.

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http://dx.doi.org/10.1212/WNL.0000000000002889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977116PMC
July 2016

The Role of Environmental Toxins in Amyotrophic Lateral Sclerosis Risk.

JAMA Neurol 2016 07;73(7):779-80

Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, Massachusetts3Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamaneurol.2016.1038DOI Listing
July 2016

A randomized trial of mexiletine in ALS: Safety and effects on muscle cramps and progression.

Neurology 2016 Apr 24;86(16):1474-81. Epub 2016 Feb 24.

From the Department of Neurology (M.D.W., J.B.D.), University of Washington Medical Center, Seattle; Biostatistics Center (E.A.M.), Massachusetts General Hospital and Harvard Medical School, Boston; Department of Neurology (Z.S.), Penn State Hershey Medical Center, Hershey, PA; Department of Neurology (A.S.K., N.A., M.E.C.), Neurological Clinical Research Institute, Massachusetts General Hospital, Boston; Program in Pharmacology and Experimental Therapeutics (D.J.G.), Tufts University School of Medicine, Boston, MA; Department of Neurology (M.G., N.P.), UCLA Medical Center, Los Angeles, CA; Department of Neurology (J.S.S., C.Q., R.H.B.), University of Massachusetts Memorial Medical Center, Worcester; Department of Neurology (J.T.), University of Texas Southwestern Medical Center, Dallas; Department of Neurology (J.M.S.), Barrow Neurological Institute, Phoenix, AZ; Department of Neurology (R.J.B.), University of Kansas Medical Center, Kansas City; Department of Neurology (A.P.), Washington University Medical Center, St. Louis, MO; and Department of Neurology (A.S.), University of Iowa Hospitals and Clinics, Iowa City.

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http://dx.doi.org/10.1212/WNL.0000000000002507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836879PMC
April 2016

Preclinical Rodent Toxicity Studies for Long Term Use of Ceftriaxone.

Toxicol Rep 2015;2:1396-1403

Neurological Clinical Research Institute (NCRI), Massachusetts General Hospital, Boston, MA, Massachusetts General Hospital, 165 Cambridge Street, Suite 600, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.toxrep.2015.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685718PMC
January 2015

How common are ALS plateaus and reversals?

Neurology 2016 Mar 9;86(9):808-12. Epub 2015 Dec 9.

From the Department of Neurology (R.S.B.), Duke University and Durham VA Medical Center, Durham, NC; PatientsLikeMe (T.V., P.W., J.H.), Cambridge, MA; Massachusetts General Hospital (E.S., R.S., E.A.M., D.S., M.C., A.S.), Boston; and Harvard Medical School (E.A.M.), Boston, MA.

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http://dx.doi.org/10.1212/WNL.0000000000002251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793781PMC
March 2016

Military Service and Amyotrophic Lateral Sclerosis in a Population-based Cohort.

Epidemiology 2015 Nov;26(6):831-8

From the aDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA; bDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA; cDepartment of Neurology, Massachusetts General Hospital, Boston, MA; and dCenter for Administrative Records and Applications, US Bureau of the Census, Washington, DC.

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http://dx.doi.org/10.1097/EDE.0000000000000376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604116PMC
November 2015

Cortical Hyperexcitability in Amyotrophic Lateral Sclerosis: C9orf72 Repeats.

JAMA Neurol 2015 Nov;72(11):1235-6

Department of Neurology, Massachusetts General Hospital, Boston.

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http://dx.doi.org/10.1001/jamaneurol.2015.2197DOI Listing
November 2015

Job-related formaldehyde exposure and ALS mortality in the USA.

J Neurol Neurosurg Psychiatry 2016 07 13;87(7):786-8. Epub 2015 Jul 13.

Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/jnnp-2015-310750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738165PMC
July 2016

Reply: To PMID 25900666.

Muscle Nerve 2015 Oct 19;52(4):691. Epub 2015 Aug 19.

Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1002/mus.24760DOI Listing
October 2015

Transcranial magnetic stimulation of the brain: guidelines for pain treatment research.

