Publications by authors named "Mee-Hyun Lee"

93Publications

Targeted inhibition of c-MET by podophyllotoxin promotes caspase-dependent apoptosis and suppresses cell growth in gefitinib-resistant non-small cell lung cancer cells.

Phytomedicine 2021 Jan 25;80:153355. Epub 2020 Sep 25.

Department of Pharmacy, College of Pharmacy, Mokpo National University, Jeonnam 58554, Republic of Korea; China-US (Henan) Hormel Cancer Institute, Zhengzhou, Henan, 450008, P.R. China; Department of Biomedicine, Health & Life Convergence Sciences, BK21 Four, College of Pharmacy, Mokpo National University, Jeonnam 58554, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2020.153355DOI Listing
January 2021

Alternative Options for Skin Cancer Therapy via Regulation of AKT and Related Signaling Pathways.

Int J Mol Sci 2020 Sep 18;21(18). Epub 2020 Sep 18.

Department of Pharmacy, College of Pharmacy, Mokpo National University, Jeonnam 58554, Korea.

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http://dx.doi.org/10.3390/ijms21186869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560163PMC
September 2020

Effects of Dimethyl Sulfoxide on the Pluripotency and Differentiation Capacity of Mouse Embryonic Stem Cells.

Cell Reprogram 2020 Oct 16;22(5):244-253. Epub 2020 Sep 16.

Department of Life Sciences and Biotechnology, School of Life Sciences and Biotechnology, Kyungpook National University, Daegu, Korea.

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http://dx.doi.org/10.1089/cell.2020.0006DOI Listing
October 2020

Picropodophyllotoxin, an Epimer of Podophyllotoxin, Causes Apoptosis of Human Esophageal Squamous Cell Carcinoma Cells Through ROS-Mediated JNK/P38 MAPK Pathways.

Int J Mol Sci 2020 Jun 30;21(13). Epub 2020 Jun 30.

Department of Dental Pharmacology, School of Dentistry and Institute of Oral Bioscience, BK21 Plus, Jeonbuk National University, Jeonju 54896, Korea.

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http://dx.doi.org/10.3390/ijms21134640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369713PMC
June 2020

Xanthohumol Inhibits the Growth of Keratin 18-Overexpressed Esophageal Squamous Cell Carcinoma and .

Front Cell Dev Biol 2020 19;8:366. Epub 2020 May 19.

Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.

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http://dx.doi.org/10.3389/fcell.2020.00366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248302PMC
May 2020

Suppression of the solar ultraviolet-induced skin carcinogenesis by TOPK inhibitor HI-TOPK-032.

Oncogene 2020 05 10;39(21):4170-4182. Epub 2020 Apr 10.

The Hormel Institute, University of Minnesota, Austin, MN, 55912, USA.

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http://dx.doi.org/10.1038/s41388-020-1286-4DOI Listing
May 2020

Targeting Opsin4/Melanopsin with a Novel Small Molecule Suppresses PKC/RAF/MEK/ERK Signaling and Inhibits Lung Adenocarcinoma Progression.

Mol Cancer Res 2020 07 8;18(7):1028-1038. Epub 2020 Apr 8.

The Hormel Institute, University of Minnesota, Austin, Minnesota.

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http://dx.doi.org/10.1158/1541-7786.MCR-19-1120DOI Listing
July 2020

Janus kinase 2 inhibition by Licochalcone B suppresses esophageal squamous cell carcinoma growth.

Phytother Res 2020 Aug 6;34(8):2032-2043. Epub 2020 Mar 6.

Department of Pharmacy, College of Pharmacy, Mokpo National University, Muan-gun, Republic of Korea.

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http://dx.doi.org/10.1002/ptr.6661DOI Listing
August 2020

Licochalcone C induces cell cycle G1 arrest and apoptosis in human esophageal squamous carcinoma cells by activation of the ROS/MAPK signaling pathway.

J Chemother 2020 May 3;32(3):132-143. Epub 2020 Feb 3.

Department of Pharmacy, College of Pharmacy, Mokpo National University, Jeonnam, Republic of Korea.

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http://dx.doi.org/10.1080/1120009X.2020.1721175DOI Listing
May 2020

(S)-10-Hydroxycamptothecin Inhibits Esophageal Squamous Cell Carcinoma Growth In Vitro and In Vivo Via Decreasing Topoisomerase I Enzyme Activity.

