Meenhard Herlyn

Meenhard Herlyn

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Meenhard Herlyn

Publications by authors named "Meenhard Herlyn"

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A Melanoma Patient-Derived Xenograft Model.

J Vis Exp 2019 May 20(147). Epub 2019 May 20.

Wistar Institute.

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http://dx.doi.org/10.3791/59508DOI Listing
May 2019

Publisher Correction: Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma.

Nat Med 2018 Dec;24(12):1942

Center for Bioinformatics and Computational Biology, Department of Computer Science, University of Maryland, College Park, MD, USA.

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http://dx.doi.org/10.1038/s41591-018-0247-8DOI Listing
December 2018

Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma.

Nat Med 2018 10 20;24(10):1545-1549. Epub 2018 Aug 20.

Center for Bioinformatics and Computational Biology, Department of Computer Science, University of Maryland, College Park, MD, USA.

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http://www.nature.com/articles/s41591-018-0157-9
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http://dx.doi.org/10.1038/s41591-018-0157-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693632PMC
October 2018

Targeting the Warburg effect via LDHA inhibition engages ATF4 signaling for cancer cell survival.

EMBO J 2018 Oct 12;37(20). Epub 2018 Sep 12.

Tumor Initiation and Maintenance Program, Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA

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http://dx.doi.org/10.15252/embj.201899735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187221PMC
October 2018

Endogenous authentic OCT4A proteins directly regulate FOS/AP-1 transcription in somatic cancer cells.

Cell Death Dis 2018 May 22;9(6):585. Epub 2018 May 22.

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310003, China.

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http://dx.doi.org/10.1038/s41419-018-0606-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964179PMC
May 2018

Acetylsalicylic Acid Governs the Effect of Sorafenib in -Mutant Cancers.

Clin Cancer Res 2018 03 1;24(5):1090-1102. Epub 2017 Dec 1.

Dermatology Research Centre, The University of Queensland, The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-2118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844814PMC
March 2018

Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids.

Cancer Discov 2018 02 3;8(2):196-215. Epub 2017 Nov 3.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-17-0833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809290PMC
February 2018

Hypoxia-activated prodrug enhances therapeutic effect of sunitinib in melanoma.

Oncotarget 2017 Dec 5;8(70):115140-115152. Epub 2017 Dec 5.

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.18632/oncotarget.22944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777760PMC
December 2017

JARID1 Histone Demethylases: Emerging Targets in Cancer.

Trends Cancer 2017 10 12;3(10):713-725. Epub 2017 Sep 12.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA; The Wistar Institute, Philadelphia, PA 19104, USA; Philadelphia VA Medical Center, Philadelphia, PA 19104, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S24058033173016
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http://dx.doi.org/10.1016/j.trecan.2017.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679451PMC
October 2017

FANTOM5 CAGE profiles of human and mouse samples.

