Publications by authors named "Meinolf Karthaus"

69 Publications

Posaconazole versus voriconazole for primary treatment of invasive aspergillosis: a phase 3, randomised, controlled, non-inferiority trial.

Authors:
Johan A Maertens Galia Rahav Dong-Gun Lee Alfredo Ponce-de-León Isabel Cristina Ramírez Sánchez Nikolay Klimko Anne Sonet Shariq Haider Juan Diego Vélez Issam Raad Liang-Piu Koh Meinolf Karthaus Jianying Zhou Ronen Ben-Ami Mary R Motyl Seongah Han Anjana Grandhi Hetty Waskin

Lancet 2021 Feb;397(10273):499-509

Department of Infectious Disease, Merck & Co, Inc, Kenilworth, NJ, USA.

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February 2021

Patients with colorectal cancer and brain metastasis: The relevance of extracranial metastatic patterns predicting time intervals to first occurrence of intracranial metastasis and survival.

Authors:
Johannes Thurmaier Volker Heinemann Jutta Engel Gabriele Schubert-Fritschle Max Wiedemann Natascha C Nüssler Reinhard Ruppert Jörg Kleeff Wolfgang Schepp Florian Löhe Meinolf Karthaus Jens Neumann Jörg Kumbrink Francesco Taverna Arndt Stahler Kathrin Heinrich Christoph Benedikt Westphalen Julian W Holch Thomas Kirchner Marlies Michl

Int J Cancer 2021 Apr 2;148(8):1919-1927. Epub 2020 Dec 2.

Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.

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April 2021

Prophylaxis, diagnosis and therapy of infections in patients undergoing high-dose chemotherapy and autologous haematopoietic stem cell transplantation. 2020 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO).

Authors:
Maximilian Christopeit Martin Schmidt-Hieber Rosanne Sprute Dieter Buchheidt Marcus Hentrich Meinolf Karthaus Olaf Penack Markus Ruhnke Florian Weissinger Oliver A Cornely Georg Maschmeyer

Ann Hematol 2021 Feb 20;100(2):321-336. Epub 2020 Oct 20.

Klinikum Ernst von Bergmann, Department of Hematology, Oncology and Palliative Care, Potsdam, Germany.

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February 2021

Central venous catheter-related infections in hematology and oncology: 2020 updated guidelines on diagnosis, management, and prevention by the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO).

Authors:
Boris Böll Enrico Schalk Dieter Buchheidt Justin Hasenkamp Michael Kiehl Til Ramon Kiderlen Matthias Kochanek Michael Koldehoff Philippe Kostrewa Annika Y Claßen Sibylle C Mellinghoff Bernd Metzner Olaf Penack Markus Ruhnke Maria J G T Vehreschild Florian Weissinger Hans-Heinrich Wolf Meinolf Karthaus Marcus Hentrich

Ann Hematol 2021 Jan 30;100(1):239-259. Epub 2020 Sep 30.

Department of Hematology and Oncology, Red Cross Hospital Munich, Munich, Germany.

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January 2021

Real-world evidence of NEPA, netupitant-palonosetron, in chemotherapy-induced nausea and vomiting prevention: effects on quality of life.

Authors:
Meinolf Karthaus Gülten Oskay-Özcelik Pia Wülfing Carsten Hielscher Dagmar Guth Mark-Oliver Zahn Elisa Flahaut Jörg Schilling

Future Oncol 2020 05 16;16(14):939-953. Epub 2020 Apr 16.

Gynecological Oncology Practice, Berlin, Germany.

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May 2020

Phase 3 Study of Palonosetron IV Infusion Vs. IV Bolus for Chemotherapy-Induced Nausea and Vomiting Prophylaxis After Highly Emetogenic Chemotherapy.

Authors:
Meinolf Karthaus Daniel Voisin Giada Rizzi Tudor Ciuleanu

J Pain Symptom Manage 2020 09 8;60(3):568-576. Epub 2020 Apr 8.