Cancers (Basel) 2019 Dec 6;11(12). Epub 2019 Dec 6.

Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China.

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http://dx.doi.org/10.3390/cancers11121964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966462PMC
December 2019

Licochalcone H Synthesized by Modifying Structure of Licochalcone C Extracted from Glycyrrhiza inflata Induces Apoptosis of Esophageal Squamous Cell Carcinoma Cells.

Cell Biochem Biophys 2020 Mar 9;78(1):65-76. Epub 2019 Nov 9.

Department of Pharmacy, College of Pharmacy, Mokpo National University, Jeonnam, 58554, Republic of Korea.

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http://dx.doi.org/10.1007/s12013-019-00892-3DOI Listing
March 2020

Dual inhibition of EGFR and MET by Echinatin retards cell growth and induces apoptosis of lung cancer cells sensitive or resistant to gefitinib.

Phytother Res 2020 Feb 7;34(2):388-400. Epub 2019 Nov 7.

Department of Pharmacy, Mokpo National University, Jeonnam, 58554, Republic of Korea.

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http://dx.doi.org/10.1002/ptr.6530DOI Listing
February 2020

Licochalcone B inhibits growth and induces apoptosis of human non-small-cell lung cancer cells by dual targeting of EGFR and MET.

Phytomedicine 2019 Oct 5;63:153014. Epub 2019 Jul 5.

Department of Pharmacy, College of Pharmacy, Mokpo National University, Jeonnam 58554, Republic of Korea; China-US (Henan) Hormel Cancer Institute, Zhengzhou, Henan 450008, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2019.153014DOI Listing
October 2019

Cellular adaptation mediated through Nrf2-induced glutamate cysteine ligase up-regulation against oxidative stress caused by iron overload in β-thalassemia/HbE patients.

Free Radic Res 2019 Jul 4;53(7):791-799. Epub 2019 Jul 4.

e Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology and College of Pharmacy, Seoul National University, South Korea.

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http://dx.doi.org/10.1080/10715762.2019.1632444DOI Listing
July 2019

Cell growth inhibition by 3-deoxysappanchalcone is mediated by directly targeting the TOPK signaling pathway in colon cancer.

Phytomedicine 2019 Aug 31;61:152813. Epub 2018 Dec 31.

Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, P.R. China; China-US (Henan) Hormel Cancer Institute, No.127, Dongming Road, Jinshui District, Zhengzhou, Henan, 450008, China; The Collaborative Innovation Center of Henan Province for Cancer Chemoprevention, Zhengzhou, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09447113183063
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http://dx.doi.org/10.1016/j.phymed.2018.12.036DOI Listing
August 2019

Targeting ROCK/LIMK/cofilin signaling pathway in cancer.

Arch Pharm Res 2019 Jun 27;42(6):481-491. Epub 2019 Apr 27.

China-US (Henan) Hormel Cancer Institute, No.127, Dongming Road, Jinshui District, Zhengzhou, 450008, Henan, China.

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http://dx.doi.org/10.1007/s12272-019-01153-wDOI Listing
June 2019

CRISPR/Cas9 - An evolving biological tool kit for cancer biology and oncology.

NPJ Precis Oncol 2019 18;3. Epub 2019 Mar 18.

1Basic Medical College, Zhengzhou University, 450001 Zhengzhou, Henan China.

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http://dx.doi.org/10.1038/s41698-019-0080-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423228PMC
March 2019

Lin28a expression protects against streptozotocin-induced β-cell destruction and prevents diabetes in mice.

Cell Biochem Funct 2019 Apr 18;37(3):139-147. Epub 2019 Mar 18.

Department of Food Science and Nutrition, Kyungpook National University, Sangju, Republic of Korea.

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http://dx.doi.org/10.1002/cbf.3376DOI Listing
April 2019

Correction: 4-Hydroxyestradiol induces mammary epithelial cell transformation through Nrf2-mediated heme oxygenase-1 overexpression.

Oncotarget 2019 02 8;10(12):1266. Epub 2019 Feb 8.

Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, South Korea.

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http://dx.doi.org/10.18632/oncotarget.26681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383815PMC
February 2019

AKT as a Therapeutic Target for Cancer.