Authors:
Shuhei Noguchi Takahiro Arakawa Shiro Fukuda Masaaki Furuno Akira Hasegawa Fumi Hori Sachi Ishikawa-Kato Kaoru Kaida Ai Kaiho Mutsumi Kanamori-Katayama Tsugumi Kawashima Miki Kojima Atsutaka Kubosaki Ri-Ichiroh Manabe Mitsuyoshi Murata Sayaka Nagao-Sato Kenichi Nakazato Noriko Ninomiya Hiromi Nishiyori-Sueki Shohei Noma Eri Saijyo Akiko Saka Mizuho Sakai Christophe Simon Naoko Suzuki Michihira Tagami Shoko Watanabe Shigehiro Yoshida Peter Arner Richard A Axton Magda Babina J Kenneth Baillie Timothy C Barnett Anthony G Beckhouse Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher Ailsa J Carlisle Hans C Clevers Carrie A Davis Michael Detmar Taeko Dohi Albert S B Edge Matthias Edinger Anna Ehrlund Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Afsaneh Eslami Michela Fagiolini Lynsey Fairbairn Mary C Farach-Carson Geoffrey J Faulkner Carmelo Ferrai Malcolm E Fisher Lesley M Forrester Rie Fujita Jun-Ichi Furusawa Teunis B Geijtenbeek Thomas Gingeras Daniel Goldowitz Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Yuki Hasegawa Meenhard Herlyn Peter Heutink Kelly J Hitchens David A Hume Tomokatsu Ikawa Yuri Ishizu Chieko Kai Hiroshi Kawamoto Yuki I Kawamura Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura Sarah Klein S Peter Klinken Alan J Knox Soichi Kojima Haruhiko Koseki Shigeo Koyasu Weonju Lee Andreas Lennartsson Alan Mackay-Sim Niklas Mejhert Yosuke Mizuno Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Kelly J Morris Hozumi Motohashi Christine L Mummery Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Tadasuke Nozaki Soichi Ogishima Naganari Ohkura Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Robert Passier Margaret Patrikakis Ana Pombo Swati Pradhan-Bhatt Xian-Yang Qin Michael Rehli Patrizia Rizzu Sugata Roy Antti Sajantila Shimon Sakaguchi Hiroki Sato Hironori Satoh Suzana Savvi Alka Saxena Christian Schmidl Claudio Schneider Gundula G Schulze-Tanzil Anita Schwegmann Guojun Sheng Jay W Shin Daisuke Sugiyama Takaaki Sugiyama Kim M Summers Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Andru Tomoiu Hiroo Toyoda Marc van de Wetering Linda M van den Berg Roberto Verardo Dipti Vijayan Christine A Wells Louise N Winteringham Ernst Wolvetang Yoko Yamaguchi Masayuki Yamamoto Chiyo Yanagi-Mizuochi Misako Yoneda Yohei Yonekura Peter G Zhang Silvia Zucchelli Imad Abugessaisa Erik Arner Jayson Harshbarger Atsushi Kondo Timo Lassmann Marina Lizio Serkan Sahin Thierry Sengstag Jessica Severin Hisashi Shimoji Masanori Suzuki Harukazu Suzuki Jun Kawai Naoto Kondo Masayoshi Itoh Carsten O Daub Takeya Kasukawa Hideya Kawaji Piero Carninci Alistair R R Forrest Yoshihide Hayashizaki

Sci Data 2017 08 29;4:170112. Epub 2017 Aug 29.

RIKEN Omics Science Center, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1038/sdata.2017.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574368PMC
August 2017

Oncogenic RAS Regulates Long Noncoding RNA in Human Cancer.

Cancer Res 2017 07 4;77(14):3745-3757. Epub 2017 May 4.

Center for Research on Reproduction & Women's Health, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511552PMC
July 2017

Inhibition of stress-inducible HSP70 impairs mitochondrial proteostasis and function.

Oncotarget 2017 Jul;8(28):45656-45669

Department of Genetics, The Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.18632/oncotarget.17321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542216PMC
July 2017

Targeting the ATR/CHK1 Axis with PARP Inhibition Results in Tumor Regression in -Mutant Ovarian Cancer Models.

Clin Cancer Res 2017 06 19;23(12):3097-3108. Epub 2016 Dec 19.

Penn Ovarian Cancer Research Center, Division of Gynecologic Oncology, Department of Obstetrics & Gynecology, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-2273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474193PMC
June 2017

Recent Advances in Melanoma and Melanocyte Biology.

J Invest Dermatol 2017 03 12;137(3):557-560. Epub 2017 Jan 12.

Molecular and Cellular Oncogenesis Program and Melanoma Research Center, The Wistar Institute, Philadelphia, Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.11.004DOI Listing
March 2017

PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma.

PLoS Genet 2016 Dec 15;12(12):e1006518. Epub 2016 Dec 15.

Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, Charleston, South Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207760PMC
December 2016

Randy Lomax, 1947-2016.

Authors:
Meenhard Herlyn

Pigment Cell Melanoma Res 2016 11;29(6):605-606

The Wistar Institute, Philadelphia, PA.

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http://dx.doi.org/10.1111/pcmr.12539DOI Listing
November 2016

Targeting RRM2 and Mutant BRAF Is a Novel Combinatorial Strategy for Melanoma.

Mol Cancer Res 2016 09 13;14(9):767-75. Epub 2016 Jun 13.

Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1541-7786.MCR-16-0099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025362PMC
September 2016

JARID1B Enables Transit between Distinct States of the Stem-like Cell Population in Oral Cancers.

Cancer Res 2016 09 3;76(18):5538-49. Epub 2016 Aug 3.

Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania. The Wistar Institute, Philadelphia, Pennsylvania. VA Medical Center, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-3377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026599PMC
September 2016

An Integrated Model of RAF Inhibitor Action Predicts Inhibitor Activity against Oncogenic BRAF Signaling.

Cancer Cell 2016 09 11;30(3):485-498. Epub 2016 Aug 11.

Department of Oncological Sciences, Department of Dermatology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.06.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021590PMC
September 2016

Crosstalk in skin: melanocytes, keratinocytes, stem cells, and melanoma.

J Cell Commun Signal 2016 Sep 23;10(3):191-196. Epub 2016 Aug 23.

The Wistar Institute, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/s12079-016-0349-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055506PMC
September 2016

40 years in melanoma research: an interview with Meenhard Herlyn about his career in research and the outlook for the field.

Authors:
Meenhard Herlyn

Melanoma Manag 2016 Sep 16;3(3):165-169. Epub 2016 Aug 16.

Wistar Institute, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.2217/mmt-2016-0015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094596PMC
September 2016

Mitochondrial biogenesis meets chemoresistance in BRAF-mutant melanoma.

Mol Cell Oncol 2016 Jul 2;3(4):e1179381. Epub 2016 May 2.

Molecular and Cellular Oncogenesis Program and Melanoma Research Center, The Wistar Institute , Philadelphia, PA, USA.

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http://dx.doi.org/10.1080/23723556.2016.1179381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972122PMC
July 2016

The role of Orai-STIM calcium channels in melanocytes and melanoma.

J Physiol 2016 06 6;594(11):2825-35. Epub 2016 Apr 6.

Department of Biophysics, CIPMM, School of Medicine, Saarland University, 66421, Homburg, Germany.

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http://dx.doi.org/10.1113/JP271141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887671PMC
June 2016

Nivolumab in combination with ipilimumab for the treatment of melanoma.

Expert Rev Anticancer Ther 2015 ;15(10):1135-41

a The Wistar Institute, 3601 Spruce St, Philadelphia, PA19104, USA.

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http://dx.doi.org/10.1586/14737140.2015.1093418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669949PMC
May 2016

microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB.

Oncotarget 2016 May;7(22):31663-80

Laboratory for Cancer Medicine, Harry Perkins Institute of Medical Research and University of Western Australia Centre for Medical Research, Nedlands, WA, Australia.

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http://dx.doi.org/10.18632/oncotarget.9421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077967PMC
May 2016

Notch4 Signaling Induces a Mesenchymal-Epithelial-like Transition in Melanoma Cells to Suppress Malignant Behaviors.

Cancer Res 2016 04 22;76(7):1690-7. Epub 2016 Jan 22.

Cancer Biology Unit, Department of Dermatology, Medical University Graz, Graz, Austria. Center for Medical Research (ZMF), Medical University Graz, Graz, Austria. Dermatology Research Centre, The University of Queensland, School of Medicine, Translational Research Institute, Brisbane, Queensland, Australia. Translational Research Institute, University of Queensland Diamantina Institute, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-1722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167360PMC
April 2016

The promise of 3D skin and melanoma cell bioprinting.

Melanoma Res 2016 Apr;26(2):205-6

Program of Cellular and Molecular Oncogenesis, Melanoma Research Center, The Wistar Institute, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1097/CMR.0000000000000233DOI Listing
April 2016

The role of tumor microenvironment in melanoma therapy resistance.

Melanoma Manag 2016 Mar 12;3(1):23-32. Epub 2016 Feb 12.

Division of Immunology, Allergy & Infectious Diseases (DIAID), Department of Dermatology, Medical University of Vienna, 1090 Wien, Austria.

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http://dx.doi.org/10.2217/mmt.15.37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094607PMC
March 2016

Heterogeneity in Melanoma.

