Mehdi Totonchi

Mehdi Totonchi

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Mehdi Totonchi

Mehdi Totonchi

Publications by authors named "Mehdi Totonchi"

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Rare case of an oligospermic male with 46,XX/46,XY tetragametic chimerism.

Andrologia 2019 Aug 17;51(7):e13290. Epub 2019 Apr 17.

Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.

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http://dx.doi.org/10.1111/and.13290DOI Listing
August 2019

Histone Modification Marks Strongly Regulate CDH1 Promoter in Prostospheres as A Model of Prostate Cancer Stem Like Cells.

Cell J 2019 Jul 20;21(2):124-134. Epub 2019 Feb 20.

Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran. Electronic

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http://dx.doi.org/10.22074/cellj.2019.5702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397603PMC
July 2019

Effect of Prepubertal Exposure to CdCl2 on the Liver, Hematological, and Biochemical Parameters in Female Rats; an Experimental Study.

Biol Trace Elem Res 2019 Jul 9. Epub 2019 Jul 9.

Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.

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http://dx.doi.org/10.1007/s12011-019-01800-9DOI Listing
July 2019

Epigenetic reprogramming of primary pancreatic cancer cells counteracts their in vivo tumourigenicity.

Oncogene 2019 Jul 15. Epub 2019 Jul 15.

Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, 28029, Madrid, Spain.

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http://dx.doi.org/10.1038/s41388-019-0871-xDOI Listing
July 2019

Identification of a missense variant in CLDN2 in obstructive azoospermia.

J Hum Genet 2019 Jul 18. Epub 2019 Jul 18.

Department of Genetics at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.

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http://dx.doi.org/10.1038/s10038-019-0642-0DOI Listing
July 2019

Programming of ES cells and reprogramming of fibroblasts into renal lineage-like cells.

Exp Cell Res 2019 Jun 11;379(2):225-234. Epub 2019 Apr 11.

Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2019.04.011DOI Listing
June 2019

ADCY10 frameshift variant leading to severe recessive asthenozoospermia and segregating with absorptive hypercalciuria.

Hum Reprod 2019 Jun;34(6):1155-1164

Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.

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http://dx.doi.org/10.1093/humrep/dez048DOI Listing
June 2019

Identification of the Molecular Events Involved in the Development of Prefrontal Cortex Through the Analysis of RNA-Seq Data From BrainSpan.

ASN Neuro 2019 Jan-Dec;11:1759091419854627

1 Department of Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.

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http://dx.doi.org/10.1177/1759091419854627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582306PMC
June 2019

Identification of a homozygous GFPT2 variant in a family with asthenozoospermia.

Gene 2019 May 5;699:16-23. Epub 2019 Mar 5.

Department of Genetics at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03781119193019
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http://dx.doi.org/10.1016/j.gene.2019.02.060DOI Listing
May 2019

In vivo conversion of astrocytes to oligodendrocyte lineage cells in adult mice demyelinated brains by Sox2.

Mult Scler Relat Disord 2019 Feb 2;28:263-272. Epub 2019 Jan 2.

Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, P.O.Box:14115-331, Tehran, Iran; Department of Brain and Cognitive Sciences, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2018.12.041DOI Listing
February 2019

Human Ovarian Theca-Derived Multipotent Stem Cells Have The Potential to Differentiate into Oocyte-Like Cells In Vitro.

Cell J 2019 Jan 1;20(4):527-536. Epub 2018 Aug 1.

Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran. Electronic Address:

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http://dx.doi.org/10.22074/cellj.2019.5651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099133PMC
January 2019

Establishment and characterization of human theca stem cells and their differentiation into theca progenitor cells.

J Cell Biochem 2018 Dec 21;119(12):9853-9865. Epub 2018 Aug 21.

Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.

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http://dx.doi.org/10.1002/jcb.27306DOI Listing
December 2018

Genomic integrity of ground-state pluripotency.

J Cell Biochem 2018 Dec 1;119(12):9781-9789. Epub 2018 Sep 1.

Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.

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http://doi.wiley.com/10.1002/jcb.27296
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http://dx.doi.org/10.1002/jcb.27296DOI Listing
December 2018

Temporal Gene Expression and DNA Methylation during Embryonic Stem Cell Derivation.

Cell J 2018 Oct 15;20(3):361-368. Epub 2018 May 15.

Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.

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http://dx.doi.org/10.22074/cellj.2018.5482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004995PMC
October 2018

Attitude of A Sample of Iranian Researchers toward The Future of Stem Cell Research.

Cell J 2018 Oct 15;20(3):443-448. Epub 2018 May 15.

Department of Epidemiology and Reproductive Health, Reproductive Epidemiology Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.

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http://celljournal.org/journal/article/abstract/5388
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http://dx.doi.org/10.22074/cellj.2018.5388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005005PMC
October 2018

Gene alterations and expression spectrum of SPATA33 in nonobstructive azoospermic Iranian men.

