Mehdi Shakibaei

Mehdi Shakibaei

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Mehdi Shakibaei

Publications by authors named "Mehdi Shakibaei"

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Evidence that TNF-β suppresses osteoblast differentiation of mesenchymal stem cells and resveratrol reverses it through modulation of NF-κB, Sirt1 and Runx2.

Cell Tissue Res 2020 Jul 6;381(1):83-98. Epub 2020 Mar 6.

Musculoskeletal Research Group and Tumour Biology, Chair of Vegetative Anatomy, Faculty of Medicine, Institute of Anatomy, Ludwig-Maximilian-University Munich, Pettenkoferstrasse 11, 80336, Munich, Germany.

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http://dx.doi.org/10.1007/s00441-020-03188-8DOI Listing
July 2020

Herbal Remedies as Potential in Cartilage Tissue Engineering: An Overview of New Therapeutic Approaches and Strategies.

Molecules 2020 Jul 6;25(13). Epub 2020 Jul 6.

Department of Anatomical Sciences, School of Medicine, Isfahan University of Medical Sciences, Isfahan 73461-81746, Iran.

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http://dx.doi.org/10.3390/molecules25133075DOI Listing
July 2020

Targeting NF-κB Signaling by Calebin A, a Compound of Turmeric, in Multicellular Tumor Microenvironment: Potential Role of Apoptosis Induction in CRC Cells.

Biomedicines 2020 Jul 22;8(8). Epub 2020 Jul 22.

Musculoskeletal Research Group and Tumor Biology, Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, Ludwig-Maximilian-University Munich, Pettenkoferstrasse 11, D-80336 Munich, Germany.

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http://dx.doi.org/10.3390/biomedicines8080236DOI Listing
July 2020

Flavonoids in Cancer Metastasis.

Cancers (Basel) 2020 Jun 8;12(6). Epub 2020 Jun 8.

Department of Medical Biology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 03601 Martin, Slovakia.

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http://dx.doi.org/10.3390/cancers12061498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352928PMC
June 2020

Neuronal aldosterone elicits a distinct genomic response in pain signaling molecules contributing to inflammatory pain.

J Neuroinflammation 2020 Jun 12;17(1):183. Epub 2020 Jun 12.

Department of Anaesthesiology and Intensive Care Medicine, Charité - University Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Campus Benjamin Franklin, Berlin, Germany.

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http://dx.doi.org/10.1186/s12974-020-01864-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291517PMC
June 2020

Organophosphorus Compounds and MAPK Signaling Pathways.

Int J Mol Sci 2020 Jun 15;21(12). Epub 2020 Jun 15.

Healthy Ageing Research Center, Neyshabur University of Medical Sciences, Neyshabur 9318614139, Iran.

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http://dx.doi.org/10.3390/ijms21124258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352539PMC
June 2020

Aldosterone Synthase in Peripheral Sensory Neurons Contributes to Mechanical Hypersensitivity during Local Inflammation in Rats.

Anesthesiology 2020 04;132(4):867-880

From the Department of Anaesthesiology and Intensive Care Medicine, Charite Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, Berlin, Germany (D.M.M., M. Shaqura, X.L., S.T., M. Schäfer, S.A.M.) Department of Zoology, Faculty of Science, Aswan University, Aswan, Egypt (D.M.M.) the Departments of Anatomy (M. Shakibaei) Anaesthesiology (A.B.), Ludwig Maximilian University of Munich, Munich, Germany.

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http://dx.doi.org/10.1097/ALN.0000000000003127DOI Listing
April 2020

Calebin A Potentiates the Effect of 5-FU and TNF-β (Lymphotoxin α) against Human Colorectal Cancer Cells: Potential Role of NF-κB.

Int J Mol Sci 2020 Mar 31;21(7). Epub 2020 Mar 31.

Musculoskeletal Research Group and Tumour Biology, Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, Ludwig-Maximilian-University Munich, Pettenkoferstrasse 11, D-80336 Munich, Germany.

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http://dx.doi.org/10.3390/ijms21072393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177530PMC
March 2020

The vital role of ATP citrate lyase in chronic diseases.

J Mol Med (Berl) 2020 01 19;98(1):71-95. Epub 2019 Dec 19.

Cancer Biology Laboratory & DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), Department of Biosciences & Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, 781039, India.

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http://dx.doi.org/10.1007/s00109-019-01863-0DOI Listing
January 2020

Evidence That Calebin A, a Component of Suppresses NF-B Mediated Proliferation, Invasion and Metastasis of Human Colorectal Cancer Induced by TNF-β (Lymphotoxin).