Cancer Treat Res 2016 ;167:1-15

Molecular and Cellular Oncogenesis Program, Melanoma Research Center, The Wistar Institute, 3601 Spruce Street, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/978-3-319-22539-5_1DOI Listing
January 2016

The emerging roles of Oct4 in tumor-initiating cells.

Am J Physiol Cell Physiol 2015 Dec 7;309(11):C709-18. Epub 2015 Oct 7.

Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, Pennsylvania.

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http://www.physiology.org/doi/10.1152/ajpcell.00212.2015
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http://dx.doi.org/10.1152/ajpcell.00212.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725440PMC
December 2015

The macrophage: Switches from a passenger to a driver during anticancer therapy.

Oncoimmunology 2015 Dec 1;4(12):e1052929. Epub 2015 Jun 1.

The Wistar Institute ; Philadelphia, PA USA.

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http://dx.doi.org/10.1080/2162402X.2015.1052929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635944PMC
December 2015

Establishing Human Skin Grafts in Mice as Model for Melanoma Progression.

Methods Mol Biol 2015 Dec 13. Epub 2015 Dec 13.

The Wistar Institute, Melanoma Research Center, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/7651_2015_301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148711PMC
December 2015

Gα13 mediates human cytomegalovirus-encoded chemokine receptor US28-induced cell death in melanoma.

Int J Cancer 2015 Sep 16;137(6):1503-8. Epub 2015 Mar 16.

Cancer Biology Unit, Department of Dermatology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1002/ijc.29506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496263PMC
September 2015

UV-Induced Wnt7a in the Human Skin Microenvironment Specifies the Fate of Neural Crest-Like Cells via Suppression of Notch.

J Invest Dermatol 2015 Jun 23;135(6):1521-1532. Epub 2015 Feb 23.

Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2015.59DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430391PMC
June 2015

Melanoma.

Nat Rev Dis Primers 2015 04 23;1:15003. Epub 2015 Apr 23.

Department of Dermatology, University Hospital Schleswig-Holstein (UKSH), Kiel, Germany.

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http://dx.doi.org/10.1038/nrdp.2015.3DOI Listing
April 2015

KIT in melanoma: many shades of gray.

J Invest Dermatol 2015 Feb;135(2):337-338

Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X153711
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http://dx.doi.org/10.1038/jid.2014.417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669950PMC
February 2015

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.

Authors:
Erik Arner Carsten O Daub Kristoffer Vitting-Seerup Robin Andersson Berit Lilje Finn Drabløs Andreas Lennartsson Michelle Rönnerblad Olga Hrydziuszko Morana Vitezic Tom C Freeman Ahmad M N Alhendi Peter Arner Richard Axton J Kenneth Baillie Anthony Beckhouse Beatrice Bodega James Briggs Frank Brombacher Margaret Davis Michael Detmar Anna Ehrlund Mitsuhiro Endoh Afsaneh Eslami Michela Fagiolini Lynsey Fairbairn Geoffrey J Faulkner Carmelo Ferrai Malcolm E Fisher Lesley Forrester Daniel Goldowitz Reto Guler Thomas Ha Mitsuko Hara Meenhard Herlyn Tomokatsu Ikawa Chieko Kai Hiroshi Kawamoto Levon M Khachigian S Peter Klinken Soichi Kojima Haruhiko Koseki Sarah Klein Niklas Mejhert Ken Miyaguchi Yosuke Mizuno Mitsuru Morimoto Kelly J Morris Christine Mummery Yutaka Nakachi Soichi Ogishima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry Ovchinnikov Robert Passier Margaret Patrikakis Ana Pombo Xian-Yang Qin Sugata Roy Hiroki Sato Suzana Savvi Alka Saxena Anita Schwegmann Daisuke Sugiyama Rolf Swoboda Hiroshi Tanaka Andru Tomoiu Louise N Winteringham Ernst Wolvetang Chiyo Yanagi-Mizuochi Misako Yoneda Susan Zabierowski Peter Zhang Imad Abugessaisa Nicolas Bertin Alexander D Diehl Shiro Fukuda Masaaki Furuno Jayson Harshbarger Akira Hasegawa Fumi Hori Sachi Ishikawa-Kato Yuri Ishizu Masayoshi Itoh Tsugumi Kawashima Miki Kojima Naoto Kondo Marina Lizio Terrence F Meehan Christopher J Mungall Mitsuyoshi Murata Hiromi Nishiyori-Sueki Serkan Sahin Sayaka Nagao-Sato Jessica Severin Michiel J L de Hoon Jun Kawai Takeya Kasukawa Timo Lassmann Harukazu Suzuki Hideya Kawaji Kim M Summers Christine Wells David A Hume Alistair R R Forrest Albin Sandelin Piero Carninci Yoshihide Hayashizaki

Science 2015 Feb 12;347(6225):1010-4. Epub 2015 Feb 12.

