Publications by authors named "Mehdi Touat"

32Publications

Efficacy of a Second Brain Biopsy for Intracranial Lesions after Initial Negativity.

J Clin Neurol 2020 Oct;16(4):659-667

Department of Neurosurgery, La Pitié-Salpêtrière-Charles Foix University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.

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http://dx.doi.org/10.3988/jcn.2020.16.4.659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542000PMC
October 2020

Is chemotherapy alone an option as initial treatment for low-grade oligodendrogliomas?

Curr Opin Neurol 2020 Dec;33(6):707-715

Department of Neuro-Oncology, University and City of Health and Science Hospital of Turin, Turin, Italy.

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http://dx.doi.org/10.1097/WCO.0000000000000866DOI Listing
December 2020

Mechanisms and therapeutic implications of hypermutation in gliomas.

Nature 2020 04 15;580(7804):517-523. Epub 2020 Apr 15.

Department of Oncologic Pathology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41586-020-2209-9DOI Listing
April 2020

5-Azacitidine in patients with IDH1/2-mutant recurrent glioma.

Neuro Oncol 2020 08;22(8):1226-1228

Sorbonne University, Institute of the Brain and Spinal Cord, Department of Neurosurgery, University Hospitals of Pitié Salpêtrière‒Charles Foix, Neurology Service 2-Mazarin, Paris, France.

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http://dx.doi.org/10.1093/neuonc/noaa074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594550PMC
August 2020

PD1 pathway in immune-mediated myopathies: Pathogenesis of dysfunctional T cells revisited.

Neurol Neuroimmunol Neuroinflamm 2019 05 10;6(3):e558. Epub 2019 Apr 10.

Department of Neurology (S.K., W.B., M.E.) and Department of Neuropathology (C.P., N.F., H.R., R.M., V.M., H.-H.G., W.S.), Charité-Universitätsmedizin, Berlin, Germany; Department of Internal Medicine and Clinical Immunology (Y.A., O.B.), Assistance Public-Hôpitaux de Paris, Sorbonne-Université, INSERM, UMR974, Pitié-Salpêtrière University Hospital; Unité de Pathologie Neuromusculaire (S.L.-L.), Centre de Référence Paris-Est, Groupe Hospitalier Pitié-Salpêtrière; Service de Neurologie 2-Mazarin (M.T.), Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, APHP; OncoNeuroTox Group (M.T.), Center for Patients with Neurological Complications of Oncologic Treatments, Hôpitaux Universitaires Pitié-Salpetrière-Charles Foix et Hôpital Percy; Inserm U 1127 (M.T.), CNRS UMR 7225, Institut du Cerveau et de la Moelle épinière, ICM, Université Pierre-et-Marie-Curie, Sorbonne Université, Paris, France; Leibniz ScienceCampus Chronic Inflammation (H.R., R.M., W.S.); Center for Stroke Research Berlin (M.E.), Charité-Universitätsmedizin, Berlin; German Centre for Cardiovascular Research (DZHK) (M.E.); and German Center for Neurodegenerative Diseases (DZNE) (M.E.).

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http://dx.doi.org/10.1212/NXI.0000000000000558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467687PMC
May 2019

A Payer Perspective of the Hospital Inpatient Additional Care Costs of Antimicrobial Resistance in France: A Matched Case-Control Study.

Appl Health Econ Health Policy 2019 06;17(3):381-389

Biostatistics, Biomathematics, Pharmacoepidemiology and Infectious Diseases (B2PHI), Inserm, UVSQ, Institut Pasteur, Paris-Saclay University, 2, avenue de la Source de la Bièvre, 78180, Montigny-Le-Bretonneux, France.

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http://link.springer.com/10.1007/s40258-018-0451-1
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http://dx.doi.org/10.1007/s40258-018-0451-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535148PMC
June 2019

Microfluidic active loading of single cells enables analysis of complex clinical specimens.

Nat Commun 2018 11 14;9(1):4784. Epub 2018 Nov 14.

Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.