Institute of Oncology Prof. Dr. Ion Chiricuţã and UMF Iuliu Haţieganu, Cluj-Napoca, Romania.

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September 2020

Treatment of invasive fungal diseases in cancer patients-Revised 2019 Recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO).

Authors:
Markus Ruhnke Oliver A Cornely Martin Schmidt-Hieber Nael Alakel Boris Boell Dieter Buchheidt Maximilian Christopeit Justin Hasenkamp Werner J Heinz Marcus Hentrich Meinolf Karthaus Michael Koldehoff Georg Maschmeyer Jens Panse Olaf Penack Jan Schleicher Daniel Teschner Andrew John Ullmann Maria Vehreschild Marie von Lilienfeld-Toal Florian Weissinger Stefan Schwartz

Mycoses 2020 Jul 12;63(7):653-682. Epub 2020 May 12.

Division of Haematology & Oncology, Department of Internal Medicine, Charité University Medicine, Campus Benjamin Franklin, Berlin, Germany.

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July 2020

Relationship Between Tumor Response and Tumor-Related Symptoms in RAS Wild-Type Metastatic Colorectal Cancer: Retrospective Analyses From 3 Panitumumab Trials.

Authors:
Julien Taieb Michael Geissler Fernando Rivera Meinolf Karthaus Richard Wilson Fotios Loupakis Timothy Price Michael Tracy Peter Burdon Marc Peeters

Clin Colorectal Cancer 2019 12 29;18(4):245-256.e5. Epub 2019 Jul 29.

Department of Oncology, Antwerp University Hospital, Edegem, Belgium.

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December 2019

Impact of Primary Tumour Location and Early Tumour Shrinkage on Outcomes in Patients with RAS Wild-Type Metastatic Colorectal Cancer Following First-Line FOLFIRI Plus Panitumumab.

Authors:
Claus-Henning Köhne Meinolf Karthaus Laurent Mineur Josef Thaler Marc Van den Eynde Javier Gallego Reija Koukakis Marloes Berkhout Ralf-Dieter Hofheinz

Drugs R D 2019 Sep;19(3):267-275

Tagestherapiezentrum, Interdisziplinäres Tumorzentrum, Universitätsmedizin Mannheim, Mannheim, Germany.

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September 2019

Aflibercept Plus FOLFIRI for Second-line Treatment of Metastatic Colorectal Cancer: Observations from the Global Aflibercept Safety and Health-Related Quality-of-Life Program (ASQoP).

Authors:
Rachel P Riechelmann Vichien Srimuninnimit Roberto Bordonaro Petr Kavan Maria Di Bartolomeo Evaristo Maiello Irfan Cicin Pilar García-Alfonso Ian Chau Mikhail Y Fedyanin Carlos Fernández Martos Mikhail Ter-Ovanesov Marc Peeters Yoo-Joung Ko Suayib Yalcin Meinolf Karthaus Jorge Aparicio Volker Heinemann Pascaline Picard Denise Bury Edward Drea Alberto Sobrero

Clin Colorectal Cancer 2019 09 15;18(3):183-191.e3. Epub 2019 May 15.

IRCCS Azienda Ospedaliera Universitaria San Martino, Genova, Italy.

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September 2019

Neurokinin-1 receptor antagonists: review of their role for the prevention of chemotherapy-induced nausea and vomiting in adults.

Authors:
Meinolf Karthaus Xaver Schiel Christina H Ruhlmann Luigi Celio

Expert Rev Clin Pharmacol 2019 Jul 13;12(7):661-680. Epub 2019 Jun 13.

d Department of Medical Oncology and Hematology , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.

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July 2019

Fixed combination of oral NEPA (netupitant-palonosetron) for the prevention of acute and delayed chemotherapy-induced nausea and vomiting in patients receiving multiple cycles of chemotherapy: Efficacy data from 2 randomized, double-blind phase III studies.

Authors:
Lee Schwartzberg Meinolf Karthaus Giorgia Rossi Giada Rizzi Maria E Borroni Hope S Rugo Karin Jordan Vincent Hansen

Cancer Med 2019 05 9;8(5):2064-2073. Epub 2019 Apr 9.

