Medea Imboden

Medea Imboden

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Medea Imboden

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Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Authors:
Nick Shrine Anna L Guyatt A Mesut Erzurumluoglu Victoria E Jackson Brian D Hobbs Carl A Melbourne Chiara Batini Katherine A Fawcett Kijoung Song Phuwanat Sakornsakolpat Xingnan Li Ruth Boxall Nicola F Reeve Ma'en Obeidat Jing Hua Zhao Matthias Wielscher Stefan Weiss Katherine A Kentistou James P Cook Benjamin B Sun Jian Zhou Jennie Hui Stefan Karrasch Medea Imboden Sarah E Harris Jonathan Marten Stefan Enroth Shona M Kerr Ida Surakka Veronique Vitart Terho Lehtimäki Richard J Allen Per S Bakke Terri H Beaty Eugene R Bleecker Yohan Bossé Corry-Anke Brandsma Zhengming Chen James D Crapo John Danesh Dawn L DeMeo Frank Dudbridge Ralf Ewert Christian Gieger Amund Gulsvik Anna L Hansell Ke Hao Joshua D Hoffman John E Hokanson Georg Homuth Peter K Joshi Philippe Joubert Claudia Langenberg Xuan Li Liming Li Kuang Lin Lars Lind Nicholas Locantore Jian'an Luan Anubha Mahajan Joseph C Maranville Alison Murray David C Nickle Richard Packer Margaret M Parker Megan L Paynton David J Porteous Dmitry Prokopenko Dandi Qiao Rajesh Rawal Heiko Runz Ian Sayers Don D Sin Blair H Smith María Soler Artigas David Sparrow Ruth Tal-Singer Paul R H J Timmers Maarten Van den Berge John C Whittaker Prescott G Woodruff Laura M Yerges-Armstrong Olga G Troyanskaya Olli T Raitakari Mika Kähönen Ozren Polašek Ulf Gyllensten Igor Rudan Ian J Deary Nicole M Probst-Hensch Holger Schulz Alan L James James F Wilson Beate Stubbe Eleftheria Zeggini Marjo-Riitta Jarvelin Nick Wareham Edwin K Silverman Caroline Hayward Andrew P Morris Adam S Butterworth Robert A Scott Robin G Walters Deborah A Meyers Michael H Cho David P Strachan Ian P Hall Martin D Tobin Louise V Wain

Nat Genet 2019 Jun;51(6):1067

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/s41588-019-0438-3DOI Listing
June 2019

The mediating effect of immune markers on the association between ambient air pollution and adult-onset asthma.

Sci Rep 2019 Jun 19;9(1):8818. Epub 2019 Jun 19.

Division of Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht University, 3584 CM, Utrecht, the Netherlands.

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http://dx.doi.org/10.1038/s41598-019-45327-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584571PMC
June 2019

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Authors:
Nick Shrine Anna L Guyatt A Mesut Erzurumluoglu Victoria E Jackson Brian D Hobbs Carl A Melbourne Chiara Batini Katherine A Fawcett Kijoung Song Phuwanat Sakornsakolpat Xingnan Li Ruth Boxall Nicola F Reeve Ma'en Obeidat Jing Hua Zhao Matthias Wielscher Stefan Weiss Katherine A Kentistou James P Cook Benjamin B Sun Jian Zhou Jennie Hui Stefan Karrasch Medea Imboden Sarah E Harris Jonathan Marten Stefan Enroth Shona M Kerr Ida Surakka Veronique Vitart Terho Lehtimäki Richard J Allen Per S Bakke Terri H Beaty Eugene R Bleecker Yohan Bossé Corry-Anke Brandsma Zhengming Chen James D Crapo John Danesh Dawn L DeMeo Frank Dudbridge Ralf Ewert Christian Gieger Amund Gulsvik Anna L Hansell Ke Hao Joshua D Hoffman John E Hokanson Georg Homuth Peter K Joshi Philippe Joubert Claudia Langenberg Xuan Li Liming Li Kuang Lin Lars Lind Nicholas Locantore Jian'an Luan Anubha Mahajan Joseph C Maranville Alison Murray David C Nickle Richard Packer Margaret M Parker Megan L Paynton David J Porteous Dmitry Prokopenko Dandi Qiao Rajesh Rawal Heiko Runz Ian Sayers Don D Sin Blair H Smith María Soler Artigas David Sparrow Ruth Tal-Singer Paul R H J Timmers Maarten Van den Berge John C Whittaker Prescott G Woodruff Laura M Yerges-Armstrong Olga G Troyanskaya Olli T Raitakari Mika Kähönen Ozren Polašek Ulf Gyllensten Igor Rudan Ian J Deary Nicole M Probst-Hensch Holger Schulz Alan L James James F Wilson Beate Stubbe Eleftheria Zeggini Marjo-Riitta Jarvelin Nick Wareham Edwin K Silverman Caroline Hayward Andrew P Morris Adam S Butterworth Robert A Scott Robin G Walters Deborah A Meyers Michael H Cho David P Strachan Ian P Hall Martin D Tobin Louise V Wain

Nat Genet 2019 03 25;51(3):481-493. Epub 2019 Feb 25.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/s41588-018-0321-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397078PMC
March 2019

Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Nat Genet 2018 09;50(9):1343

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41588-018-0197-6DOI Listing
September 2018

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Nat Genet 2018 08 16;50(8):1072-1080. Epub 2018 Jul 16.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41588-018-0157-1DOI Listing
August 2018

Alpha-1 antitrypsin deficiency: From the lung to the heart?

Atherosclerosis 2018 03 31;270:166-172. Epub 2018 Jan 31.

Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.01.042DOI Listing
March 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Authors:
Florence Demenais Patricia Margaritte-Jeannin Kathleen C Barnes William O C Cookson Janine Altmüller Wei Ang R Graham Barr Terri H Beaty Allan B Becker John Beilby Hans Bisgaard Unnur Steina Bjornsdottir Eugene Bleecker Klaus Bønnelykke Dorret I Boomsma Emmanuelle Bouzigon Christopher E Brightling Myriam Brossard Guy G Brusselle Esteban Burchard Kristin M Burkart Andrew Bush Moira Chan-Yeung Kian Fan Chung Alexessander Couto Alves John A Curtin Adnan Custovic Denise Daley Johan C de Jongste Blanca E Del-Rio-Navarro Kathleen M Donohue Liesbeth Duijts Celeste Eng Johan G Eriksson Martin Farrall Yuliya Fedorova Bjarke Feenstra Manuel A Ferreira Maxim B Freidin Zofia Gajdos Jim Gauderman Ulrike Gehring Frank Geller Jon Genuneit Sina A Gharib Frank Gilliland Raquel Granell Penelope E Graves Daniel F Gudbjartsson Tari Haahtela Susan R Heckbert Dick Heederik Joachim Heinrich Markku Heliövaara John Henderson Blanca E Himes Hiroshi Hirose Joel N Hirschhorn Albert Hofman Patrick Holt Jouke Hottenga Thomas J Hudson Jennie Hui Medea Imboden Vladimir Ivanov Vincent W V Jaddoe Alan James Christer Janson Marjo-Riitta Jarvelin Deborah Jarvis Graham Jones Ingileif Jonsdottir Pekka Jousilahti Michael Kabesch Mika Kähönen David B Kantor Alexandra S Karunas Elza Khusnutdinova Gerard H Koppelman Anita L Kozyrskyj Eskil Kreiner Michiaki Kubo Rajesh Kumar Ashish Kumar Mikko Kuokkanen Lies Lahousse Tarja Laitinen Catherine Laprise Mark Lathrop Susanne Lau Young-Ae Lee Terho Lehtimäki Sébastien Letort Albert M Levin Guo Li Liming Liang Laura R Loehr Stephanie J London Daan W Loth Ani Manichaikul Ingo Marenholz Fernando J Martinez Melanie C Matheson Rasika A Mathias Kenji Matsumoto Hamdi Mbarek Wendy L McArdle Mads Melbye Erik Melén Deborah Meyers Sven Michel Hamida Mohamdi Arthur W Musk Rachel A Myers Maartje A E Nieuwenhuis Emiko Noguchi George T O'Connor Ludmila M Ogorodova Cameron D Palmer Aarno Palotie Julie E Park Craig E Pennell Göran Pershagen Alexey Polonikov Dirkje S Postma Nicole Probst-Hensch Valery P Puzyrev Benjamin A Raby Olli T Raitakari Adaikalavan Ramasamy Stephen S Rich Colin F Robertson Isabelle Romieu Muhammad T Salam Veikko Salomaa Vivi Schlünssen Robert Scott Polina A Selivanova Torben Sigsgaard Angela Simpson Valérie Siroux Lewis J Smith Maria Solodilova Marie Standl Kari Stefansson David P Strachan Bruno H Stricker Atsushi Takahashi Philip J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Carla M T Tiesler Dara G Torgerson Tatsuhiko Tsunoda André G Uitterlinden Ralf J P van der Valk Amaury Vaysse Sailaja Vedantam Andrea von Berg Erika von Mutius Judith M Vonk Johannes Waage Nick J Wareham Scott T Weiss Wendy B White Magnus Wickman Elisabeth Widén Gonneke Willemsen L Keoki Williams Inge M Wouters James J Yang Jing Hua Zhao Miriam F Moffatt Carole Ober Dan L Nicolae

Nat Genet 2018 01 22;50(1):42-53. Epub 2017 Dec 22.

Departments of Statistics, Human Genetics and Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.

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http://www.nature.com/articles/s41588-017-0014-7
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http://dx.doi.org/10.1038/s41588-017-0014-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901974PMC
January 2018

Meta-analysis of exome array data identifies six novel genetic loci for lung function.

Authors:
Victoria E Jackson Jeanne C Latourelle Louise V Wain Albert V Smith Megan L Grove Traci M Bartz Ma'en Obeidat Michael A Province Wei Gao Beenish Qaiser David J Porteous Patricia A Cassano Tarunveer S Ahluwalia Niels Grarup Jin Li Elisabeth Altmaier Jonathan Marten Sarah E Harris Ani Manichaikul Tess D Pottinger Ruifang Li-Gao Allan Lind-Thomsen Anubha Mahajan Lies Lahousse Medea Imboden Alexander Teumer Bram Prins Leo-Pekka Lyytikäinen Gudny Eiriksdottir Nora Franceschini Colleen M Sitlani Jennifer A Brody Yohan Bossé Wim Timens Aldi Kraja Anu Loukola Wenbo Tang Yongmei Liu Jette Bork-Jensen Johanne M Justesen Allan Linneberg Leslie A Lange Rajesh Rawal Stefan Karrasch Jennifer E Huffman Blair H Smith Gail Davies Kristin M Burkart Josyf C Mychaleckyj Tobias N Bonten Stefan Enroth Lars Lind Guy G Brusselle Ashish Kumar Beate Stubbe Mika Kähönen Annah B Wyss Bruce M Psaty Susan R Heckbert Ke Hao Taina Rantanen Stephen B Kritchevsky Kurt Lohman Tea Skaaby Charlotta Pisinger Torben Hansen Holger Schulz Ozren Polasek Archie Campbell John M Starr Stephen S Rich Dennis O Mook-Kanamori Åsa Johansson Erik Ingelsson André G Uitterlinden Stefan Weiss Olli T Raitakari Vilmundur Gudnason Kari E North Sina A Gharib Don D Sin Kent D Taylor George T O'Connor Jaakko Kaprio Tamara B Harris Oluf Pederson Henrik Vestergaard James G Wilson Konstantin Strauch Caroline Hayward Shona Kerr Ian J Deary R Graham Barr Renée de Mutsert Ulf Gyllensten Andrew P Morris M Arfan Ikram Nicole Probst-Hensch Sven Gläser Eleftheria Zeggini Terho Lehtimäki David P Strachan Josée Dupuis Alanna C Morrison Ian P Hall Martin D Tobin Stephanie J London

Wellcome Open Res 2018 12;3. Epub 2018 Jan 12.

Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Dept of Health and Human Services, Research Triangle Park, NC, 27709, USA.

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http://dx.doi.org/10.12688/wellcomeopenres.12583.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081985PMC
January 2018

Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.

Authors:
Mathias Gorski Peter J van der Most Alexander Teumer Audrey Y Chu Man Li Vladan Mijatovic Ilja M Nolte Massimiliano Cocca Daniel Taliun Felicia Gomez Yong Li Bamidele Tayo Adrienne Tin Mary F Feitosa Thor Aspelund John Attia Reiner Biffar Murielle Bochud Eric Boerwinkle Ingrid Borecki Erwin P Bottinger Ming-Huei Chen Vincent Chouraki Marina Ciullo Josef Coresh Marilyn C Cornelis Gary C Curhan Adamo Pio d' Adamo Abbas Dehghan Laura Dengler Jingzhong Ding Gudny Eiriksdottir Karlhans Endlich Stefan Enroth Tõnu Esko Oscar H Franco Paolo Gasparini Christian Gieger Giorgia Girotto Omri Gottesman Vilmundur Gudnason Ulf Gyllensten Stephen J Hancock Tamara B Harris Catherine Helmer Simon Höllerer Edith Hofer Albert Hofman Elizabeth G Holliday Georg Homuth Frank B Hu Cornelia Huth Nina Hutri-Kähönen Shih-Jen Hwang Medea Imboden Åsa Johansson Mika Kähönen Wolfgang König Holly Kramer Bernhard K Krämer Ashish Kumar Zoltan Kutalik Jean-Charles Lambert Lenore J Launer Terho Lehtimäki Martin H de Borst Gerjan Navis Morris Swertz Yongmei Liu Kurt Lohman Ruth J F Loos Yingchang Lu Leo-Pekka Lyytikäinen Mark A McEvoy Christa Meisinger Thomas Meitinger Andres Metspalu Marie Metzger Evelin Mihailov Paul Mitchell Matthias Nauck Albertine J Oldehinkel Matthias Olden Brenda Wjh Penninx Giorgio Pistis Peter P Pramstaller Nicole Probst-Hensch Olli T Raitakari Rainer Rettig Paul M Ridker Fernando Rivadeneira Antonietta Robino Sylvia E Rosas Douglas Ruderfer Daniela Ruggiero Yasaman Saba Cinzia Sala Helena Schmidt Reinhold Schmidt Rodney J Scott Sanaz Sedaghat Albert V Smith Rossella Sorice Benedicte Stengel Sylvia Stracke Konstantin Strauch Daniela Toniolo Andre G Uitterlinden Sheila Ulivi Jorma S Viikari Uwe Völker Peter Vollenweider Henry Völzke Dragana Vuckovic Melanie Waldenberger Jie Jin Wang Qiong Yang Daniel I Chasman Gerard Tromp Harold Snieder Iris M Heid Caroline S Fox Anna Köttgen Cristian Pattaro Carsten A Böger Christian Fuchsberger

Sci Rep 2017 05 26;7:46835. Epub 2017 May 26.

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http://dx.doi.org/10.1038/srep46835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445557PMC
May 2017

Hypertension, diabetes and lifestyle in the long-term - Results from a Swiss population-based cohort.

Prev Med 2017 Apr 21;97:56-61. Epub 2016 Dec 21.

Swiss Tropical and Public Health Institute, Socinstrasse 57, 4051 Basel, Switzerland; University of Basel, Petersplatz 1, 4003 Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ypmed.2016.12.016DOI Listing
April 2017

Heterogeneity of obesity-asthma association disentangled by latent class analysis, the SAPALDIA cohort.

Respir Med 2017 04 20;125:25-32. Epub 2017 Feb 20.

Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2017.02.014DOI Listing
April 2017

1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.

Authors:
Mathias Gorski Peter J van der Most Alexander Teumer Audrey Y Chu Man Li Vladan Mijatovic Ilja M Nolte Massimiliano Cocca Daniel Taliun Felicia Gomez Yong Li Bamidele Tayo Adrienne Tin Mary F Feitosa Thor Aspelund John Attia Reiner Biffar Murielle Bochud Eric Boerwinkle Ingrid Borecki Erwin P Bottinger Ming-Huei Chen Vincent Chouraki Marina Ciullo Josef Coresh Marilyn C Cornelis Gary C Curhan Adamo Pio d'Adamo Abbas Dehghan Laura Dengler Jingzhong Ding Gudny Eiriksdottir Karlhans Endlich Stefan Enroth Tõnu Esko Oscar H Franco Paolo Gasparini Christian Gieger Giorgia Girotto Omri Gottesman Vilmundur Gudnason Ulf Gyllensten Stephen J Hancock Tamara B Harris Catherine Helmer Simon Höllerer Edith Hofer Albert Hofman Elizabeth G Holliday Georg Homuth Frank B Hu Cornelia Huth Nina Hutri-Kähönen Shih-Jen Hwang Medea Imboden Åsa Johansson Mika Kähönen Wolfgang König Holly Kramer Bernhard K Krämer Ashish Kumar Zoltan Kutalik Jean-Charles Lambert Lenore J Launer Terho Lehtimäki Martin de Borst Gerjan Navis Morris Swertz Yongmei Liu Kurt Lohman Ruth J F Loos Yingchang Lu Leo-Pekka Lyytikäinen Mark A McEvoy Christa Meisinger Thomas Meitinger Andres Metspalu Marie Metzger Evelin Mihailov Paul Mitchell Matthias Nauck Albertine J Oldehinkel Matthias Olden Brenda Wjh Penninx Giorgio Pistis Peter P Pramstaller Nicole Probst-Hensch Olli T Raitakari Rainer Rettig Paul M Ridker Fernando Rivadeneira Antonietta Robino Sylvia E Rosas Douglas Ruderfer Daniela Ruggiero Yasaman Saba Cinzia Sala Helena Schmidt Reinhold Schmidt Rodney J Scott Sanaz Sedaghat Albert V Smith Rossella Sorice Benedicte Stengel Sylvia Stracke Konstantin Strauch Daniela Toniolo Andre G Uitterlinden Sheila Ulivi Jorma S Viikari Uwe Völker Peter Vollenweider Henry Völzke Dragana Vuckovic Melanie Waldenberger Jie Jin Wang Qiong Yang Daniel I Chasman Gerard Tromp Harold Snieder Iris M Heid Caroline S Fox Anna Köttgen Cristian Pattaro Carsten A Böger Christian Fuchsberger

Sci Rep 2017 04 28;7:45040. Epub 2017 Apr 28.

Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano, Italy.

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http://dx.doi.org/10.1038/srep45040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408227PMC
April 2017

and Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function.

Authors:
Man Li Yong Li Olivia Weeks Vladan Mijatovic Alexander Teumer Jennifer E Huffman Gerard Tromp Christian Fuchsberger Mathias Gorski Leo-Pekka Lyytikäinen Teresa Nutile Sanaz Sedaghat Rossella Sorice Adrienne Tin Qiong Yang Tarunveer S Ahluwalia Dan E Arking Nathan A Bihlmeyer Carsten A Böger Robert J Carroll Daniel I Chasman Marilyn C Cornelis Abbas Dehghan Jessica D Faul Mary F Feitosa Giovanni Gambaro Paolo Gasparini Franco Giulianini Iris Heid Jinyan Huang Medea Imboden Anne U Jackson Janina Jeff Min A Jhun Ronit Katz Annette Kifley Tuomas O Kilpeläinen Ashish Kumar Markku Laakso Ruifang Li-Gao Kurt Lohman Yingchang Lu Reedik Mägi Giovanni Malerba Evelin Mihailov Karen L Mohlke Dennis O Mook-Kanamori Antonietta Robino Douglas Ruderfer Erika Salvi Ursula M Schick Christina-Alexandra Schulz Albert V Smith Jennifer A Smith Michela Traglia Laura M Yerges-Armstrong Wei Zhao Mark O Goodarzi Aldi T Kraja Chunyu Liu Jennifer Wessel Eric Boerwinkle Ingrid B Borecki Jette Bork-Jensen Erwin P Bottinger Daniele Braga Ivan Brandslund Jennifer A Brody Archie Campbell David J Carey Cramer Christensen Josef Coresh Errol Crook Gary C Curhan Daniele Cusi Ian H de Boer Aiko P J de Vries Joshua C Denny Olivier Devuyst Albert W Dreisbach Karlhans Endlich Tõnu Esko Oscar H Franco Tibor Fulop Glenn S Gerhard Charlotte Glümer Omri Gottesman Niels Grarup Vilmundur Gudnason Torben Hansen Tamara B Harris Caroline Hayward Lynne Hocking Albert Hofman Frank B Hu Lise Lotte N Husemoen Rebecca D Jackson Torben Jørgensen Marit E Jørgensen Mika Kähönen Sharon L R Kardia Wolfgang König Charles Kooperberg Jennifer Kriebel Lenore J Launer Torsten Lauritzen Terho Lehtimäki Daniel Levy Pamela Linksted Allan Linneberg Yongmei Liu Ruth J F Loos Antonio Lupo Christine Meisinger Olle Melander Andres Metspalu Paul Mitchell Matthias Nauck Peter Nürnberg Marju Orho-Melander Afshin Parsa Oluf Pedersen Annette Peters Ulrike Peters Ozren Polasek David Porteous Nicole M Probst-Hensch Bruce M Psaty Lu Qi Olli T Raitakari Alex P Reiner Rainer Rettig Paul M Ridker Fernando Rivadeneira Jacques E Rossouw Frank Schmidt David Siscovick Nicole Soranzo Konstantin Strauch Daniela Toniolo Stephen T Turner André G Uitterlinden Sheila Ulivi Dinesh Velayutham Uwe Völker Henry Völzke Melanie Waldenberger Jie Jin Wang David R Weir Daniel Witte Helena Kuivaniemi Caroline S Fox Nora Franceschini Wolfram Goessling Anna Köttgen Audrey Y Chu

J Am Soc Nephrol 2017 Mar 5;28(3):981-994. Epub 2016 Dec 5.

National Heart, Lung, and Blood Institute's Framingham Heart Study and the Center for Population Studies, Framingham, Massachusetts;

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http://dx.doi.org/10.1681/ASN.2016020131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328154PMC
March 2017

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.

Authors:
Louise V Wain Nick Shrine María Soler Artigas A Mesut Erzurumluoglu Boris Noyvert Lara Bossini-Castillo Ma'en Obeidat Amanda P Henry Michael A Portelli Robert J Hall Charlotte K Billington Tracy L Rimington Anthony G Fenech Catherine John Tineka Blake Victoria E Jackson Richard J Allen Bram P Prins Archie Campbell David J Porteous Marjo-Riitta Jarvelin Matthias Wielscher Alan L James Jennie Hui Nicholas J Wareham Jing Hua Zhao James F Wilson Peter K Joshi Beate Stubbe Rajesh Rawal Holger Schulz Medea Imboden Nicole M Probst-Hensch Stefan Karrasch Christian Gieger Ian J Deary Sarah E Harris Jonathan Marten Igor Rudan Stefan Enroth Ulf Gyllensten Shona M Kerr Ozren Polasek Mika Kähönen Ida Surakka Veronique Vitart Caroline Hayward Terho Lehtimäki Olli T Raitakari David M Evans A John Henderson Craig E Pennell Carol A Wang Peter D Sly Emily S Wan Robert Busch Brian D Hobbs Augusto A Litonjua David W Sparrow Amund Gulsvik Per S Bakke James D Crapo Terri H Beaty Nadia N Hansel Rasika A Mathias Ingo Ruczinski Kathleen C Barnes Yohan Bossé Philippe Joubert Maarten van den Berge Corry-Anke Brandsma Peter D Paré Don D Sin David C Nickle Ke Hao Omri Gottesman Frederick E Dewey Shannon E Bruse David J Carey H Lester Kirchner Stefan Jonsson Gudmar Thorleifsson Ingileif Jonsdottir Thorarinn Gislason Kari Stefansson Claudia Schurmann Girish Nadkarni Erwin P Bottinger Ruth J F Loos Robin G Walters Zhengming Chen Iona Y Millwood Julien Vaucher Om P Kurmi Liming Li Anna L Hansell Chris Brightling Eleftheria Zeggini Michael H Cho Edwin K Silverman Ian Sayers Gosia Trynka Andrew P Morris David P Strachan Ian P Hall Martin D Tobin