Mol Reprod Dev 2018 10 7;85(10):760-767. Epub 2018 Sep 7.

Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.

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http://doi.wiley.com/10.1002/mrd.23051
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http://dx.doi.org/10.1002/mrd.23051DOI Listing
October 2018

Expression analysis of genes encoding and in testis tissues of men with non-obstructive azoospermia.

JBRA Assist Reprod 2018 Sep 1;22(3):185-192. Epub 2018 Sep 1.

Department of Andrology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.

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http://www.gnresearch.org/doi/10.5935/1518-0557.20180030
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http://dx.doi.org/10.5935/1518-0557.20180030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106636PMC
September 2018

Long term culture and differentiation of endothelial progenitor like cells from rat adipose derived stem cells.

Cytotechnology 2018 Feb 20;70(1):397-413. Epub 2017 Dec 20.

Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Islamic Republic of Iran.

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http://dx.doi.org/10.1007/s10616-017-0155-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809669PMC
February 2018

The Impact of Genetic Variation and Gene Expression Level of The Follicle-Stimulating Hormone Receptor on Ovarian Reserve.

Cell J 2018 Jan 4;19(4):620-626. Epub 2017 Nov 4.

Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, IranElectronic address:

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http://celljournal.org/journal/article/abstract/4183
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http://dx.doi.org/10.22074/cellj.2018.4183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672101PMC
January 2018

Slow freezing versus vitrification technique for human ovarian tissue cryopreservation: An evaluation of histological changes, WNT signaling pathway and apoptotic genes expression.

Cryobiology 2017 12 4;79:29-36. Epub 2017 Oct 4.

Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran; Department of Anatomy, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.cryobiol.2017.09.007DOI Listing
December 2017

Blockage of the Epithelial-to-Mesenchymal Transition Is Required for Embryonic Stem Cell Derivation.

Stem Cell Reports 2017 10 14;9(4):1275-1290. Epub 2017 Sep 14.

Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran; Department of Developmental Biology, University of Science and Culture, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639184PMC
October 2017

FMR1 premutation: not only important in premature ovarian failure but also in diminished ovarian reserve.

Hum Fertil (Camb) 2017 Jun 23;20(2):120-125. Epub 2016 Nov 23.

a Department of Genetics , Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR , Tehran , Iran.

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http://dx.doi.org/10.1080/14647273.2016.1255356DOI Listing
June 2017

Thrombophilic genes alterations as risk factor for recurrent pregnancy loss.

J Matern Fetal Neonatal Med 2016 2;29(8):1269-73. Epub 2015 Jul 2.

b Department of Genetics at Reproductive Biomedicine Research Center , Royan Institute for Reproductive Biomedicine , ACECR , Tehran , Iran.

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http://dx.doi.org/10.3109/14767058.2015.1044431DOI Listing
October 2016

Association of MOV10L1 gene polymorphisms and male infertility in azoospermic men with complete maturation arrest.

J Assist Reprod Genet 2014 Jul 10;31(7):865-71. Epub 2014 May 10.

Department of Genetics at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, P.O. Box 19395-4644, Tehran, Iran.

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http://dx.doi.org/10.1007/s10815-014-0240-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096888PMC
July 2014

Delineating the association between isodicentric chromosome Y and infertility: a retrospective study.

Fertil Steril 2014 Apr 4;101(4):1091-6. Epub 2014 Feb 4.

Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, The Academic Center for Education, Culture and Research (ACECR), Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.fertnstert.2013.12.048DOI Listing
April 2014

Inhibition of TGFβ signaling promotes ground state pluripotency.

Stem Cell Rev 2014 Feb;10(1):16-30

Department of Stem Cells and Developmental Biology at Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, PO Box 19395-4644, Tehran, Iran.

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http://dx.doi.org/10.1007/s12015-013-9473-0DOI Listing
February 2014

Signaling roadmap modulating naive and primed pluripotency.

Stem Cells Dev 2014 Feb 27;23(3):193-208. Epub 2013 Nov 27.

1 Department of Stem Cells and Developmental Biology at Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology , ACECR, Tehran, Iran .

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http://dx.doi.org/10.1089/scd.2013.0368DOI Listing
February 2014

Quantitative expression of developmental genes, Pou5f1 (Oct4) and Mest (Peg1), in vitrified mouse embryos.

Iran J Reprod Med 2013 Sep;11(9):733-40

Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941331PMC
September 2013

Disease-corrected hepatocyte-like cells from familial hypercholesterolemia-induced pluripotent stem cells.

Mol Biotechnol 2013 Jul;54(3):863-73

Department of Molecular Systems Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.

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http://dx.doi.org/10.1007/s12033-012-9635-3DOI Listing
July 2013

Clinical data for 185 infertile Iranian men with Y-chromosome microdeletion.