Nutrients 2019 Dec 1;11(12). Epub 2019 Dec 1.

Musculoskeletal Research Group and Tumor Biology, Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, Ludwig-Maximilian-University Munich, Pettenkoferstrasse 11, D-80336 Munich, Germany.

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http://dx.doi.org/10.3390/nu11122904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950382PMC
December 2019

An Update on Pharmacological Potential of Boswellic Acids against Chronic Diseases.

Int J Mol Sci 2019 Aug 22;20(17). Epub 2019 Aug 22.

Cancer Biology Laboratory and DBT-AIST International Centre for Translational and Environmental Research(DAICENTER), Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Assam 781039, India.

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http://dx.doi.org/10.3390/ijms20174101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747466PMC
August 2019

Induction of the Epithelial-to-Mesenchymal Transition of Human Colorectal Cancer by Human TNF-β (Lymphotoxin) and its Reversal by Resveratrol.

Nutrients 2019 Mar 26;11(3). Epub 2019 Mar 26.

Musculoskeletal Research Group and Tumor Biology, Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, Ludwig-Maximilian-University Munich, Pettenkoferstrasse 11, D-80336 Munich, Germany.

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http://dx.doi.org/10.3390/nu11030704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471988PMC
March 2019

Evidence that TNF-β induces proliferation in colorectal cancer cells and resveratrol can down-modulate it.

Exp Biol Med (Maywood) 2019 01 19;244(1):1-12. Epub 2019 Jan 19.

1 Musculoskeletal Research Group and Tumor Biology, Chair of Vegetative Anatomy, Faculty of Medicine, Ludwig-Maximilian-University Munich, Munich 80336, Germany.

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http://dx.doi.org/10.1177/1535370218824538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362535PMC
January 2019

Dietary nutraceuticals as backbone for bone health.

Biotechnol Adv 2018 11 27;36(6):1633-1648. Epub 2018 Mar 27.

Inflammation Research Center, San Diego, CA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S07349750183006
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http://dx.doi.org/10.1016/j.biotechadv.2018.03.014DOI Listing
November 2018

Resveratrol Chemosensitizes TNF-β-Induced Survival of 5-FU-Treated Colorectal Cancer Cells.

Nutrients 2018 Jul 12;10(7). Epub 2018 Jul 12.

Musculoskeletal Research Group and Tumour Biology, Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, Ludwig-Maximilian-University Munich, Pettenkoferstrasse 11, D-80336 Munich, Germany.

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http://www.mdpi.com/2072-6643/10/7/888
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http://dx.doi.org/10.3390/nu10070888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073304PMC
July 2018

Histopathological Changes in the Kidney following Congestive Heart Failure by Volume Overload in Rats.

Oxid Med Cell Longev 2017 31;2017:6894040. Epub 2017 Jul 31.

Department of Anaesthesiology and Intensive Care Medicine, Charité University Berlin, Campus Virchow Klinikum and Campus Charité Mitte, Berlin, Germany.

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http://dx.doi.org/10.1155/2017/6894040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555028PMC
April 2018

Accessibility of axonal G protein coupled mu-opioid receptors requires conceptual changes of axonal membrane targeting for pain modulation.

J Control Release 2017 Dec 17;268:352-363. Epub 2017 Oct 17.

Dep. of Anaesthesiology and Intensive Care Medicine, Charité University Berlin, Campus Virchow Klinikum and Campus Charite Mitte, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2017.10.016DOI Listing
December 2017

Resveratrol downregulates inflammatory pathway activated by lymphotoxin α (TNF-β) in articular chondrocytes: Comparison with TNF-α.

PLoS One 2017 2;12(11):e0186993. Epub 2017 Nov 2.

Musculoskeletal Research Group and Tumour Biology, Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, LMU Munich, Pettenkoferstrasse 11, Munich, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186993PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667866PMC
December 2017

Pathological alterations in liver injury following congestive heart failure induced by volume overload in rats.

PLoS One 2017 21;12(9):e0184161. Epub 2017 Sep 21.

Department of Anaesthesiology and Intensive Care Medicine, Charité University Berlin, Campus Virchow Klinikum and Campus Charité Mitte, Berlin, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0184161PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608213PMC
October 2017

Resveratrol Regulates Colorectal Cancer Cell Invasion by Modulation of Focal Adhesion Molecules.

Nutrients 2017 Sep 27;9(10). Epub 2017 Sep 27.

Musculoskeletal Research Group and Tumour Biology, Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, LMU Munich, Pettenkoferstrasse 11, D-80336 Munich, Germany.

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http://dx.doi.org/10.3390/nu9101073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691690PMC
September 2017

Tenomodulin is Required for Tendon Endurance Running and Collagen I Fibril Adaptation to Mechanical Load.