Nat Genet 2017 Mar 6;49(3):416-425. Epub 2017 Feb 6.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/ng.3787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326681PMC
March 2017

The adverse impact of obesity on heart rate variability is modified by a NFE2L2 gene variant: The SAPALDIA cohort.

Int J Cardiol 2017 Feb 8;228:341-346. Epub 2016 Nov 8.

Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.11.049DOI Listing
February 2017

Air pollution and diabetes association: Modification by type 2 diabetes genetic risk score.

Environ Int 2016 Sep 6;94:263-271. Epub 2016 Jun 6.

Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2016.04.032DOI Listing
September 2016

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.

Authors:
Cristian Pattaro Alexander Teumer Mathias Gorski Audrey Y Chu Man Li Vladan Mijatovic Maija Garnaas Adrienne Tin Rossella Sorice Yong Li Daniel Taliun Matthias Olden Meredith Foster Qiong Yang Ming-Huei Chen Tune H Pers Andrew D Johnson Yi-An Ko Christian Fuchsberger Bamidele Tayo Michael Nalls Mary F Feitosa Aaron Isaacs Abbas Dehghan Pio d'Adamo Adebowale Adeyemo Aida Karina Dieffenbach Alan B Zonderman Ilja M Nolte Peter J van der Most Alan F Wright Alan R Shuldiner Alanna C Morrison Albert Hofman Albert V Smith Albert W Dreisbach Andre Franke Andre G Uitterlinden Andres Metspalu Anke Tonjes Antonio Lupo Antonietta Robino Åsa Johansson Ayse Demirkan Barbara Kollerits Barry I Freedman Belen Ponte Ben A Oostra Bernhard Paulweber Bernhard K Krämer Braxton D Mitchell Brendan M Buckley Carmen A Peralta Caroline Hayward Catherine Helmer Charles N Rotimi Christian M Shaffer Christian Müller Cinzia Sala Cornelia M van Duijn Aude Saint-Pierre Daniel Ackermann Daniel Shriner Daniela Ruggiero Daniela Toniolo Yingchang Lu Daniele Cusi Darina Czamara David Ellinghaus David S Siscovick Douglas Ruderfer Christian Gieger Harald Grallert Elena Rochtchina Elizabeth J Atkinson Elizabeth G Holliday Eric Boerwinkle Erika Salvi Erwin P Bottinger Federico Murgia Fernando Rivadeneira Florian Ernst Florian Kronenberg Frank B Hu Gerjan J Navis Gary C Curhan George B Ehret Georg Homuth Stefan Coassin Gian-Andri Thun Giorgio Pistis Giovanni Gambaro Giovanni Malerba Grant W Montgomery Gudny Eiriksdottir Gunnar Jacobs Guo Li H-Erich Wichmann Harry Campbell Helena Schmidt Henri Wallaschofski Henry Völzke Hermann Brenner Heyo K Kroemer Holly Kramer Honghuang Lin I Mateo Leach Ian Ford Idris Guessous Igor Rudan Inga Prokopenko Ingrid Borecki Iris M Heid Ivana Kolcic Ivana Persico J Wouter Jukema James F Wilson Janine F Felix Jasmin Divers Jean-Charles Lambert Jeanette M Stafford Jean-Michel Gaspoz Jennifer A Smith Jessica D Faul Jie Jin Wang Jingzhong Ding Joel N Hirschhorn John Attia John B Whitfield John Chalmers Jorma Viikari Josef Coresh Joshua C Denny Juha Karjalainen Jyotika K Fernandes Karlhans Endlich Katja Butterbach Keith L Keene Kurt Lohman Laura Portas Lenore J Launer Leo-Pekka Lyytikäinen Loic Yengo Lude Franke Luigi Ferrucci Lynda M Rose Lyudmyla Kedenko Madhumathi Rao Maksim Struchalin Marcus E Kleber Margherita Cavalieri Margot Haun Marilyn C Cornelis Marina Ciullo Mario Pirastu Mariza de Andrade Mark A McEvoy Mark Woodward Martin Adam Massimiliano Cocca Matthias Nauck Medea Imboden Melanie Waldenberger Menno Pruijm Marie Metzger Michael Stumvoll Michele K Evans Michele M Sale Mika Kähönen Mladen Boban Murielle Bochud Myriam Rheinberger Niek Verweij Nabila Bouatia-Naji Nicholas G Martin Nick Hastie Nicole Probst-Hensch Nicole Soranzo Olivier Devuyst Olli Raitakari Omri Gottesman Oscar H Franco Ozren Polasek Paolo Gasparini Patricia B Munroe Paul M Ridker Paul Mitchell Paul Muntner Christa Meisinger Johannes H Smit Peter Kovacs Philipp S Wild Philippe Froguel Rainer Rettig Reedik Mägi Reiner Biffar Reinhold Schmidt Rita P S Middelberg Robert J Carroll Brenda W Penninx Rodney J Scott Ronit Katz Sanaz Sedaghat Sarah H Wild Sharon L R Kardia Sheila Ulivi Shih-Jen Hwang Stefan Enroth Stefan Kloiber Stella Trompet Benedicte Stengel Stephen J Hancock Stephen T Turner Sylvia E Rosas Sylvia Stracke Tamara B Harris Tanja Zeller Tatijana Zemunik Terho Lehtimäki Thomas Illig Thor Aspelund Tiit Nikopensius Tonu Esko Toshiko Tanaka Ulf Gyllensten Uwe Völker Valur Emilsson Veronique Vitart Ville Aalto Vilmundur Gudnason Vincent Chouraki Wei-Min Chen Wilmar Igl Winfried März Wolfgang Koenig Wolfgang Lieb Ruth J F Loos Yongmei Liu Harold Snieder Peter P Pramstaller Afshin Parsa Jeffrey R O'Connell Katalin Susztak Pavel Hamet Johanne Tremblay Ian H de Boer Carsten A Böger Wolfram Goessling Daniel I Chasman Anna Köttgen W H Linda Kao Caroline S Fox