Cancer Res 2019 03 26;79(6):1019-1031. Epub 2019 Feb 26.

Basic Medical College, Zhengzhou University, Zhengzhou, Henan, China.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-18-2738DOI Listing
March 2019

p21 Regulation by hYSK1 Activates SP-1 Transcription Factor and Increases MMP-2 Expression under Hypoxic Conditions.

Int J Mol Sci 2019 Jan 14;20(2). Epub 2019 Jan 14.

Department of Pharmaceutical Science & Engineering, Seowon University, Cheongju 28674, Korea.

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http://dx.doi.org/10.3390/ijms20020310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359055PMC
January 2019

JAK2 regulation by licochalcone H inhibits the cell growth and induces apoptosis in oral squamous cell carcinoma.

Phytomedicine 2019 Jan 18;52:60-69. Epub 2018 Sep 18.

Department of Pharmacy, College of Pharmacy and Natural Medicine Research Institute, Mokpo National University, Jeonnam 58554, Republic of Korea; The China-US (Henan) Hormel Cancer Institute, Zhengzhou, Henan 450008, P.R. China. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2018.09.180DOI Listing
January 2019

PIM Kinase as an Executional Target in Cancer.

J Cancer Prev 2018 Sep 30;23(3):109-116. Epub 2018 Sep 30.

Department of Breast Surgery, Breast Cancer Center, Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China.

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http://www.jcpjournal.org/journal/view.html?doi=10.15430/JCP
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http://dx.doi.org/10.15430/JCP.2018.23.3.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197848PMC
September 2018

Licochalcone C induced apoptosis in human oral squamous cell carcinoma cells by regulation of the JAK2/STAT3 signaling pathway.

J Cell Biochem 2018 12 20;119(12):10118-10130. Epub 2018 Aug 20.

Department of Dental Pharmacology, School of Dentistry and Institute of Oral Bioscience, BK21 Plus, Chonbuk National University, Jeonju, Republic of Korea.

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http://doi.wiley.com/10.1002/jcb.27349
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http://dx.doi.org/10.1002/jcb.27349DOI Listing
December 2018

Licochalcone D directly targets JAK2 to induced apoptosis in human oral squamous cell carcinoma.

J Cell Physiol 2019 02 2;234(2):1780-1793. Epub 2018 Aug 2.

Department of Pharmacy, College of Pharmacy and Natural Medicine Research Institute, Mokpo National University, Muan County, Republic of Korea.

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http://dx.doi.org/10.1002/jcp.27050DOI Listing
February 2019

Oridonin induces apoptosis in oral squamous cell carcinoma probably through the generation of reactive oxygen species and the p38/JNK MAPK pathway.

Int J Oncol 2018 May 16;52(5):1749-1759. Epub 2018 Mar 16.

Department of Pharmacy, College of Pharmacy and Natural Medicine Research Institute, Mokpo National University, Jeonnam 58554, Republic of Korea.

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http://www.spandidos-publications.com/10.3892/ijo.2018.4319
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http://dx.doi.org/10.3892/ijo.2018.4319DOI Listing
May 2018

High Salt Intake Attenuates Breast Cancer Metastasis to Lung.

J Agric Food Chem 2018 Apr 22;66(13):3386-3392. Epub 2018 Mar 22.

State Key Laboratory of Food Science and Technology , Jiangnan University , Wuxi 214122 , China.

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http://pubs.acs.org/doi/10.1021/acs.jafc.7b05923
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http://dx.doi.org/10.1021/acs.jafc.7b05923DOI Listing
April 2018

Kaempferol targeting on the fibroblast growth factor receptor 3-ribosomal S6 kinase 2 signaling axis prevents the development of rheumatoid arthritis.

Cell Death Dis 2018 03 14;9(3):401. Epub 2018 Mar 14.

Integrated Research Institute of Pharmaceutical Sciences & BK21 PLUS Team for Creative Leader Program for Pharmacomics-based Future Pharmacy, College of Pharmacy, The Catholic University of Korea, 43, Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do, 420-743, Republic of Korea.

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http://dx.doi.org/10.1038/s41419-018-0433-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851988PMC
March 2018

Editorial: Recent Advances in the Field of Kinases and Kinase Inhibitors.

