Melike Pekmezci

Melike Pekmezci

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Melike Pekmezci

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Loss of H3K27 trimethylation by immunohistochemistry is frequent in oligodendroglioma, IDH-mutant and 1p/19q-codeleted, but is neither a sensitive nor a specific marker.

Acta Neuropathol 2020 Mar 7;139(3):597-600. Epub 2020 Jan 7.

Department of Pathology, University of California, San Francisco (UCSF), 505 Parnassus Ave, Room M551, San Francisco, CA, 94143, USA.

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http://dx.doi.org/10.1007/s00401-019-02123-8DOI Listing
March 2020

Next-Generation Sequencing of Retinoblastoma Identifies Pathogenic Alterations beyond RB1 Inactivation That Correlate with Aggressive Histopathologic Features.

Ophthalmology 2019 Dec 12. Epub 2019 Dec 12.

Department of Ophthalmology, University of California, San Francisco, San Francisco, California; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1016/j.ophtha.2019.12.005DOI Listing
December 2019

Intracapsular High-Grade Ductal Carcinoma In-Situ Ex Pleomorphic Adenoma of the Lacrimal Gland.

Ophthalmic Plast Reconstr Surg 2020 Jan/Feb;36(1):e1-e3

Department of Ophthalmology, University of California, San Francisco.

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http://dx.doi.org/10.1097/IOP.0000000000001491DOI Listing
November 2019

Molecular features and clinical outcomes in surgically treated low-grade diffuse gliomas in patients over the age of 60.

J Neurooncol 2019 Jan 29;141(2):383-391. Epub 2018 Nov 29.

Department of Neurological Surgery, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1007/s11060-018-03044-4DOI Listing
January 2019

Choroidal Lymphoma Discovered on Ultrasound in a Patient with Suspected Corneal Tumor.

Ocul Oncol Pathol 2018 Sep 14;4(5):318-321. Epub 2018 Feb 14.

Department of Ophthalmology, University of California, San Francisco, California, USA.

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https://www.karger.com/Article/FullText/486039
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http://dx.doi.org/10.1159/000486039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167682PMC
September 2018

Aberrant ATRX protein expression is associated with poor overall survival in NF1-MPNST.

Oncotarget 2018 May 1;9(33):23018-23028. Epub 2018 May 1.

Division of Neuropathology, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.

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http://www.oncotarget.com/fulltext/25195
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http://dx.doi.org/10.18632/oncotarget.25195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955415PMC
May 2018

Comprehensive Molecular Profiling Identifies FOXM1 as a Key Transcription Factor for Meningioma Proliferation.

Cell Rep 2018 03;22(13):3672-3683

Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, USA; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.03.013DOI Listing
March 2018

Significance of H3K27me3 loss in the diagnosis of malignant peripheral nerve sheath tumors.

Mod Pathol 2017 12 4;30(12):1710-1719. Epub 2017 Aug 4.

Department of Pathology, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1038/modpathol.2017.97DOI Listing
December 2017

Utility of Pit-1 Immunostaining in Distinguishing Pituitary Adenomas of Primitive Differentiation from Null Cell Adenomas.

Endocr Pathol 2017 Dec;28(4):287-292

Division of Neuropathology, Department of Pathology, University of California, 505 Parnassus Ave, Room M-551, Box 0102, San Francisco, CA, 94143, USA.

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http://dx.doi.org/10.1007/s12022-017-9503-6DOI Listing
December 2017

Apparent diffusion coefficient and pituitary macroadenomas: pre-operative assessment of tumor atypia.

Pituitary 2017 Apr;20(2):195-200

Department of Radiology, University of California San Francisco, 505 Parnassus Avenue, M-391, San Francisco, CA, 94143-0628, USA.

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http://dx.doi.org/10.1007/s11102-016-0759-5DOI Listing
April 2017

Comparision of New Diagnostic Tools for Malignant Peripheral Nerve Sheath Tumors.

Pathol Oncol Res 2017 04 12;23(2):393-398. Epub 2016 Oct 12.

Division of Neuropathology, Department of Pathology, University of California San Francisco, San Francisco, CA, 94143, USA.