J Assist Reprod Genet 2012 Aug 31;29(8):847-53. Epub 2012 May 31.

Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.

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http://dx.doi.org/10.1007/s10815-012-9798-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430778PMC
August 2012

Simultaneous suppression of TGF-β and ERK signaling contributes to the highly efficient and reproducible generation of mouse embryonic stem cells from previously considered refractory and non-permissive strains.

Stem Cell Rev 2012 Jun;8(2):472-81

Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, PO Box 19395-4644, Tehran, Iran.

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http://dx.doi.org/10.1007/s12015-011-9306-yDOI Listing
June 2012

Effects of amifostine in combination with cyclophosphamide on female reproductive system.

Reprod Sci 2012 May 19;19(5):539-46. Epub 2012 Jan 19.

Department of Reproductive Genetics, Reproductive Biomedicine Research Center, Royan Institute, ACECR, Tehran, Iran.

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http://dx.doi.org/10.1177/1933719111426599DOI Listing
May 2012

Concise review: alchemy of biology: generating desired cell types from abundant and accessible cells.

Stem Cells 2011 Dec;29(12):1933-41

Department of Stem Cells and Developmental Biology, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.

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http://dx.doi.org/10.1002/stem.760DOI Listing
December 2011

Long-term maintenance of undifferentiated human embryonic and induced pluripotent stem cells in suspension.

Stem Cells Dev 2011 Nov 24;20(11):1911-23. Epub 2011 Feb 24.

Department of Stem Cells and Developmental Biology, Royan Institute for Stem Cell Biology and Technology, The Academic Center for Education, Culture and Research, Tehran, Iran.

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http://dx.doi.org/10.1089/scd.2010.0517DOI Listing
November 2011

Generation of liver disease-specific induced pluripotent stem cells along with efficient differentiation to functional hepatocyte-like cells.

Stem Cell Rev 2010 Dec;6(4):622-32

Department of Stem Cells and Developmental Biology, Royan Institute for Stem Cell Biology and Technology, ACECR, P.O. Box 19395-4644, Tehran, Iran.

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http://dx.doi.org/10.1007/s12015-010-9189-3DOI Listing
December 2010

Feeder- and serum-free establishment and expansion of human induced pluripotent stem cells.

Int J Dev Biol 2010 ;54(5):877-86

Department of Stem Cells and Developmental Biology, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.

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http://dx.doi.org/10.1387/ijdb.092903mtDOI Listing
August 2010

Derivation of new human embryonic stem cell lines from preimplantation genetic screening and diagnosis-analyzed embryos.

In Vitro Cell Dev Biol Anim 2010 Apr 23;46(3-4):395-402. Epub 2010 Feb 23.

Department of Stem Cells and Developmental Biology, Royan Institute for Stem Cell Biology and Technology, ACECR, P.O. Box 19395-4644, Tehran, Iran.

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http://link.springer.com/content/pdf/10.1007/s11626-010-9293
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http://link.springer.com/10.1007/s11626-010-9293-3
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http://dx.doi.org/10.1007/s11626-010-9293-3DOI Listing
April 2010

Human-induced pluripotent stem cells: derivation, propagation, and freezing in serum- and feeder layer-free culture conditions.

Methods Mol Biol 2010 ;584:425-43

Department of Stem Cells, Cell Science Research Center, Royan Institute, ACECR, Tehran, Iran.

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http://dx.doi.org/10.1007/978-1-60761-369-5_23DOI Listing
February 2010

Generation of human induced pluripotent stem cells from a Bombay individual: moving towards "universal-donor" red blood cells.

Biochem Biophys Res Commun 2010 Jan 11;391(1):329-34. Epub 2009 Nov 11.

Department of Stem Cells and Developmental Biology, Royan Institute for Stem Cell Biology and Technology, PO Box 19395-4644, ACECR, Tehran, Iran.

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http://dx.doi.org/10.1016/j.bbrc.2009.11.058DOI Listing
January 2010

A simple and efficient cryopreservation method for feeder-free dissociated human induced pluripotent stem cells and human embryonic stem cells.

Hum Reprod 2009 Oct 14;24(10):2468-76. Epub 2009 Jul 14.

Department of Stem Cells and Developmental Biology, Royan Institute for Stem Cell Biology and Technology, ACECR, PO Box 19395-4644, Tehran, Iran.

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http://dx.doi.org/10.1093/humrep/dep244DOI Listing
October 2009

De novo complex chromosomal rearrangement of 46, XY, t (3; 16; 8) (p26; q13; q21.2) in a non-obstructive azoospermic male.

J Appl Genet 2007 ;48(1):93-4

Department of Infertility Genetics, Infertility Clinic & Reproductive Biomedicine Research Center, Royan Institute, Tehran, Iran.

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http://dx.doi.org/10.1007/BF03194664DOI Listing
March 2007