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http://dx.doi.org/10.1126/science.1259418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681433PMC
February 2015

Developmental pathways activated in melanocytes and melanoma.

Arch Biochem Biophys 2014 Dec 8;563:13-21. Epub 2014 Aug 8.

Molecular and Cellular Oncogenesis Program, Melanoma Research Center, The Wistar Institute, Philadelphia, USA. Electronic address:

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http://dx.doi.org/10.1016/j.abb.2014.07.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221383PMC
December 2014

Direct conversion of mouse and human fibroblasts to functional melanocytes by defined factors.

Nat Commun 2014 Dec 16;5:5807. Epub 2014 Dec 16.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/ncomms6807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335710PMC
December 2014

Linking SOX10 to a slow-growth resistance phenotype.

Cell Res 2014 Aug 23;24(8):906-7. Epub 2014 May 23.

1] Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, PA 19104, USA [2] Melanoma Research Center, The Wistar Institute, Philadelphia, PA 19104, USA.

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http://www.nature.com/articles/cr201467
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http://dx.doi.org/10.1038/cr.2014.67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123291PMC
August 2014

Indomethacin to the rescue of TRAIL-resistant melanomas.

J Invest Dermatol 2014 May;134(5):1198-1199

Molecular and Cellular Oncogenesis Program, Melanoma Research Center, The Wistar Institute, Philadelphia, Pennsylvania, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X153678
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http://dx.doi.org/10.1038/jid.2014.1DOI Listing
May 2014

A promoter-level mammalian expression atlas.

