Menghang Xia

Menghang Xia

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Human constitutive androstane receptor agonist DL5016: A novel sensitizer for cyclophosphamide-based chemotherapies.

Eur J Med Chem 2019 Oct 15;179:84-99. Epub 2019 Jun 15.

Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD, 21201, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2019.06.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718324PMC
October 2019

High-content analysis of constitutive androstane receptor (CAR) translocation identifies mosapride citrate as a CAR agonist that represses gluconeogenesis.

Biochem Pharmacol 2019 Oct 12;168:224-236. Epub 2019 Jul 12.

Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 Penn Street, Baltimore, MD 21201, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2019.07.013DOI Listing
October 2019

Limited Chemical Structural Diversity Found to Modulate Thyroid Hormone Receptor in the Tox21 Chemical Library.

Environ Health Perspect 2019 Sep 30;127(9):97009. Epub 2019 Sep 30.

National Center for Computational Toxicology, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1289/EHP5314DOI Listing
September 2019

Identifying Compounds with Genotoxicity Potential Using Tox21 High-Throughput Screening Assays.

Chem Res Toxicol 2019 Jul 18;32(7):1384-1401. Epub 2019 Jun 18.

Division of the National Toxicology Program , National Institute of Environmental Health Sciences , Research Triangle Park , North Carolina 27709 , United States.

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http://dx.doi.org/10.1021/acs.chemrestox.9b00053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6740247PMC
July 2019

DL5050, a Selective Agonist for the Human Constitutive Androstane Receptor.

ACS Med Chem Lett 2019 Jul 12;10(7):1039-1044. Epub 2019 Jun 12.

Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland 21201, United States.

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http://dx.doi.org/10.1021/acsmedchemlett.9b00079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627732PMC
July 2019

Use of high-throughput enzyme-based assay with xenobiotic metabolic capability to evaluate the inhibition of acetylcholinesterase activity by organophosphorous pesticides.

Toxicol In Vitro 2019 Apr 6;56:93-100. Epub 2019 Jan 6.

Division for Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08872333183054
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http://dx.doi.org/10.1016/j.tiv.2019.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713233PMC
April 2019

Using Tox21 High-Throughput Screening Assays for the Evaluation of Botanical and Dietary Supplements.

Appl In Vitro Toxicol 2019 Mar 9;5(1):10-25. Epub 2019 Mar 9.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.

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http://dx.doi.org/10.1089/aivt.2018.0020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442399PMC
March 2019

Identification of Compounds That Inhibit Estrogen-Related Receptor Alpha Signaling Using High-Throughput Screening Assays.

Molecules 2019 Feb 27;24(5). Epub 2019 Feb 27.

National Center for Advancing Translational Sciences, National Institutes of Health (NIH), Bethesda, MD 20814, USA.

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http://dx.doi.org/10.3390/molecules24050841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429183PMC
February 2019

Identification of Modulators That Activate the Constitutive Androstane Receptor From the Tox21 10K Compound Library.

Toxicol Sci 2019 01;167(1):282-292

Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland 20892.

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http://dx.doi.org/10.1093/toxsci/kfy242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657574PMC
January 2019

Triazole-Based Inhibitors of the Wnt/β-Catenin Signaling Pathway Improve Glucose and Lipid Metabolisms in Diet-Induced Obese Mice.

J Med Chem 2019 01 10;62(2):727-741. Epub 2019 Jan 10.

Department of Pharmaceutical Sciences , University of Maryland School of Pharmacy , Baltimore , Maryland 21201 , United States.

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http://dx.doi.org/10.1021/acs.jmedchem.8b01408DOI Listing
January 2019

Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.

ACS Cent Sci 2018 Dec 5;4(12):1727-1741. Epub 2018 Dec 5.

National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, United States.

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http://dx.doi.org/10.1021/acscentsci.8b00747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311695PMC
December 2018

Identification of Angiogenesis Inhibitors Using a Co-culture Cell Model in a High-Content and High-Throughput Screening Platform.

SLAS Technol 2018 06 18;23(3):217-225. Epub 2017 Sep 18.

1 Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1177/2472630317729792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032403PMC
June 2018

Detection of nanocarrier potentiation on drug induced phospholipidosis in cultured cells and primary hepatocyte spheroids by high content imaging and analysis.