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http://dx.doi.org/10.1007/s12253-016-0125-yDOI Listing
April 2017

Erratum to: Surgical resection of fourth ventricular ependymomas: case series and technical nuances.

J Neurooncol 2017 01;131(2):423

Department of Neurological Surgery, University of California San Francisco, 505 Parnassus Avenue, M-779, San Francisco, CA, 94143-0112, USA.

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http://dx.doi.org/10.1007/s11060-016-2343-2DOI Listing
January 2017

Surgical resection of fourth ventricular ependymomas: case series and technical nuances.

J Neurooncol 2016 11 24;130(2):341-349. Epub 2016 Oct 24.

Department of Neurological Surgery, University of California San Francisco, 505 Parnassus Avenue, M-779, San Francisco, CA, 94143-0112, USA.

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http://dx.doi.org/10.1007/s11060-016-2198-6DOI Listing
November 2016

SOX10 Distinguishes Pilocytic and Pilomyxoid Astrocytomas From Ependymomas but Shows No Differences in Expression Level in Ependymomas From Infants Versus Older Children or Among Molecular Subgroups.

J Neuropathol Exp Neurol 2016 Apr 4;75(4):295-8. Epub 2016 Mar 4.

From the Department of Pathology (BKKD, AMR); Department of Neurology (BKKD); and Department of Neurosurgery, University of Colorado Health Sciences Center (BKKD), Aurora, Colorado; Department of Neuro-Oncology, Children's Hospital Colorado (AMD, NKF), Aurora, Colorado; and Department of Pathology, University of California San Francisco (MP, TT), San Francisco, California.

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http://dx.doi.org/10.1093/jnen/nlw010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009481PMC
April 2016

Spinal Myxopapillary Ependymomas Demonstrate a Warburg Phenotype.

Clin Cancer Res 2015 Aug 8;21(16):3750-8. Epub 2015 May 8.

Developmental & Stem Cell Biology Program, Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada. Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537825PMC
August 2015

Simultaneous serum aquaporin-4 antibody and CSF NMDA receptor antibody-positive encephalitis.

Neurol Neuroimmunol Neuroinflamm 2015 Jun 9;2(3):e101. Epub 2015 Apr 9.

Departments of Neurology (J.P.O., B.A.C.C.) and Pathology (M.P.), University of California, San Francisco.

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http://dx.doi.org/10.1212/NXI.0000000000000101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396527PMC
June 2015

Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors.

N Engl J Med 2015 Jun 10;372(26):2499-508. Epub 2015 Jun 10.

From the Departments of Health Sciences Research (J.E.E.-P., P.A.D., H.S., M.L.K.), Laboratory Medicine and Pathology (D.H.L., G.S., A.A.C., T.M.K., C.E.P., A.R.C., C.H., C.G., R.B.J.), Neurology (D.H.L., B.P.O.), and Oncology (J.C.B.), Mayo Clinic, Rochester, MN; the Departments of Neurological Surgery (A.M.M., K.M.W., T.R., I.V.S., H.M.H., L.S.M., S.Z., A.P., M.S.B., S.M.C., M.D.P., J.K.W., M.R.W.), Epidemiology and Biostatistics (A.M.M., P.M.B., J.W., J.K.W., M.R.W.) and Pathology (M.P., R.M., G.F.R., A.P., T.T.) and the Institute of Human Genetics (J.W., J.K.W., M.R.W.), University of California, San Francisco, and the Bioinformatics Core, Gladstone Institutes (A.R.P.) - all in San Francisco; and the Department of Pathology and Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York (J.T.H.).

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http://www.nejm.org/doi/10.1056/NEJMoa1407279
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http://dx.doi.org/10.1056/NEJMoa1407279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489704PMC
June 2015

CDKN2A loss is associated with shortened overall survival in lower-grade (World Health Organization Grades II-III) astrocytomas.

J Neuropathol Exp Neurol 2015 May;74(5):442-52

From the Departments of Neurology, Pediatrics, and Neurosurgery, Stanford University School of Medicine, Stanford (HV); Department of Anatomic Pathology, University of California San Francisco Medical School (GFR, MP, AP); Division of Neuroepidemiology (HMH, TR, JKW, MRW, KMW), Departments of Neurological Surgery (REM, AMM, JJP, AP) and Epidemiology and Biostatistics (AMM); and Institute for Human Genetics, University of California San Francisco (JKW, MRW, KMW), San Francisco, California.