EBioMedicine 2017 Jun 5;20:240-254. Epub 2017 May 5.

Experimental Surgery and Regenerative Medicine, Department of Surgery, Ludwig-Maximilians-University (LMU), 80336 Munich, Germany; Experimental Trauma Surgery, Department of Trauma Surgery, University Regensburg Medical Centre, 93053 Regensburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478207PMC
June 2017

Membrane-bound glucocorticoid receptors on distinct nociceptive neurons as potential targets for pain control through rapid non-genomic effects.

Neuropharmacology 2016 12 21;111:1-13. Epub 2016 Aug 21.

Department of Anaesthesiology and Intensive Care Medicine, Charité University Berlin, Campus Virchow Klinikum and Campus Charité Mitte, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2016.08.019DOI Listing
December 2016

Evidence for MOR on cell membrane, sarcoplasmatic reticulum and mitochondria in left ventricular myocardium in rats.

Heart Vessels 2016 Aug 19;31(8):1380-8. Epub 2015 Dec 19.

Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.

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http://dx.doi.org/10.1007/s00380-015-0784-8DOI Listing
August 2016

Protein kinase C-mediated mu-opioid receptor phosphorylation and desensitization in rats, and its prevention during early diabetes.

Pain 2016 Apr;157(4):910-21

aDepartment of Anaesthesiology and Intensive Care Medicine, Charité University Berlin, Campus Virchow Klinikum and Campus Charité Mitte, Berlin, Germany bDepartment of Anatomy, Ludwig Maximilian University Munich, Munich, Germany cInstitute of Pharmacology and Toxicology, Jena University Hospital, Friedrich Schiller University, Jena, Germany dDepartment of Internal Medicine, Paulinenkrankenhaus, Berlin, Germany.

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http://pdfs.journals.lww.com/pain/2016/04000/Protein_kinase_
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http://dx.doi.org/10.1097/j.pain.0000000000000459DOI Listing
April 2016

Sirt1 Is Required for Resveratrol-Mediated Chemopreventive Effects in Colorectal Cancer Cells.

Nutrients 2016 Mar 5;8(3):145. Epub 2016 Mar 5.

Institute of Anatomy, Ludwig-Maximilian-University Munich, Pettenkoferstrasse 11, Munich D-80336, Germany.

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http://dx.doi.org/10.3390/nu8030145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808874PMC
March 2016

Cellular localization and adaptive changes of the cardiac delta opioid receptor system in an experimental model of heart failure in rats.

Heart Vessels 2016 Feb 1;31(2):241-50. Epub 2015 Jan 1.

Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow Klinikum, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.

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http://dx.doi.org/10.1007/s00380-014-0620-6DOI Listing
February 2016

Upregulation of the kappa opioidergic system in left ventricular rat myocardium in response to volume overload: Adaptive changes of the cardiac kappa opioid system in heart failure.

Pharmacol Res 2015 Dec 10;102:33-41. Epub 2015 Sep 10.

Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow-Klinikum, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.

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http://dx.doi.org/10.1016/j.phrs.2015.09.005DOI Listing
December 2015

Resveratrol induces chemosensitization to 5-fluorouracil through up-regulation of intercellular junctions, Epithelial-to-mesenchymal transition and apoptosis in colorectal cancer.

Biochem Pharmacol 2015 Nov 24;98(1):51-68. Epub 2015 Aug 24.

Institute of Anatomy, Ludwig-Maximilian-University Munich, Pettenkoferstrasse 11, D-80336 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2015.08.105DOI Listing
November 2015

Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint health.

Int J Mol Sci 2012 30;13(4):4202-32. Epub 2012 Mar 30.

Musculoskeletal Research Group, School of Veterinary Medicine and Science, Faculty of Medicine and Health Sciences, The University of Nottingham, Sutton Bonington, LE12 5RD, UK.

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http://dx.doi.org/10.3390/ijms13044202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344210PMC
August 2015

Novel Evidence for Curcumin and Boswellic Acid-Induced Chemoprevention through Regulation of miR-34a and miR-27a in Colorectal Cancer.

Cancer Prev Res (Phila) 2015 May 23;8(5):431-43. Epub 2015 Feb 23.

Center for Gastrointestinal Cancer Research; Center for Epigenetics, Cancer Prevention and Cancer Genomics, Baylor Research Institute and Charles A Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas.

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http://cancerpreventionresearch.aacrjournals.org/content/ear
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http://cancerpreventionresearch.aacrjournals.org/cgi/doi/10.
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http://dx.doi.org/10.1158/1940-6207.CAPR-14-0354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417447PMC
May 2015

Curcumin potentiates antitumor activity of 5-fluorouracil in a 3D alginate tumor microenvironment of colorectal cancer.