Northern Utah Associates, Ogden, Utah.

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May 2019

Safety profile of trifluridine/tipiracil monotherapy in clinical practice: results of the German compassionate-use program for patients with metastatic colorectal cancer.

Authors:
Stefan Kasper Jens Kisro Martin Fuchs Christian Müller Armin Schulz-Abelius Meinolf Karthaus Mohammad-Reza Rafiyan Alexander Stein

BMC Cancer 2018 Nov 16;18(1):1124. Epub 2018 Nov 16.

University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hubertus Wald Tumor Center, Hamburg, Germany.

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November 2018

Diagnosis of invasive fungal diseases in haematology and oncology: 2018 update of the recommendations of the infectious diseases working party of the German society for hematology and medical oncology (AGIHO).

Authors:
Markus Ruhnke Gerhard Behre Dieter Buchheidt Maximilian Christopeit Axel Hamprecht Werner Heinz Claus-Peter Heussel Marius Horger Oliver Kurzai Meinolf Karthaus Jürgen Löffler Georg Maschmeyer Olaf Penack Christina Rieger Volker Rickerts Jörg Ritter Martin Schmidt-Hieber Nikolai Schuelper Stefan Schwartz Andrew Ullmann Jörg Janne Vehreschild Marie von Lilienfeld-Toal Thomas Weber Hans H Wolf

Mycoses 2018 Nov 3;61(11):796-813. Epub 2018 Sep 3.

Department of Internal Medicine IV, Universitätsklinik Halle, Halle, Germany.

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November 2018

Exploratory pooled analysis evaluating the effect of sequence of biological therapies on overall survival in patients with wild-type metastatic colorectal carcinoma.

Authors:
Marc Peeters Frédéric Forget Meinolf Karthaus Manuel Valladares-Ayerbes Alberto Zaniboni Gaston Demonty Xuesong Guan Fernando Rivera

ESMO Open 2018 24;3(2):e000297. Epub 2018 Feb 24.

Department of Medical Oncology, Hospital Universitario Marqués de Valdecilla, Santander, Spain.

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February 2018

Phase II Study of the Dual EGFR/HER3 Inhibitor Duligotuzumab (MEHD7945A) versus Cetuximab in Combination with FOLFIRI in Second-Line Wild-Type Metastatic Colorectal Cancer.

Authors:
Andrew G Hill Michael P Findlay Matthew E Burge Christopher Jackson Pilar Garcia Alfonso Leslie Samuel Vinod Ganju Meinolf Karthaus Alessio Amatu Mark Jeffery Maria Di Bartolomeo John Bridgewater Andrew L Coveler Manuel Hidalgo Amy V Kapp Roxana I Sufan Bruce B McCall William D Hanley Elicia M Penuel Andrea Pirzkall Josep Tabernero

Clin Cancer Res 2018 05 5;24(10):2276-2284. Epub 2018 Mar 5.

Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, CIBERONC, Barcelona, Spain.

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May 2018

Author Correction: Exploratory analyses assessing the impact of early tumour shrinkage and depth of response on survival outcomes in patients with RAS wild-type metastatic colorectal cancer receiving treatment in three randomised panitumumab trials.

Authors:
Julien Taieb Fernando Rivera Salvatore Siena Meinolf Karthaus Manuel Valladares-Ayerbes Javier Gallego Michael Geissler Reija Koukakis Gaston Demonty Marc Peeters

J Cancer Res Clin Oncol 2018 04;144(4):795-797

Antwerp University Hospital, Antwerp, Belgium.

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April 2018

Exploratory analyses assessing the impact of early tumour shrinkage and depth of response on survival outcomes in patients with RAS wild-type metastatic colorectal cancer receiving treatment in three randomised panitumumab trials.

Authors:
Julien Taieb Fernando Rivera Salvatore Siena Meinolf Karthaus Manuel Valladares-Ayerbes Javier Gallego Michael Geissler Reija Koukakis Gaston Demonty Marc Peeters

J Cancer Res Clin Oncol 2018 Feb 28;144(2):321-335. Epub 2017 Oct 28.

