Melyssa Aronson

Melyssa Aronson

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Melyssa Aronson

Melyssa Aronson

Publications by authors named "Melyssa Aronson"

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58Publications

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Cost-effectiveness of Active Identification and Subsequent Colonoscopy Surveillance of Lynch Syndrome Cases.

Clin Gastroenterol Hepatol 2019 Oct 17. Epub 2019 Oct 17.

Department of Surgery, LiKaShing Knowledge Institute St. Michael's Hospital, Toronto, Canada.

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http://dx.doi.org/10.1016/j.cgh.2019.10.021DOI Listing
October 2019

The impact of health anxiety on perceptions of personal and children's health in parents with Lynch syndrome.

J Genet Couns 2019 Jun 14;28(3):495-506. Epub 2019 Jan 14.

Department of Psychology, Ryerson University, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/jgc4.1043DOI Listing
June 2019

Delineating a new feature of constitutional mismatch repair deficiency (CMMRD) syndrome: breast cancer.

Fam Cancer 2019 01;18(1):105-108

Department of Medical Affairs, Ambry Genetics, 15 Argonaut, Aliso Viejo, CA, 92656, USA.

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http://link.springer.com/10.1007/s10689-018-0088-0
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http://dx.doi.org/10.1007/s10689-018-0088-0DOI Listing
January 2019

Association between the Lynch syndrome gene MSH2 and breast cancer susceptibility in a Canadian familial cancer registry.

J Med Genet 2017 11 4;54(11):742-746. Epub 2017 Aug 4.

Department of Oncology, McMaster University, Hamilton, Canada.

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http://dx.doi.org/10.1136/jmedgenet-2017-104542DOI Listing
November 2017

Comprehensive Analysis of Hypermutation in Human Cancer.

Cell 2017 Nov 19;171(5):1042-1056.e10. Epub 2017 Oct 19.

Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada; Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.09.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849393PMC
November 2017

Lack of evidence for germline mutations in patients with serrated polyposis syndrome from a large multinational study.

Gut 2017 06 31;66(6):1170-1172. Epub 2016 Aug 31.

Colorectal Oncogenomics Group, Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1136/gutjnl-2016-312773DOI Listing
June 2017

Prophylactic Total Gastrectomy: a Prospective Cohort Study of Long-Term Impact on Quality of Life.

J Gastrointest Surg 2016 12 17;20(12):1950-1958. Epub 2016 Oct 17.

Department of Surgery, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s11605-016-3287-8DOI Listing
December 2016

Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency.

J Clin Oncol 2016 07 21;34(19):2206-11. Epub 2016 Mar 21.

Eric Bouffet, Brittany B. Campbell, Daniele Merico, Richard de Borja, Carol Durno, Joerg Krueger, Vanja Cabric, Vijay Ramaswamy, Nataliya Zhukova, Peter Dirks, Michael Taylor, David Malkin, Cynthia E. Hawkins, Adam Shlien, and Uri Tabori, The Hospital for Sick Children, Toronto; Melyssa Aronson, and Zane Cohen, Zane Cohen Centre for Digestive Diseases, Mount Sinai, Ontario; Valérie Larouche and Rachel Laframboise, Université Laval, Quebec City; Jeffrey Atkinson, Montreal Children's Hospital; Steffen Albrecht, Roy W.R. Dudley, and Nada Jabado, McGill University, Montreal, Montreal, Quebec; Samina Afzal, IWK Health Centre, Halifax, Nova Scotia; Vanan Magimairajan, Cancer Care Manitoba and University of Manitoba, Winnipeg, Manitoba, Canada; Gary Mason, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA; Roula Farah, Saint George Hospital University Medical Center, Beirut, Lebanon; Michal Yalon and Gideon Rechavi, Sheba Medical Center, Tel Hashomer; Shlomi Constantini, Rina Dvir, and Ronit Elhasid, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Michael F. Walsh, Memorial Sloan Kettering Center, New York, NY; Alyssa Reddy, University of Alabama at Birmingham, Birmingham, AL; Michael Osborn, Women's and Children's Hospital, North Adelaide, South Australia; Michael Sullivan, Jordan Hansford, and Andrew Dodgshun, Royal Children's Hospital, Melbourne, Victoria, Australia; and Nancy Klauber-Demore, Lindsay Peterson, Sunil Patel, and Scott Lindhorst, Medical University of South Carolina, Charleston, SC.

