Melita A Gordon

Medical Research Council Human Immunology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, OX3 9DS Oxford, United Kingdom.

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August 2020

Intestinal Perforations Associated With a High Mortality and Frequent Complications During an Epidemic of Multidrug-resistant Typhoid Fever in Blantyre, Malawi.

Authors:

Franziska Olgemoeller Jonathan J Waluza Dalitso Zeka Jillian S Gauld Peter J Diggle Jonathan M Read Thomas Edwards Chisomo L Msefula Angeziwa Chirambo Melita A Gordon Emma Thomson Robert S Heyderman Eric Borgstein Nicholas A Feasey

Clin Infect Dis 2020 Jul;71(Supplement_2):S96-S101

Malawi Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi.

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July 2020

Early Insights From Clinical Trials of Typhoid Conjugate Vaccine.

Authors:

Kathleen M Neuzil Buddha Basnyat John D Clemens Melita A Gordon Priyanka D Patel Andrew J Pollard Mila Shakya Firdausi Qadri

Clin Infect Dis 2020 Jul;71(Supplement_2):S155-S159

Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.

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July 2020

Evaluation of a standardised Vi poly-l-lysine ELISA for serology of Vi capsular polysaccharide antibodies.

Biologicals 2020 Jul 20;66:21-29. Epub 2020 Jun 20.

Division of Bacteriology, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire, EN6 3QG, UK. Electronic address:

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July 2020

Distinct climate influences on the risk of typhoid compared to invasive non-typhoid Salmonella disease in Blantyre, Malawi.

Authors:

Deus Thindwa Michael G Chipeta Marc Y R Henrion Melita A Gordon

Sci Rep 2019 12 30;9(1):20310. Epub 2019 Dec 30.

Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi.

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December 2019

The fitness landscape of the African Salmonella Typhimurium ST313 strain D23580 reveals unique properties of the pBT1 plasmid.

Authors:

Rocío Canals Roy R Chaudhuri Rebecca E Steiner Siân V Owen Natalia Quinones-Olvera Melita A Gordon Michael Baym Michael Ibba Jay C D Hinton

PLoS Pathog 2019 09 27;15(9):e1007948. Epub 2019 Sep 27.

Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom.

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September 2019

On the Ground in Malawi-First Typhoid Conjugate Vaccine Study in Africa.

Authors:

Pratiksha Patel Priyanka Patel James E Meiring Theresa Misiri Felistas Mwakiseghile Melita A Gordon

Am J Trop Med Hyg 2019 06;100(6):1299-1300

Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom.

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June 2019

Domestic River Water Use and Risk of Typhoid Fever: Results From a Case-control Study in Blantyre, Malawi.

Authors:

Jillian S Gauld Franziska Olgemoeller Rose Nkhata Chao Li Angeziwa Chirambo Tracy Morse Melita A Gordon Jonathan M Read Robert S Heyderman Neil Kennedy Peter J Diggle Nicholas A Feasey

Clin Infect Dis 2020 03;70(7):1278-1284

Department of Clinical Sciences, Liverpool School of Tropical Medicine, United Kingdom.

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March 2020

Publisher Correction: Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.

Nat Immunol 2019 Apr;20(4):514

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

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April 2019

Community Engagement Before Initiation of Typhoid Conjugate Vaccine Trial in Schools in Two Urban Townships in Blantyre, Malawi: Experience and Lessons.

Authors:

James E Meiring Rodrick Sambakunsi Elvis Moyo Theresa Misiri Felistas Mwakiseghile Pratiksha Patel Priyanka Patel John Ndaferankhande Matthew Laurens Kate Gooding Melita A Gordon

Clin Infect Dis 2019 03;68(Suppl 2):S146-S153

Malawi-Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi.

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March 2019

Typhoid Vaccine Acceleration Consortium Malawi: A Phase III, Randomized, Double-blind, Controlled Trial of the Clinical Efficacy of Typhoid Conjugate Vaccine Among Children in Blantyre, Malawi.

Authors:

James E Meiring Matthew B Laurens Pratiksha Patel Priyanka Patel Theresa Misiri Kenneth Simiyu Felistas Mwakiseghile J Kathleen Tracy Clemens Masesa Yuanyuan Liang Marc Henrion Elizabeth Rotrosen Markus Gmeiner Robert Heyderman Karen Kotloff Melita A Gordon Kathleen M Neuzil

Clin Infect Dis 2019 03;68(Suppl 2):S50-S58

Center for Vaccine Development and Global Health at the University of Maryland School of Medicine, Baltimore, MD.

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March 2019

Adding function to the genome of African Salmonella Typhimurium ST313 strain D23580.

Authors:

Rocío Canals Disa L Hammarlöf Carsten Kröger Siân V Owen Wai Yee Fong Lizeth Lacharme-Lora Xiaojun Zhu Nicolas Wenner Sarah E Carden Jared Honeycutt Denise M Monack Robert A Kingsley Philip Brownridge Roy R Chaudhuri Will P M Rowe Alexander V Predeus Karsten Hokamp Melita A Gordon Jay C D Hinton

PLoS Biol 2019 01 15;17(1):e3000059. Epub 2019 Jan 15.

Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom.

