Mena Abdelsayed

Mena Abdelsayed

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Mena Abdelsayed

Mena Abdelsayed

Publications by authors named "Mena Abdelsayed"

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12Publications

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The efficacy of Ranolazine on E1784K is altered by temperature and calcium.

Sci Rep 2018 02 26;8(1):3643. Epub 2018 Feb 26.

Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, V5A 1S6, Canada.

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http://dx.doi.org/10.1038/s41598-018-22033-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827758PMC
February 2018

Arrhythmogenic triggers associated with Sudden Cardiac Death.

Channels (Austin) 2018 01 13;12(1):76-77. Epub 2017 Nov 13.

a Department of Biomedical Physiology and Kinesiology , Simon Fraser University , Burnaby , British Columbia , Canada.

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http://dx.doi.org/10.1080/19336950.2017.1388057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972799PMC
January 2018

Differential calcium sensitivity in Na 1.5 mixed syndrome mutants.

J Physiol 2017 09 20;595(18):6165-6186. Epub 2017 Aug 20.

Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, Canada.

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http://dx.doi.org/10.1113/JP274536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599485PMC
September 2017

Exome Sequencing and the Management of Neurometabolic Disorders.

N Engl J Med 2016 Jun 25;374(23):2246-55. Epub 2016 May 25.

From the Centre for Molecular Medicine and Therapeutics (M.T.-G., C. Shyr, X.C.Y., L.-H.Z., J.J.Y.L., B.I.D., I.G., W.W.W., C.D.K.), the Departments of Medical Genetics (M.T.-G., C. Shyr, C.J.R., X.C.Y., J.J.Y.L., L.A., J.M.F., S.L., M.M., M.I.V.A., A.M.L., W.W.W.), Pediatrics (C.J.R., G.A.H., R.S., L.-H.Z., A.P.B., B.I.D., M.B.C., M.D., T.D., J.D., A. Michoulas, D.M., J.R., K.R.S., K.S., S.E.T., John Wu, S.S.-I., C.D.K.), and Pathology and Laboratory Medicine (B.R., P.E., H.V., G.S.), the Child and Family Research Institute (M.T.-G., C. Shyr, C.J.R., G.A.H., X.C.Y., A.P.B., J.J.Y.L., B.I.D., L.A., M.B.C., M.D., J.D., J.M.F., I.G., S.L., M.M., D.M., J.R., K.R.S., K.S., S.E.T., M.I.V.A., John Wu, P.E., A.M.L., H.V., S.S.-I., G.S., W.W.W., C.D.K.), and the Division of Endocrinology, Adult Metabolic Diseases Clinic (A. Mattman, S. Sirrs), University of British Columbia, and the Divisions of Biochemical Diseases (G.A.H., R.S., B.S., S.S.-I., C.D.K.), Pediatric Neurology (M.B.C., M.D., A. Michoulas, K.S.), Pediatric Nephrology (J.D.), Pediatric Endocrinology (D.M.), and Immunology (S.E.T.) and the Division of Hematology, Oncology and Transplantation, Michael Cuccione Childhood Cancer Research Program (J.R., K.R.S., John Wu), BC Children's Hospital, Vancouver, the Department of Pathology and Laboratory Medicine, Hospital for Sick Children, University of Toronto, Toronto (J.C.), the Department of Biological and Computing Sciences, University of Alberta (R.M., D.W.), and the National Institute for Nanotechnology (D.W.), Edmonton, AB, and the Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, BC (M. Abdelsayed, P.R.) - all in Canada; the Division of Genetics, Department of Pediatrics, King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi Arabia (M. Alfadhel); the Division of Metabolism and Children's Research Center, University Children's Hospital Zurich, Zurich (M.R.B., P.B.), and the Departmen

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http://dx.doi.org/10.1056/NEJMoa1515792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983272PMC
June 2016

Effects of Amiodarone and N-desethylamiodarone on Cardiac Voltage-Gated Sodium Channels.

Front Pharmacol 2016 1;7:39. Epub 2016 Mar 1.

Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby BC, Canada.

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http://dx.doi.org/10.3389/fphar.2016.00039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771766PMC
March 2016

Triggers for arrhythmogenesis in the Brugada and long QT 3 syndromes.

Prog Biophys Mol Biol 2016 Jan 20;120(1-3):77-88. Epub 2015 Dec 20.

Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, V5A1S6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pbiomolbio.2015.12.009DOI Listing
January 2016

Differential thermosensitivity in mixed syndrome cardiac sodium channel mutants.

J Physiol 2015 Sep 12;593(18):4201-23. Epub 2015 Aug 12.

Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada, V5A 1S6.

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http://dx.doi.org/10.1113/JP270139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594293PMC
September 2015

Voltage-gated sodium channels: pharmaceutical targets via anticonvulsants to treat epileptic syndromes.

Channels (Austin) 2013 May-Jun;7(3):146-52. Epub 2013 Mar 26.

Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, BC, Canada.

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http://dx.doi.org/10.4161/chan.24380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710341PMC
October 2014

A thermosensitive mutation alters the effects of lacosamide on slow inactivation in neuronal voltage-gated sodium channels, NaV1.2.

Front Pharmacol 2013 20;4:121. Epub 2013 Sep 20.

Department of Biomedical Physiology and Kinesiology, Simon Fraser University Burnaby, BC, Canada.

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http://dx.doi.org/10.3389/fphar.2013.00121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778253PMC
September 2013