Meiru Hu

Meiru Hu

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Meiru Hu

Meiru Hu

Publications by authors named "Meiru Hu"

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LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflammatory responses.

Sci Rep 2019 Nov 12;9(1):16600. Epub 2019 Nov 12.

Institute of Military Cognitive and Brain Sciences, 27 Taiping Road, Beijing, 100850, People's Republic of China.

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http://dx.doi.org/10.1038/s41598-019-53247-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851103PMC
November 2019

MAPK/AP-1 pathway activation mediates AT1R upregulation and vascular endothelial cells dysfunction under PM2.5 exposure.

Ecotoxicol Environ Saf 2019 Apr 5;170:188-194. Epub 2018 Dec 5.

Department of Neuroimmunology, Beijing Institute of Brain Sciences, 27 Taiping Road, Beijing 100850, PR China; Anhui Medical University, 81 Meishan Road, Hefei 230032, PR China; Guangxi Medical University, 22 Shuangyong Road, Nanning 530021, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01476513183126
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http://dx.doi.org/10.1016/j.ecoenv.2018.11.124DOI Listing
April 2019

Transcriptional repression of IKKβ by p53 in arsenite-induced GADD45α accumulation and apoptosis.

Oncogene 2019 01 3;38(5):731-746. Epub 2018 Sep 3.

Department of Neuroimmunology, Beijing Institute of Brain Sciences, 27 Taiping Road, Beijing, 100850, China.

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http://dx.doi.org/10.1038/s41388-018-0478-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355650PMC
January 2019

Arsenite Induces Vascular Endothelial Cell Dysfunction by Activating IRE1α/XBP1s/HIF1α-Dependent ANGII Signaling.

Toxicol Sci 2017 Dec;160(2):315-328

Department of Stress Medicine, Beijing Institute of Basic Medical Sciences, Beijing 100850, China.

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http://dx.doi.org/10.1093/toxsci/kfx184DOI Listing
December 2017

IRE1α/XBP1s branch of UPR links HIF1α activation to mediate ANGII-dependent endothelial dysfunction under particulate matter (PM) 2.5 exposure.

Sci Rep 2017 10 18;7(1):13507. Epub 2017 Oct 18.

Department of Stress Medicine, Beijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing, 100850, P. R. China.

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http://dx.doi.org/10.1038/s41598-017-13156-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647447PMC
October 2017

Src/STAT3-dependent heme oxygenase-1 induction mediates chemoresistance of breast cancer cells to doxorubicin by promoting autophagy.

Cancer Sci 2015 Aug 4;106(8):1023-32. Epub 2015 Jul 4.

Department of Stress Medicine, Beijing Institute of Basic Medical Sciences, Beijing, China.

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http://dx.doi.org/10.1111/cas.12712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556392PMC
August 2015

AP-1 activation attenuates the arsenite-induced apoptotic response in human bronchial epithelial cells by up-regulating HO-1 expression.

Biotechnol Lett 2014 Oct 17;36(10):1927-36. Epub 2014 Jun 17.

Department of New Drug Screening Center, China Pharmaceutical University, No. 24 Tongjiaxiang, Nanjing, 210009, People's Republic of China.

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http://dx.doi.org/10.1007/s10529-014-1560-zDOI Listing
October 2014

Adrenergic signaling promotes angiogenesis through endothelial cell-tumor cell crosstalk.

Endocr Relat Cancer 2014 Oct;21(5):783-95

Department of PathophysiologyInstitute of Basic Medical Sciences, Beijing 100850, People's Republic of China

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http://dx.doi.org/10.1530/ERC-14-0236DOI Listing
October 2014

β2-AR-induced Her2 transactivation mediated by Erbin confers protection from apoptosis in cardiomyocytes.

Int J Cardiol 2013 Aug 6;167(4):1570-7. Epub 2012 May 6.

Department of Pathophysiology, Institute of Basic Medical Sciences, Beijing 100850, PR China.

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http://dx.doi.org/10.1016/j.ijcard.2012.04.093DOI Listing
August 2013

Catecholamine-Induced β2-adrenergic receptor activation mediates desensitization of gastric cancer cells to trastuzumab by upregulating MUC4 expression.

J Immunol 2013 Jun 29;190(11):5600-8. Epub 2013 Apr 29.