Nat Commun 2016 Jan 21;7:10023. Epub 2016 Jan 21.

NHLBI's Framingham Heart Study and the Center for Population Studies, 73 Mt Wayte Avenue, Suite 2, Framingham, Massachusetts 01702, USA.

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http://dx.doi.org/10.1038/ncomms10023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735748PMC
January 2016

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.

Authors:
Lavinia Paternoster Marie Standl Johannes Waage Hansjörg Baurecht Melanie Hotze David P Strachan John A Curtin Klaus Bønnelykke Chao Tian Atsushi Takahashi Jorge Esparza-Gordillo Alexessander Couto Alves Jacob P Thyssen Herman T den Dekker Manuel A Ferreira Elisabeth Altmaier Patrick Ma Sleiman Feng Li Xiao Juan R Gonzalez Ingo Marenholz Birgit Kalb Maria Pino Yanes Cheng-Jian Xu Lisbeth Carstensen Maria M Groen-Blokhuis Cristina Venturini Craig E Pennell Sheila J Barton Albert M Levin Ivan Curjuric Mariona Bustamante Eskil Kreiner-Møller Gabrielle A Lockett Jonas Bacelis Supinda Bunyavanich Rachel A Myers Anja Matanovic Ashish Kumar Joyce Y Tung Tomomitsu Hirota Michiaki Kubo Wendy L McArdle A J Henderson John P Kemp Jie Zheng George Davey Smith Franz Rüschendorf Anja Bauerfeind Min Ae Lee-Kirsch Andreas Arnold Georg Homuth Carsten O Schmidt Elisabeth Mangold Sven Cichon Thomas Keil Elke Rodríguez Annette Peters Andre Franke Wolfgang Lieb Natalija Novak Regina Fölster-Holst Momoko Horikoshi Juha Pekkanen Sylvain Sebert Lise L Husemoen Niels Grarup Johan C de Jongste Fernando Rivadeneira Albert Hofman Vincent Wv Jaddoe Suzanne Gma Pasmans Niels J Elbert André G Uitterlinden Guy B Marks Philip J Thompson Melanie C Matheson Colin F Robertson Janina S Ried Jin Li Xian Bo Zuo Xiao Dong Zheng Xian Yong Yin Liang Dan Sun Maeve A McAleer Grainne M O'Regan Caoimhe Mr Fahy Linda E Campbell Milan Macek Michael Kurek Donglei Hu Celeste Eng Dirkje S Postma Bjarke Feenstra Frank Geller Jouke Jan Hottenga Christel M Middeldorp Pirro Hysi Veronique Bataille Tim Spector Carla Mt Tiesler Elisabeth Thiering Badri Pahukasahasram James J Yang Medea Imboden Scott Huntsman Natàlia Vilor-Tejedor Caroline L Relton Ronny Myhre Wenche Nystad Adnan Custovic Scott T Weiss Deborah A Meyers Cilla Söderhäll Erik Melén Carole Ober Benjamin A Raby Angela Simpson Bo Jacobsson John W Holloway Hans Bisgaard Jordi Sunyer Nicole M Probst Hensch L Keoki Williams Keith M Godfrey Carol A Wang Dorret I Boomsma Mads Melbye Gerard H Koppelman Deborah Jarvis Wh Irwin McLean Alan D Irvine Xue Jun Zhang Hakon Hakonarson Christian Gieger Esteban G Burchard Nicholas G Martin Liesbeth Duijts Allan Linneberg Marjo-Riitta Jarvelin Markus M Noethen Susanne Lau Norbert Hübner Young-Ae Lee Mayumi Tamari David A Hinds Daniel Glass Sara J Brown Joachim Heinrich David M Evans Stephan Weidinger

Nat Genet 2015 Dec 19;47(12):1449-1456. Epub 2015 Oct 19.

Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1038/ng.3424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753676PMC
December 2015

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation.

Nat Commun 2015 Dec 4;6:8658. Epub 2015 Dec 4.

Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Leicester LE1 7RH, UK.

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http://dx.doi.org/10.1038/ncomms9658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686825PMC
December 2015

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function.

PLoS One 2014 1;9(7):e100776. Epub 2014 Jul 1.

Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America; Department of Health Care Policy and Research, Division of Biostatistics and Epidemiology, Weill Cornell Medical College, New York, New York, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077649PMC
November 2015

Long-term air pollution exposure and diabetes in a population-based Swiss cohort.

Environ Int 2014 Sep 7;70:95-105. Epub 2014 Jun 7.

Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2014.05.014DOI Listing
September 2014

Novel childhood asthma genes interact with in utero and early-life tobacco smoke exposure.

J Allergy Clin Immunol 2014 Mar 6;133(3):885-8. Epub 2013 Dec 6.

Department of Epidemiology, University of Groningen, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2013.08.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969577PMC
March 2014

Follow-up on genome-wide main effects: do polymorphisms modify the air pollution effect on lung function decline in adults?

Environ Int 2014 Mar 31;64:110-5. Epub 2013 Dec 31.

Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland. Electronic address:

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March 2014

Prevalence of atopy and respiratory allergic diseases in the elderly SAPALDIA population.

Int Arch Allergy Immunol 2013 31;162(2):143-8. Epub 2013 Jul 31.

Faculty of Medicine, University of Zürich, Zürich, Switzerland.

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December 2013

Common variants in Mendelian kidney disease genes and their association with renal function.

Authors:
Afshin Parsa Christian Fuchsberger Anna Köttgen Conall M O'Seaghdha Cristian Pattaro Mariza de Andrade Daniel I Chasman Alexander Teumer Karlhans Endlich Matthias Olden Ming-Huei Chen Adrienne Tin Young J Kim Daniel Taliun Man Li Mary Feitosa Mathias Gorski Qiong Yang Claudia Hundertmark Meredith C Foster Nicole Glazer Aaron Isaacs Madhumathi Rao Albert V Smith Jeffrey R O'Connell Maksim Struchalin Toshiko Tanaka Guo Li Shih-Jen Hwang Elizabeth J Atkinson Kurt Lohman Marilyn C Cornelis Asa Johansson Anke Tönjes Abbas Dehghan Vincent Couraki Elizabeth G Holliday Rossella Sorice Zoltan Kutalik Terho Lehtimäki Tõnu Esko Harshal Deshmukh Sheila Ulivi Audrey Y Chu Federico Murgia Stella Trompet Medea Imboden Barbara Kollerits Giorgio Pistis Tamara B Harris Lenore J Launer Thor Aspelund Gudny Eiriksdottir Braxton D Mitchell Eric Boerwinkle Helena Schmidt Edith Hofer Frank Hu Ayse Demirkan Ben A Oostra Stephen T Turner Jingzhong Ding Jeanette S Andrews Barry I Freedman Franco Giulianini Wolfgang Koenig Thomas Illig Angela Döring H-Erich Wichmann Lina Zgaga Tatijana Zemunik Mladen Boban Cosetta Minelli Heather E Wheeler Wilmar Igl Ghazal Zaboli Sarah H Wild Alan F Wright Harry Campbell David Ellinghaus Ute Nöthlings Gunnar Jacobs Reiner Biffar Florian Ernst Georg Homuth Heyo K Kroemer Matthias Nauck Sylvia Stracke Uwe Völker Henry Völzke Peter Kovacs Michael Stumvoll Reedik Mägi Albert Hofman Andre G Uitterlinden Fernando Rivadeneira Yurii S Aulchenko Ozren Polasek Nick Hastie Veronique Vitart Catherine Helmer Jie Jin Wang Bénédicte Stengel Daniela Ruggiero Sven Bergmann Mika Kähönen Jorma Viikari Tiit Nikopensius Michael Province Helen Colhoun Alex Doney Antonietta Robino Bernhard K Krämer Laura Portas Ian Ford Brendan M Buckley Martin Adam Gian-Andri Thun Bernhard Paulweber Margot Haun Cinzia Sala Paul Mitchell Marina Ciullo Peter Vollenweider Olli Raitakari Andres Metspalu Colin Palmer Paolo Gasparini Mario Pirastu J Wouter Jukema Nicole M Probst-Hensch Florian Kronenberg Daniela Toniolo Vilmundur Gudnason Alan R Shuldiner Josef Coresh Reinhold Schmidt Luigi Ferrucci Cornelia M van Duijn Ingrid Borecki Sharon L R Kardia Yongmei Liu Gary C Curhan Igor Rudan Ulf Gyllensten James F Wilson Andre Franke Peter P Pramstaller Rainer Rettig Inga Prokopenko Jacqueline Witteman Caroline Hayward Paul M Ridker Murielle Bochud Iris M Heid David S Siscovick Caroline S Fox W Linda Kao Carsten A Böger

J Am Soc Nephrol 2013 Dec 12;24(12):2105-17. Epub 2013 Sep 12.

Division of Nephrology, University of Maryland School of Medicine, Baltimore, Maryland;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839542PMC
December 2013

Biobanking across the phenome - at the center of chronic disease research.

BMC Public Health 2013 Nov 25;13:1094. Epub 2013 Nov 25.

Swiss Tropical and Public Health Institute, Basel, Switzerland.

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http://dx.doi.org/10.1186/1471-2458-13-1094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222669PMC
November 2013

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.

PLoS Genet 2012 20;8(12):e1003098. Epub 2012 Dec 20.

Behavioral Health Epidemiology Program, Research Triangle Institute International, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1371/journal.pgen.1003098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527213PMC
May 2013

The association of a variant in the cell cycle control gene CCND1 and obesity on the development of asthma in the Swiss SAPALDIA study.

J Asthma 2013 Mar 13;50(2):147-54. Epub 2013 Jan 13.

Swiss Tropical and Public Health Institute, Basel, Switzerland.

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http://dx.doi.org/10.3109/02770903.2012.757776DOI Listing
March 2013

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.