Curr Pharm Des 2017 11;23(29):4207-4208

China-US (Henan) Hormel Cancer Institute, No 127, Dongming Road, Zhengzhou, Henan, 450008, China.

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http://www.eurekaselect.com/157217/article
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http://dx.doi.org/10.2174/138161282329171116095519DOI Listing
November 2017

hYSK1 promotes cancer cell proliferation and migration through negative regulation of p16 under hypoxic conditions.

Oncotarget 2017 Oct 6;8(51):89072-89085. Epub 2017 Oct 6.

Department of Pharmaceutical Science & Engineering, Seowon University, Cheongju 28674, South Korea.

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http://dx.doi.org/10.18632/oncotarget.21654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687670PMC
October 2017

A Small Molecule Inhibitor of the β-Catenin-TCF4 Interaction Suppresses Colorectal Cancer Growth In Vitro and In Vivo.

EBioMedicine 2017 Nov 27;25:22-31. Epub 2017 Sep 27.

The Hormel Institute, University of Minnesota, Austin, MN 55912, USA; Program in Bioinformatics and Computational Biology, University of Minnesota, Minneapolis, MN 55455, USA; The China-US (Henan) Hormel Cancer Institute, Zhengzhou, Henan, China; The Pathophysiology Department, The School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China; The Collaborative Innovation Center of Henan Province for Cancer Chemoprevention, Zhengzhou, China; The Affiliated Cancer Hospital, Zhengzhou University, Zhengzhou, Henan, China. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.09.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704052PMC
November 2017

LTA4H regulates cell cycle and skin carcinogenesis.

Carcinogenesis 2017 07;38(7):728-737

The Hormel Institute, University of Minnesota, 801 16th Ave. NE, Austin, MN 55912, USA.

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http://dx.doi.org/10.1093/carcin/bgx049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248358PMC
July 2017

Chemoprevention of Colorectal Cancer by Artocarpin, a Dietary Phytochemical from Artocarpus heterophyllus.

J Agric Food Chem 2017 May 18;65(17):3474-3480. Epub 2017 Apr 18.

School of Food Science and Technology, Jiangnan University , Wuxi 214122, China.

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http://dx.doi.org/10.1021/acs.jafc.7b00278DOI Listing
May 2017

4-Hydroxyestradiol induces mammary epithelial cell transformation through Nrf2-mediated heme oxygenase-1 overexpression.

Oncotarget 2017 Jan;8(1):164-178

Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, South Korea.

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http://dx.doi.org/10.18632/oncotarget.10516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352084PMC
January 2017

Implications of Genetic and Epigenetic Alterations of CDKN2A (p16(INK4a)) in Cancer.

EBioMedicine 2016 Jun 3;8:30-39. Epub 2016 May 3.

China-US (Henan) Hormel Cancer Institute, No.127, Dongming Road, Jinshui District, Zhengzhou, Henan 450008, China; The Hormel Institute, University of Minnesota, Austin, MN 55912, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2016.04.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919535PMC
June 2016

Manumycin A induces apoptosis in malignant pleural mesothelioma through regulation of Sp1 and activation of the mitochondria-related apoptotic pathway.

Oncol Rep 2016 Jul 10;36(1):117-24. Epub 2016 May 10.

Department of Pharmacy, College of Pharmacy and Natural Medicine Research Institute, Mokpo National University, Jeonnam 534-729, Republic of Korea.

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http://dx.doi.org/10.3892/or.2016.4801DOI Listing
July 2016

Naringenin targets ERK2 and suppresses UVB-induced photoaging.

J Cell Mol Med 2016 May 10;20(5):909-19. Epub 2016 Feb 10.

The Hormel Institute, University of Minnesota, Minnesota, MN, USA.

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http://dx.doi.org/10.1111/jcmm.12780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831363PMC
May 2016

Licochalcone B induces apoptosis of human oral squamous cell carcinoma through the extrinsic- and intrinsic-signaling pathways.

Int J Oncol 2016 Apr 1;48(4):1749-57. Epub 2016 Feb 1.

Department of Pharmacy, College of Pharmacy and Natural Medicine Research Institute, Mokpo National University, Jeonnam 534-729, Republic of Korea.

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http://dx.doi.org/10.3892/ijo.2016.3365DOI Listing
April 2016

Magnolin inhibits cell migration and invasion by targeting the ERKs/RSK2 signaling pathway.