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http://dx.doi.org/10.1200/JCO.2016.66.6552DOI Listing
July 2016

Cancer Worry, Perceived Risk and Cancer Screening in First-Degree Relatives of Patients with Familial Gastric Cancer.

J Genet Couns 2016 06 22;25(3):520-8. Epub 2015 Oct 22.

Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1007/s10897-015-9903-zDOI Listing
June 2016

Physician trust moderates the relationship between intolerance of uncertainty and cancer worry interference among women with Lynch syndrome.

J Behav Med 2016 06 13;39(3):420-8. Epub 2016 Jan 13.

Department of Psychology, Ryerson University, 350 Victoria Street, Toronto, ON, M5B2K3, Canada.

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http://dx.doi.org/10.1007/s10865-016-9711-4DOI Listing
June 2016

Is there a role for prophylactic colectomy in Lynch syndrome patients with inflammatory bowel disease?

Int J Colorectal Dis 2016 Jan 28;31(1):9-13. Epub 2015 Sep 28.

Lunenfeld-Tanenbaum Research Institute, 60 Murray Street Box 31 Rm L6-304G, Toronto, ON, M5T3L9, Canada.

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http://dx.doi.org/10.1007/s00384-015-2398-0DOI Listing
January 2016

Management of Acute Myeloblastic Leukemia in a Child With Biallelic Mismatch Repair Deficiency.

J Pediatr Hematol Oncol 2015 Nov;37(8):e490-3

*Department of Pediatric Hemato-Oncology †The Gilbert Israeli Neurofibromatosis Center (GINFC) ‡Department of Pathology, Diagnostic and Research Cancer Center, Tel Aviv Sourasky Medical Center, Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel §Division of Hematology/Oncology, Institute of Medical Sciences ¶Department of Laboratory Medicine and Pathobiology, Division of Pathology, The Hospital for Sick Children, The University of Toronto ∥Zane Cohen Centre, Mount Sinai Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/MPH.0000000000000415DOI Listing
November 2015

Phenotypic and genotypic characterisation of biallelic mismatch repair deficiency (BMMR-D) syndrome.

Eur J Cancer 2015 May 13;51(8):977-83. Epub 2015 Apr 13.

Division of Haematology/Oncology, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.ejca.2015.02.008DOI Listing
May 2015

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers.

Nat Genet 2015 Mar 2;47(3):257-62. Epub 2015 Feb 2.

1] Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada. [2] The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada. [3] Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada. [4] Department of Pediatrics, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/ng.3202DOI Listing
March 2015

Performance characteristics of a brief Family History Questionnaire to screen for Lynch syndrome in women with newly diagnosed endometrial cancer.

Gynecol Oncol 2015 Feb 19;136(2):311-6. Epub 2014 Dec 19.

Division of Gynecologic Oncology, Princess Margaret Hospital/University Health Network, 610 University Ave., Toronto, Ontario M5G 2M9, Canada; Department of Obstetrics and Gynecology, University of Toronto, 27 King's College Circle, Toronto, Ontario M5S 2J7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2014.12.023DOI Listing
February 2015

Performance characteristics of screening strategies for Lynch syndrome in unselected women with newly diagnosed endometrial cancer who have undergone universal germline mutation testing.

Cancer 2014 Dec 31;120(24):3932-9. Epub 2014 Jul 31.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Princess Margaret Hospital/University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/cncr.28933DOI Listing
December 2014

The histomorphology of Lynch syndrome-associated ovarian carcinomas: toward a subtype-specific screening strategy.