Toxicol Appl Pharmacol 2018 06 18;348:54-66. Epub 2018 Apr 18.

School for Radiological and Interdisciplinary Sciences (RAD-X), State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou 215123, China. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2018.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716368PMC
June 2018

The Toxmatrix: Chemo-Genomic Profiling Identifies Interactions That Reveal Mechanisms of Toxicity.

Chem Res Toxicol 2018 02 4;31(2):127-136. Epub 2017 Dec 4.

National Center for Advancing Translational Sciences (NCATS), National Institutes of Health , 9800 Medical Center Drive, Bethesda, Maryland 20892, United States.

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http://dx.doi.org/10.1021/acs.chemrestox.7b00290DOI Listing
February 2018

Erythrosin B is a potent and broad-spectrum orthosteric inhibitor of the flavivirus NS2B-NS3 protease.

Antiviral Res 2018 02 27;150:217-225. Epub 2017 Dec 27.

Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12208, USA; Department of Biomedical Sciences, School of Public Health, University at Albany, PO Box 509, Empire State Plaza, Albany NY 12201, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01663542173045
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http://dx.doi.org/10.1016/j.antiviral.2017.12.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892443PMC
February 2018

Expanding biological space coverage enhances the prediction of drug adverse effects in human using in vitro activity profiles.

Sci Rep 2018 02 28;8(1):3783. Epub 2018 Feb 28.

Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD, 20850, USA.

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http://dx.doi.org/10.1038/s41598-018-22046-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830476PMC
February 2018

Mitochondrial Membrane Potential Assay.

Methods Mol Biol 2016 ;1473:17-22

National Center for Advancing Translational Sciences, National Institutes of Health, Building C, MSC: 3375, 9800 Medical Center Drive, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/978-1-4939-6346-1_2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375165PMC
January 2018

Using β-Lactamase and NanoLuc Luciferase Reporter Gene Assays to Identify Inhibitors of the HIF-1 Signaling Pathway.

Methods Mol Biol 2016 ;1473:23-31

National Center for Advancing Translational Sciences, National Institutes of Health, Building C, MSC: 3375, 9800 Medical Center Drive, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/978-1-4939-6346-1_3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375166PMC
January 2018

Quantitative High-Throughput Luciferase Screening in Identifying CAR Modulators.

Methods Mol Biol 2016 ;1473:33-42

National Center for Advancing Translational Sciences, National Institutes of Health, Building C, MSC: 3375, 9800 Medical Center Drive, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/978-1-4939-6346-1_4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341601PMC
January 2018

Transactivation and Coactivator Recruitment Assays for Measuring Farnesoid X Receptor Activity.

Methods Mol Biol 2016 ;1473:43-53

National Center for Advancing Translational Sciences, National Institutes of Health, Building C, MSC: 3375, 9800 Medical Center Drive, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/978-1-4939-6346-1_5DOI Listing
January 2018

Cell-Based Assay for Identifying the Modulators of Antioxidant Response Element Signaling Pathway.

Methods Mol Biol 2016 ;1473:55-62

National Center for Advancing Translational Sciences, National Institutes of Health, Building C, MSC: 3375, 9800 Medical Center Drive, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/978-1-4939-6346-1_6DOI Listing
January 2018

Determination of Histone H2AX Phosphorylation in DT40 Cells.

Methods Mol Biol 2016 ;1473:71-6

National Center for Advancing Translational Sciences, National Institutes of Health, Building C, MSC: 3375, 9800 Medical Center Drive, Bethesda, MD, 20892, USA.

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http://link.springer.com/10.1007/978-1-4939-6346-1_8
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http://dx.doi.org/10.1007/978-1-4939-6346-1_8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375169PMC
January 2018

High-Throughput and High-Content Micronucleus Assay in CHO-K1 Cells.

Methods Mol Biol 2016 ;1473:77-85

National Center for Advancing Translational Sciences, National Institutes of Health, Building C, MSC: 3375, 9800 Medical Center Drive, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/978-1-4939-6346-1_9DOI Listing
January 2018

Omics-Based Platform for Studying Chemical Toxicity Using Stem Cells.

J Proteome Res 2018 01 20;17(1):579-589. Epub 2017 Dec 20.

Newomics Inc. , Emeryville, California 94608, United States.

