Publications by authors named "Meir Glick"

67Publications

Diversity & tractability revisited in collaborative small molecule phenotypic screening library design.

Bioorg Med Chem 2020 01 20;28(1):115192. Epub 2019 Nov 20.

Computational & Structural Chemistry, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, MA 02115, USA. Electronic address:

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January 2020

Novel drug targets in 2018.

Nat Rev Drug Discov 2019 Mar 26. Epub 2019 Mar 26.

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March 2019

Data to Decisions: Creating a Culture of Model-Driven Drug Discovery.

AAPS J 2017 09 2;19(5):1255-1263. Epub 2017 Aug 2.

MRL Information Technology, Merck & Co., Inc., 470 Atlantic Avenue, Boston, Massachusetts, 02110, USA.

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September 2017

Deorphanization strategies for dark chemical matter.

Drug Discov Today Technol 2017 Mar 27;23:69-74. Epub 2017 Feb 27.

Chemistry Capabilities and Screening, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, MA 02115, USA.

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March 2017

Construction of a 3D-shaped, natural product like fragment library by fragmentation and diversification of natural products.

Bioorg Med Chem 2017 02 8;25(3):921-925. Epub 2016 Dec 8.

Novartis Institutes for BioMedical Research Inc., Basel, Switzerland. Electronic address:

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February 2017

Public Domain HTS Fingerprints: Design and Evaluation of Compound Bioactivity Profiles from PubChem's Bioassay Repository.

J Chem Inf Model 2016 Feb 14;56(2):390-8. Epub 2016 Jan 14.

Pfizer Inc. , 610 Main Street, Cambridge, Massachusetts 02139, United States.

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February 2016

Experimental design strategy: weak reinforcement leads to increased hit rates and enhanced chemical diversity.

J Chem Inf Model 2015 May 14;55(5):956-62. Epub 2015 May 14.

†Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.

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May 2015