Publications by authors named "Melkam Kebede"

21Publications

Structural and functional polarisation of human pancreatic beta cells in islets from organ donors with and without type 2 diabetes.

Diabetologia 2021 Mar 5;64(3):618-629. Epub 2021 Jan 5.

Charles Perkins Centre, Discipline of Physiology, School of Medical Sciences, University of Sydney, Camperdown, NSW, Australia.

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March 2021

Enhanced structure and function of human pluripotent stem cell-derived beta-cells cultured on extracellular matrix.

Stem Cells Transl Med 2021 Mar 4;10(3):492-505. Epub 2020 Nov 4.

Charles Perkins Centre, Discipline of Physiology, School of Medical Sciences, University of Sydney, Camperdown, New South Wales, Australia.

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March 2021

Arp2/3 nucleates F-actin coating of fusing insulin granules in pancreatic β cells to control insulin secretion.

J Cell Sci 2020 03 30;133(6). Epub 2020 Mar 30.

Discipline of Physiology, School of Medical Sciences, Charles Perkins Centre, University of Sydney, Camperdown 2006, Australia

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March 2020

Type 2 diabetes-associated single nucleotide polymorphism in Sorcs1 gene results in alternative processing of the Sorcs1 protein in INS1 β-cells.

Sci Rep 2019 12 19;9(1):19466. Epub 2019 Dec 19.

Charles Perkins Centre, School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, New South Wales, Australia.

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December 2019

ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation.

Mol Metab 2019 07 6;25:83-94. Epub 2019 May 6.

Charles Perkins Centre, School of Life and Environmental Sciences, University of Sydney, Sydney, NSW, 2006, Australia; Sydney Medical School, University of Sydney, Sydney, NSW, 2006, Australia. Electronic address:

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July 2019

Dual-Reporter β-Cell-Specific Male Transgenic Rats for the Analysis of β-Cell Functional Mass and Enrichment by Flow Cytometry.

Endocrinology 2016 Mar 15;157(3):1299-306. Epub 2015 Dec 15.

Montreal Diabetes Research Center (J.G., G.F., C.T., M.A.K., V.P.), Centre de Recherche du Centre Hospitalier de l'Université de Montréal (J.G., G.F., C.T., M.A.K., V.P.), and Departments of Medicine (V.P.) and Biochemistry (V.P.), University of Montreal, Montréal, Québec, Canada H2X 0A9.

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March 2016

Insights into obesity and diabetes at the intersection of mouse and human genetics.

Trends Endocrinol Metab 2014 Oct 15;25(10):493-501. Epub 2014 Jul 15.

Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address:

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October 2014

Glucose activates free fatty acid receptor 1 gene transcription via phosphatidylinositol-3-kinase-dependent O-GlcNAcylation of pancreas-duodenum homeobox-1.

Proc Natl Acad Sci U S A 2012 Feb 30;109(7):2376-81. Epub 2012 Jan 30.

Montreal Diabetes Research Center, Centre de Recherche du Centre Hospitalier de l'Universite de Montreal, and Department of Medicine, University of Montreal, Montreal, QC, Canada H3T 1J4.

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February 2012

The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding.

Diabetes 2008 Sep 16;57(9):2432-7. Epub 2008 Jun 16.

Montréal Diabetes Research Center, Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, Canada

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September 2008

Expression of human fructose-1,6-bisphosphatase in the liver of transgenic mice results in increased glycerol gluconeogenesis.

Endocrinology 2006 Jun 23;147(6):2764-72. Epub 2006 Feb 23.

Department of Medicine (Austin Health and Northern Health), University of Melbourne, Heidelberg Repatriation Hospital, Heidelberg Heights, Victoria 3081, Australia.

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June 2006