Melanie A Pritchard

Melanie A Pritchard

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Melanie A Pritchard

Melanie A Pritchard

Publications by authors named "Melanie A Pritchard"

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RCAN 1 and 3 proteins regulate thymic positive selection.

Biochem Biophys Res Commun 2015 May 14;460(2):295-301. Epub 2015 Mar 14.

Human Molecular Genetics Laboratory, Cell Signaling Unit, Bellvitge Biomedical Research Institute - IDIBELL, L'Hospitalet de Llobregat, Barcelona 08908, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.03.029DOI Listing
May 2015

RCAN1 regulates mitochondrial function and increases susceptibility to oxidative stress in mammalian cells.

Oxid Med Cell Longev 2014 9;2014:520316. Epub 2014 Jun 9.

Molecular and Cellular Neuroscience Group, Department of Human Physiology and Centre for Neuroscience, Flinders University, Adelaide, SA 5042, Australia.

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http://dx.doi.org/10.1155/2014/520316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070399PMC
February 2015

Transcriptional profiling of the postnatal brain of the Ts1Cje mouse model of Down syndrome.

Genom Data 2014 Dec 2;2:314-7. Epub 2014 Oct 2.

Walter and Eliza Hall Institute of Medical Research, Victoria, Australia ; Centre for Cancer Biology, University of South Australia, Department of Molecular Pathology, SA Pathology, Adelaide, Australia ; School of Molecular and Biomedical Bioscience, University of Adelaide, Adelaide, Australia ; School of Medicine, Faculty of Health Sciences, University of Adelaide, Adelaide, Australia.

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http://dx.doi.org/10.1016/j.gdata.2014.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535870PMC
December 2014

Role of metal ions in the cognitive decline of Down syndrome.

Front Aging Neurosci 2014 23;6:136. Epub 2014 Jun 23.

Oxidation Biology Unit, Florey Institute of Neuroscience and Mental Health Parkville, VIC, Australia.

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http://journal.frontiersin.org/article/10.3389/fnagi.2014.00
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http://dx.doi.org/10.3389/fnagi.2014.00136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066992PMC
July 2014

Upregulation of RCAN1 causes Down syndrome-like immune dysfunction.

J Med Genet 2013 Jul 3;50(7):444-54. Epub 2013 May 3.

Department Biochemistry and Molecular Biology, Monash University, Wellington Rd, Clayton, VIC 3800, Australia.

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http://dx.doi.org/10.1136/jmedgenet-2013-101522DOI Listing
July 2013

RCAN1 regulates vesicle recycling and quantal release kinetics via effects on calcineurin activity.

J Neurochem 2013 Feb;124(3):290-9

Discipline of Human Physiology and Centre for Neuroscience, Flinders University, Adelaide, South Australia, Australia.

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http://doi.wiley.com/10.1111/jnc.12086
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http://dx.doi.org/10.1111/jnc.12086DOI Listing
February 2013

Increased expression of the glucose-responsive gene, RCAN1, causes hypoinsulinemia, β-cell dysfunction, and diabetes.

Endocrinology 2012 Nov 25;153(11):5212-21. Epub 2012 Sep 25.

Flinders Medical Science and Technology and Centre for Neuroscience, Flinders University, Adelaide, Australia.

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http://dx.doi.org/10.1210/en.2011-2149DOI Listing
November 2012

Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory.

Hum Mol Genet 2012 Jul 17;21(13):3025-41. Epub 2012 Apr 17.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, 3168 Victoria, Australia.

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http://dx.doi.org/10.1093/hmg/dds134DOI Listing
July 2012

The ADAMTS1 protease gene is required for mammary tumor growth and metastasis.

Am J Pathol 2011 Dec 12;179(6):3075-85. Epub 2011 Oct 12.

School of Paediatrics and Reproductive Health, Robinson Institute, University of Adelaide, Adelaide, South Australia, Australia.

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http://dx.doi.org/10.1016/j.ajpath.2011.08.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260838PMC
December 2011

Do RCAN1 proteins link chronic stress with neurodegeneration?

FASEB J 2011 Oct 16;25(10):3306-11. Epub 2011 Jun 16.

Ethel Percy Andrus Gerontology Center, Davis School of Gerontology, University of Southern California, 3715 McClintock Ave., Los Angeles, CA 90089-0191, USA.