BMC Cancer 2015 Aug 8;15:576. Epub 2015 Aug 8.

College of Pharmacy, The Catholic University of Korea, 43, Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do, 420-743, Republic of Korea.

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http://bmccancer.biomedcentral.com/articles/10.1186/s12885-0
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http://dx.doi.org/10.1186/s12885-015-1580-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529708PMC
August 2015

Aschantin targeting on the kinase domain of mammalian target of rapamycin suppresses epidermal growth factor-induced neoplastic cell transformation.

Carcinogenesis 2015 Oct 4;36(10):1223-34. Epub 2015 Aug 4.

College of Pharmacy, The Catholic University of Korea, 43, Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do 420-743, Republic of Korea,

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http://dx.doi.org/10.1093/carcin/bgv113DOI Listing
October 2015

Resveratrol Inhibits IL-6-Induced Transcriptional Activity of AR and STAT3 in Human Prostate Cancer LNCaP-FGC Cells.

Biomol Ther (Seoul) 2014 Sep 30;22(5):426-30. Epub 2014 Sep 30.

Pharmaceutical Science and Engineering, School of Convergence Bioscience and Technology, Seowon University, Cheongju 361-742, Republic of Korea.

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http://dx.doi.org/10.4062/biomolther.2014.061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201228PMC
September 2014

The ginsenoside 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol induces autophagy and apoptosis in human melanoma via AMPK/JNK phosphorylation.

PLoS One 2014 19;9(8):e104305. Epub 2014 Aug 19.

WCU Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea; Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of Korea; Research Institute of Bio Food Industry, Institute of Green Bio Science and Technology, Seoul National University, Pyeongchang, Republic of Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104305PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138097PMC
October 2015

Butein, a novel dual inhibitor of MET and EGFR, overcomes gefitinib-resistant lung cancer growth.

Mol Carcinog 2015 Apr 29;54(4):322-31. Epub 2014 Jun 29.

The Hormel Institute, University of Minnesota, Austin, Minnesota; Department of Agricultural Biotechnology, Seoul National University, Seoul, Republic of Korea; Functional Food Resources Research Group, Korea Food Research Institute, Seongnam, Republic of Korea.

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http://dx.doi.org/10.1002/mc.22191DOI Listing
April 2015

ERK1 phosphorylates Nanog to regulate protein stability and stem cell self-renewal.

Stem Cell Res 2014 Jul 13;13(1):1-11. Epub 2014 Apr 13.

The Hormel Institute, University of Minnesota, 801, 16th AVE, NE, Austin, MN 55912, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S18735061140003
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http://dx.doi.org/10.1016/j.scr.2014.04.001DOI Listing
July 2014

Sulforaphane inhibits phorbol ester-stimulated IKK-NF-κB signaling and COX-2 expression in human mammary epithelial cells by targeting NF-κB activating kinase and ERK.

Cancer Lett 2014 Aug 18;351(1):41-9. Epub 2014 Apr 18.

Research Institute for Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, South Korea; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 151-742, South Korea; Cancer Research Institute, Seoul National University, Seoul, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.03.037DOI Listing
August 2014

Licochalcone A, a natural inhibitor of c-Jun N-terminal kinase 1.

Cancer Prev Res (Phila) 2014 Jan 19;7(1):139-49. Epub 2013 Nov 19.

The Hormel Institute University of Minnesota, 801 16 Ave NE, Austin, MN 55912.

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http://dx.doi.org/10.1158/1940-6207.CAPR-13-0117DOI Listing
January 2014

TRAF4 is a critical molecule for Akt activation in lung cancer.

Cancer Res 2013 Dec 23;73(23):6938-50. Epub 2013 Oct 23.

Authors' Affiliations: The Hormel Institute, University of Minnesota, Austin, Minnesota; Cancer Research Institute, Xiangya School of Medicine; Xiangya Hospital, Central South University, Changsha, Hunan; The First Affiliated Hospital; and Physiology and Pathophysiology, Basic Medical School, Zhengzhou University, Zhengzhou, Henan, China.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856436PMC
December 2013

RSK2-induced stress tolerance enhances cell survival signals mediated by inhibition of GSK3β activity.

