Publications by authors named "Mehrdad Nikfarjam"

100Publications

Outcomes of endoscopic ultrasound as a one-off pancreatic cancer screening tool for 122 high- and moderate-risk patients.

JGH Open 2020 Dec 17;4(6):1217-1223. Epub 2020 Oct 17.

Endoscopy Unit, Department of Gastroenterology and Hepatology Austin Health Melbourne Victoria Australia.

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December 2020

Cannabinoids Inhibited Pancreatic Cancer via P-21 Activated Kinase 1 Mediated Pathway.

Int J Mol Sci 2020 Oct 28;21(21). Epub 2020 Oct 28.

Department of Surgery, University of Melbourne, Austin Health, Heidelberg, VIC 3084, Australia.

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October 2020

The Protective Effect of Zinc Against Liver Ischaemia Reperfusion Injury in a Rat Model of Global Ischaemia.

J Clin Exp Hepatol 2020 May-Jun;10(3):228-235. Epub 2019 Jul 24.

Department of Surgery, The University of Melbourne, Victoria, Australia.

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July 2019

Incidence and predictors of common bile duct stones in patients with acute cholecystitis: a systematic literature review and meta-analysis.

ANZ J Surg 2020 09 19;90(9):1598-1603. Epub 2019 Nov 19.

Department of Surgery, The University of Melbourne, Austin Health, Melbourne, Victoria, Australia.

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September 2020

Genomic Profiling of Biliary Tract Cancer Cell Lines Reveals Molecular Subtypes and Actionable Drug Targets.

iScience 2019 Nov 31;21:624-637. Epub 2019 Oct 31.

Olivia Newton John Cancer Research Institute, Austin Health, Level 5 ONJ Centre, 145 Studley Road, Heidelberg, Melbourne, VIC 3084, Australia; School of Cancer Medicine, La Trobe University, Melbourne, VIC 3084, Australia; Department of Medicine, The University of Melbourne, Melbourne, VIC 3052, Australia. Electronic address:

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November 2019

Quantitation and chemical coding of enteroendocrine cell populations in the human jejunum.

Cell Tissue Res 2020 Jan 2;379(1):109-120. Epub 2019 Sep 2.

Department of Anatomy & Neuroscience, University of Melbourne, Parkville, Victoria, 3010, Australia.

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January 2020

PAK inhibition by PF-3758309 enhanced the sensitivity of multiple chemotherapeutic reagents in patient-derived pancreatic cancer cell lines.

Am J Transl Res 2019 15;11(6):3353-3364. Epub 2019 Jun 15.

Department of Surgery, University of Melbourne, Austin Health Studley Road, Heidelberg, Victoria 3084, Australia.

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June 2019

Health economic implications of postoperative complications following liver resection surgery: a systematic review.

ANZ J Surg 2019 12 13;89(12):1561-1566. Epub 2019 May 13.

Department of Anaesthesia, Austin Hospital, Melbourne, Victoria, Australia.

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December 2019

Outcomes of central hepatectomy versus extended hepatectomy.

Hepatobiliary Pancreat Dis Int 2019 Jun 26;18(3):249-254. Epub 2019 Mar 26.

Department of Surgery, University of Melbourne, Austin Health, Heidelberg, Melbourne, Victoria, Australia. Electronic address:

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June 2019

Antitumor effects of all-trans retinoic acid and its synergism with gemcitabine are associated with downregulation of p21-activated kinases in pancreatic cancer.

Am J Physiol Gastrointest Liver Physiol 2019 05 7;316(5):G632-G640. Epub 2019 Mar 7.

Department of Surgery, University of Melbourne, Austin Health, Heidelberg, Melbourne, Victoria , Australia.

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May 2019

Potential Use of Cannabinoids for the Treatment of Pancreatic Cancer.

J Pancreat Cancer 2019 25;5(1):1-7. Epub 2019 Jan 25.

Department of Surgery, University of Melbourne, Austin Health, Melbourne, Australia.

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January 2019

p21-activated kinase signalling in pancreatic cancer: New insights into tumour biology and immune modulation.

World J Gastroenterol 2018 Sep;24(33):3709-3723

Department of Surgery, University of Melbourne, Melbourne 3084, Australia.

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September 2018

Functions of the CXC ligand family in the pancreatic tumor microenvironment.