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http://dx.doi.org/10.1096/fj.11-185728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971512PMC
October 2011

The Ets transcription factor ELF5 functions as a tumor suppressor in the kidney.

Twin Res Hum Genet 2011 Aug;14(4):316-22

Centre for Functional Genomics and Human Disease, Monash Institute of Medical Research, Monash University, Australia.

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http://www.journals.cambridge.org/abstract_S1832427400011518
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http://dx.doi.org/10.1375/twin.14.4.316DOI Listing
August 2011

Transcript profiling of Elf5+/- mammary glands during pregnancy identifies novel targets of Elf5.

PLoS One 2010 Oct 7;5(10):e13150. Epub 2010 Oct 7.

Centre for Functional Genomics and Human Disease, Monash Institute of Medical Research, Clayton, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013150PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951341PMC
October 2010

Mice deficient for the chromosome 21 ortholog Itsn1 exhibit vesicle-trafficking abnormalities.

Hum Mol Genet 2008 Nov 2;17(21):3281-90. Epub 2008 Aug 2.

Departments of Biochemistry and Molecular Biology and Anatomy and Developmental Biology, Monash University, Building 13C, Wellington Rd, Clayton 3168, Victoria, Australia.

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http://dx.doi.org/10.1093/hmg/ddn224DOI Listing
November 2008

Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation.

Cell Res 2008 Jun;18(6):649-63

Department of Physiology and Experimental Medicine and Canadian Institutes of Health Research Group in Lung Development, The Hospital for Sick Children, The University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada.

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http://dx.doi.org/10.1038/cr.2008.57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494831PMC
June 2008

DSCR1/RCAN1 regulates vesicle exocytosis and fusion pore kinetics: implications for Down syndrome and Alzheimer's disease.

Hum Mol Genet 2008 Apr 7;17(7):1020-30. Epub 2008 Jan 7.

Molecular and Cellular Neuroscience Group, Department of Human Physiology and Centre for Neuroscience, Flinders University, Adelaide, Australia.

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http://dx.doi.org/10.1093/hmg/ddm374DOI Listing
April 2008

TGF-betaRII rescues development of small intestinal epithelial cells in Elf3-deficient mice.

Gastroenterology 2007 Apr 25;132(4):1410-9. Epub 2007 Feb 25.

Centre for Functional Genomics and Human Disease, Monash Institute of Medical Research, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1053/j.gastro.2007.02.054DOI Listing
April 2007

Alzheimer's disease and endocytic dysfunction: clues from the Down syndrome-related proteins, DSCR1 and ITSN1.

Ageing Res Rev 2006 Nov 26;5(4):388-401. Epub 2006 Jan 26.

Prince Henry's Institute of Medical Research, Clayton, Vic., Australia.

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http://dx.doi.org/10.1016/j.arr.2005.11.001DOI Listing
November 2006

ADAMTS-1-knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo.

Arthritis Rheum 2005 May;52(5):1461-72

Arthritis Research Group, University of Melbourne, Royal Children's Hospital, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1002/art.21022DOI Listing
May 2005

Neonatal calyceal dilation and renal fibrosis resulting from loss of Adamts-1 in mouse kidney is due to a developmental dysgenesis.

Nephrol Dial Transplant 2005 Feb 22;20(2):419-23. Epub 2004 Dec 22.

Monash Institute of Reproduction and Development, Monash University, Clayton 3168, Victoria, Australia.

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https://academic.oup.com/ndt/article-lookup/doi/10.1093/ndt/
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http://dx.doi.org/10.1093/ndt/gfh603DOI Listing
February 2005

Tissue-specific overexpression of the HSA21 gene GABPalpha: implications for DS.

Biochim Biophys Acta 2004 Dec;1739(1):81-7

Centre for Functional Genomics and Human Disease, Monash Institute of Reproduction and Development, Monash University, Clayton, Victoria 3168, Australia.

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http://dx.doi.org/10.1016/j.bbadis.2004.09.005DOI Listing
December 2004

A major site of expression of the ets transcription factor Elf5 is epithelia of exocrine glands.

Histochem Cell Biol 2004 Dec 3;122(6):521-6. Epub 2004 Nov 3.

Centre for Functional Genomics and Human Disease, Monash Institute of Reproduction and Development, Monash University, 27-31 Wright Street, 3168, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1007/s00418-004-0713-xDOI Listing
December 2004