Pain 2015 Sep;156(9):1601-14

aDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA bAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA cBerenson-Allen Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA dUS Food and Drug Administration, Center for Devices and Radiological Health, Division of Neurological and Physical Medicine Devices, Office of Device Evaluation, Bethesda, MD, USA eUS National Institutes of Health, National Institute on Mental Health, Experimental Therapeutics and Pathophysiology Branch, Bethesda, MD, USA fPain Research Institute, Neuroscience Research Centre, The Walton Centre NHS Foundation Trust, Liverpool, United Kingdom gDepartment of Neurosurgery, Johns Hopkins Medical Institutions, Baltimore, MD, USA hDepartment of Physiology, Henri Mondor Hospital, Assistance Publique - Hôpitaux de Paris, Créteil, France, iEA 4391, Nerve Excitability and Therapeutic Team, Faculty of Medicine, Paris Est Créteil University, Créteil, France, jHuman Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA, kDepartments of Anesthesiology, Medicine, and Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA, lDepartment of Pathology (Neuropathology), Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1097/j.pain.0000000000000210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545735PMC
September 2015

Pre-morbid type 2 diabetes mellitus is not a prognostic factor in amyotrophic lateral sclerosis.

Muscle Nerve 2015 Sep 1;52(3):339-43. Epub 2015 Jun 1.

Department of Neurology, Washington University School of Medicine, 115 Biotech Building, Box 8111, 660 South Euclid, Street, St. Louis, Missouri, 63110, USA.

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http://dx.doi.org/10.1002/mus.24688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536144PMC
September 2015

Randomized phase 2 trial of NP001-a novel immune regulator: Safety and early efficacy in ALS.

Neurol Neuroimmunol Neuroinflamm 2015 Jun 9;2(3):e100. Epub 2015 Apr 9.

California Pacific Medical Center (R.G.M., J.S.K.), San Francisco, CA; Neuraltus Pharmaceuticals, Inc. (G.B., V.G., M.S.M., A.A.), Palo Alto, CA; University of Kansas (R.J.B.), Kansas City; Massachusetts General Hospital (M.C.), Boston; University of California, San Francisco (R.Z., M.S.M.); Agility Clinical, Inc. (E.L.), Carlsbad, CA; and The Methodist Hospital (S.H.A.), Houston, TX.

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http://dx.doi.org/10.1212/NXI.0000000000000100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396529PMC
June 2015

Clinical Trial Designs in Amyotrophic Lateral Sclerosis: Does One Design Fit All?

Neurotherapeutics 2015 Apr;12(2):376-83

Massachusetts General Hospital, Department of Neurology, Neurological Clinical Research Institute, 165 Cambridge Street, Suite 600, Boston, MA, 02114, USA,

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http://dx.doi.org/10.1007/s13311-015-0341-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404442PMC
April 2015

Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: assessed with [(11)C]-PBR28.

Neuroimage Clin 2015 19;7:409-14. Epub 2015 Jan 19.

Neurological Clinical Research Institute (NCRI), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.nicl.2015.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310932PMC
September 2015

Disease burden in upper motor neuron syndromes: a survey of patient perspectives.

J Clin Neuromuscul Dis 2014 Dec;16(2):104-5

*Hospital for Special Care, New Britain, CT †University of Connecticut School of Medicine, Farmington, CT ‡Harvard Medical School, Department of Neurology, Neurological Clinical Research Institute (NCRI), Massachusetts General Hospital, Boston, MA §Harvard Medical School, Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Charlestown, MA ¶VA Boston Healthcare System, Boston, MA ‖Spastic Paraplegia Foundation, Falls Church, VA.

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http://dx.doi.org/10.1097/CND.0000000000000051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243581PMC
December 2014

Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.

Ann Neurol 2015 Jan 27;77(1):75-99. Epub 2014 Nov 27.

Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Evergrande Center for Immunologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02112.

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http://dx.doi.org/10.1002/ana.24304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432483PMC
January 2015

The PRO-ACT database: design, initial analyses, and predictive features.

Neurology 2014 Nov 8;83(19):1719-25. Epub 2014 Oct 8.

From the Neurological Clinical Research Institute (NCRI), Department of Neurology (N.A., J.B., A. Sherman, E.S., J.W., I.K., M.C.), and the Biostatistics Center (A. Shui, D.S.), Massachusetts General Hospital, Boston; and Prize4Life (N.Z., M.L.), Cambridge, MA.

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http://dx.doi.org/10.1212/WNL.0000000000000951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239834PMC
November 2014

Neuroprotective agents target molecular mechanisms of disease in ALS.