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http://pdfs.journals.lww.com/jneuropath/2015/05000/CDKN2A_Lo
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http://jnen.oxfordjournals.org/cgi/doi/10.1097/NEN.000000000
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http://dx.doi.org/10.1097/NEN.0000000000000188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397174PMC
May 2015

Response to "the epidemiology of glioma in adults: a 'state of the science' review".

Neuro Oncol 2015 Apr;17(4):624-6

Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio (Q.T.O., J.B.S.); Centre Hospitalo-Universitaire Montpellier and Institut National de la Sante et de la Recherche Medicale, Montpellier, France (L.B.); School of Public Heath, University of Alberta, Edmonton, Canada (F.G.D); International Agency for Research on Cancer, Lyon, France (I.D.); The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio (J.L.F.); Centre for Research in Environmental Epidemiology, Barcelona, Spain (C.E.L, M.C.T.); Universitat Pompeu Fabra, Barcelona, Spain (C.E.L., M.C.T.); C.I.B.E.R Epidemiología y Salud Pública, Barcelona, Spain (C.E.L., M.C.T.); Department of Pathology, University of California, San Francisco School of Medicine, San Francisco, California (M.P.); Department of Epidemiology, College of Public Health, The Ohio State University, Columbus, Ohio (J.A.S); McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Canada (M.C.T); Department of Neurological Surgery, University of California, San Francisco School of Medicine, San Francisco, California (K.M.W., M.R.W.).

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http://dx.doi.org/10.1093/neuonc/nov022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483084PMC
April 2015

Practical molecular pathologic diagnosis of infiltrating gliomas.

Surg Pathol Clin 2015 Mar 4;8(1):49-61. Epub 2014 Dec 4.

Division of Neuropathology, Department of Pathology, University of California, San Francisco, 505 Parnassus Avenue, #M551, Box 0102, San Francisco, CA 94143, USA; Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.path.2014.10.004DOI Listing
March 2015

Optic nerve diffusion tensor imaging parameters and their correlation with optic disc topography and disease severity in adult glaucoma patients and controls.

J Glaucoma 2014 Oct-Nov;23(8):513-20

Departments of *Ophthalmology and Visual Sciences †Neurology §Biostatistics ¶Radiology, Washington University School of Medicine, St Louis, MO ‡Department of Radiology, Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN ∥Department of Ophthalmology, University of California, San Francisco, CA.

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http://pdfs.journals.lww.com/glaucomajournal/2014/10000/Opti
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/IJG.0b013e318294861dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800509PMC
February 2015

Morphologic and immunohistochemical features of malignant peripheral nerve sheath tumors and cellular schwannomas.

Mod Pathol 2015 Feb 5;28(2):187-200. Epub 2014 Sep 5.

1] Division of Neuropathology, Department of Pathology, University of California San Francisco, San Francisco, CA, USA [2] Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.

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http://www.nature.com/articles/modpathol2014109
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http://dx.doi.org/10.1038/modpathol.2014.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816504PMC
February 2015

Low-grade small round cell tumor of the cauda equina with EWSR1-WT1 fusion and indolent clinical course.

Hum Pathol 2015 Jan 18;46(1):153-8. Epub 2014 Oct 18.

Department of Pathology, University of California San Francisco (UCSF), San Francisco, CA, 94143; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, 94143.

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http://dx.doi.org/10.1016/j.humpath.2014.09.015DOI Listing
January 2015

Successful treatment of a very rare angiosarcoma involving the lumbar spine via en-bloc resection and radiotherapy: case report.

Turk Neurosurg 2014 ;24(1):140-5

University of California San Francisco (UCSF), Department of Neurological Surgery, San Francisco, California, USA.

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http://dx.doi.org/10.5137/1019-5149.JTN.8134-13.0DOI Listing
October 2014

Genetic markers in adult high-grade gliomas.

Semin Radiat Oncol 2014 Oct;24(4):235-9

Department of Pathology, University of California San Francisco, San Francisco, CA. Electronic address:

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http://dx.doi.org/10.1016/j.semradonc.2014.06.005DOI Listing
October 2014

Risk factors for glaucoma suspicion in healthy young asian and caucasian americans.