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http://dx.doi.org/10.1021/acs.jproteome.7b00693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756105PMC
January 2018

Why are most phospholipidosis inducers also hERG blockers?

Arch Toxicol 2017 Dec 27;91(12):3885-3895. Epub 2017 May 27.

Division of Systems Biology, National Center for Toxicological Research, 3900 NCTR Road, Jefferson, AR, 72079, USA.

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http://link.springer.com/10.1007/s00204-017-1995-9
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http://dx.doi.org/10.1007/s00204-017-1995-9DOI Listing
December 2017

Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage.

PLoS One 2017 22;12(5):e0177902. Epub 2017 May 22.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177902PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439695PMC
September 2017

Assessment of the DNA damaging potential of environmental chemicals using a quantitative high-throughput screening approach to measure p53 activation.

Environ Mol Mutagen 2017 08 17;58(7):494-507. Epub 2017 Jul 17.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.

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http://dx.doi.org/10.1002/em.22112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555817PMC
August 2017

Monohalogenated acetamide-induced cellular stress and genotoxicity are related to electrophilic softness and thiol/thiolate reactivity.

J Environ Sci (China) 2017 Aug 9;58:224-230. Epub 2017 May 9.

Department of Environmental and Occupational Health, Milken Institute School of Public Health, George Washington University, Washington, DC, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jes.2017.04.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239421PMC
August 2017

In Silico Prediction of hPXR Activators Using Structure-Based Pharmacophore Modeling.

J Pharm Sci 2017 07 16;106(7):1752-1759. Epub 2017 Mar 16.

Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850.

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https://linkinghub.elsevier.com/retrieve/pii/S00223549173016
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http://dx.doi.org/10.1016/j.xphs.2017.03.004DOI Listing
July 2017

Development of Novel Cell Lines for High-Throughput Screening to Detect Estrogen-Related Receptor Alpha Modulators.

SLAS Discov 2017 07 31;22(6):720-731. Epub 2017 Jan 31.

1 Division of the National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, Durham, NC, USA.

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http://dx.doi.org/10.1177/2472555216689772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486949PMC
July 2017

Identification of acetylcholinesterase inhibitors using homogenous cell-based assays in quantitative high-throughput screening platforms.

Biotechnol J 2017 May 6;12(5). Epub 2017 Apr 6.

Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1002/biot.201600715DOI Listing
May 2017

Prediction of hERG Liability - Using SVM Classification, Bootstrapping and Jackknifing.

Mol Inform 2017 04 21;36(4). Epub 2016 Dec 21.

National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1002/minf.201600126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382096PMC
April 2017

Characterization of three human cell line models for high-throughput neuronal cytotoxicity screening.

J Appl Toxicol 2017 02 3;37(2):167-180. Epub 2016 May 3.

National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, Rockville, MD, USA.

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http://doi.wiley.com/10.1002/jat.3334
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http://dx.doi.org/10.1002/jat.3334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094908PMC
February 2017

Development and Application of Human Renal Proximal Tubule Epithelial Cells for Assessment of Compound Toxicity.

Curr Chem Genom Transl Med 2017 14;11:19-30. Epub 2017 Feb 14.

9800 Medical Center Drive, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892-3375, USA.

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http://benthamopen.com/ABSTRACT/CCGTM-11-19
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http://dx.doi.org/10.2174/2213988501711010019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362976PMC
February 2017

One-Step Seeding of Neural Stem Cells with Vitronectin-Supplemented Medium for High-Throughput Screening Assays.

J Biomol Screen 2016 Dec 26;21(10):1112-1124. Epub 2016 Sep 26.

1 National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1177/1087057116670068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285267PMC
December 2016

Differential modulation of FXR activity by chlorophacinone and ivermectin analogs.

Toxicol Appl Pharmacol 2016 12 20;313:138-148. Epub 2016 Oct 20.

NIH Chemical Genomics Center, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2016.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124510PMC
December 2016

Corrigendum to Performance of the BG1Luc ER TA method in a qHTS format.

ALTEX 2016 ;33(1):79

National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.14573/altex.1512041DOI Listing
August 2016

A cell-based quantitative high-throughput image screening identified novel autophagy modulators.

Pharmacol Res 2016 08 7;110:35-49. Epub 2016 May 7.

