Melita Irving

Melita Irving

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Melita Irving

Publications by authors named "Melita Irving"

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miR-155 Overexpression in OT-1 CD8 T Cells Improves Anti-Tumor Activity against Low-Affinity Tumor Antigen.

Mol Ther Oncolytics 2020 Mar 25;16:111-123. Epub 2019 Dec 25.

Department of Fundamental Oncology and Ludwig Cancer Center, Faculty of Biology and Medicine, University of Lausanne, 1066 Epalinges, Switzerland.

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http://dx.doi.org/10.1016/j.omto.2019.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994712PMC
March 2020

Phenotypic presentations of Hajdu-Cheney syndrome according to age - 5 distinct clinical presentations.

Eur J Med Genet 2020 Feb 11;63(2):103650. Epub 2019 Apr 11.

Department of Clinical Genetics, Aarhus University Hospital, Denmark; Pediatrics and Adolescent Medicine, Centre for Rare Diseases, Aarhus University Hospital, Denmark.

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https://linkinghub.elsevier.com/retrieve/pii/S17697212183082
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http://dx.doi.org/10.1016/j.ejmg.2019.04.007DOI Listing
February 2020

Preclinical Evaluation and Dosimetry of [In]CHX-DTPA-scFv78-Fc Targeting Endosialin/Tumor Endothelial Marker 1 (TEM1).

Mol Imaging Biol 2020 Jan 28. Epub 2020 Jan 28.

Department of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1007/s11307-020-01479-8DOI Listing
January 2020

CD8 Binding of MHC-Peptide Complexes in cis or trans Regulates CD8 T-cell Responses.

J Mol Biol 2019 Dec 5;431(24):4941-4958. Epub 2019 Nov 5.

Ludwig Institute for Cancer Research, University of Lausanne, and Department of Oncology, University Hospital of Lausanne, 1009, Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2019.10.019DOI Listing
December 2019

Best practice guidelines regarding diagnosis and management of patients with type II collagen disorders.

Genet Med 2019 09 30;21(9):2070-2080. Epub 2019 Jan 30.

Department of Orthopedics and Sports Medicine, Seattle Children's Hospital, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1038/s41436-019-0446-9DOI Listing
September 2019

C-Type Natriuretic Peptide Analogue Therapy in Children with Achondroplasia. Reply.

N Engl J Med 2019 09;381(13):1291-1292

BioMarin, London, United Kingdom.

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http://dx.doi.org/10.1056/NEJMc1910394DOI Listing
September 2019

Rational combinations of immunotherapy with radiotherapy in ovarian cancer.

Lancet Oncol 2019 Aug 29;20(8):e417-e433. Epub 2019 Jul 29.

Ludwig Institute for Cancer Research, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland; Department of Oncology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1016/S1470-2045(19)30401-2DOI Listing
August 2019

C-Type Natriuretic Peptide Analogue Therapy in Children with Achondroplasia.

N Engl J Med 2019 07 18;381(1):25-35. Epub 2019 Jun 18.

From Murdoch Children's Research Institute, Royal Children's Hospital, University of Melbourne, Parkville, VIC, Australia (R.S.); Guy's and St. Thomas' NHS Foundation Trust, Evelina Children's Hospital, London (M.I.); Baylor College of Medicine, Houston (C.A.B., B.B.); Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago (J.C.); the Medical Genetics Department, Université Paris Descartes-Sorbonne Paris Cité, INSERM Unité Mixte de Recherche 1163, Institute Imagine, Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Paris (V.C.-D., K.-H.L.Q.S.); Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance (P.D.), University of California, San Francisco, Benioff Children's Hospital Oakland, Oakland (P.H.), and BioMarin Pharmaceutical, Novato (A.C., K.J., G.S.J., K.L., M.L.C.) - all in California; Vanderbilt University Medical Center, Nashville (J.P., N.O.); BioMarin, London (A.H.L., J.D.); and Johns Hopkins University School of Medicine, Baltimore (J.H.-F.).

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http://dx.doi.org/10.1056/NEJMoa1813446DOI Listing
July 2019

Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function.

Front Immunol 2019 6;10:925. Epub 2019 Jun 6.

Department of Oncology, Ludwig Institute for Cancer Research Lausanne, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.3389/fimmu.2019.00925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562565PMC
June 2019

Safety and Tolerability of Adoptive Cell Therapy in Cancer.

Drug Saf 2019 02;42(2):315-334

Department of Oncology, Lausanne University Hospital, and Ludwig Institute for Cancer Research, University of Lausanne, 1066, Lausanne, Switzerland.