BMC Cancer 2015 Apr 10;15:250. Epub 2015 Apr 10.

Institute of Anatomy, Ludwig-Maximilian-University Munich, Pettenkoferstrasse 11, D-80336, Munich, Germany.

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http://dx.doi.org/10.1186/s12885-015-1291-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406109PMC
April 2015

Curcumin mediates chemosensitization to 5-fluorouracil through miRNA-induced suppression of epithelial-to-mesenchymal transition in chemoresistant colorectal cancer.

Carcinogenesis 2015 Mar 4;36(3):355-67. Epub 2015 Feb 4.

Center for Gastrointestinal Research, and Center for Epigenetics, Cancer Prevention and Cancer Genomics, Baylor Research Institute and Sammons Cancer Center, Baylor University Medical Center, 3500 Gaston Avenue, Suite H-250, Dallas, TX 75246, USA, Department of Ecology and Evolution and Department of Mathematics, University of California, Irvine, CA, USA and Institute of Anatomy, Ludwig-Maximilian University, Munich, Germany

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http://dx.doi.org/10.1093/carcin/bgv006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400529PMC
March 2015

A modified approach to induce predictable congestive heart failure by volume overload in rats.

PLoS One 2014 31;9(1):e87531. Epub 2014 Jan 31.

Department of Anesthesiology and Intensive Care Medicine, Campus Charité, Mitte and Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087531PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909118PMC
October 2014

New insights into mechanisms of opioid inhibitory effects on capsaicin-induced TRPV1 activity during painful diabetic neuropathy.

Neuropharmacology 2014 Oct 24;85:142-50. Epub 2014 May 24.

Department of Anaesthesiology and Intensive Care Medicine, Charité University Berlin, Campus Virchow Klinikum and Campus Charite Mitte, Augustenburgerplatz 1, 13353 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2014.05.026DOI Listing
October 2014

Curcumin chemosensitizes 5-fluorouracil resistant MMR-deficient human colon cancer cells in high density cultures.

PLoS One 2014 3;9(1):e85397. Epub 2014 Jan 3.

Gastrointestinal Cancer Research Laboratory, Division of Gastroenterology, Baylor Research Institute and Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085397PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880338PMC
September 2014

Sirtuin-1 (SIRT1) is required for promoting chondrogenic differentiation of mesenchymal stem cells.

J Biol Chem 2014 Aug 24;289(32):22048-62. Epub 2014 Jun 24.

From the Institute of Anatomy, Musculoskeletal Research Group, Ludwig-Maximilian-University Munich, Pettenkoferstrasse 11, D-80336 Munich, Germany,

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http://dx.doi.org/10.1074/jbc.M114.568790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139220PMC
August 2014

Reduced number, G protein coupling, and antinociceptive efficacy of spinal mu-opioid receptors in diabetic rats are reversed by nerve growth factor.

J Pain 2013 Jul 24;14(7):720-30. Epub 2013 Apr 24.

Department of Anaesthesiology and Intensive Care Medicine, Charité University Berlin, Campus Virchow Klinikum and Campus Charite Mitte, Berlin, Germany.

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http://dx.doi.org/10.1016/j.jpain.2013.01.776DOI Listing
July 2013

Large scale expansion of human umbilical cord cells in a rotating bed system bioreactor for cardiovascular tissue engineering applications.

Open Biomed Eng J 2013 14;7:50-61. Epub 2013 Jun 14.

Department of Cardiothoracic and Vascular Surgery and Laboratory for Tissue Engineering, German Heart Institute Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.

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http://dx.doi.org/10.2174/1874120701307010050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706833PMC
July 2013

Osteogenic effects of resveratrol in vitro: potential for the prevention and treatment of osteoporosis.

Ann N Y Acad Sci 2013 Jul;1290:59-66

Medical Research Council-Arthritis Research UK Centre for Musculoskeletal Ageing Research, Arthritis Research UK Pain Centre, Arthritis Research UK Centre for Sport, Exercise, and Osteoarthritis, Faculty of Medicine and Health Sciences, The University of Nottingham, United Kingdom.

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http://dx.doi.org/10.1111/nyas.12145DOI Listing
July 2013

Rab7 silencing prevents μ-opioid receptor lysosomal targeting and rescues opioid responsiveness to strengthen diabetic neuropathic pain therapy.

Diabetes 2013 Apr 10;62(4):1308-19. Epub 2012 Dec 10.