Pancreatology 2018 Oct 1;18(7):705-716. Epub 2018 Aug 1.

Department of Surgery, University of Melbourne, Austin Health, Melbourne, Victoria, Australia. Electronic address:

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October 2018

Metastatic clear cell renal cell carcinoma demonstrating intense uptake on Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature.

World J Nucl Med 2018 Jul-Sep;17(3):195-197

Department of Molecular Imaging and Therapy, University of Melbourne, Austin Health, Melbourne, Victoria, Australia.

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July 2018

The outcomes of central hepatectomy versus extended hepatectomy: a systematic review and meta-analysis.

HPB (Oxford) 2018 06 10;20(6):487-496. Epub 2018 Feb 10.

University of Melbourne Department of Surgery, Austin Health, Heidelberg, Victoria, Australia. Electronic address:

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June 2018

The cost of perioperative complications following pancreaticoduodenectomy: A systematic review.

Pancreatology 2018 Mar 19;18(2):208-220. Epub 2017 Dec 19.

Department of Anaesthesia, Austin Hospital, Heidelberg, VIC 3084, Australia; University of Melbourne, Department of Surgery, Austin Hospital, Heidelberg, VIC 3084, Australia. Electronic address:

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March 2018

Health economic implications of complications associated with pancreaticoduodenectomy at a University Hospital: a retrospective cohort cost study.

HPB (Oxford) 2018 05 14;20(5):423-431. Epub 2017 Dec 14.

University of Melbourne, Department of Anaesthesia, Austin Health, Studley Road, Heidelberg, VIC 3084, Australia; Department of Surgery, University of Melbourne, Austin Health, Studley Road, Heidelberg, VIC 3084, Australia. Electronic address:

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May 2018

Inhibition of p21 activated kinase enhances tumour immune response and sensitizes pancreatic cancer to gemcitabine.

Int J Oncol 2018 Jan 7;52(1):261-269. Epub 2017 Nov 7.

Department of Surgery, University of Melbourne, Austin Health, Heidelberg, Victoria 3048, Australia.

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January 2018

Diagnosis and management of pancreatic exocrine insufficiency.

Med J Aust 2017 Aug;207(4):161-165

Kolling Institute, Royal North Shore Hospital, University of Sydney, Sydney, NSW.

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August 2017

Depletion of p21-activated kinase 1 up-regulates the immune system of APC mice and inhibits intestinal tumorigenesis.

BMC Cancer 2017 Jun 19;17(1):431. Epub 2017 Jun 19.

Department of Surgery, University of Melbourne, Austin Health, Studley Rd, Heidelberg, VIC, 3084, Australia.

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June 2017

The outcomes of pancreaticoduodenectomy in patients aged 80 or older: a systematic review and meta-analysis.

HPB (Oxford) 2017 06 11;19(6):475-482. Epub 2017 Mar 11.

University of Melbourne, Department of Surgery, Austin Health, Heidelberg, Victoria, Australia. Electronic address:

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June 2017

Inhibition of group 1 p21-activated kinases suppresses pancreatic stellate cell activation and increases survival of mice with pancreatic cancer.

Int J Cancer 2017 05 7;140(9):2101-2111. Epub 2017 Feb 7.

Department of Surgery, University of Melbourne. Austin Health, Melbourne, VIC, Australia.

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May 2017

Glaucarubinone Combined with Gemcitabine Improves Pancreatic Cancer Survival in an Immunocompetent Orthotopic Murine Model.

J Invest Surg 2016 Dec 30;29(6):366-372. Epub 2016 Mar 30.

a Department of Surgery , University of Melbourne, Austin Health , Melbourne , Victoria , Australia.

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December 2016

Intraoperative analysis of cross-talk inhibition between diaphragmatic and cardiac pacemakers.

BMJ Case Rep 2016 Jan 28;2016. Epub 2016 Jan 28.

Department of Anaesthesia, Austin Hospital, Heidelberg, Victoria, Australia Department of Surgery and Anaesthesia Perioperative Pain Medicine Unit, University of Melbourne, Melbourne, Victoria, Australia.

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January 2016

FRAX597, a PAK1 inhibitor, synergistically reduces pancreatic cancer growth when combined with gemcitabine.

BMC Cancer 2016 Jan 16;16:24. Epub 2016 Jan 16.

Department of Surgery, Austin Health, University of Melbourne, Heidelberg, VIC, Australia.