J Ophthalmol 2014 21;2014:726760. Epub 2014 Jul 21.

Department of Ophthalmology, University of California, 10 Koret Way, San Francisco, CA 94143-0730, USA.

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http://dx.doi.org/10.1155/2014/726760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130190PMC
August 2014

Adult-Onset Fatal Neurohepatopathy in a Woman Caused by MPV17 Mutation.

JIMD Rep 2014 5;13:37-41. Epub 2013 Nov 5.

Division of Medical Genetics, Department of Pediatrics, UCSF Benioff Children's Hospital, San Francisco, CA, USA,

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http://dx.doi.org/10.1007/8904_2013_267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110326PMC
July 2014

BRAFV600E mutation in sporadic and neurofibromatosis type 1-related malignant peripheral nerve sheath tumors.

Neuro Oncol 2014 Mar 22;16(3):466-7. Epub 2013 Dec 22.

Division of Medical Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri (A.C.H., B.V.T.); Department of Pathology and Immunology, UCSF School of Medicine, San Francisco, California (M.P., A.P.); Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri (S.D.); Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri (A.J.A.); Department of Neurology, Washington University School of Medicine, St. Louis, Missouri (D.H.G.).

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https://academic.oup.com/neuro-oncology/article-lookup/doi/1
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http://dx.doi.org/10.1093/neuonc/not248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922521PMC
March 2014

Diagnostic utility of SOX10 to distinguish malignant peripheral nerve sheath tumor from synovial sarcoma, including intraneural synovial sarcoma.

Mod Pathol 2014 Jan 9;27(1):55-61. Epub 2013 Aug 9.

Department of Pathology, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1038/modpathol.2013.115DOI Listing
January 2014

Differences in vision between clinic and home and the effect of lighting in older adults with and without glaucoma.

JAMA Ophthalmol 2013 Dec;131(12):1554-62

Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri.

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http://dx.doi.org/10.1001/jamaophthalmol.2013.4995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377300PMC
December 2013

Headache and focal neurologic deficits in a 37-year-old woman.

JAMA Neurol 2013 Nov;70(11):1445-9

Department of Neurology, University of California, San Francisco.

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http://dx.doi.org/10.1001/jamaneurol.2013.3933DOI Listing
November 2013

A comprehensive long-term retrospective analysis of silent corticotrophic adenomas vs hormone-negative adenomas.

Neurosurgery 2013 Jul;73(1):8-17; discussion 17-8

Department of Neurosurgery and The California Center for Pituitary Disorders (CCPD), University of California at San Francisco (UCSF), San Francisco, California, USA.

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http://dx.doi.org/10.1227/01.neu.0000429858.96652.1eDOI Listing
July 2013

Subependymal spread of recurrent glioblastoma detected with the intraoperative use of 5-aminolevulinic acid: case report.

J Neurosurg 2013 Jun 19;118(6):1220-3. Epub 2013 Feb 19.

Department of Neurological Surgery, University of California, San Francisco, California 94143-0112, USA.

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https://thejns.org/view/journals/j-neurosurg/118/6/article-p
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http://dx.doi.org/10.3171/2013.1.JNS121537DOI Listing
June 2013

Neuropathology of brain metastases.

Surg Neurol Int 2013 2;4(Suppl 4):S245-55. Epub 2013 May 2.

Department of Pathology, University of California, Division of Neuropathology, 505 Parnassus Avenue, M551, San Francisco, California, USA.

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http://surgicalneurologyint.com/surgicalint-articles/neuropa
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http://dx.doi.org/10.4103/2152-7806.111302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656562PMC
May 2013

Evaluation of biomarkers in multifocal/multicentric invasive breast carcinomas.

Int J Surg Pathol 2013 Apr 30;21(2):126-32. Epub 2012 Nov 30.

University of California San Francisco, Maywood, IL, USA.

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http://dx.doi.org/10.1177/1066896912467370DOI Listing
April 2013

Comparison of optic disc parameters measured by RTVue-100 FDOCT versus HRT-II.

J Glaucoma 2012 Oct-Nov;21(8):516-22

Department of Ophthalmology, University of California, San Francisco, CA 94143-0730, USA.