Department of Anaesthesiology and Intensive Care Medicine, Charité University Berlin, Campus Virchow Klinikum and Campus Charite Mitte, Berlin, Germany.

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http://dx.doi.org/10.2337/db12-0590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609597PMC
April 2013

Effects of mycophenolic acid alone and in combination with its metabolite mycophenolic acid glucuronide on rat embryos in vitro.

Arch Toxicol 2013 Feb 23;87(2):361-70. Epub 2012 Aug 23.

Institute for Clinical Pharmacology and Toxicology, Charité, Universitätsmedizin, Luisenstraße 7, 10117 Berlin, Germany.

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http://dx.doi.org/10.1007/s00204-012-0922-3DOI Listing
February 2013

Resveratrol modulates interleukin-1β-induced phosphatidylinositol 3-kinase and nuclear factor κB signaling pathways in human tenocytes.

J Biol Chem 2012 Nov 30;287(45):38050-63. Epub 2012 Aug 30.

Institute of Anatomy, Ludwig-Maximilian-University Munich, 80336 Munich, Germany.

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http://dx.doi.org/10.1074/jbc.M112.377028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488075PMC
November 2012

Botanical Extracts from Rosehip (Rosa canina), Willow Bark (Salix alba), and Nettle Leaf (Urtica dioica) Suppress IL-1β-Induced NF-κB Activation in Canine Articular Chondrocytes.

Evid Based Complement Alternat Med 2012 14;2012:509383. Epub 2012 Mar 14.

Musculoskeletal Research Group, Institute of Anatomy, Ludwig-Maximilian-University Munich, 80336 Munich, Germany.

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http://www.hindawi.com/journals/ecam/2012/509383/
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http://dx.doi.org/10.1155/2012/509383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312281PMC
August 2012

Midkine acts as proangiogenic cytokine in hypoxia-induced angiogenesis.

Am J Physiol Heart Circ Physiol 2012 Aug 15;303(4):H429-38. Epub 2012 Jun 15.

Walter Brendel Centre of Experimental Medicine, Ludwig Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1152/ajpheart.00934.2011DOI Listing
August 2012

Sirt-1 is required for the inhibition of apoptosis and inflammatory responses in human tenocytes.

J Biol Chem 2012 Jul 11;287(31):25770-81. Epub 2012 Jun 11.

Institute of Anatomy, Ludwig-Maximilians-University Munich, Munich 80336 Germany.

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http://dx.doi.org/10.1074/jbc.M112.355420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406664PMC
July 2012

Three-dimensional high-density co-culture with primary tenocytes induces tenogenic differentiation in mesenchymal stem cells.

J Orthop Res 2011 Sep 15;29(9):1351-60. Epub 2011 Mar 15.

Musculoskeletal Research Group, Institute of Anatomy, Ludwig Maximilian University of Munich, Pettenkoferstrasse 11, 80336 Munich, Germany.

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http://doi.wiley.com/10.1002/jor.21400
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http://dx.doi.org/10.1002/jor.21400DOI Listing
September 2011

Curcumin synergizes with resveratrol to stimulate the MAPK signaling pathway in human articular chondrocytes in vitro.

Genes Nutr 2011 May 25;6(2):171-9. Epub 2010 May 25.

Musculoskeletal Research Group, Institute of Anatomy, Ludwig-Maximilians-University Munich, Pettenkoferstrasse 11, 80336, Munich, Germany,

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http://dx.doi.org/10.1007/s12263-010-0179-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092909PMC
May 2011

TNF-alpha-induced mitochondrial alterations in human T cells requires FADD and caspase-8 activation but not RIP and caspase-3 activation.

Antioxid Redox Signal 2010 Sep;13(6):821-31

Musculoskeletal Research Group, Institute of Anatomy, Ludwig-Maximilian-University Munich, Munich, Germany.

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http://dx.doi.org/10.1089/ars.2009.3036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935348PMC
September 2010

Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1beta-induced NF-kappaB-mediated inflammation and apoptosis.

Arthritis Res Ther 2009 4;11(6):R165. Epub 2009 Nov 4.

Musculoskeletal Research Group, Institute of Anatomy, Ludwig-Maximilians-University Munich, Pettenkoferstrasse 11, 80336 Munich, Germany.

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http://dx.doi.org/10.1186/ar2850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003513PMC
May 2010

Synergistic effects of dexamethasone and quinolones on human-derived tendon cells.

Int J Antimicrob Agents 2010 Apr 19;35(4):366-74. Epub 2010 Jan 19.

Institute of Clinical Pharmacology and Toxicology, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Garystr. 5, 14195 Berlin, Germany.