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January 2016

Postoperative wristwatch-induced compressive neuropathy of the hand: a case report.

J Med Case Rep 2015 Jun 16;9:141. Epub 2015 Jun 16.

Department of Surgery, Austin Hospital, Heidelberg, VIC, 3084, Australia.

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June 2015

The role of p21-activated kinases in pancreatic cancer.

Pancreas 2015 Apr;44(3):363-9

From the Department of Surgery, University of Melbourne, Austin Health, Heidelberg, Melbourne, Victoria, Australia.

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April 2015

Somatostatinoma of the minor papilla treated by local excision in a patient with neurofibromatosis type 1.

JOP 2015 Jan 31;16(1):81-4. Epub 2015 Jan 31.

Department of Surgery, University of Melbourne, Austin Health. Heidelberg, Melbourne, Victoria, Australia.

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January 2015

Laparoscopic partial splenectomy performed by monopolar saline-cooled radiofrequency coagulation.

J Laparoendosc Adv Surg Tech A 2014 Jul 11;24(7):502-5. Epub 2014 Jun 11.

1 Department of Surgery, University of Melbourne , Austin Health, Heidelberg, Melbourne, Victoria, Australia .

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July 2014

Glucagon-like peptide 1 and peptide YY are in separate storage organelles in enteroendocrine cells.

Cell Tissue Res 2014 Jul 20;357(1):63-9. Epub 2014 May 20.

Department of Anatomy & Neuroscience, University of Melbourne, Parkville, Victoria, 3010, Australia.

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July 2014

Total pancreatectomy for the treatment of pancreatic neoplasms.

ANZ J Surg 2014 Nov 22;84(11):823-6. Epub 2014 Apr 22.

Department of Surgery, Austin Health, University of Melbourne, Melbourne, Victoria, Australia.

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November 2014

Association of diabetes mellitus and pancreatic adenocarcinoma: a meta-analysis of 88 studies.

Ann Surg Oncol 2014 Jul 9;21(7):2453-62. Epub 2014 Mar 9.

Department of Surgery, University of Melbourne, Austin Health, LTB 8, 145 Studley Rd, Heidelberg, Melbourne, VIC, 3084, Australia.

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July 2014

Glaucarubinone and gemcitabine synergistically reduce pancreatic cancer growth via down-regulation of P21-activated kinases.

Cancer Lett 2014 May 31;346(2):264-72. Epub 2014 Jan 31.

Department of Surgery, University of Melbourne, Austin Health, Melbourne, Victoria 3084, Australia. Electronic address:

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May 2014

Percutaneous cholecystostomy for treatment of acute cholecystitis in the era of early laparoscopic cholecystectomy.

Surg Laparosc Endosc Percutan Tech 2013 Oct;23(5):474-80

Department of Surgery, Austin Health, University of Melbourne, Heidelberg, Melbourne, Vic., Australia.

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October 2013

Comparison of two syngeneic orthotopic murine models of pancreatic adenocarcinoma.

J Invest Surg 2013 Dec 19;26(6):352-9. Epub 2013 Aug 19.

1 Department of Surgery, Austin Health, University of Melbourne, Austin Health, LTB8, Heidleberg, Victoria, Australia.

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December 2013

Outcomes of cholecystectomy for treatment of acute cholecystitis in octogenarians.

ANZ J Surg 2014 Dec 1;84(12):943-8. Epub 2013 Aug 1.

Department of Surgery, University of Melbourne, Melbourne, Victoria, Australia.

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December 2014

Lymphatics and colorectal liver metastases: the case for sentinel node mapping.

HPB (Oxford) 2014 Feb 19;16(2):124-30. Epub 2013 Jul 19.

Department of Surgery, Austin Health, University of Melbourne, Heidelberg, Vic, Australia.

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February 2014

The utility of upfront double wire guided biliary cannulation following early unintentional pancreatic cannulation in patients undergoing ERCP.

Indian J Gastroenterol 2013 Sep 3;32(5):324-9. Epub 2013 May 3.

Department of Gastroenterology, Austin Health, University of Melbourne, Heidelberg, Melbourne, Victoria, Australia.

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September 2013

Improving outcomes for pancreatic cancer: radical surgery with patient-tailored, surgery-specific advanced haemodynamic monitoring.

BMJ Case Rep 2013 Apr 30;2013. Epub 2013 Apr 30.

