Menna Clatworthy

Menna Clatworthy

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Menna Clatworthy

Publications by authors named "Menna Clatworthy"

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Mucosal IgG in inflammatory bowel disease - a question of (sub)class?

Gut Microbes 2019 Sep 3:1-9. Epub 2019 Sep 3.

Molecular Immunity Unit, Department of Medicine, University of Cambridge , Cambridge , UK.

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http://dx.doi.org/10.1080/19490976.2019.1651596DOI Listing
September 2019

Phenotypically distinct neutrophils patrol uninfected human and mouse lymph nodes.

Proc Natl Acad Sci U S A 2019 Sep 4;116(38):19083-19089. Epub 2019 Sep 4.

Molecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge CB2 0QH, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1905054116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754587PMC
September 2019

B Cell Fcγ Receptor IIb Modulates Atherosclerosis in Male and Female Mice by Controlling Adaptive Germinal Center and Innate B-1-Cell Responses.

Arterioscler Thromb Vasc Biol 2019 Jul 16;39(7):1379-1389. Epub 2019 May 16.

From the Division of Cardiovascular Medicine (J.B.-C., A.F., T.B., L.M., D.T., M.N., J.H., M.B., J.L., Z.M., A.P.S.), Department of Medicine, University of Cambridge, United Kingdom.

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http://dx.doi.org/10.1161/ATVBAHA.118.312272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636804PMC
July 2019

How to Find a Resident Kidney Macrophage: the Single-Cell Sequencing Solution.

J Am Soc Nephrol 2019 May 4;30(5):715-716. Epub 2019 Apr 4.

Molecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge, UK;

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http://dx.doi.org/10.1681/ASN.2019030245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493991PMC
May 2019

Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.

Immunity 2019 04 12;50(4):1099-1114.e10. Epub 2019 Mar 12.

Molecular Immunity Unit, University of Cambridge Department of Medicine, Cambridge CB2 0QH, UK; Cellular Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinton CB10 1SA, UK. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477154PMC
April 2019

IgG and Fcγ Receptors in Intestinal Immunity and Inflammation.

Front Immunol 2019 12;10:805. Epub 2019 Apr 12.

Molecular Immunity Unit, MRC Laboratory of Molecular Biology, Department of Medicine, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.3389/fimmu.2019.00805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473071PMC
April 2019

Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo.

Cell Chem Biol 2019 Mar 31;26(3):449-461.e8. Epub 2019 Jan 31.

MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK; Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2018.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436940PMC
March 2019

Belimumab in kidney transplantation - Authors' reply.

Lancet 2019 03;393(10174):875-876

Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge CB2 0SP, UK; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK; NIHR Cambridge Biomedical Research Centre, Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(18)33066-6DOI Listing
March 2019

A Systematic Review and Meta-Analysis of Alpha Synuclein Auto-Antibodies in Parkinson's Disease.

Front Neurol 2018 1;9:815. Epub 2018 Oct 1.

Department of Clinical Neurosciences, John van Geest Centre for Brain Repair, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.3389/fneur.2018.00815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176114PMC
October 2018

Monocyte Function in Parkinson's Disease and the Impact of Autologous Serum on Phagocytosis.

Front Neurol 2018 16;9:870. Epub 2018 Oct 16.

John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.3389/fneur.2018.00870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198066PMC
October 2018

Belimumab in kidney transplantation: an experimental medicine, randomised, placebo-controlled phase 2 trial.

Lancet 2018 06 14;391(10140):2619-2630. Epub 2018 Jun 14.

Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, UK; National Institute of Health Research (NIHR) Cambridge Biomedical Research Centre, Cambridge, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01406736183098
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http://dx.doi.org/10.1016/S0140-6736(18)30984-XDOI Listing
June 2018

Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone.

Cell 2017 Aug 10;170(5):860-874.e19. Epub 2017 Aug 10.

Molecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.07.022DOI Listing
August 2017

Fcγ Receptors in Solid Organ Transplantation.

Curr Transplant Rep 2016 3;3(4):284-293. Epub 2016 Oct 3.

Molecular Immunity Unit, Department of Medicine, MRC Laboratory of Molecular Biology, University of Cambridge, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, CB2 0QH UK.

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http://link.springer.com/10.1007/s40472-016-0116-7
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http://dx.doi.org/10.1007/s40472-016-0116-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107199PMC
October 2016

Novel immunotherapeutic strategies to target alloantibody-producing B and plasma cells in transplantation.

Curr Opin Organ Transplant 2016 08;21(4):419-26

Department of Medicine, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1097/MOT.0000000000000338DOI Listing
August 2016

Kidney Macrophages: Unique Position Solves a Complex Problem.

Cell 2016 Aug;166(4):799-801

University of Cambridge Department of Medicine, Molecular Immunity Unit, Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.07.047DOI Listing
August 2016

B cells in transplantation.