Department of Pathophysiology, Institute of Basic Medical Sciences, Beijing 100850, People's Republic of China.

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http://dx.doi.org/10.4049/jimmunol.1202364DOI Listing
June 2013

Ribosomal protein S7 regulates arsenite-induced GADD45α expression by attenuating MDM2-mediated GADD45α ubiquitination and degradation.

Nucleic Acids Res 2013 May 5;41(10):5210-22. Epub 2013 Apr 5.

Department of Pathophysiology, Beijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, PR China.

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http://dx.doi.org/10.1093/nar/gkt223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664810PMC
May 2013

p85α mediates NFAT3-dependent VEGF induction in the cellular UVB response.

J Cell Sci 2013 Mar 6;126(Pt 6):1317-22. Epub 2013 Feb 6.

Department of Pathophysiology, Beijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, P. R. China.

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http://dx.doi.org/10.1242/jcs.115550DOI Listing
March 2013

Glucocorticoid regulation of a novel HPV-E6-p53-miR-145 pathway modulates invasion and therapy resistance of cervical cancer cells.

J Pathol 2012 Oct 18;228(2):148-57. Epub 2012 Apr 18.

Department of Molecular Immunology, Institute of Basic Medical Sciences, Beijing, People's Republic of China.

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http://dx.doi.org/10.1002/path.3997DOI Listing
October 2012

IKKα contributes to UVB-induced VEGF expression by regulating AP-1 transactivation.

Nucleic Acids Res 2012 Apr 14;40(7):2940-55. Epub 2011 Dec 14.

Department of Pathophysiology, Beijing Institute of Basic Medical Sciences, Beijing 100850, P R China.

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http://dx.doi.org/10.1093/nar/gkr1216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326327PMC
April 2012

Modulation of IFN-γ receptor 1 expression by AP-2α influences IFN-γ sensitivity of cancer cells.

Am J Pathol 2012 Feb 16;180(2):661-71. Epub 2011 Dec 16.

Department of Molecular Immunology, Institute of Basic Medical Sciences, Beijing, China.

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http://dx.doi.org/10.1016/j.ajpath.2011.10.040DOI Listing
February 2012

IKKβ downregulation is critical for triggering JNKs-dependent cell apoptotic response in the human hepatoma cells under arsenite exposure.

Mol Cell Biochem 2011 Dec 19;358(1-2):61-6. Epub 2011 Jun 19.

Department of Cellular Immunology, Beijing Institute of Basic Medical Sciences, Beijing 100850, People's Republic of China.

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http://dx.doi.org/10.1007/s11010-011-0921-3DOI Listing
December 2011

The β2-adrenergic receptor and Her2 comprise a positive feedback loop in human breast cancer cells.

Breast Cancer Res Treat 2011 Jan 17;125(2):351-62. Epub 2010 Mar 17.

Department of Molecular Immunology, Institute of Basic Medical Sciences, Beijing, People's Republic of China.

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http://dx.doi.org/10.1007/s10549-010-0822-2DOI Listing
January 2011

Catecholamine up-regulates MMP-7 expression by activating AP-1 and STAT3 in gastric cancer.

Mol Cancer 2010 Oct 12;9:269. Epub 2010 Oct 12.

Department of Molecular Immunology, Institute of Basic Medical Sciences, Beijing 100850, PR China.

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http://dx.doi.org/10.1186/1476-4598-9-269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964618PMC
October 2010

Transactivators Zta and Rta of Epstein-Barr virus promote G0/G1 to S transition in Raji cells: a novel relationship between lytic virus and cell cycle.

Mol Immunol 2010 May 24;47(9):1783-92. Epub 2010 Mar 24.

Institute of Basic Medicine, Shandong Academy of Medical Science, Key Medical Laboratory for Tumor Immunology and Chinese Medicine Immunology of Shandong Province, Jinan 250062, PR China.

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http://dx.doi.org/10.1016/j.molimm.2010.02.017DOI Listing
May 2010

GADD45alpha mediates arsenite-induced cell apoptotic effect in human hepatoma cells via JNKs/AP-1-dependent pathway.

J Cell Biochem 2010 Apr;109(6):1264-73

Department of Cellular Immunology, Beijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, PR China.