Department of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, KS 66160, USA. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2016.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995889PMC
August 2016

Identification of HDAC Inhibitors Using a Cell-Based HDAC I/II Assay.

J Biomol Screen 2016 Jul 8;21(6):643-52. Epub 2016 Feb 8.

National Center for Advancing Translational Sciences, Bethesda, MD, USA

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http://dx.doi.org/10.1177/1087057116629381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917448PMC
July 2016

A Novel Chemotherapeutic Agent to Treat Tumors with DNA Mismatch Repair Deficiencies.

Cancer Res 2016 07 4;76(14):4183-91. Epub 2016 Jun 4.

Genome Instability Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland. Center for Genomic Integrity, Institute for Basic Science, Ulsan, Korea. Department of Biological Sciences, School of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan, Korea.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-2974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033673PMC
July 2016

Performance of the BG1Luc ER TA method in a qHTS format.

ALTEX 2015 28;32(4):287-96. Epub 2015 Jun 28.

National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.14573/altex.1505121DOI Listing
June 2016

High-Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress.

Stem Cells Transl Med 2016 May 31;5(5):613-27. Epub 2016 Mar 31.

National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, USA

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http://dx.doi.org/10.5966/sctm.2015-0170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835244PMC
May 2016

Identification of compounds that modulate retinol signaling using a cell-based qHTS assay.

Toxicol In Vitro 2016 Apr 25;32:287-96. Epub 2016 Jan 25.

National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892, United States.

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http://dx.doi.org/10.1016/j.tiv.2016.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779714PMC
April 2016

Identification of approved and investigational drugs that inhibit hypoxia-inducible factor-1 signaling.

Oncotarget 2016 Feb;7(7):8172-83

Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.18632/oncotarget.6995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884984PMC
February 2016

Identification of genotoxic compounds using isogenic DNA repair deficient DT40 cell lines on a quantitative high throughput screening platform.

Mutagenesis 2016 Jan 4;31(1):69-81. Epub 2015 Aug 4.

National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, MSC: 3375 Bethesda, MD 20892, USA and

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http://dx.doi.org/10.1093/mutage/gev055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723671PMC
January 2016

Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization.

Nat Commun 2016 Jan 26;7:10425. Epub 2016 Jan 26.

Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, USA.

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http://dx.doi.org/10.1038/ncomms10425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777217PMC
January 2016

Predictive endocrine testing in the 21st century using in vitro assays of estrogen receptor signaling responses.

Environ Sci Technol 2014 10;48(15):8706-16. Epub 2014 Jul 10.

Department of Environmental Sciences and Engineering, University of North Carolina , Chapel Hill, North Carolina 27514, United States.

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http://dx.doi.org/10.1021/es502676eDOI Listing
November 2015

Evaluation of CYP3A4 inhibition and hepatotoxicity using DMSO-treated human hepatoma HuH-7 cells.

Cell Biol Toxicol 2015 Oct 16;31(4-5):221-30. Epub 2015 Sep 16.

Division of Public Health Informatics & Analytics, Office of Analytics and Outreach, Center for Food Safety and Applied Nutrition, US Food and Drug Administration, College Park, MD, USA.

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http://dx.doi.org/10.1007/s10565-015-9306-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970208PMC
October 2015

A Data Analysis Pipeline Accounting for Artifacts in Tox21 Quantitative High-Throughput Screening Assays.

J Biomol Screen 2015 Aug 22;20(7):887-97. Epub 2015 Apr 22.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.

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http://dx.doi.org/10.1177/1087057115581317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568956PMC
August 2015

Human cell toxicogenomic analysis linking reactive oxygen species to the toxicity of monohaloacetic acid drinking water disinfection byproducts.

Environ Sci Technol 2013 10;47(21):12514-23. Epub 2013 Oct 10.

Department of Crop Sciences, University of Illinois at Urbana-Champaign , Urbana, Illinois, United States.

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http://dx.doi.org/10.1021/es403171bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014314PMC
July 2015

Identification of known drugs targeting the endoplasmic reticulum stress response.

Anal Bioanal Chem 2015 Jul 30;407(18):5343-51. Epub 2015 Apr 30.

Life Science Solutions Group, Thermo Fisher Scientific, Rockford, IL, 61105, USA.

