Megan L Wolfe

Megan L Wolfe

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Megan L Wolfe

Megan L Wolfe

Publications by authors named "Megan L Wolfe"

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Mining the LIPG allelic spectrum reveals the contribution of rare and common regulatory variants to HDL cholesterol.

PLoS Genet 2011 Dec 8;7(12):e1002393. Epub 2011 Dec 8.

Institute for Translational Medicine and Therapeutics, Institute for Diabetes, Obesity, and Metabolism, and Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1002393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234219PMC
December 2011

Lipoprotein(a) is strongly associated with coronary artery calcification in type-2 diabetic women.

Int J Cardiol 2011 Jul 19;150(1):17-21. Epub 2010 Mar 19.

Department of Medicine, Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, United States.

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http://dx.doi.org/10.1016/j.ijcard.2010.02.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132301PMC
July 2011

Effect of rosiglitazone on HDL metabolism in subjects with metabolic syndrome and low HDL.

J Lipid Res 2011 Jan 22;52(1):136-42. Epub 2010 Oct 22.

Department of Pharmacology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://www.jlr.org/lookup/doi/10.1194/jlr.P008136
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http://dx.doi.org/10.1194/jlr.P008136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999935PMC
January 2011

Inflammation induces fibrinogen nitration in experimental human endotoxemia.

Free Radic Biol Med 2009 Oct 22;47(8):1140-6. Epub 2009 Jul 22.

Cardiovascular Institute, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2009.07.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651370PMC
October 2009

A naturally occurring variant of endothelial lipase associated with elevated HDL exhibits impaired synthesis.

J Lipid Res 2009 Sep 3;50(9):1910-6. Epub 2009 May 3.

Department of Medicine and Institute for Translational Medicine and Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104.

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http://dx.doi.org/10.1194/jlr.P900020-JLR200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724790PMC
September 2009

Evaluating the association between all components of the metabolic syndrome and pre-eclampsia.

J Matern Fetal Neonatal Med 2009 Jun;22(6):501-9

Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1080/14767050902794642DOI Listing
June 2009

Resistin gene variation is associated with systemic inflammation but not plasma adipokine levels, metabolic syndrome or coronary atherosclerosis in nondiabetic Caucasians.

Clin Endocrinol (Oxf) 2009 May 15;70(5):698-705. Epub 2008 Aug 15.

Cardiovascular Institute, Institute for Translational Medicine and Therapeutics, and Department of Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6160, USA.

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http://dx.doi.org/10.1111/j.1365-2265.2008.03375.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108432PMC
May 2009

Atheroprotective lipoprotein effects of a niacin-simvastatin combination compared to low- and high-dose simvastatin monotherapy.

Am Heart J 2009 Apr 23;157(4):687.e1-8. Epub 2009 Feb 23.

The Cardiovascular Institute and the Institute for Translational Medicine and Therapeutics, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.ahj.2009.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088112PMC
April 2009

Adipokines, insulin resistance, and coronary artery calcification.

J Am Coll Cardiol 2008 Jul;52(3):231-6

Cardiovascular Institute and Institute for Translational Medicine and Therapeutics, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S073510970801477
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http://dx.doi.org/10.1016/j.jacc.2008.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853595PMC
July 2008

The influence of pravastatin and atorvastatin on markers of oxidative stress in hypercholesterolemic humans.

J Am Coll Cardiol 2008 Apr;51(17):1653-62

Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6160, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S073510970800496
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http://dx.doi.org/10.1016/j.jacc.2008.01.026DOI Listing
April 2008

Endothelial lipase is increased in vivo by inflammation in humans.

Circulation 2008 Feb 22;117(5):678-85. Epub 2008 Jan 22.

School of Nursing, and Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.107.707349DOI Listing
February 2008

Innate immunity modulates adipokines in humans.

J Clin Endocrinol Metab 2007 Jun 20;92(6):2272-9. Epub 2007 Mar 20.

Cardiovascular Institute, University of Pennsylvania Medical Center, Philadelphia, PA 19104-6160, USA.

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http://dx.doi.org/10.1210/jc.2006-2545DOI Listing
June 2007

Value of electrocardiographic and ankle-brachial index abnormalities for prediction of coronary atherosclerosis in asymptomatic subjects with type 2 diabetes mellitus.

Am J Cardiol 2007 Apr 14;99(7):951-5. Epub 2007 Feb 14.

Cardiovascular Institute, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, and Department of Medicine, Philadelphia Veterans Affairs Medical Center, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.amjcard.2006.11.040DOI Listing
April 2007

Plasma cytokines, metabolic syndrome, and atherosclerosis in humans.

J Investig Med 2007 Jan;55(1):26-35

Cardiovascular Institute, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6160, USA.

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January 2007

Effects of rosiglitazone on lipids, adipokines, and inflammatory markers in nondiabetic patients with low high-density lipoprotein cholesterol and metabolic syndrome.