Authors:
Alistair R R Forrest Hideya Kawaji Michael Rehli J Kenneth Baillie Michiel J L de Hoon Vanja Haberle Timo Lassmann Ivan V Kulakovskiy Marina Lizio Masayoshi Itoh Robin Andersson Christopher J Mungall Terrence F Meehan Sebastian Schmeier Nicolas Bertin Mette Jørgensen Emmanuel Dimont Erik Arner Christian Schmidl Ulf Schaefer Yulia A Medvedeva Charles Plessy Morana Vitezic Jessica Severin Colin A Semple Yuri Ishizu Robert S Young Margherita Francescatto Intikhab Alam Davide Albanese Gabriel M Altschuler Takahiro Arakawa John A C Archer Peter Arner Magda Babina Sarah Rennie Piotr J Balwierz Anthony G Beckhouse Swati Pradhan-Bhatt Judith A Blake Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher A Maxwell Burroughs Andrea Califano Carlo V Cannistraci Daniel Carbajo Yun Chen Marco Chierici Yari Ciani Hans C Clevers Emiliano Dalla Carrie A Davis Michael Detmar Alexander D Diehl Taeko Dohi Finn Drabløs Albert S B Edge Matthias Edinger Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Michela Fagiolini Lynsey Fairbairn Hai Fang Mary C Farach-Carson Geoffrey J Faulkner Alexander V Favorov Malcolm E Fisher Martin C Frith Rie Fujita Shiro Fukuda Cesare Furlanello Masaaki Furino Jun-ichi Furusawa Teunis B Geijtenbeek Andrew P Gibson Thomas Gingeras Daniel Goldowitz Julian Gough Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Matthias Harbers Jayson Harshbarger Akira Hasegawa Yuki Hasegawa Takehiro Hashimoto Meenhard Herlyn Kelly J Hitchens Shannan J Ho Sui Oliver M Hofmann Ilka Hoof Furni Hori Lukasz Huminiecki Kei Iida Tomokatsu Ikawa Boris R Jankovic Hui Jia Anagha Joshi Giuseppe Jurman Bogumil Kaczkowski Chieko Kai Kaoru Kaida Ai Kaiho Kazuhiro Kajiyama Mutsumi Kanamori-Katayama Artem S Kasianov Takeya Kasukawa Shintaro Katayama Sachi Kato Shuji Kawaguchi Hiroshi Kawamoto Yuki I Kawamura Tsugumi Kawashima Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura S Peter Klinken Alan J Knox Miki Kojima Soichi Kojima Naoto Kondo Haruhiko Koseki Shigeo Koyasu Sarah Krampitz Atsutaka Kubosaki Andrew T Kwon Jeroen F J Laros Weonju Lee Andreas Lennartsson Kang Li Berit Lilje Leonard Lipovich Alan Mackay-Sim Ri-ichiroh Manabe Jessica C Mar Benoit Marchand Anthony Mathelier Niklas Mejhert Alison Meynert Yosuke Mizuno David A de Lima Morais Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Efthymios Motakis Hozumi Motohashi Christine L Mummery Mitsuyoshi Murata Sayaka Nagao-Sato Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Kenichi Nakazato Erik van Nimwegen Noriko Ninomiya Hiromi Nishiyori Shohei Noma Shohei Noma Tadasuke Noazaki Soichi Ogishima Naganari Ohkura Hiroko Ohimiya Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Arnab Pain Robert Passier Margaret Patrikakis Helena Persson Silvano Piazza James G D Prendergast Owen J L Rackham Jordan A Ramilowski Mamoon Rashid Timothy Ravasi Patrizia Rizzu Marco Roncador Sugata Roy Morten B Rye Eri Saijyo Antti Sajantila Akiko Saka Shimon Sakaguchi Mizuho Sakai Hiroki Sato Suzana Savvi Alka Saxena Claudio Schneider Erik A Schultes Gundula G Schulze-Tanzil Anita Schwegmann Thierry Sengstag Guojun Sheng Hisashi Shimoji Yishai Shimoni Jay W Shin Christophe Simon Daisuke Sugiyama Takaai Sugiyama Masanori Suzuki Naoko Suzuki Rolf K Swoboda Peter A C 't Hoen Michihira Tagami Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Zuotian Tatum Mark Thompson Hiroo Toyodo Tetsuro Toyoda Elvind Valen Marc van de Wetering Linda M van den Berg Roberto Verado Dipti Vijayan Ilya E Vorontsov Wyeth W Wasserman Shoko Watanabe Christine A Wells Louise N Winteringham Ernst Wolvetang Emily J Wood Yoko Yamaguchi Masayuki Yamamoto Misako Yoneda Yohei Yonekura Shigehiro Yoshida Susan E Zabierowski Peter G Zhang Xiaobei Zhao Silvia Zucchelli Kim M Summers Harukazu Suzuki Carsten O Daub Jun Kawai Peter Heutink Winston Hide Tom C Freeman Boris Lenhard Vladimir B Bajic Martin S Taylor Vsevolod J Makeev Albin Sandelin David A Hume Piero Carninci Yoshihide Hayashizaki

Nature 2014 Mar;507(7493):462-70

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http://dx.doi.org/10.1038/nature13182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529748PMC
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On the TRAIL to overcome BRAF-inhibitor resistance.

J Invest Dermatol 2014 Feb;134(2):315-318

Section of Molecular Dermatology, Medical Faculty Mannheim, Department of Dermatology, Venereology, and Allergology, University Heidelberg, Mannheim, Germany. Electronic address:

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http://dx.doi.org/10.1038/jid.2013.348DOI Listing
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Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2.

Cancer Discov 2013 Dec 8;3(12):1378-93. Epub 2013 Oct 8.

1Tumor Metastasis and Microenvironment Program and 2Molecular and Cellular Oncogenesis Program, The Wistar Institute; 3Abramson Cancer Center, University of Pennsylvania, Philadelphia; 4Lehigh Valley Health Network, Allentown, Pennsylvania; 5The National Institute on Aging, NIH, Baltimore, Maryland; and 6Dana-Farber/Harvard Cancer Center, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918498PMC
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