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http://dx.doi.org/10.1016/j.ijantimicag.2009.10.009DOI Listing
April 2010

Expression of aquaporin 1 (AQP1) in human synovitis.

Ann Anat 2010 Apr 25;192(2):116-21. Epub 2010 Jan 25.

Division of Veterinary Medicine, School of Veterinary Medicine and Science, Faculty of Medicine and Health Sciences, University of Nottingham, Sutton Bonington Campus, Sutton Bonington LE12 5RD, UK.

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http://dx.doi.org/10.1016/j.aanat.2010.01.001DOI Listing
April 2010

The transmembrane domains of L-selectin and CD44 regulate receptor cell surface positioning and leukocyte adhesion under flow.

J Biol Chem 2010 Apr 8;285(18):13490-7. Epub 2010 Mar 8.

Central Department of Laboratory Medicine and Pathobiochemistry, Charité-Universitätsmedizin, 10117 Berlin, Germany.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M110.102640
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http://dx.doi.org/10.1074/jbc.M110.102640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859509PMC
April 2010

Effects of moxifloxacin and clinafloxacin on murine limb buds cultured in regular and in magnesium-deficient medium.

Arch Toxicol 2010 Mar 1;84(3):221-6. Epub 2009 Dec 1.

Federal Office of Consumer Protection and Food Safety, Mauerstr. 39-42, 10117 Berlin, Germany.

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http://link.springer.com/10.1007/s00204-009-0490-3
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http://dx.doi.org/10.1007/s00204-009-0490-3DOI Listing
March 2010

Mesenchymal stem cells in regenerative medicine: opportunities and challenges for articular cartilage and intervertebral disc tissue engineering.

J Cell Physiol 2010 Jan;222(1):23-32

Tissue Injury and Repair Group, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1002/jcp.21915DOI Listing
January 2010

Anabolic actions of IGF-I and TGF-beta1 on Interleukin-1beta-treated human articular chondrocytes: evaluation in two and three dimensional cultures.

Histol Histopathol 2009 10;24(10):1245-62

Musculoskeletal Research Group, Institute of Anatomy, Ludwig-Maximilian-University Munich, Munich, Germany.

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http://dx.doi.org/10.14670/HH-24.1245DOI Listing
October 2009

Interleukin-1beta-induced extracellular matrix degradation and glycosaminoglycan release is inhibited by curcumin in an explant model of cartilage inflammation.

Ann N Y Acad Sci 2009 Aug;1171:428-35

Division of Veterinary Medicine, School of Veterinary Medicine and Science, University of Nottingham, Leicestershire, United Kingdom.

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http://dx.doi.org/10.1111/j.1749-6632.2009.04687.xDOI Listing
August 2009

Resveratrol addiction: to die or not to die.

Mol Nutr Food Res 2009 Jan;53(1):115-28

Institute of Anatomy, Ludwig-Maximilian-University Munich, Munich, Germany.

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http://dx.doi.org/10.1002/mnfr.200800148DOI Listing
January 2009

Resveratrol suppresses interleukin-1beta-induced inflammatory signaling and apoptosis in human articular chondrocytes: potential for use as a novel nutraceutical for the treatment of osteoarthritis.

Biochem Pharmacol 2008 Dec 3;76(11):1426-39. Epub 2008 Jun 3.

Ludwig-Maximilians-University Munich, Faculty of Medicine, Institute of Anatomy, Musculoskeletal Research Group, Pettenkoferstrasse 11, D-80336 Munich, Germany.

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http://dx.doi.org/10.1016/j.bcp.2008.05.029DOI Listing
December 2008

Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain.

J Clin Invest 2008 Mar;118(3):1065-73

Klinik für Anaesthesiologie und operative Intensivmedizin, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.

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http://dx.doi.org/10.1172/JCI25911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2214843PMC
March 2008

Human apolipoprotein A-I gene transfer reduces the development of experimental diabetic cardiomyopathy.

Circulation 2008 Mar 10;117(12):1563-73. Epub 2008 Mar 10.

Abteilung für Kardiologie und Pneumologie, Charité-Universitätsklinikum Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.107.710830DOI Listing
March 2008

In utero and lactational exposures to low doses of polybrominated diphenyl ether-47 alter the reproductive system and thyroid gland of female rat offspring.

Environ Health Perspect 2008 Mar;116(3):308-14

Department of Toxicology, Institute of Clinical Pharmacology and Toxicology, Campus Benjamin Franklin, Charité University Medical School Berlin, Berlin, Germany.

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http://dx.doi.org/10.1289/ehp.10536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265047PMC
March 2008

Regulation of inflammation signalling by resveratrol in human chondrocytes in vitro.