Drug Discov Today 2015 Jan 6;20(1):65-75. Epub 2014 Sep 6.

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2014.08.016DOI Listing
January 2015

Seeking a measure of clinically meaningful change in ALS.

Amyotroph Lateral Scler Frontotemporal Degener 2014 Sep 15;15(5-6):398-405. Epub 2014 Aug 15.

New York State Psychiatric Institute , New York, NY.

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http://www.tandfonline.com/doi/full/10.3109/21678421.2014.94
Publisher Site
http://dx.doi.org/10.3109/21678421.2014.942668DOI Listing
September 2014

Diagnostic timelines and delays in diagnosing amyotrophic lateral sclerosis (ALS).

Amyotroph Lateral Scler Frontotemporal Degener 2014 Sep 1;15(5-6):453-6. Epub 2014 Jul 1.

Department of Neurology, Harvard Medical School, Neurological Clinical Research Institute (NCRI), Massachusetts General Hospital , Boston, Massachusetts , USA.

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http://dx.doi.org/10.3109/21678421.2014.903974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433003PMC
September 2014

Locked in, but not out?

Neurology 2014 May 30;82(21):1852-3. Epub 2014 Apr 30.

From the Neurotechnology Trials Unit and the Neurological Clinical Trial Institute (L.R.H., M.E.C.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston; and the Center for Neurorestoration and Neurotechnology (L.R.H.), Rehabilitation Research and Development Service, Office of Research and Development, Department of Veterans Affairs, and Brown University School of Engineering and Institute for Brain Science, Providence, RI.

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http://dx.doi.org/10.1212/WNL.0000000000000460DOI Listing
May 2014

Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons.

Cell Rep 2014 Apr 3;7(1):1-11. Epub 2014 Apr 3.

FM Kirby Neurobiology Center, Boston Children's Hospital and Harvard Stem Cell Institute, Boston, MA 02115, USA; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.03.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023477PMC
April 2014

Predicting success: optimizing phase II ALS trials for the transition to phase III.

Amyotroph Lateral Scler Frontotemporal Degener 2014 Mar;15(1-2):1-8

Massachusetts General Hospital, Neurological Clinical Research Center , Boston, Massachusetts.

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http://dx.doi.org/10.3109/21678421.2013.838969DOI Listing
March 2014

Opportunities for improving therapy development in ALS.

Amyotroph Lateral Scler Frontotemporal Degener 2014 Jun 29;15(3-4):169-73. Epub 2014 Jan 29.

ALS Association , Washington, D.C.

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http://dx.doi.org/10.3109/21678421.2013.872662DOI Listing
June 2014

Outcome measures in amyotrophic lateral sclerosis clinical trials.

Clin Investig (Lond) 2014 ;4(7):605-618

Harvard Medical School, Department of Neurology, Neurological Clinical Research Institute (NCRI), Massachusetts Genera Hospital, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305182PMC
http://dx.doi.org/10.4155/cli.14.52DOI Listing
January 2014

Analysis of start-up, retention, and adherence in ALS clinical trials.

Neurology 2013 Oct 4;81(15):1350-5. Epub 2013 Sep 4.

From the Neurological Clinical Research Institute, Department of Neurology (N.A., P.Y.-R., H.Y., M.K., D.G., J.D., M.L.-W., J.S., A.L., L.J., M.E.C.), and Biostatistics Center (J.S., E.A.M.), Massachusetts General Hospital, Boston; and Harvard Medical School (N.A., P.Y.-R., E.A.M., M.E.C.), Boston, MA.

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http://dx.doi.org/10.1212/WNL.0b013e3182a823e0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806927PMC
October 2013

Post-lumbar puncture headache is reduced with use of atraumatic needles in ALS.

Amyotroph Lateral Scler Frontotemporal Degener 2013 Dec 8;14(7-8):632-4. Epub 2013 Jul 8.

Department of Neurology, University of Massachusetts, Memorial Medical Center , Worcester, Massachusetts.

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http://dx.doi.org/10.3109/21678421.2013.808227DOI Listing
December 2013

7-T MRI of the spinal cord can detect lateral corticospinal tract abnormality in amyotrophic lateral sclerosis.

Muscle Nerve 2013 May 29;47(5):760-2. Epub 2013 Mar 29.

AA Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA.

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http://dx.doi.org/10.1002/mus.23720DOI Listing
May 2013