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http://dx.doi.org/10.1002/jcb.22509DOI Listing
April 2010

Construction and expression of a spliced variant of Epstein-Barr virus bzlf1 and preparation of its polyclonal antibody.

Prep Biochem Biotechnol 2010 ;40(1):46-56

Institute of Basic Medical Sciences, Beijing, PR China.

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http://dx.doi.org/10.1080/10826060903392780DOI Listing
March 2010

A novel role of IKKalpha in the mediation of UVB-induced G0/G1 cell cycle arrest response by suppressing Cyclin D1 expression.

Biochim Biophys Acta 2010 Feb 15;1803(2):323-32. Epub 2010 Jan 15.

Department of Cellular Immunology, Beijing Institute of Basic Medical Sciences, Beijing 100850, People's Republic of China.

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http://dx.doi.org/10.1016/j.bbamcr.2010.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850076PMC
February 2010

Down-regulation of MHC class II expression through inhibition of CIITA transcription by lytic transactivator Zta during Epstein-Barr virus reactivation.

J Immunol 2009 Feb;182(4):1799-809

Department of Molecular Immunology, Institute of Basic Medical Sciences, Beijing, People's Republic of China;

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http://dx.doi.org/10.4049/jimmunol.0802686DOI Listing
February 2009

Heregulin-beta promotes matrix metalloproteinase-7 expression via HER2-mediated AP-1 activation in MCF-7 cells.

Mol Cell Biochem 2008 Nov 4;318(1-2):73-9. Epub 2008 Jul 4.

Institute of Basic Medical Sciences, Beijing, 100850, People's Republic of China.

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http://dx.doi.org/10.1007/s11010-008-9858-6DOI Listing
November 2008

In vitro and in vivo antitumor effect of a trivalent bispecific antibody targeting ErbB2 and CD16.

Cancer Biol Ther 2008 Nov 4;7(11):1744-50. Epub 2008 Nov 4.

Institute of Basic Medical Sciences, Beijing, PR China.

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http://dx.doi.org/10.4161/cbt.7.11.6725DOI Listing
November 2008

HER2-dependent MMP-7 expression is mediated by activated STAT3.

Cell Signal 2008 Jul 4;20(7):1284-91. Epub 2008 Mar 4.

Institute of Basic Medical Sciences, Beijing 100850, PR China.

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http://dx.doi.org/10.1016/j.cellsig.2008.02.017DOI Listing
July 2008

Both IKKalpha and IKKbeta are implicated in the arsenite-induced AP-1 transactivation correlating with cell apoptosis through NF-kappaB activity-independent manner.

Exp Cell Res 2008 Jul 11;314(11-12):2187-98. Epub 2008 Apr 11.

Nelson Institute of Environmental Medicine, New York University School of Medicine, 57 Old Forge Road, Tuxedo, NY 10987, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00144827080015
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http://dx.doi.org/10.1016/j.yexcr.2008.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587112PMC
July 2008

Serum proteomic-based analysis for the identification of a potential serological marker for autoimmune hepatitis.

Biochem Biophys Res Commun 2008 Mar 26;367(2):284-90. Epub 2007 Dec 26.

School of Preclinical and Forensic Medicine, West China Medical Center of Sichuan University, Chengdu 610041, PR China.

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http://dx.doi.org/10.1016/j.bbrc.2007.12.075DOI Listing
March 2008

Fra-1 and Stat3 synergistically regulate activation of human MMP-9 gene.

Mol Immunol 2008 Jan 18;45(1):137-43. Epub 2007 Jun 18.

Institute of Basic Medical Sciences, Beijing 100850, PR China.

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http://dx.doi.org/10.1016/j.molimm.2007.04.031DOI Listing
January 2008

Mutational analysis of ErbB2 intracellular localization.

Histochem Cell Biol 2007 Nov 12;128(5):473-83. Epub 2007 Sep 12.

Institute of Basic Medical Sciences, Taiping Road 27, Beijing, 100850, People's Republic of China.

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http://dx.doi.org/10.1007/s00418-007-0329-zDOI Listing
November 2007

c-Jun, a crucial molecule in metastasis of breast cancer and potential target for biotherapy.

Oncol Rep 2007 Nov;18(5):1207-12

Institute of Basic Medical Sciences, Taiping Road 27, Beijing 100850, P.R. China.