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http://link.springer.com/10.1007/s40264-018-0779-3
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http://dx.doi.org/10.1007/s40264-018-0779-3DOI Listing
February 2019

Best practice guidelines regarding prenatal evaluation and delivery of patients with skeletal dysplasia.

Am J Obstet Gynecol 2018 12 23;219(6):545-562. Epub 2018 Jul 23.

Department of Orthopedics and Sports Medicine, Seattle Children's Hospital, Seattle, WA; Department of Orthopedics and Sports Medicine, University of Washington, Seattle, WA.

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https://linkinghub.elsevier.com/retrieve/pii/S00029378183059
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http://dx.doi.org/10.1016/j.ajog.2018.07.017DOI Listing
December 2018

Correction to: CART cells are prone to Fas- and DR5-mediated cell death.

J Immunother Cancer 2018 09 25;6(1):92. Epub 2018 Sep 25.

Department of Fundamental Oncology, Translational Tumor Immunology Group, Lausanne, Switzerland.

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http://dx.doi.org/10.1186/s40425-018-0410-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154881PMC
September 2018

Consensus guidelines for the use and interpretation of angiogenesis assays.

Angiogenesis 2018 08;21(3):425-532

Angiogenesis Laboratory, Department of Medical Oncology, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10456-018-9613-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237663PMC
August 2018

CART cells are prone to Fas- and DR5-mediated cell death.

J Immunother Cancer 2018 07 13;6(1):71. Epub 2018 Jul 13.

Translational Tumor Immunology Group, Department of Fundamental Oncology, Lausanne, Switzerland.

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http://dx.doi.org/10.1186/s40425-018-0385-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045821PMC
July 2018

Bisphosphonate therapy for spinal osteoporosis in Hajdu-Cheney syndrome - new data and literature review.

Orphanet J Rare Dis 2018 04 4;13(1):47. Epub 2018 Apr 4.

Department of Clinical Genetics, Guy's and St Thomas' NHS Foundation Trust, Great Maze Pond, London, SE1 9RT, UK.

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http://dx.doi.org/10.1186/s13023-018-0795-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885380PMC
April 2018

Best practices in peri-operative management of patients with skeletal dysplasias.

Am J Med Genet A 2017 Oct 1;173(10):2584-2595. Epub 2017 Aug 1.

Department of Anesthesia, Nemour's Alfred I du Pont Hospital for Children, Wilmington, Delaware.

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http://dx.doi.org/10.1002/ajmg.a.38357DOI Listing
October 2017

Engineering Chimeric Antigen Receptor T-Cells for Racing in Solid Tumors: Don't Forget the Fuel.

Front Immunol 2017 3;8:267. Epub 2017 Apr 3.

The Ludwig Institute for Cancer Research, University of Lausanne, Epalinges, Switzerland.

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http://dx.doi.org/10.3389/fimmu.2017.00267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376574PMC
April 2017

The genomic landscape of balanced cytogenetic abnormalities associated with human congenital anomalies.