Antwerp University Hospital, Antwerp, Belgium.

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February 2018

Final analysis of the randomised PEAK trial: overall survival and tumour responses during first-line treatment with mFOLFOX6 plus either panitumumab or bevacizumab in patients with metastatic colorectal carcinoma.

Authors:
Fernando Rivera Meinolf Karthaus J Randolph Hecht Isabel Sevilla Frédéric Forget Gianpiero Fasola Jean-Luc Canon Xuesong Guan Gaston Demonty Lee S Schwartzberg

Int J Colorectal Dis 2017 Aug 19;32(8):1179-1190. Epub 2017 Apr 19.

West Clinic, Memphis, TN, USA.

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August 2017

Dermatux: phase IV trial of Cetuximab plus FOLFIRI in first-line metastatic colorectal cancer receiving a pre-defined skin care.

Authors:
Carl Christoph Schimanski Frank Staib Thomas Göhler Holger Hebart Michael Heike Michael Neise Jochen Rudi Thomas Geer Gerrit Dingeldein Claudia Lang Peter Ehscheidt Thomas Flohr Klaus Maria Josten Meinolf Karthaus Alexander Schmittel Jan Wierecky Emil Boller Martin Indorf Marcus-Alexander Wörns Peter R Galle Markus Moehler

J Cancer Res Clin Oncol 2017 Jun 14;143(6):1023-1034. Epub 2017 Feb 14.

1. Med. Klinik, Universitätsmedizin Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.

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June 2017

Epidemiology of invasive aspergillosis and azole resistance in patients with acute leukaemia: the SEPIA Study.

Authors:
Philipp Koehler Axel Hamprecht Oliver Bader Isabelle Bekeredjian-Ding Dieter Buchheidt Gottfried Doelken Johannes Elias Gerhard Haase Corinna Hahn-Ast Meinolf Karthaus Alexander Kekulé Peter Keller Michael Kiehl Stefan W Krause Carolin Krämer Silke Neumann Holger Rohde Paul La Rosée Markus Ruhnke Philippe Schafhausen Enrico Schalk Katrin Schulz Stefan Schwartz Gerda Silling Peter Staib Andrew Ullmann Maria Vergoulidou Thomas Weber Oliver A Cornely Maria J G T Vehreschild

Int J Antimicrob Agents 2017 Feb 12;49(2):218-223. Epub 2016 Dec 12.

Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany; German Centre for Infection Research, Partner Site Bonn-Cologne, Cologne, Germany. Electronic address:

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February 2017

NEPA, a fixed oral combination of netupitant and palonosetron, improves control of chemotherapy-induced nausea and vomiting (CINV) over multiple cycles of chemotherapy: results of a randomized, double-blind, phase 3 trial versus oral palonosetron.

Authors:
Matti Aapro Meinolf Karthaus Lee Schwartzberg Igor Bondarenko Tomasz Sarosiek Cristina Oprean Servando Cardona-Huerta Vincent Hansen Giorgia Rossi Giada Rizzi Maria Elisa Borroni Hope Rugo

Support Care Cancer 2017 04 24;25(4):1127-1135. Epub 2016 Nov 24.

Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.

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April 2017

Impact of tumour RAS/BRAF status in a first-line study of panitumumab + FOLFIRI in patients with metastatic colorectal cancer.

Authors:
Meinolf Karthaus Ralf-Dieter Hofheinz Laurent Mineur Henry Letocha Richard Greil Josef Thaler Eva Fernebro Kelly S Oliner Michael Boedigheimer Brian Twomey Ying Zhang Gaston Demonty Claus-Henning Köhne

Br J Cancer 2016 Nov 20;115(10):1215-1222. Epub 2016 Oct 20.

Onkologie Klinikum Oldenburg, Rahel-Straus-Str. 10, 26133 Oldenburg, Germany.