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November 2007

Expression and distribution of HSP27 in response to G418 in different human breast cancer cell lines.

Histochem Cell Biol 2006 Nov 30;126(5):593-601. Epub 2006 May 30.

Department of Cellular Immunology, Institute of Basic Medical Sciences, Taiping Road 27, Beijing 100850, People's Republic of China.

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http://dx.doi.org/10.1007/s00418-006-0195-0DOI Listing
November 2006

A novel neutralizing monoclonal antibody against both ricin toxin A and ricin toxin B, and application of a rapid sandwich enzyme-linked immunosorbent assay.

Hybridoma (Larchmt) 2006 Aug;25(4):225-9

Department of Molecular Immunology, Institute of Basic Medical Sciences, Beijing, P.R. China.

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http://dx.doi.org/10.1089/hyb.2006.25.225DOI Listing
August 2006

A novel cis-acting element in Her2 promoter regulated by Stat3 in mammary cancer cells.

Biochem Biophys Res Commun 2006 Jun 4;345(2):660-8. Epub 2006 May 4.

Institute of Basic Medical Sciences, Taiping Road 27, Beijing 100850, PR China.

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http://dx.doi.org/10.1016/j.bbrc.2006.04.153DOI Listing
June 2006

A novel designed single domain antibody on 3-D structure of ricin A chain remarkably blocked ricin-induced cytotoxicity.

Mol Immunol 2006 Apr 15;43(11):1912-9. Epub 2005 Dec 15.

Institute of Basic Medical Sciences, Department of Molecular Immunology, P.O. Box 130 (3), Taiping Road, Beijing 100850, PR China.

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http://dx.doi.org/10.1016/j.molimm.2005.10.012DOI Listing
April 2006

In vivo identification of the interaction site of ErbB2 extracellular domain with its autoinhibitor.

J Cell Physiol 2005 Dec;205(3):335-43

Institute of Basic Medical Sciences, Beijing, China.

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http://dx.doi.org/10.1002/jcp.20409DOI Listing
December 2005

Structure-based design and characterization of a Novel IL-6 antagonist peptide.

Mol Immunol 2005 May 23;42(9):1015-21. Epub 2004 Nov 23.

Institute of Basic Medical Sciences, P.O. Box 130 (3), Taiping Road, Beijing 100850, PR China.

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http://dx.doi.org/10.1016/j.molimm.2004.09.033DOI Listing
May 2005

A new format of bispecific antibody: highly efficient heterodimerization, expression and tumor cell lysis.

J Immunol Methods 2005 Jan 19;296(1-2):95-101. Epub 2004 Nov 19.

Department of Molecular Immunology, Beijing Institute of Basic Medical Sciences, Taiping Road 27, Beijing 100850, China.

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http://dx.doi.org/10.1016/j.jim.2004.11.005DOI Listing
January 2005

A novel hIL-6 antagonist peptide from computer-aided design contributes to suppression of apoptosis in M1 cells.

Biochem Biophys Res Commun 2004 Dec;325(2):518-24

Institute of Basic Medical Sciences, P.O. Box 130 (3), Taiping Road, Beijing 100850, PR China.

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http://dx.doi.org/10.1016/j.bbrc.2004.10.065DOI Listing
December 2004

Effects of inhibition of ubiquitin-proteasome pathway on human primary leukemic cells.

Sci China C Life Sci 2002 Dec;45(6):647-55

Institute of Basic Medical Sciences, Beijing, China.

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http://link.springer.com/10.1007/BF02879753
Publisher Site
http://dx.doi.org/10.1007/BF02879753DOI Listing
December 2002

Cleavage of Bcl-2 Protein by Activated Caspase-3 Is Associated with Inactivation of Lyn(p53/56) Kinase Activity in Human M-07e Leukemic Cells during Apoptosis.

Zhongguo Shi Yan Xue Ye Xue Za Zhi 2000 Sep;8(3):166-175

National Center of Biomedical Analysis, Beijing Institute of Basic Medical Sciences, Beijing 100850, China; Division of Hematology-Oncology, Department of Internal Medicine, and Barbara Ann Karmanos Cancer Institutes, Wayne State University School of Medicine, Detroit, Michigan 48201 USA.

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September 2000