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http://link.springer.com/content/pdf/10.1007%2Fs00216-015-86
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http://link.springer.com/10.1007/s00216-015-8694-2
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http://dx.doi.org/10.1007/s00216-015-8694-2DOI Listing
July 2015

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.

Authors:
William H Goodson Leroy Lowe David O Carpenter Michael Gilbertson Abdul Manaf Ali Adela Lopez de Cerain Salsamendi Ahmed Lasfar Amancio Carnero Amaya Azqueta Amedeo Amedei Amelia K Charles Andrew R Collins Andrew Ward Anna C Salzberg Annamaria Colacci Ann-Karin Olsen Arthur Berg Barry J Barclay Binhua P Zhou Carmen Blanco-Aparicio Carolyn J Baglole Chenfang Dong Chiara Mondello Chia-Wen Hsu Christian C Naus Clement Yedjou Colleen S Curran Dale W Laird Daniel C Koch Danielle J Carlin Dean W Felsher Debasish Roy Dustin G Brown Edward Ratovitski Elizabeth P Ryan Emanuela Corsini Emilio Rojas Eun-Yi Moon Ezio Laconi Fabio Marongiu Fahd Al-Mulla Ferdinando Chiaradonna Firouz Darroudi Francis L Martin Frederik J Van Schooten Gary S Goldberg Gerard Wagemaker Gladys N Nangami Gloria M Calaf Graeme Williams Gregory T Wolf Gudrun Koppen Gunnar Brunborg H Kim Lyerly Harini Krishnan Hasiah Ab Hamid Hemad Yasaei Hideko Sone Hiroshi Kondoh Hosni K Salem Hsue-Yin Hsu Hyun Ho Park Igor Koturbash Isabelle R Miousse A Ivana Scovassi James E Klaunig Jan Vondráček Jayadev Raju Jesse Roman John Pierce Wise Jonathan R Whitfield Jordan Woodrick Joseph A Christopher Josiah Ochieng Juan Fernando Martinez-Leal Judith Weisz Julia Kravchenko Jun Sun Kalan R Prudhomme Kannan Badri Narayanan Karine A Cohen-Solal Kim Moorwood Laetitia Gonzalez Laura Soucek Le Jian Leandro S D'Abronzo Liang-Tzung Lin Lin Li Linda Gulliver Lisa J McCawley Lorenzo Memeo Louis Vermeulen Luc Leyns Luoping Zhang Mahara Valverde Mahin Khatami Maria Fiammetta Romano Marion Chapellier Marc A Williams Mark Wade Masoud H Manjili Matilde E Lleonart Menghang Xia Michael J Gonzalez Michalis V Karamouzis Micheline Kirsch-Volders Monica Vaccari Nancy B Kuemmerle Neetu Singh Nichola Cruickshanks Nicole Kleinstreuer Nik van Larebeke Nuzhat Ahmed Olugbemiga Ogunkua P K Krishnakumar Pankaj Vadgama Paola A Marignani Paramita M Ghosh Patricia Ostrosky-Wegman Patricia A Thompson Paul Dent Petr Heneberg Philippa Darbre Po Sing Leung Pratima Nangia-Makker Qiang Shawn Cheng R Brooks Robey Rabeah Al-Temaimi Rabindra Roy Rafaela Andrade-Vieira Ranjeet K Sinha Rekha Mehta Renza Vento Riccardo Di Fiore Richard Ponce-Cusi Rita Dornetshuber-Fleiss Rita Nahta Robert C Castellino Roberta Palorini Roslida Abd Hamid Sabine A S Langie Sakina E Eltom Samira A Brooks Sandra Ryeom Sandra S Wise Sarah N Bay Shelley A Harris Silvana Papagerakis Simona Romano Sofia Pavanello Staffan Eriksson Stefano Forte Stephanie C Casey Sudjit Luanpitpong Tae-Jin Lee Takemi Otsuki Tao Chen Thierry Massfelder Thomas Sanderson Tiziana Guarnieri Tove Hultman Valérian Dormoy Valerie Odero-Marah Venkata Sabbisetti Veronique Maguer-Satta W Kimryn Rathmell Wilhelm Engström William K Decker William H Bisson Yon Rojanasakul Yunus Luqmani Zhenbang Chen Zhiwei Hu

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