J Heart Lung Transplant 2016 06 12;35(6):704-10. Epub 2016 Feb 12.

Departments of Surgery and Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2016.01.1232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917469PMC
June 2016

FcγRIIB and autoimmunity.

Immunol Rev 2016 Jan;269(1):194-211

Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, UK.

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http://dx.doi.org/10.1111/imr.12368DOI Listing
January 2016

Two-photon microscopy for imaging germinal centers and T follicular helper cells.

Methods Mol Biol 2015 ;1291:63-75

Laboratory of Molecular Biology, Department of Medicine, University of Cambridge Research Unit, University of Cambridge, Cambridge Biomedical Campus, Francis Crick Avenue, Cambridge, CB2 0QH, UK,

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http://dx.doi.org/10.1007/978-1-4939-2498-1_6DOI Listing
December 2015

Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.

Nat Med 2014 Dec 10;20(12):1458-63. Epub 2014 Nov 10.

Laboratory of Systems Biology, Lymphocyte Biology Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/nm.3709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283039PMC
December 2014

FcγRIIb inhibits immune complex-induced VEGF-A production and intranodal lymphangiogenesis.

Proc Natl Acad Sci U S A 2014 Dec 4;111(50):17971-6. Epub 2014 Dec 4.

Department of Medicine, Cambridge Institute for Medical Research, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge CB2 0XY, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1413915111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273345PMC
December 2014

B-cell regulation and its application to transplantation.

Transpl Int 2014 Feb 4;27(2):117-28. Epub 2013 Aug 4.

Department of Medicine, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1111/tri.12160DOI Listing
February 2014

Elevated pretransplantation soluble BAFF is associated with an increased risk of acute antibody-mediated rejection.

Transplantation 2013 Aug;96(4):413-20

Department of Medicine, University of Cambridge, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, UK.

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http://dx.doi.org/10.1097/TP.0b013e318298dd65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170143PMC
August 2013

The Therapeutic Potential for PI3K Inhibitors in Autoimmune Rheumatic Diseases.

Open Rheumatol J 2012 7;6:245-58. Epub 2012 Sep 7.

Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Babraham Research Campus, CB22 3AT, UK.

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http://dx.doi.org/10.2174/1874312901206010245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460535PMC
July 2013

The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation.

Cell 2013 Apr;153(2):348-61

Lymphocyte Biology Section, Laboratory of Systems Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.cell.2013.02.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632354PMC
April 2013

Magnetic resonance imaging with hyperpolarized [1,4-(13)C2]fumarate allows detection of early renal acute tubular necrosis.

Proc Natl Acad Sci U S A 2012 Aug 26;109(33):13374-9. Epub 2012 Jul 26.

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge CB2 0XY, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1205539109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3421192PMC
August 2012

Immunotherapy for acute kidney injury.

Immunotherapy 2012 Mar;4(3):323-34

Division of Renal Medicine, Department of Medicine, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.2217/imt.11.175DOI Listing
March 2012

Biological therapy for lupus nephritis-tribulations and trials.

Nat Rev Rheumatol 2010 09 20;6(9):547-52. Epub 2010 Jul 20.

Department of Renal Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.

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http://dx.doi.org/10.1038/nrrheum.2010.117DOI Listing
September 2010

FcgammaRIIB in autoimmunity and infection: evolutionary and therapeutic implications.

Nat Rev Immunol 2010 May;10(5):328-43

Cambridge Institute for Medical Research and the Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1038/nri2762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148599PMC
May 2010

Ten-year experience of selective omission of the pretransplant crossmatch test in deceased donor kidney transplantation.

Transplantation 2010 Jan;89(2):185-93

Tissue Typing Laboratory, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Hills Road, Cambridge, United Kingdom.

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http://dx.doi.org/10.1097/TP.0b013e3181c926f2DOI Listing
January 2010

FcgammaRIIB, FcgammaRIIIB, and systemic lupus erythematosus.

Ann N Y Acad Sci 2010 Jan;1183:69-88

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1111/j.1749-6632.2009.05132.xDOI Listing
January 2010

Anti-CTLA-4 (CD 152) monoclonal antibody-induced autoimmune interstitial nephritis.

NDT Plus 2009 Aug 28;2(4):300-2. Epub 2009 Apr 28.

Renal Unit , Lister Hospital , Coreys Mill Lane, Stevenage, Hertfordshire SG1 4AB.

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http://dx.doi.org/10.1093/ndtplus/sfp048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421243PMC
August 2009

Low-affinity Fcgamma receptors, autoimmunity and infection.

Expert Rev Mol Med 2009 Aug 13;11:e24. Epub 2009 Aug 13.

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, CB2 0XY, UK.