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http://www.nature.com/articles/s41467-018-07283-x
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http://dx.doi.org/10.1038/s41467-018-07283-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235965PMC
November 2018

BRAF Inhibition in -Mutant Gliomas: Results From the VE-BASKET Study.

J Clin Oncol 2018 12 23;36(35):3477-3484. Epub 2018 Oct 23.

Thomas Kaley, Lisa M. DeAngelis, Jose Baselga, and David M. Hyman, Memorial Sloan Kettering Cancer Center; Thomas Kaley, Lisa M. DeAngelis, Jose Baselga, and David M. Hyman, Weill Cornell Medical College, New York; Igor Puzanov, Roswell Park Cancer Institute, Buffalo, NY; Mehdi Touat and Antoine Hollebecque, Institut Gustave Roussy, Villejuif; Franck Bielle, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Pitié Salpêtrière-Charles Foix, Paris; Florence Joly, Centre François Baclesse, Caen; Jean-Yves Blay, Centre Léon Bérard, Lyon, France; Vivek Subbiah, MD Anderson Cancer Center, Houston, TX; Jordi Rodon, Vall d'Hebron University Hospital, Barcelona, Spain; A. Craig Lockhart, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL; Vicki Keedy, Vanderbilt University Medical Center, Nashville, TN; Ralf-Dieter Hofheinz, Universitätsmedizin Mannheim, Mannheim; Jurgen Wolf, Universitätsklinikum Köln, Cologne, Germany; Ian Chau, The Royal Marsden National Health Service Foundation Trust, London, United Kingdom; Noopur S. Raje, Massachusetts General Hospital, Boston, MA; Martina Makrutzki, F Hoffmann-La Roche, Basel, Switzerland; Todd Riehl, Genentech, South San Francisco, CA; and Bethany Pitcher, F Hoffmann-La Roche, Mississauga, Ontario, Canada.

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http://ascopubs.org/doi/10.1200/JCO.2018.78.9990
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http://dx.doi.org/10.1200/JCO.2018.78.9990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286161PMC
December 2018

Vemurafenib and cobimetinib overcome resistance to vemurafenib in -mutant ganglioglioma.

Neurology 2018 09 17;91(11):523-525. Epub 2018 Aug 17.

From Sorbonne Université (M.T., A.I., M.S., A.L.D.S.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Service de Neurologie 2-Mazarin, Paris, France; Department of Oncologic Pathology (M.T., K.L.L.), Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA; Department of Neuroradiology (J.G., S.C.A.), Pharmacy Department (K.S.), and Departments of Neurosurgery (S.A.), Pathology (C.V.), and Neurology (A.L.D.S.), Hôpital Foch, Suresnes; Department of Radiology (J.S.), Fondation Ophtalmologique Adolphe de Rothschild, Paris; Département de Génétique (G.P., A.-P.G.-R., P.L.-P.), and Service de Biochimie, UF de Pharmacogénétique et Oncologie Moléculaire (H.B.), Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges-Pompidou, Paris; INSERM (G.P., H.B., P.L.-P.), UMR S 1147, Paris; Drug Development Department (A.H.), Gustave Roussy, Université Paris-Saclay, Villejuif; INSERM (A.-P.G.-R.), UMR970, Paris-Cardiovascular Research Center, Equipe Labellisée par la Ligue contre le Cancer, Paris; and Université Paris Descartes (H.B., A.-P.G.-R., P.L.-P.), Sorbonne Paris Cité, Faculté de Médecine, Paris, France.

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http://dx.doi.org/10.1212/WNL.0000000000006171DOI Listing
September 2018

Immune checkpoint inhibitor-related myositis and myocarditis in patients with cancer.

Neurology 2018 09 8;91(10):e985-e994. Epub 2018 Aug 8.