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http://dx.doi.org/10.1097/IJG.0b013e3182253e58DOI Listing
February 2013

Dark-light change of iris parameters and related factors among American Caucasians, American Chinese, and Mainland Chinese.

Curr Eye Res 2012 Jul 11;37(7):599-605. Epub 2012 May 11.

Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

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http://dx.doi.org/10.3109/02713683.2012.660593DOI Listing
July 2012

The superiority of conservative resection and adjuvant radiation for craniopharyngiomas.

J Neurooncol 2012 May 15;108(1):133-9. Epub 2012 Feb 15.

Department of Radiation Oncology, University of California, San Francisco (UCSF), San Francisco, CA 94143-1708, USA.

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http://dx.doi.org/10.1007/s11060-012-0806-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879154PMC
May 2012

Emergence of a high-grade sarcoma in a recurrent meningioma: malignant progression or collision tumor?

Arch Pathol Lab Med 2011 Jul;135(7):935-40

Department of Pathology, Istanbul University Cerrahpasa School of Medicine, Istanbul, Turkey.

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http://dx.doi.org/10.1043/2010-0414-CRR1.1DOI Listing
July 2011

Effect of measurement order between right and left eyes on intraocular pressure measurement.

Arch Ophthalmol 2011 Mar;129(3):276-81

Department of Ophthalmology, University of California, San Francisco, USA.

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http://dx.doi.org/10.1001/archophthalmol.2011.33DOI Listing
March 2011

Neural stem cells and their role in the pathology and classification of central nervous system tumors.

Turk Patoloji Derg 2011 Jan;27(1):1-11

Department of Pathology, University of California San Francisco, San Francisco, USA.

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January 2011

Intra-examiner repeatability and agreement of corneal pachymetry map measurement by time-domain and Fourier-domain optical coherence tomography.

Graefes Arch Clin Exp Ophthalmol 2010 Nov 30;248(11):1647-56. Epub 2010 Mar 30.

Department of Ophthalmology, University of California, San Francisco, Box 0730, 10 Koret Way K325, San Francisco, CA 94143-0730, USA.

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http://dx.doi.org/10.1007/s00417-010-1360-7DOI Listing
November 2010

Clinicopathological characteristics of adamantinomatous and papillary craniopharyngiomas: University of California, San Francisco experience 1985-2005.

Neurosurgery 2010 Nov;67(5):1341-9; discussion 1349

Department of Pathology, University of California, San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1227/NEU.0b013e3181f2b583DOI Listing
November 2010

Resident-performed Ahmed glaucoma valve surgery.

Ophthalmic Surg Lasers Imaging 2010 Mar-Apr;41(2):222-7

Department of Ophthalmology, University of California, San Francisco, California, USA.

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http://dx.doi.org/10.3928/15428877-20100303-11DOI Listing
June 2010

High prevalence of narrow angles among Chinese-American glaucoma and glaucoma suspect patients.

J Glaucoma 2009 Oct-Nov;18(8):578-81

Department of Ophthalmology, University of California, San Francisco, CA 94143-0730, USA.

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http://dx.doi.org/10.1097/IJG.0b013e3181996f19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836874PMC
December 2009

Anterior segment optical coherence tomography as a screening tool for the assessment of the anterior segment angle.

Ophthalmic Surg Lasers Imaging 2009 Jul-Aug;40(4):389-98

University of California, San Francisco, Department of Ophthalmology, San Francisco, CA 94143-0730, USA.

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http://dx.doi.org/10.3928/15428877-20096030-07DOI Listing
September 2009

Comparison of different modes in optical coherence tomography and ultrasound biomicroscopy in anterior chamber angle assessment.

J Glaucoma 2009 Aug;18(6):472-8

Department of Ophthalmology, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1097/IJG.0b013e31818fb41dDOI Listing
August 2009

The characteristics of glaucoma in Japanese Americans.

Arch Ophthalmol 2009 Feb;127(2):167-71

Department of Ophthalmology, University of California San Francisco, San Francisco, CA, USA.

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http://archopht.jamanetwork.com/article.aspx?doi=10.1001/arc
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http://dx.doi.org/10.1001/archophthalmol.2008.593DOI Listing
February 2009