Department of Anaesthesia, Austin Hospital, Heidelberg, Victoria, Australia.

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April 2013

Sex differences and outcomes of management of acute cholecystitis.

Surg Laparosc Endosc Percutan Tech 2013 Feb;23(1):61-5

Department of Surgery, Austin Health, University of Melbourne, Melbourne, VIC, Australia.

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February 2013

Biliary stenting versus surgical bypass for palliation of periampullary malignancy.

Indian J Gastroenterol 2013 Mar 16;32(2):82-9. Epub 2012 Nov 16.

University of Melbourne, Department of Surgery, Austin Health, LTB 8, Studley Road, Heidelberg, Melbourne, Victoria 3084, Australia.

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March 2013

Outcomes of patients with histologically proven acute acalculous cholecystitis.

ANZ J Surg 2012 Dec 3;82(12):918-22. Epub 2012 Sep 3.

Department of Surgery, Austin Health, University of Melbourne, Melbourne, Victoria, Australia.

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December 2012

Embryonal sarcoma of the liver in an adult patient.

Case Rep Surg 2012 29;2012:382723. Epub 2012 May 29.

Department of Pathology, The University of Melbourne, Austin Health, Heidelberg, Melbourne, VIC 3084, Australia.

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August 2012

Cystic duct clip migration into the common bile duct.

Indian J Gastroenterol 2012 Apr;31(2):86

Department of Surgery, University of Melbourne, Austin Hospital, LTB 8, Studley Rd, Heidelberg, Melbourne, Victoria 3084, Australia.

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April 2012

Direct diaphragm pacing stimulation.

ANZ J Surg 2011 Jul-Aug;81(7-8):496-8

Department of Surgery, University of Melbourne, Victoria, Australia.

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May 2012

Outcomes of contemporary management of gangrenous and non-gangrenous acute cholecystitis.

HPB (Oxford) 2011 Aug 3;13(8):551-8. Epub 2011 Jun 3.

Department of Surgery, Austin Health, University of Melbourne, Heidelberg, Melbourne, Vic., Australia.

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August 2011

Paraganglioma mimicking a pancreatic neoplasm.

JOP 2011 May 6;12(3):259-61. Epub 2011 May 6.

Department of Pathology, University of Melbourne, Austin Health, Heidelberg, VIC, Australia.

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May 2011

Pseudoaneurysm of the hepatic artery.

J Gastrointest Surg 2011 Oct 2;15(10):1899-901. Epub 2011 May 2.

Department of Surgery, University of Melbourne, Melbourne, Australia.

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October 2011

Concurrent lymphoma and pancreatic adenocarcinoma.

JOP 2011 Mar 9;12(2):185-9. Epub 2011 Mar 9.

Department of Surgery, University of Melbourne, Austin Health. Melbourne, Victoria, Australia.

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March 2011

Lymphatic patterns of colorectal liver metastases.

J Surg Res 2012 Apr 8;173(2):292-8. Epub 2010 Oct 8.

Department of Surgery, The University of Melbourne, Austin Hospital, Melbourne, Victoria, Australia.

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April 2012

The effect of surgical volume and the provision of residency and fellowship training on complications of major hepatic resection.

J Gastrointest Surg 2010 Dec 8;14(12):1981-9. Epub 2010 Sep 8.

Department of Surgery, Monash University, Maroondah Hospital, 1 Davey Drive Ringwood East, Victoria, 3135, Australia.

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December 2010

Combined pancreaticoduodenectomy and extended right hemicolectomy: outcomes and indications.

HPB (Oxford) 2009 Nov;11(7):559-64

Department of Surgery, Penn State Milton S. Hershey Medical Center, Penn State College of Medicine Hershey, PA, USA.

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November 2009

Pylorus preserving pancreaticoduodenectomy.

Saudi J Gastroenterol 2010 Apr-Jun;16(2):65

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June 2010

The diagnostic efficacy of natural orifice transluminal endoscopic surgery: is there a role in the intensive care unit?

Surg Endosc 2010 Oct 24;24(10):2485-91. Epub 2010 Mar 24.

Department of Surgery, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Lakeside Building 7th Floor, Cleveland, OH 44106, USA.

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October 2010

Peritoneal inflammatory response of natural orifice translumenal endoscopic surgery (NOTES) versus laparoscopy with carbon dioxide and air pneumoperitoneum.

