Publications by authors named "Melanie Kucherlapati"

20Publications

Modulation of proliferation factors in lung adenocarcinoma with an analysis of the transcriptional consequences of genomic EGFR activation.

Oncotarget 2019 Dec 10;10(65):6913-6933. Epub 2019 Dec 10.

Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.

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December 2019

Optical imaging with a novel cathepsin-activatable probe for enhanced detection of colorectal cancer.

Am J Nucl Med Mol Imaging 2019 15;9(5):230-242. Epub 2019 Oct 15.

Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital Charlestown, MA, USA.

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October 2019

Examining transcriptional changes to DNA replication and repair factors over uveal melanoma subtypes.

BMC Cancer 2018 Aug 14;18(1):818. Epub 2018 Aug 14.

Department of Genetics, Harvard Medical School, Boston, 02115, MA, USA.

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August 2018

A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases.

Cell Rep 2018 07;24(2):515-527

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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July 2018

A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations.

Cancer Cell 2017 06 18;31(6):820-832.e3. Epub 2017 May 18.

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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June 2017

MAPRE1 as a plasma biomarker for early-stage colorectal cancer and adenomas.

Cancer Prev Res (Phila) 2015 Nov 4;8(11):1112-9. Epub 2015 Sep 4.

Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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November 2015

Mesalazine and thymoquinone attenuate intestinal tumour development in Msh2(loxP/loxP) Villin-Cre mice.

Gut 2015 Dec 26;64(12):1905-12. Epub 2014 Nov 26.

Christian Doppler Laboratory for Molecular Cancer Chemoprevention, Medical University of Vienna, Vienna, Austria Division of Gastroenterology and Hepatology, Department of Medicine 3, Medical University of Vienna, Vienna, Austria.

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December 2015

An EGFR targeted PET imaging probe for the detection of colonic adenocarcinomas in the setting of colitis.

Theranostics 2014 1;4(9):893-903. Epub 2014 Jul 1.

1. Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA;

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April 2015

Genotype directed therapy in murine mismatch repair deficient tumors.

PLoS One 2013 23;8(7):e68817. Epub 2013 Jul 23.

Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.

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March 2014

Aspirin and low-dose nitric oxide-donating aspirin increase life span in a Lynch syndrome mouse model.

Cancer Prev Res (Phila) 2011 May 24;4(5):684-93. Epub 2011 Mar 24.

Department of Molecular Virology, Immunology & Medical Genetics, Ohio State University, Columbus, OH 43210, USA.

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May 2011

An Msh2 conditional knockout mouse for studying intestinal cancer and testing anticancer agents.

Gastroenterology 2010 Mar 18;138(3):993-1002.e1. Epub 2009 Nov 18.

Department of Medicine/Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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March 2010

Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon.

Proc Natl Acad Sci U S A 2008 Oct 1;105(40):15493-8. Epub 2008 Oct 1.

Harvard Partners Center for Genetics and Genomics, Harvard Medical School, Boston, MA 02115, USA.

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October 2008

Adenomatous polyposis coli (APC) is required for normal development of skin and thymus.

PLoS Genet 2006 Sep 28;2(9):e146. Epub 2006 Jul 28.

Harvard-Partners Center for Genetics and Genomics, Harvard Medical School, Boston, Massachusetts, United States of America.

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September 2006

Inactivation of conditional Rb by Villin-Cre leads to aggressive tumors outside the gastrointestinal tract.

Cancer Res 2006 Apr;66(7):3576-83

Harvard-Partners Center for Genetics and Genomics, Harvard Medical School, New Research Building 160B, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.

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April 2006

Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression.

Proc Natl Acad Sci U S A 2002 Jul 15;99(15):9924-9. Epub 2002 Jul 15.

Department of Medicine and Harvard Partners Center for Genetics and Genomics, Harvard Medical School, Boston, MA 02115, USA.

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July 2002