Authors:
Claire Redin Harrison Brand Ryan L Collins Tammy Kammin Elyse Mitchell Jennelle C Hodge Carrie Hanscom Vamsee Pillalamarri Catarina M Seabra Mary-Alice Abbott Omar A Abdul-Rahman Erika Aberg Rhett Adley Sofia L Alcaraz-Estrada Fowzan S Alkuraya Yu An Mary-Anne Anderson Caroline Antolik Kwame Anyane-Yeboa Joan F Atkin Tina Bartell Jonathan A Bernstein Elizabeth Beyer Ian Blumenthal Ernie M H F Bongers Eva H Brilstra Chester W Brown Hennie T Brüggenwirth Bert Callewaert Colby Chiang Ken Corning Helen Cox Edwin Cuppen Benjamin B Currall Tom Cushing Dezso David Matthew A Deardorff Annelies Dheedene Marc D'Hooghe Bert B A de Vries Dawn L Earl Heather L Ferguson Heather Fisher David R FitzPatrick Pamela Gerrol Daniela Giachino Joseph T Glessner Troy Gliem Margo Grady Brett H Graham Cristin Griffis Karen W Gripp Andrea L Gropman Andrea Hanson-Kahn David J Harris Mark A Hayden Rosamund Hill Ron Hochstenbach Jodi D Hoffman Robert J Hopkin Monika W Hubshman A Micheil Innes Mira Irons Melita Irving Jessie C Jacobsen Sandra Janssens Tamison Jewett John P Johnson Marjolijn C Jongmans Stephen G Kahler David A Koolen Jerome Korzelius Peter M Kroisel Yves Lacassie William Lawless Emmanuelle Lemyre Kathleen Leppig Alex V Levin Haibo Li Hong Li Eric C Liao Cynthia Lim Edward J Lose Diane Lucente Michael J Macera Poornima Manavalan Giorgia Mandrile Carlo L Marcelis Lauren Margolin Tamara Mason Diane Masser-Frye Michael W McClellan Cinthya J Zepeda Mendoza Björn Menten Sjors Middelkamp Liya R Mikami Emily Moe Shehla Mohammed Tarja Mononen Megan E Mortenson Graciela Moya Aggie W Nieuwint Zehra Ordulu Sandhya Parkash Susan P Pauker Shahrin Pereira Danielle Perrin Katy Phelan Raul E Piña Aguilar Pino J Poddighe Giulia Pregno Salmo Raskin Linda Reis William Rhead Debra Rita Ivo Renkens Filip Roelens Jayla Ruliera Patrick Rump Samantha L P Schilit Ranad Shaheen Rebecca Sparkes Erica Spiegel Blair Stevens Matthew R Stone Julia Tagoe Joseph V Thakuria Bregje W van Bon Jiddeke van de Kamp Ineke van Der Burgt Ton van Essen Conny M van Ravenswaaij-Arts Markus J van Roosmalen Sarah Vergult Catharina M L Volker-Touw Dorothy P Warburton Matthew J Waterman Susan Wiley Anna Wilson Maria de la Concepcion A Yerena-de Vega Roberto T Zori Brynn Levy Han G Brunner Nicole de Leeuw Wigard P Kloosterman Erik C Thorland Cynthia C Morton James F Gusella Michael E Talkowski

Nat Genet 2017 01 14;49(1):36-45. Epub 2016 Nov 14.

Molecular Neurogenetics Unit, Center for Human Genetic Research, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307971PMC
January 2017

Rodriguez acrofacial dysostosis is caused by apparently de novo heterozygous mutations in the SF3B4 gene.

Am J Med Genet A 2016 12 19;170(12):3133-3137. Epub 2016 Sep 19.

Division of Medical and Molecular Genetics, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1002/ajmg.a.37946DOI Listing
December 2016

Recurrent missense mutation of () causes proximal symphalangism in a British family.

World J Orthop 2016 Dec 18;7(12):839-842. Epub 2016 Dec 18.

Andreas Leonidou, Marcos Katchburian, Department of Trauma and Orthopaedic Surgery, Maidstone and Tunbridge Wells NHS Trust, Tunbridge Wells TN2 4QJ, United Kingdom.

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http://dx.doi.org/10.5312/wjo.v7.i12.839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155261PMC
December 2016

1,2,3-Triazoles as inhibitors of indoleamine 2,3-dioxygenase 2 (IDO2).

Bioorg Med Chem Lett 2016 09 16;26(17):4330-3. Epub 2016 Jul 16.

Molecular Modeling Group, SIB Swiss Institute for Bioinformatics, CH-1015 Lausanne, Switzerland; Ludwig Center for Cancer Research of the University of Lausanne, CH-1066 Epalinges, Switzerland; Department of Oncology, University of Lausanne and Centre Hospitalier Universitaire Vaudois (CHUV), CH-1011 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.07.031DOI Listing
September 2016

Microduplications at the pseudoautosomal SHOX locus in autism spectrum disorders and related neurodevelopmental conditions.

J Med Genet 2016 08 12;53(8):536-47. Epub 2016 Apr 12.

Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK Adult Autism Spectrum and ADHD Services, Behavioural and Developmental Psychiatry, Clinical Academic Group, King's Health Partners, London, UK National Institute for Health Research (NIHR) Biomedical Research Centre for Mental Health at South London and Maudsley NHS Foundation Trust and Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.

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http://dx.doi.org/10.1136/jmedgenet-2015-103621DOI Listing
August 2016

End-Stage Renal Disease in an Infant With Hajdu-Cheney Syndrome.

Ther Apher Dial 2016 Jun;20(3):318-21

Department of Pediatric Nephrology, University Medical Centre Ljubljana, Ljubljana, Slovenia.

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http://dx.doi.org/10.1111/1744-9987.12444DOI Listing
June 2016

Targeting the tumor vasculature to enhance T cell activity.

Curr Opin Immunol 2015 Apr 6;33:55-63. Epub 2015 Feb 6.