Biochem Biophys Res Commun 2013 Oct 17;440(1):112-8. Epub 2013 Sep 17.

Integrated Research Institute of Pharmaceutical Sciencies, College of Pharmacy, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do 420-743, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2013.09.042DOI Listing
October 2013

Targeting of magnolin on ERKs inhibits Ras/ERKs/RSK2-signaling-mediated neoplastic cell transformation.

Carcinogenesis 2014 Feb 12;35(2):432-41. Epub 2013 Sep 12.

Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do 420-743, Republic of Korea.

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http://dx.doi.org/10.1093/carcin/bgt306DOI Listing
February 2014

The P110 subunit of PI3-K is a therapeutic target of acacetin in skin cancer.

Carcinogenesis 2014 Jan 2;35(1):123-30. Epub 2013 Aug 2.

The Hormel Institute, University of Minnesota, 801 16th Ave NE, Austin, MN 55912, USA.

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http://dx.doi.org/10.1093/carcin/bgt266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895936PMC
January 2014

CInQ-03, a novel allosteric MEK inhibitor, suppresses cancer growth in vitro and in vivo.

Carcinogenesis 2013 May 25;34(5):1134-43. Epub 2013 Jan 25.

The Hormel Institute, University of Minnesota, Austin, MN 55912, USA.

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http://dx.doi.org/10.1093/carcin/bgt015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643416PMC
May 2013

RSK2 as a key regulator in human skin cancer.

Carcinogenesis 2012 Dec 23;33(12):2529-37. Epub 2012 Aug 23.

Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, 43, Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do 420-743, Republic of Korea.

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http://dx.doi.org/10.1093/carcin/bgs271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510733PMC
December 2012

The role of heterodimeric AP-1 protein comprised of JunD and c-Fos proteins in hematopoiesis.

J Biol Chem 2012 Sep 20;287(37):31342-8. Epub 2012 Jul 20.

Hormel Institute, University of Minnesota, Austin, Minnesota 55912, USA.

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http://dx.doi.org/10.1074/jbc.M112.387266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438963PMC
September 2012

Novel TOPK inhibitor HI-TOPK-032 effectively suppresses colon cancer growth.

Cancer Res 2012 Jun 20;72(12):3060-8. Epub 2012 Apr 20.

The Hormel Institute, University of Minnesota, Minneapolis, Minnesota 55912, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3851DOI Listing
June 2012

Embryonic stem-cell-preconditioned microenvironment induces loss of cancer cell properties in human melanoma cells.

Pigment Cell Melanoma Res 2011 Oct 16;24(5):922-31. Epub 2011 Aug 16.

The Hormel Institute, University of Minnesota, Austin, MN, USA.

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http://dx.doi.org/10.1111/j.1755-148X.2011.00891.xDOI Listing
October 2011

Resveratrol suppresses growth of human ovarian cancer cells in culture and in a murine xenograft model: eukaryotic elongation factor 1A2 as a potential target.

Cancer Res 2009 Sep 8;69(18):7449-58. Epub 2009 Sep 8.

Department of Pharmacy, College of Pharmacy, and Cancer Research Institute, Seoul National University, Seoul, South Korea.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-1266DOI Listing
September 2009

eEF1A2 as a putative oncogene.

Ann N Y Acad Sci 2009 Aug;1171:87-93

National Research Laboratory of Molecular Carcinogenesis and Chemoprevention, College of Pharmacy and Cancer Research Institute, Seoul National University, Seoul, Korea.

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http://dx.doi.org/10.1111/j.1749-6632.2009.04909.xDOI Listing
August 2009

Role of aspartate 351 in transactivation and active conformation of estrogen receptor alpha.

J Mol Endocrinol 2005 Dec;35(3):449-64

Department of Pathology, University of Southern California, Los Angeles, 90089, USA.

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http://dx.doi.org/10.1677/jme.1.01846DOI Listing
December 2005

Syntheses of sphingosine-1-phosphate analogues and their interaction with EDG/S1P receptors.

Bioorg Med Chem Lett 2004 May;14(10):2499-503

Division of Molecular and Life Sciences, Pohang University of Science and Technology, San31, Hyoja-Dong, Nam-gu, Pohang 790-784, South Korea.

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http://dx.doi.org/10.1016/j.bmcl.2004.03.001DOI Listing
May 2004