Melanie Kucherlapati

Melanie Kucherlapati

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Melanie Kucherlapati

Melanie Kucherlapati

Publications by authors named "Melanie Kucherlapati"

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19Publications

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Optical imaging with a novel cathepsin-activatable probe for enhanced detection of colorectal cancer.

Am J Nucl Med Mol Imaging 2019 15;9(5):230-242. Epub 2019 Oct 15.

Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital Charlestown, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872479PMC
October 2019

Examining transcriptional changes to DNA replication and repair factors over uveal melanoma subtypes.

BMC Cancer 2018 Aug 14;18(1):818. Epub 2018 Aug 14.

Department of Genetics, Harvard Medical School, Boston, 02115, MA, USA.

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http://dx.doi.org/10.1186/s12885-018-4705-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092802PMC
August 2018

A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases.

Cell Rep 2018 07;24(2):515-527

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.06.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092947PMC
July 2018

A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations.

Cancer Cell 2017 06 18;31(6):820-832.e3. Epub 2017 May 18.

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502825PMC
June 2017

Mesalazine and thymoquinone attenuate intestinal tumour development in Msh2(loxP/loxP) Villin-Cre mice.

Gut 2015 Dec 26;64(12):1905-12. Epub 2014 Nov 26.

Christian Doppler Laboratory for Molecular Cancer Chemoprevention, Medical University of Vienna, Vienna, Austria Division of Gastroenterology and Hepatology, Department of Medicine 3, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1136/gutjnl-2014-307663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680183PMC
December 2015

MAPRE1 as a plasma biomarker for early-stage colorectal cancer and adenomas.

Cancer Prev Res (Phila) 2015 Nov 4;8(11):1112-9. Epub 2015 Sep 4.

Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1940-6207.CAPR-15-0077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633385PMC
November 2015

An EGFR targeted PET imaging probe for the detection of colonic adenocarcinomas in the setting of colitis.

Theranostics 2014 1;4(9):893-903. Epub 2014 Jul 1.

1. Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA;

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http://dx.doi.org/10.7150/thno.9425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107290PMC
April 2015

Aspirin and low-dose nitric oxide-donating aspirin increase life span in a Lynch syndrome mouse model.

Cancer Prev Res (Phila) 2011 May 24;4(5):684-93. Epub 2011 Mar 24.

Department of Molecular Virology, Immunology & Medical Genetics, Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-10-0319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991477PMC
May 2011

An Msh2 conditional knockout mouse for studying intestinal cancer and testing anticancer agents.

Gastroenterology 2010 Mar 18;138(3):993-1002.e1. Epub 2009 Nov 18.

Department of Medicine/Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1053/j.gastro.2009.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862591PMC
March 2010

Adenomatous polyposis coli (APC) is required for normal development of skin and thymus.

PLoS Genet 2006 Sep 28;2(9):e146. Epub 2006 Jul 28.

Harvard-Partners Center for Genetics and Genomics, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.0020146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1564426PMC
September 2006

Inactivation of conditional Rb by Villin-Cre leads to aggressive tumors outside the gastrointestinal tract.

Cancer Res 2006 Apr;66(7):3576-83

Harvard-Partners Center for Genetics and Genomics, Harvard Medical School, New Research Building 160B, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-05-2699DOI Listing
April 2006

Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression.

Proc Natl Acad Sci U S A 2002 Jul 15;99(15):9924-9. Epub 2002 Jul 15.

Department of Medicine and Harvard Partners Center for Genetics and Genomics, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.152321699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC126601PMC
July 2002