Ludwig Center for Cancer Research of the University of Lausanne, CH-1066 Epalinges, Switzerland; Department of Oncology, University Hospital of Lausanne (CHUV), CH-1015 Lausanne, Switzerland; Ovarian Cancer Research Center, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2015.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896929PMC
April 2015

T cells bearing a chimeric antigen receptor against prostate-specific membrane antigen mediate vascular disruption and result in tumor regression.

Cancer Immunol Res 2015 Jan 30;3(1):68-84. Epub 2014 Oct 30.

Ovarian Cancer Research Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Ludwig Center for Cancer Research at the University of Lausanne, Epalinges, Switzerland. Department of Oncology, University Hospital of Lausanne (CHUV), Lausanne, Switzerland.

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http://dx.doi.org/10.1158/2326-6066.CIR-14-0192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289112PMC
January 2015

Clinical utility gene card for: 3-M syndrome - update 2013.

Eur J Hum Genet 2014 Apr 31;22(4). Epub 2013 Jul 31.

Département de Génétique, Université Paris Descartes, INSERM U781, Hôpital Necker Enfants Malades, Paris, France.

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http://dx.doi.org/10.1038/ejhg.2013.156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953895PMC
April 2014

De novo mutations in MLL cause Wiedemann-Steiner syndrome.

Am J Hum Genet 2012 Aug 12;91(2):358-64. Epub 2012 Jul 12.

South West Thames Regional Genetics Service, St George's Hospital, University of London, London SW17 0RE, UK.

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http://dx.doi.org/10.1016/j.ajhg.2012.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415539PMC
August 2012

Clinical utility gene card for: 3M syndrome.

Eur J Hum Genet 2011 Sep 2;19(9). Epub 2011 Mar 2.

Service de Génétique Clinique, Hôpital Jeanne de Flandre, CHRU, Lille, France.

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http://dx.doi.org/10.1038/ejhg.2011.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179355PMC
September 2011

Two novel COL2A1 mutations associated with a Legg-Calvé-Perthes disease-like presentation.

Clin Orthop Relat Res 2011 Jun 26;469(6):1785-90. Epub 2011 Mar 26.

Division of Clinical and Metabolic Genetics, Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1007/s11999-011-1850-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094608PMC
June 2011

Infantile onset myofibrillar myopathy due to recessive CRYAB mutations.

Neuromuscul Disord 2011 Jan 3;21(1):37-40. Epub 2010 Dec 3.

Department of Paediatric Neurology, Neuromuscular Service, Evelina Children's Hospital, London, UK.

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http://dx.doi.org/10.1016/j.nmd.2010.11.003DOI Listing
January 2011

Chondrodysplasia punctata: a clinical diagnostic and radiological review.

Clin Dysmorphol 2008 Oct;17(4):229-41

Department of Clinical Genetics, Guy's and St Thomas' Hospitals Foundation Trust, London, UK.

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http://dx.doi.org/10.1097/MCD.0b013e3282fdcc70DOI Listing
October 2008

IFT80, which encodes a conserved intraflagellar transport protein, is mutated in Jeune asphyxiating thoracic dystrophy.

Nat Genet 2007 Jun 29;39(6):727-9. Epub 2007 Apr 29.

Molecular Medicine Unit, University College London (UCL) Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK.

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http://dx.doi.org/10.1038/ng2038DOI Listing
June 2007

Neonatal teeth in X-linked Opitz (G/BBB) syndrome.

Clin Dysmorphol 2006 Jul;15(3):185-6

Department of Clinical Genetics, Guy's Hospital, London, UK.

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http://dx.doi.org/10.1097/01.mcd.0000198931.09330.e8DOI Listing
July 2006

Breast cancer genetics: unsolved questions and open perspectives in an expanding clinical practice.

Am J Med Genet C Semin Med Genet 2004 Aug;129C(1):56-64

Department of Clinical Development Sciences, St. George's Hospital Medical School, Cranmer Terrace, London SW19 0RE, UK.

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http://dx.doi.org/10.1002/ajmg.c.30019DOI Listing
August 2004

Deletion of the distal long arm of chromosome 10; is there a characteristic phenotype? A report of 15 de novo and familial cases.

Am J Med Genet A 2003 Dec;123A(2):153-63

Department of Clinical Genetics, 7th Floor, New Guy's House, Guy's Hospital, St. Thomas Street, London SE1 9RT, United Kingdom.

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http://dx.doi.org/10.1002/ajmg.a.20220DOI Listing
December 2003