Biochem Pharmacol 2008 Feb 18;75(3):677-87. Epub 2007 Sep 18.

Ludwig-Maximilians-University Munich, Faculty of Medicine, Institute of Anatomy, Pettenkoferstrasse 11, Munich, Germany.

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http://dx.doi.org/10.1016/j.bcp.2007.09.014DOI Listing
February 2008

Accelerated mitochondrial adenosine diphosphate/adenosine triphosphate transport improves hypertension-induced heart disease.

Circulation 2007 Jan 8;115(3):333-44. Epub 2007 Jan 8.

Charité-Universitätsmedizin, Campus Benjamin Franklin, Department of Cardiology and Pneumonology, Hindenburgdamm 30, 12200 Berlin, Germany.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.106.643296DOI Listing
January 2007

Resveratrol inhibits IL-1 beta-induced stimulation of caspase-3 and cleavage of PARP in human articular chondrocytes in vitro.

Ann N Y Acad Sci 2007 Jan;1095:554-63

Institute of Anatomy, Musculoskeletal Research Group, Ludwig-Maximilian-University Munich, Pettenkoferstrasse 11, D-80336 Munich.

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http://dx.doi.org/10.1196/annals.1397.060DOI Listing
January 2007

Regulation of 2-deoxy-D-glucose transport, lactate metabolism, and MMP-2 secretion by the hypoxia mimetic cobalt chloride in articular chondrocytes.

Ann N Y Acad Sci 2006 Dec;1091:83-93

Molecular Pathogenesis and Connective Tissue Research, Department of Veterinary Preclinical Sciences, Faculty of Veterinary Science, University of Liverpool, Brownlow Hill and Crown Street, Liverpool, UK.

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http://dx.doi.org/10.1196/annals.1378.057DOI Listing
December 2006

Igf-I extends the chondrogenic potential of human articular chondrocytes in vitro: molecular association between Sox9 and Erk1/2.

Biochem Pharmacol 2006 Nov 29;72(11):1382-95. Epub 2006 Sep 29.

Institute of Anatomy, Ludwig-Maximilians-University, Pettenkoferstrasse 11, 80336 Munich, Germany.

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http://dx.doi.org/10.1016/j.bcp.2006.08.022DOI Listing
November 2006

Effects of 2,3,7,8-tetrachloro-dibenzo-p-dioxin on the extracellular matrix of the thymus in juvenile marmosets (Callithrix jacchus).

Toxicology 2006 Sep 14;226(2-3):197-207. Epub 2006 Jul 14.

Institute of Clinical Pharmacology and Toxicology, Charité Campus Benjamin Franklin, Garystrasse 5, 14195 Berlin, Germany.

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http://dx.doi.org/10.1016/j.tox.2006.07.010DOI Listing
September 2006

Short-term culture of human neonatal myofibroblasts seeded using a novel three-dimensional rotary seeding device.

ASAIO J 2006 May-Jun;52(3):310-4

Department of Thoracic and Cardiovascular Surgery, Laboratory for Tissue Engineering, Berlin, Germany.

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https://insights.ovid.com/crossref?an=00002480-200605000-000
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http://dx.doi.org/10.1097/01.mat.0000217792.45523.bbDOI Listing
August 2006

A hypothesis for the origin and pathogenesis of rheumatoid diseases.

Rheumatol Int 2006 May 14;26(7):641-54. Epub 2005 Dec 14.

Institute of Indoor Diagnostics, Marconistrasse 23, 40589 Duesseldorf, Germany.

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http://dx.doi.org/10.1007/s00296-005-0088-xDOI Listing
May 2006

Simulated weightlessness changes the cytoskeleton and extracellular matrix proteins in papillary thyroid carcinoma cells.

Cell Tissue Res 2006 May 24;324(2):267-77. Epub 2006 Jan 24.

Department of Trauma and Reconstructive Surgery, Charité University Medical School, Center of Space Medicine, Benjamin Franklin Medical Center, 12200, Berlin, Germany.

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http://dx.doi.org/10.1007/s00441-005-0142-8DOI Listing
May 2006

Curcumin protects human chondrocytes from IL-l1beta-induced inhibition of collagen type II and beta1-integrin expression and activation of caspase-3: an immunomorphological study.

Ann Anat 2005 Nov;187(5-6):487-97

Musculoskeletal Research Group, Institute of Anatomy, Ludwig-Maximilians-University Munich, Pettenkoferstrasse 11, 80336 Munich, Germany.

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http://dx.doi.org/10.1016/j.aanat.2005.06.007DOI Listing
November 2005

Nutraceutical therapies for degenerative joint diseases: a critical review.