Am J Surg Pathol 2014 Sep;38(9):1173-81

Departments of *Laboratory Medicine and Pathobiology ‡Obstetrics and Gynecology, Faculty of Medicine, University of Toronto §Division of Gynecologic Oncology §§Department of Pathology, University Health Network ∥Department of Laboratory Medicine and Pathology ¶Zane Cohen Centre for Digestive Diseases, Familial Gastrointestinal Cancer Registry ‡‡Division of General Surgery, Mount Sinai Hospital, Toronto, ON ∥∥Department of Medical Genetics, McGill University Health Centre, Montreal, QB #Division of Gynecologic Oncology ¶¶Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia and BC Cancer Agency, Vancouver, BC, Canada †Department of Pathology, Bon Secours Hospital, Cork, Ireland **Department of Histopathology, King Edward Memorial Hospital for Women, Perth, Australia ††Department of Cellular Pathology, Barts Health NHS Trust, London, United Kingdom.

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http://pdfs.journals.lww.com/ajsp/2014/09000/The_Histomorpho
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PAS.0000000000000298DOI Listing
September 2014

Genetic and clinical determinants of constitutional mismatch repair deficiency syndrome: report from the constitutional mismatch repair deficiency consortium.

Eur J Cancer 2014 Mar 15;50(5):987-96. Epub 2014 Jan 15.

Division of Hematology/Oncology, The Hospital for Sick Children, Institute of Medical Sciences, The University of Toronto, Toronto, Ontario, Canada; Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada; Arthur and Sonia Labbatt Brain Tumor Research Center, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2013.12.005DOI Listing
March 2014

Oncologic surveillance for subjects with biallelic mismatch repair gene mutations: 10 year follow-up of a kindred.

Pediatr Blood Cancer 2012 Oct 16;59(4):652-6. Epub 2011 Dec 16.

The Familial Gastrointestinal Cancer Registry at Zane Cohen Centre for Digestive Diseases and Department of Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/pbc.24019DOI Listing
October 2012

A novel complex mutation in MSH2 contributes to both Muir-Torre and Lynch Syndrome.

J Hum Genet 2010 Jan 13;55(1):37-41. Epub 2009 Nov 13.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/jhg.2009.119DOI Listing
January 2010

Genetic counseling for hereditary colorectal cancer: ethical, legal, and psychosocial issues.

Authors:
Melyssa Aronson

Surg Oncol Clin N Am 2009 Oct;18(4):669-85

Department of Surgery, Mount Sinai Hospital, Toronto, Ontario M5T 3L9, Canada.

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http://dx.doi.org/10.1016/j.soc.2009.07.001DOI Listing
October 2009

Hereditary colorectal cancer syndromes: familial adenomatous polyposis and lynch syndrome.

Surg Clin North Am 2008 Aug;88(4):819-44, vii

Division of General Surgery, Department of Surgery, University of Toronto, 1225-600 University Avenue, Toronto, Ontario, Canada M5G 1X5.

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http://dx.doi.org/10.1016/j.suc.2008.04.012DOI Listing
August 2008

Gastrointestinal cancers and neurofibromatosis type 1 features in children with a germline homozygous MLH1 mutation.

Gastroenterology 2004 Feb;126(2):576-85

Familial Gastrointestinal Cancer Registry and Centre for Cancer Genetics and Department of Surgery, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, ON, Canada.

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http://dx.doi.org/10.1053/j.gastro.2003.11.008DOI Listing
February 2004

The experience of loss and anticipation of distress in colorectal cancer patients undergoing genetic testing.

J Psychosom Res 2003 Nov;55(5):427-35

Familial Gastrointestinal Cancer Registry, Mount Sinai Hospital, 600 University Avenue, M5G 1X5 Toronto, ON, Canada.

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http://dx.doi.org/10.1016/s0022-3999(03)00511-7DOI Listing
November 2003

Hereditary nonpolyposis colorectal cancer--molecular basis.

Surgery 2003 Jul;134(1):29-33

Department of Surgery, Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1067/msy.2003.176DOI Listing
July 2003

Heterozygosity for the BLM(Ash) mutation and cancer risk.

Cancer Res 2003 Apr;63(8):1769-71

Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.

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April 2003

A population-based study of the extent of surgical resection of potentially curable colon cancer.

Ann Surg Oncol 2002 May;9(4):380-7

Department of Surgical Oncology, Princess Margaret Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1007/bf02573873DOI Listing
May 2002