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http://www.journals.cambridge.org/abstract_S1462399409001161
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http://dx.doi.org/10.1017/S1462399409001161DOI Listing
August 2009

Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis.

BMC Med Genet 2009 Mar 5;10:22. Epub 2009 Mar 5.

Cambridge Institute for Medical Research, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0XY, UK.

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http://dx.doi.org/10.1186/1471-2350-10-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662820PMC
March 2009

Vitiligo following a combined liver-kidney transplant.

Nephrol Dial Transplant 2009 Feb 28;24(2):686-8. Epub 2008 Nov 28.

Cambridge School of Clinical Medicine, University of Sheffield, UK.

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http://dx.doi.org/10.1093/ndt/gfn661DOI Listing
February 2009

Complement abnormalities in acquired lipodystrophy revisited.

J Clin Endocrinol Metab 2009 Jan 14;94(1):10-6. Epub 2008 Oct 14.

Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, United Kingdom.

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http://dx.doi.org/10.1210/jc.2008-1703DOI Listing
January 2009

Distinct cell-specific control of autoimmunity and infection by FcgammaRIIb.

J Exp Med 2008 Apr 24;205(4):883-95. Epub 2008 Mar 24.

Cambridge Institute for Medical Research and the Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge CB2 2OY, England, UK.

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http://dx.doi.org/10.1084/jem.20072565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292226PMC
April 2008

The calcified abdominal cocoon.

Lancet 2008 Apr;371(9622):1452

Department of Renal Medicine, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1016/S0140-6736(08)60625-XDOI Listing
April 2008

The nervous spleen: The nervous spleen.

Immunol Cell Biol 2008 Jan;86(1):1-2

Department of Medicine, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2XY, UK.

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http://doi.wiley.com/10.1038/sj.icb.7100150
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http://dx.doi.org/10.1038/sj.icb.7100150DOI Listing
January 2008

Subcutaneous administration of alemtuzumab in simultaneous pancreas-kidney transplantation.

Transplantation 2007 Dec;84(12):1563-7

Division of Renal Medicine, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.

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http://dx.doi.org/10.1097/01.tp.0000295718.55669.3aDOI Listing
December 2007

B cells in glomerulonephritis: focus on lupus nephritis.

Semin Immunopathol 2007 Nov 18;29(4):337-53. Epub 2007 Oct 18.

Division of Renal Medicine, Department of Medicine and Cambridge Institute for Medical Research, University of Cambridge, Lab 5.15, Box 139 Addenbrooke's Hospital, Cambridge, CB2 2XY, UK.

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http://dx.doi.org/10.1007/s00281-007-0092-1DOI Listing
November 2007

Systemic lupus erythematosus-associated defects in the inhibitory receptor FcgammaRIIb reduce susceptibility to malaria.

Proc Natl Acad Sci U S A 2007 Apr 13;104(17):7169-74. Epub 2007 Apr 13.

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge, Cambridge, United Kingdom.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0608889104
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http://dx.doi.org/10.1073/pnas.0608889104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855357PMC
April 2007

Neutrophils from patients with heterozygous germline mutations in the von Hippel Lindau protein (pVHL) display delayed apoptosis and enhanced bacterial phagocytosis.

Blood 2006 Nov 29;108(9):3176-8. Epub 2006 Jun 29.

Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's and Papworth Hospitals, Cambridge, United Kingdom.

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http://dx.doi.org/10.1182/blood-2006-04-018796DOI Listing
November 2006

Acquired hemophilia in association with ANCA-associated vasculitis: response to rituximab.

Am J Kidney Dis 2006 Apr;47(4):680-2

Lupus and Vasculitis Clinic, Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, UK.

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http://dx.doi.org/10.1053/j.ajkd.2006.01.009DOI Listing
April 2006

Loss of function of a lupus-associated FcgammaRIIb polymorphism through exclusion from lipid rafts.

Nat Med 2005 Oct 18;11(10):1056-8. Epub 2005 Sep 18.

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge, Cambridge CB2 2XY, UK.

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http://dx.doi.org/10.1038/nm1288DOI Listing
October 2005

SIGN-R1 contributes to protection against lethal pneumococcal infection in mice.

J Exp Med 2004 Dec;200(11):1383-93

Laboratory of Molecular Biology, Medical Research Council, Hills Rd., Cambridge CB2 2QH, England, UK.

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http://dx.doi.org/10.1084/jem.20040795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211941PMC
December 2004

FcgammaRIIb balances efficient pathogen clearance and the cytokine-mediated consequences of sepsis.

J Exp Med 2004 Mar 23;199(5):717-23. Epub 2004 Feb 23.

The Cambridge Institute for Medical Research, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, CB2 2XY, UK.

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http://www.jem.org/lookup/doi/10.1084/jem.20032197
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http://dx.doi.org/10.1084/jem.20032197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213308PMC
March 2004