Crit Rev Food Sci Nutr 2005 ;45(3):145-64

Connective Tissue Research Group, Faculty of Veterinary Science, University of Liverpool, Liverpool, United Kingdom.

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http://dx.doi.org/10.1080/10408690590956341DOI Listing
October 2005

Increase of fibronectin and osteopontin in porcine hearts following ischemia and reperfusion.

J Mol Med (Berl) 2005 Aug 16;83(8):626-37. Epub 2005 Mar 16.

Institute of Clinical Pharmacology and Toxicology, Benjamin Franklin Medical Center, Charité-University Medical School, Garystr. 5, 14195 Berlin, Germany.

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http://link.springer.com/10.1007/s00109-005-0642-8
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August 2005

Fluoroquinolones cause changes in extracellular matrix, signalling proteins, metalloproteinases and caspase-3 in cultured human tendon cells.

Toxicology 2005 Aug;212(1):24-36

Institute of Clinical Pharmacology and Toxicology, Department of Toxicology, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Garystr. 5, 14195 Berlin, Germany.

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http://dx.doi.org/10.1016/j.tox.2005.04.002DOI Listing
August 2005

Ultrastructural changes observed in rat ovaries following in utero and lactational exposure to low doses of a polybrominated flame retardant.

Toxicol Lett 2005 Jul 29;157(3):189-202. Epub 2005 Mar 29.

Charité University Medical School Berlin, Campus Benjamin Franklin, Institute of Clinical Pharmacology and Toxicology, Department of Toxicology, Garystr. 5, 14195 Berlin, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S03784274050005
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http://dx.doi.org/10.1016/j.toxlet.2005.02.001DOI Listing
July 2005

Redox regulation of apoptosis by members of the TNF superfamily.

Antioxid Redox Signal 2005 Mar-Apr;7(3-4):482-96

Institute of Anatomy, Ludwig-Maximilians-University Munich, Munich, Germany.

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http://dx.doi.org/10.1089/ars.2005.7.482DOI Listing
June 2005

Intraluminal application of vascular endothelial growth factor enhances healing of microvascular anastomosis in a rat model.

J Vasc Res 2005 May-Jun;42(3):202-13. Epub 2005 Apr 14.

Department of Trauma and Reconstructive Surgery, Charité-University Medicine Berlin, Benjamin Franklin Campus, Hindenburgdamm 30, DE-12200 Berlin, Germany.

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http://dx.doi.org/10.1159/000085176DOI Listing
June 2005

Effects of curcumin (diferuloylmethane) on nuclear factor kappaB signaling in interleukin-1beta-stimulated chondrocytes.

Ann N Y Acad Sci 2004 Dec;1030:578-86

Charité University Medical School Berlin, Institute of Anatomy, Department of Cell and Neurobiology, Campus Benjamin Franklin, Königin-Luise-Strasse 15, D-14195 Berlin, Germany.

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http://dx.doi.org/10.1196/annals.1329.067DOI Listing
December 2004

Longterm conditions of mimicked weightlessness influences the cytoskeleton in thyroid cells.

J Gravit Physiol 2004 Jul;11(2):P169-72

Department of Trauma and Reconstructive Surgery, Charité University Medicine, Berlin, Germany.

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July 2004

Vascular endothelial growth factor inhibits programmed cell death of endothelial cells induced by clinorotation.

J Gravit Physiol 2004 Jul;11(2):P199-200

Department of Trauma and Reconstructive Surgery, Charité Unviersity Medicine Berlin, Germany.

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July 2004

Loss of chondrogenic potential in dedifferentiated chondrocytes correlates with deficient Shc-Erk interaction and apoptosis.

Osteoarthritis Cartilage 2004 Jun;12(6):448-58

Charité University Medical School, Campus Benjamin Franklin, Institute of Anatomy, Department of Cell and Neurobiology, Berlin, Germany.

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http://dx.doi.org/10.1016/j.joca.2004.02.007DOI Listing
June 2004

[Effect of a Harpagophytum procumbens DC extract on matrix metalloproteinases in human chondrocytes in vitro].

Arzneimittelforschung 2004 ;54(4):213-20

Institut für Anatomie, Universitätsklinikum Benjamin Franklin, Charité Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1055/s-0031-1296962DOI Listing
June 2004

Simulated microgravity induces programmed cell death in human thyroid carcinoma cells.

J Gravit Physiol 2002 Jul;9(1):P295-6

Institute of Clinical Pharmacology and Toxicology, Benjamin Franklin Medical Center, Freie Universitat Berlin, Germany.

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July 2002