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November 2016

Isavuconazole versus voriconazole for primary treatment of invasive mould disease caused by Aspergillus and other filamentous fungi (SECURE): a phase 3, randomised-controlled, non-inferiority trial.

Authors:
Johan A Maertens Issam I Raad Kieren A Marr Thomas F Patterson Dimitrios P Kontoyiannis Oliver A Cornely Eric J Bow Galia Rahav Dionysios Neofytos Mickael Aoun John W Baddley Michael Giladi Werner J Heinz Raoul Herbrecht William Hope Meinolf Karthaus Dong-Gun Lee Olivier Lortholary Vicki A Morrison Ilana Oren Dominik Selleslag Shmuel Shoham George R Thompson Misun Lee Rochelle M Maher Anne-Hortense Schmitt-Hoffmann Bernhardt Zeiher Andrew J Ullmann

Lancet 2016 Feb 10;387(10020):760-9. Epub 2015 Dec 10.

Julius-Maximilians-University, Department of Internal Medicine II, Infectious Diseases, Würzburg, Germany. Electronic address:

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February 2016

[Tumor dynamics: parameters for the overall benefit of therapy].

Authors:
Meinolf Karthaus

Oncol Res Treat 2015 ;38(5):258-9

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February 2016

Brain Metastasis in Colorectal Cancer Patients: Survival and Analysis of Prognostic Factors.

Authors:
Marlies Michl Johannes Thurmaier Gabriele Schubert-Fritschle Max Wiedemann Rüdiger P Laubender Natascha C Nüssler Reinhard Ruppert Jörg Kleeff Wolfgang Schepp Clemens Reuter Florian Löhe Meinolf Karthaus Jens Neumann Thomas Kirchner Jutta Engel Volker Heinemann

Clin Colorectal Cancer 2015 Dec 6;14(4):281-90. Epub 2015 Jun 6.

Department of Hematology and Medical Oncology, Klinikum Grosshadern and Comprehensive Cancer Center Munich (CCCM), Ludwig-Maximilians-University of Munich, Munich, Germany.

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December 2015

Panitumumab in Metastatic Colorectal Cancer: The Importance of Tumour RAS Status.

Authors:
Marc Peeters Meinolf Karthaus Fernando Rivera Jan-Henrik Terwey Jean-Yves Douillard

Drugs 2015 May;75(7):731-48

Department of Oncology, Antwerp University Hospital, Wilrijkstraat 10, 2650, Edegem, Belgium,

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May 2015

Efficacy and safety of oral palonosetron compared with IV palonosetron administered with dexamethasone for the prevention of chemotherapy-induced nausea and vomiting (CINV) in patients with solid tumors receiving cisplatin-based highly emetogenic chemotherapy (HEC).

Authors:
Meinolf Karthaus Csőszi Tibor Vito Lorusso Rajender Singh-Arora Alexander Filippov Giada Rizzi Maria Elisa Borroni Giorgia Rossi Steven M Grunberg

Support Care Cancer 2015 Oct 28;23(10):2917-23. Epub 2015 Feb 28.

Department of Hematology and Oncology, Klinikum Neuperlach, Munich, Germany,

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October 2015

Therapeutic drug monitoring in the treatment of invasive aspergillosis with voriconazole in cancer patients--an evidence-based approach.

Authors:
Meinolf Karthaus Thomas Lehrnbecher Hans-Peter Lipp Stefan Kluge Dieter Buchheidt

Ann Hematol 2015 Apr 20;94(4):547-56. Epub 2015 Feb 20.

Medical Clinic IV, Hematology and Oncology, Neuperlach Hospital, Munich, Germany,

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April 2015

Review of oral fixed-dose combination netupitant and palonosetron (NEPA) for the treatment of chemotherapy-induced nausea and vomiting.

Authors:
Vito Lorusso Meinolf Karthaus Matti Aapro

Future Oncol 2015 31;11(4):565-77. Epub 2014 Oct 31.

Medical Oncology Unit, National Cancer Institute Giovanni Paolo II, 70124 Bari, Italy.

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October 2015