From Sorbonne Université (M.T., D.P.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM, APHP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Service de Neurologie 2-Mazarin; OncoNeuroTox Group (M.T., T.M., N.W., T.L., D.P.), Center for Patients With Neurological Complications of Oncologic Treatments, Hôpitaux Universitaires Pitié-Salpetrière-Charles Foix et Hôpital Percy, Paris, France; Department of Oncologic Pathology (M.T.), Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA; Service de Neuropathologie Raymond Escourolle (T.M., S.L.-L.), Départment de Neurophysiologie Clinique (T.M., T.L., S.L.-L.), Département de Médecine Interne et Immunologie Clinique (B.H., Y.A., O.B.), and Centre de Référence de Pathologie Neuromusculaire Paris-Est (B.H., A.B., Y.A., O.B., S.L.-L.), APHP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Paris, France; Charité-Universitatsmedizin Berlin Klinik fur Neurologie mit Experimenteller Neurologie (S.K.), Experimentelle Neurologie; Centrum fur Schlaganfallforschung Berlin (S.K.), Germany; Service de Réanimation Médicale (O.B.H.S.), Service de Médecine Interne (T.-A.S.), and Département de Dermatologie (N.K.), Hôpital Cochin, APHP, Hôpitaux Universitaires Paris Centre; Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris) (B.H.), Sorbonne Universités; Service d'Explorations Fonctionnelles (K.A.), APHP, Hôpital Ambroise Paré, Boulogne-Billancourt; Service de Pneumologie (C.L.) and Service d'Anatomie Pathologique (J.-F.B.), Centre Hospitalier Chartres-Louis-Pasteur, Le-Coudray; Service de Dermatologie (P.L.), APHP, Hôpital Saint Louis; Service de Pneumologie et Oncologie Thoracique (J.C.), Centre de Compétences pour les Maladies Pulmonaires Rares, APHP, Hôpital Tenon, Sorbonne Universités; Sorbonne Université (N.W.), Brain Liver Pitié-Salpêtrière (BLIPS) Study Group, INSERM, Centre de Recherche Saint-Antoine, APHP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Département de Neurologie, Unité de réanimation neurologique; Inserm UMR974 (Y.A., O.B.), Centre de recherche en myologie, Université Pierre-et-Marie-Curie, Sorbonnes Universités, Paris, France; and Department of Neuropathology (W.S.), Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Germany.

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http://dx.doi.org/10.1212/WNL.0000000000006124DOI Listing
September 2018

actionable mutations, molecular specificities, and outcome of adult midline gliomas.

Neurology 2018 06 4;90(23):e2086-e2094. Epub 2018 May 4.

From Sorbonne Université (A.P., G.B., F.B., M.T., E.T., S.M., Y.S., A.I., K.H.-X., J.-Y.D., K.M., A.L.D.S., M.S.), UPMC Univ Paris 06 UMR S 1127, Inserm U 1127, CNRS UMR 7225, ICM; Service de Neurologie 2 (A.P., G.B., M.T., A.I., K.H.-X., J.-Y.D., M.S.) and Laboratoire R Escourolle 2 (F.B., K.M.), AP-HP, Hôpital de la Pitié-Salpêtrière, Paris, France; Neuroscience Consortium (A.P., G.B.), Monza Policlinico and Pavia Mondino, University of Pavia, Italy; Centre d'Imagerie (J.S.), Fondation A de Rothschild; Laboratoire d'Anatomie Pathologique (M.P.), AP-HP, Hôpital Lariboisière, Paris, France; Pathology Unit (E.T.), AOU "Maggiore della Carità" di Novara, Italy; Onconeurotek Tumour Bank (J.-Y.D., K.M., M.S.), GH Pitié-Salpêtrière; and Department of Neurology (A.L.D.S.), Foch Hospital, Suresnes, Paris, France.

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http://dx.doi.org/10.1212/WNL.0000000000005658DOI Listing
June 2018

Neurological toxicities associated with immune-checkpoint inhibitors.