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January 2019

Invasive Salmonella exploits divergent immune evasion strategies in infected and bystander dendritic cell subsets.

Authors:

Anna Aulicino Kevin C Rue-Albrecht Lorena Preciado-Llanes Giorgio Napolitani Neil Ashley Adam Cribbs Jana Koth B Christoffer Lagerholm Tim Ambrose Melita A Gordon David Sims Alison Simmons

Nat Commun 2018 11 19;9(1):4883. Epub 2018 Nov 19.

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, UK.

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November 2018

Five-year single-centre experience of carcinoma of the oesophagus from Blantyre, Malawi.

Authors:

John David Chetwood Peter J Finch Anstead Kankwatira Jane Mallewa Melita A Gordon Leo Masamba

BMJ Open Gastroenterol 2018 15;5(1):e000232. Epub 2018 Oct 15.

Department of Medicine, Queen Elizabeth Central Hospital, Blantyre, Malawi.

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October 2018

Epidemiology of hepatitis B, C and D in Malawi: systematic review.

Authors:

Alexander J Stockdale Collins Mitambo Dean Everett Anna Maria Geretti Melita A Gordon

BMC Infect Dis 2018 Oct 12;18(1):516. Epub 2018 Oct 12.

Malawi Liverpool Wellcome Trust Clinical Research Programme, Chichiri 3, PO Box 30096, Blantyre, Malawi.

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October 2018

The Impact of Vaccination and Prior Exposure on Stool Shedding of Salmonella Typhi and Salmonella Paratyphi in 6 Controlled Human Infection Studies.

Authors:

Malick M Gibani Merryn Voysey Celina Jin Claire Jones Helena Thomaides-Brears Elizabeth Jones Philip Baker Marcus Morgan Alison Simmons Melita A Gordon Vincenzo Cerundolo Virginia E Pitzer Brian Angus Myron M Levine Thomas C Darton Andrew J Pollard

Clin Infect Dis 2019 04;68(8):1265-1273

Oxford Vaccine Group, Department of Paediatrics, University of Oxford.

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April 2019

Evaluating the safety, tolerability, pharmacokinetics and efficacy of clofazimine in cryptosporidiosis (CRYPTOFAZ): study protocol for a randomized controlled trial.

Authors:

Patrick Nachipo David Hermann Gerald Quinnan Melita A Gordon Wesley C Van Voorhis Pui-Ying Iroh Tam

Trials 2018 Aug 23;19(1):456. Epub 2018 Aug 23.

University of Malawi College of Medicine, Blantyre, Malawi.

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August 2018

Typhoid conjugate vaccines: making vaccine history in Africa.

Authors:

James E Meiring Pratiksha Patel Priyanka Patel Melita A Gordon

Expert Rev Vaccines 2018 08 23;17(8):673-676. Epub 2018 Jul 23.

b Malawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine , Blantyre , Malawi.

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August 2018

Longevity of duodenal and peripheral T-cell and humoral responses to live-attenuated Salmonella Typhi strain Ty21a.

Authors:

Shaun H Pennington Daniela M Ferreira Jesús Reiné Tonney S Nyirenda Ameeka L Thompson Carole A Hancock Angela D Wright Stephen B Gordon Melita A Gordon

Vaccine 2018 07 27;36(31):4725-4733. Epub 2018 Jun 27.

Department of Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health, University of Liverpool, UK; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, College of Medicine, Queen Elizabeth Central Hospital, Malawi. Electronic address:

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July 2018

Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.

Nat Immunol 2018 07 20;19(7):742-754. Epub 2018 Jun 20.

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

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July 2018

Role of a single noncoding nucleotide in the evolution of an epidemic African clade of .

Authors:

Disa L Hammarlöf Carsten Kröger Siân V Owen Rocío Canals Lizeth Lacharme-Lora Nicolas Wenner Anna E Schager Timothy J Wells Ian R Henderson Paul Wigley Karsten Hokamp Nicholas A Feasey Melita A Gordon Jay C D Hinton

Proc Natl Acad Sci U S A 2018 03 27;115(11):E2614-E2623. Epub 2018 Feb 27.

Institute of Integrative Biology, University of Liverpool, L69 7ZB Liverpool, United Kingdom;

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March 2018

Immunological bases of increased susceptibility to invasive nontyphoidal Salmonella infection in children with malaria and anaemia.

Authors:

Tonney S Nyirenda Wilson L Mandala Melita A Gordon Pietro Mastroeni

Microbes Infect 2018 Oct - Nov;20(9-10):589-598. Epub 2017 Dec 15.

Department of Veterinary Medicine, University of Cambridge, United Kingdom.

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September 2019

Trends in antimicrobial resistance in bloodstream infection isolates at a large urban hospital in Malawi (1998-2016): a surveillance study.

Authors:

Patrick Musicha Jennifer E Cornick Naor Bar-Zeev Neil French Clemens Masesa Brigitte Denis Neil Kennedy Jane Mallewa Melita A Gordon Chisomo L Msefula Robert S Heyderman Dean B Everett Nicholas A Feasey

Lancet Infect Dis 2017 10 14;17(10):1042-1052. Epub 2017 Aug 14.

Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi; Liverpool School of Tropical Medicine, Liverpool, UK. Electronic address:

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October 2017