Arterioscler Thromb Vasc Biol 2006 Mar 15;26(3):624-30. Epub 2005 Dec 15.

Cardiovascular Division, Department of Medicine, Cardiovascular Institute, University of Pennsylvania Medical Center, Philadelphia, PA, USA.

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http://dx.doi.org/10.1161/01.ATV.0000200136.56716.30DOI Listing
March 2006

Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosis.

PLoS Med 2006 Feb 20;3(2):e22. Epub 2005 Dec 20.

Institute for Translational Medicine and Therapeutics, School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1371/journal.pmed.0030022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1316064PMC
February 2006

Effects of pioglitazone on lipoproteins, inflammatory markers, and adipokines in nondiabetic patients with metabolic syndrome.

Arterioscler Thromb Vasc Biol 2006 Jan 10;26(1):182-8. Epub 2005 Nov 10.

Division of General Internal Medicine, Institute for Translational Medicine and Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1161/01.ATV.0000195790.24531.4fDOI Listing
January 2006

Higher order lipase gene association with plasma triglycerides.

J Lipid Res 2005 Sep 16;46(9):1914-22. Epub 2005 Jun 16.

Cardiovascular Division and Institute for Translational Medicine and Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1194/jlr.M500042-JLR200DOI Listing
September 2005

Resistin is an inflammatory marker of atherosclerosis in humans.

Circulation 2005 Feb 14;111(7):932-9. Epub 2005 Feb 14.

Division of Cardiology, Center for Experimental Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, Pa, USA.

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http://dx.doi.org/10.1161/01.CIR.0000155620.10387.43DOI Listing
February 2005

Intercellular adhesion molecule 1 (ICAM-1) gene variant is associated with coronary artery calcification independent of soluble ICAM-1 levels.

J Investig Med 2004 Dec;52(8):515-22

Cardiovascular Division, Department of Medicine, the Center for Experimental Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1136/jim-52-08-23DOI Listing
December 2004

Measures of insulin resistance add incremental value to the clinical diagnosis of metabolic syndrome in association with coronary atherosclerosis.

Circulation 2004 Aug 2;110(7):803-9. Epub 2004 Aug 2.

Cardiovascular Division and Center for Experimental Therapeutics, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pa, USA.

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http://dx.doi.org/10.1161/01.CIR.0000138740.84883.9CDOI Listing
August 2004

Plasma leptin levels are associated with coronary atherosclerosis in type 2 diabetes.

J Clin Endocrinol Metab 2004 Aug;89(8):3872-8

Cardiovascular Division, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, USA.

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http://dx.doi.org/10.1210/jc.2003-031676DOI Listing
August 2004

Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol.

N Engl J Med 2004 Apr;350(15):1505-15

Lipid Research Laboratory, Division of Endocrinology, Metabolism, Diabetes, and Molecular Medicine, New England Medical Center and Tufts University School of Medicine, Boston, MA 02111, USA.

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http://dx.doi.org/10.1056/NEJMoa031766DOI Listing
April 2004

Coronary artery calcification and cardiovascular risk factors: impact of the analytic approach.

Atherosclerosis 2004 Mar;173(1):69-78

Cardiovascular Division, Department of Medicine, Center for Experimental Therapeutics, University of Pennsylvania School of Medicine, 909 BRB 2/3, 421 Curie Blvd., Philadelphia, PA 19004-6160, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2003.10.010DOI Listing
March 2004

C-reactive protein and coronary artery calcification: The Study of Inherited Risk of Coronary Atherosclerosis (SIRCA).

Arterioscler Thromb Vasc Biol 2003 Oct 21;23(10):1851-6. Epub 2003 Aug 21.

Cardiovascular Division, University of Pennsylvania School of Medicine, Philadelphia, USA.

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http://dx.doi.org/10.1161/01.ATV.0000092327.60858.4ADOI Listing
October 2003

Guggulipid for the treatment of hypercholesterolemia: a randomized controlled trial.

JAMA 2003 Aug;290(6):765-72

Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104-6021, USA.

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http://dx.doi.org/10.1001/jama.290.6.765DOI Listing
August 2003

Coronary artery calcification at electron beam computed tomography is increased in asymptomatic type 2 diabetics independent of traditional risk factors.

J Cardiovasc Risk 2002 Dec;9(6):369-76

Department of Medicine, University of Pennsylvania, 421 Curie Boulevard, 815 BRB2/3, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1097/01.hjr.0000049242.21319.a7DOI Listing
December 2002

The frequency of the cholesteryl ester transfer protein-TaqI B2 allele is lower in African Americans than in Caucasians.

Atherosclerosis 2002 Jul;163(1):169-74

Department of Medicine, University of Pennsylvania, School of Medicine, 654 BRB II/III, 421 Curie Blvd, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/s0021-9150(01)00769-9DOI Listing
July 2002