Curr Opin Neurol 2017 Dec;30(6):659-668

aInserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM bAP-HP, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Service de Neurologie 2-Mazarin cOncoNeuroTox Group, Center for Patients with Neurological Complications of Oncologic Treatments, Hôpitaux Universitaires Pitié-Salpetrière-Charles Foix et Hôpital d'Instruction des Armées Percy, Paris, France dDepartment of Oncologic Pathology, Dana-Farber/Brigham and Women's Cancer Center eDepartment of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA fService de neurologie, Hôpital d'Instruction des Armées Percy, Service de Santé des Armées, Clamart, France gUMR MD4 8257 CNRS, Université Paris Descartes, SSA, Paris, France, Ecole du Val-de-Grâce, Service de santé des armées, Paris, France.

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http://dx.doi.org/10.1097/WCO.0000000000000503DOI Listing
December 2017

Acute Frontal Lobe Dysfunction Following Prefrontal Low-Frequency Repetitive Transcranial Magnetic Stimulation in a Patient with Treatment-Resistant Depression.

Front Psychiatry 2017 30;8:96. Epub 2017 May 30.

FrontLab, INSERM U1127, CNRS UMR7225, IHU Translational Neurosciences, Institut du Cerveau et de la Moelle Epinière (ICM), Paris, France.

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http://dx.doi.org/10.3389/fpsyt.2017.00096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447704PMC
May 2017

IDH1 and IDH2 mutations as novel therapeutic targets: current perspectives.

J Blood Med 2016 2;7:171-80. Epub 2016 Sep 2.

Gustave Roussy, Université Paris-Saclay, Service d'Hématologie Clinique; INSERM U1170, Gustave Roussy, Université Paris-Saclay, Villejuif; Faculté de médecine Paris-Sud, Kremlin-Bicêtre.

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http://dx.doi.org/10.2147/JBM.S70716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015873PMC
September 2016

Radiation plus Chemotherapy in Low-Grade Glioma.

N Engl J Med 2016 08;375(5):489-90

Hôpital Universitaire Pitié-Salpêtrière, Paris, France

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http://dx.doi.org/10.1056/NEJMc1605897DOI Listing
August 2016

Recurrence of Cerebral Amyloid Angiopathy-Related Inflammation: A Report of Two Cases from the iCAβ International Network.

J Alzheimers Dis 2015 ;46(4):1071-7

Department of Surgery and Translational Medicine, Milan Center for Neuroscience (NeuroMi), University of Milano-Bicocca, Monza, Italy.

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http://dx.doi.org/10.3233/JAD-150070DOI Listing
June 2016

Emerging circulating biomarkers in glioblastoma: promises and challenges.

Expert Rev Mol Diagn 2015 ;15(10):1311-23

c 3 AP-HP, Hôpital Universitaire la Pitié Salpêtrière, Service de Neurologie 2-Mazarin, F-75013, Paris, France.

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http://dx.doi.org/10.1586/14737159.2015.1087315DOI Listing
June 2016

Targeting FGFR Signaling in Cancer.

Clin Cancer Res 2015 Jun;21(12):2684-94

Drug Development Department (DITEP), Gustave Roussy, Villejuif, France. University Paris Sud, INSERM U981, Predictive Biomarkers and New Therapeutic Strategies in Oncology, Gustave Roussy, Villejuif, France.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2329DOI Listing
June 2015

Systematic review and meta-analysis of phase I/II targeted therapy combined with radiotherapy in patients with glioblastoma multiforme: quality of report, toxicity, and survival.

J Neurooncol 2015 Jun 15;123(2):307-14. Epub 2015 May 15.

Department of Radiation Oncology, INSERM 1030 "Molecular Radiotherapy", Gustave Roussy, Gustave Roussy Cancer Campus, 114 Rue Édouard Vaillant, 94805, Villejuif Cedex, France.

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http://dx.doi.org/10.1007/s11060-015-1802-5DOI Listing
June 2015

Successful treatment of multiple intracranial meningiomas with the antiprogesterone receptor agent mifepristone (RU486).

Acta Neurochir (Wien) 2014 Oct 31;156(10):1831-5. Epub 2014 Jul 31.

AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Service de Neurologie 2, Paris, 75013, France.

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http://link.springer.com/10.1007/s00701-014-2188-4
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http://dx.doi.org/10.1007/s00701-014-2188-4DOI Listing
October 2014