Surg Endosc 2010 Jul 28;24(7):1727-36. Epub 2010 Jan 28.

Department of Surgery, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Lakeside Building 7th Floor, Cleveland, OH 44106, USA.

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July 2010

Human acellular dermal matrix: an innovative tool for diaphragmatic reconstruction in patients with large intra-abdominal tumors.

Am J Surg 2010 Jan 17;199(1):e12-6. Epub 2009 Oct 17.

Section of Surgical Oncology, Department of Surgery, Penn State College of Medicine, PO Box 850, 500 University Dr., H070, Hershey, PA 17033, USA.

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January 2010

A reduction in delayed gastric emptying by classic pancreaticoduodenectomy with an antecolic gastrojejunal anastomosis and a retrogastric omental patch.

J Gastrointest Surg 2009 Sep 23;13(9):1674-82. Epub 2009 Jun 23.

Liver, Pancreas and Foregut Unit, Department of Surgery, Penn State College of Medicine, Hershey, PA 17033-0850, USA.

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September 2009

Completion pancreatectomy for treatment of a Clostridium perfringens pancreatic infection.

Arch Surg 2009 Apr;144(4):368-70

Department of Surgery, Penn State Milton S. Hershey Medical Center, Hershey, PA 17033-0850, USA.

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April 2009

Reduction of surgical site infections by use of pulsatile lavage irrigation after prolonged intra-abdominal surgical procedures.

Am J Surg 2009 Sep 2;198(3):381-6. Epub 2009 Apr 2.

Section of Surgical Oncology, Department of Surgery, Milton S Hershey Medical Center, Hershey, PA 17033-0850, USA.

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September 2009

Pancreaticoduodenectomy in patients with a history of Roux-en Y gastric bypass surgery.

JOP 2009 Mar 9;10(2):169-73. Epub 2009 Mar 9.

Department of Surgery, University Hospitals, Case Medical Center, Cleveland, OH, USA.

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March 2009

Optimizing imatinib mesylate treatment in gastrointestinal stromal tumors.

Gastrointest Cancer Res 2008 Sep;2(5):245-50

Department of Medicine, Hematology/Oncology Division, Penn State University, Hershey Medical Center, Hershey, PA.

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September 2008

Early management of traumatic pancreatic transection by spleen-preserving laparoscopic distal pancreatectomy.

J Pediatr Surg 2009 Feb;44(2):455-8

University Hospitals, Case Medical Center, Cleveland, OH 44106, USA.

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February 2009

Additional organ resection combined with pancreaticoduodenectomy does not increase postoperative morbidity and mortality.

J Gastrointest Surg 2009 May 7;13(5):915-21. Epub 2009 Feb 7.

Section of Surgical Oncology, Department of Surgery, Penn State Milton S. Hershey Medical Center, Penn State College of Medicine, H070, 500 University Drive, P.O. Box 850, Hershey, PA 17033-0850, USA.

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May 2009

Diagnosis and management of retroperitoneal ancient schwannomas.

World J Surg Oncol 2009 Feb 2;7:12. Epub 2009 Feb 2.

Department of Surgery, University Hospitals, Case Medical Center, Cleveland, OH, USA.

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February 2009

Survival outcomes of patients with colorectal liver metastases following hepatic resection or ablation in the era of effective chemotherapy.

Ann Surg Oncol 2009 Jul 27;16(7):1860-7. Epub 2008 Nov 27.

Department of Surgery, Program for Liver, Pancreas and Foregut Tumors, Penn State College of Medicine, Hershey, PA 17033-0850, USA.

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July 2009

Combined right nephrectomy and pancreaticoduodenectomy. Indications and outcomes.

JOP 2008 Jul 10;9(4):449-55. Epub 2008 Jul 10.

Department of Surgery, Penn State Milton S. Hershey Medical Center, Penn State College of Medicine. Hershey, PA 17033-0850, USA.

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July 2008

Surgical outcomes of patients with gastrointestinal stromal tumors in the era of targeted drug therapy.

J Gastrointest Surg 2008 Nov 11;12(11):2023-31. Epub 2008 Jun 11.

Department of Surgery, Penn State College of Medicine, Penn State Milton S. Hershey Medical Center, H070, 500 University Drive, P.O. Box 850, Hershey, PA 17033-0850, USA.

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November 2008