Authors:
Anna Köttgen Eva Albrecht Alexander Teumer Veronique Vitart Jan Krumsiek Claudia Hundertmark Giorgio Pistis Daniela Ruggiero Conall M O'Seaghdha Toomas Haller Qiong Yang Toshiko Tanaka Andrew D Johnson Zoltán Kutalik Albert V Smith Julia Shi Maksim Struchalin Rita P S Middelberg Morris J Brown Angelo L Gaffo Nicola Pirastu Guo Li Caroline Hayward Tatijana Zemunik Jennifer Huffman Loic Yengo Jing Hua Zhao Ayse Demirkan Mary F Feitosa Xuan Liu Giovanni Malerba Lorna M Lopez Pim van der Harst Xinzhong Li Marcus E Kleber Andrew A Hicks Ilja M Nolte Asa Johansson Federico Murgia Sarah H Wild Stephan J L Bakker John F Peden Abbas Dehghan Maristella Steri Albert Tenesa Vasiliki Lagou Perttu Salo Massimo Mangino Lynda M Rose Terho Lehtimäki Owen M Woodward Yukinori Okada Adrienne Tin Christian Müller Christopher Oldmeadow Margus Putku Darina Czamara Peter Kraft Laura Frogheri Gian Andri Thun Anne Grotevendt Gauti Kjartan Gislason Tamara B Harris Lenore J Launer Patrick McArdle Alan R Shuldiner Eric Boerwinkle Josef Coresh Helena Schmidt Michael Schallert Nicholas G Martin Grant W Montgomery Michiaki Kubo Yusuke Nakamura Toshihiro Tanaka Patricia B Munroe Nilesh J Samani David R Jacobs Kiang Liu Pio D'Adamo Sheila Ulivi Jerome I Rotter Bruce M Psaty Peter Vollenweider Gerard Waeber Susan Campbell Olivier Devuyst Pau Navarro Ivana Kolcic Nicholas Hastie Beverley Balkau Philippe Froguel Tõnu Esko Andres Salumets Kay Tee Khaw Claudia Langenberg Nicholas J Wareham Aaron Isaacs Aldi Kraja Qunyuan Zhang Philipp S Wild Rodney J Scott Elizabeth G Holliday Elin Org Margus Viigimaa Stefania Bandinelli Jeffrey E Metter Antonio Lupo Elisabetta Trabetti Rossella Sorice Angela Döring Eva Lattka Konstantin Strauch Fabian Theis Melanie Waldenberger H-Erich Wichmann Gail Davies Alan J Gow Marcel Bruinenberg Ronald P Stolk Jaspal S Kooner Weihua Zhang Bernhard R Winkelmann Bernhard O Boehm Susanne Lucae Brenda W Penninx Johannes H Smit Gary Curhan Poorva Mudgal Robert M Plenge Laura Portas Ivana Persico Mirna Kirin James F Wilson Irene Mateo Leach Wiek H van Gilst Anuj Goel Halit Ongen Albert Hofman Fernando Rivadeneira Andre G Uitterlinden Medea Imboden Arnold von Eckardstein Francesco Cucca Ramaiah Nagaraja Maria Grazia Piras Matthias Nauck Claudia Schurmann Kathrin Budde Florian Ernst Susan M Farrington Evropi Theodoratou Inga Prokopenko Michael Stumvoll Antti Jula Markus Perola Veikko Salomaa So-Youn Shin Tim D Spector Cinzia Sala Paul M Ridker Mika Kähönen Jorma Viikari Christian Hengstenberg Christopher P Nelson James F Meschia Michael A Nalls Pankaj Sharma Andrew B Singleton Naoyuki Kamatani Tanja Zeller Michel Burnier John Attia Maris Laan Norman Klopp Hans L Hillege Stefan Kloiber Hyon Choi Mario Pirastu Silvia Tore Nicole M Probst-Hensch Henry Völzke Vilmundur Gudnason Afshin Parsa Reinhold Schmidt John B Whitfield Myriam Fornage Paolo Gasparini David S Siscovick Ozren Polašek Harry Campbell Igor Rudan Nabila Bouatia-Naji Andres Metspalu Ruth J F Loos Cornelia M van Duijn Ingrid B Borecki Luigi Ferrucci Giovanni Gambaro Ian J Deary Bruce H R Wolffenbuttel John C Chambers Winfried März Peter P Pramstaller Harold Snieder Ulf Gyllensten Alan F Wright Gerjan Navis Hugh Watkins Jacqueline C M Witteman Serena Sanna Sabine Schipf Malcolm G Dunlop Anke Tönjes Samuli Ripatti Nicole Soranzo Daniela Toniolo Daniel I Chasman Olli Raitakari W H Linda Kao Marina Ciullo Caroline S Fox Mark Caulfield Murielle Bochud Christian Gieger

Nat Genet 2013 Feb 23;45(2):145-54. Epub 2012 Dec 23.

Renal Division, Freiburg University Hospital, Freiburg, Germany.

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http://dx.doi.org/10.1038/ng.2500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663712PMC
February 2013

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function.

Authors:
Daniel I Chasman Christian Fuchsberger Cristian Pattaro Alexander Teumer Carsten A Böger Karlhans Endlich Matthias Olden Ming-Huei Chen Adrienne Tin Daniel Taliun Man Li Xiaoyi Gao Mathias Gorski Qiong Yang Claudia Hundertmark Meredith C Foster Conall M O'Seaghdha Nicole Glazer Aaron Isaacs Ching-Ti Liu Albert V Smith Jeffrey R O'Connell Maksim Struchalin Toshiko Tanaka Guo Li Andrew D Johnson Hinco J Gierman Mary F Feitosa Shih-Jen Hwang Elizabeth J Atkinson Kurt Lohman Marilyn C Cornelis Asa Johansson Anke Tönjes Abbas Dehghan Jean-Charles Lambert Elizabeth G Holliday Rossella Sorice Zoltan Kutalik Terho Lehtimäki Tõnu Esko Harshal Deshmukh Sheila Ulivi Audrey Y Chu Federico Murgia Stella Trompet Medea Imboden Stefan Coassin Giorgio Pistis Tamara B Harris Lenore J Launer Thor Aspelund Gudny Eiriksdottir Braxton D Mitchell Eric Boerwinkle Helena Schmidt Margherita Cavalieri Madhumathi Rao Frank Hu Ayse Demirkan Ben A Oostra Mariza de Andrade Stephen T Turner Jingzhong Ding Jeanette S Andrews Barry I Freedman Franco Giulianini Wolfgang Koenig Thomas Illig Christa Meisinger Christian Gieger Lina Zgaga Tatijana Zemunik Mladen Boban Cosetta Minelli Heather E Wheeler Wilmar Igl Ghazal Zaboli Sarah H Wild Alan F Wright Harry Campbell David Ellinghaus Ute Nöthlings Gunnar Jacobs Reiner Biffar Florian Ernst Georg Homuth Heyo K Kroemer Matthias Nauck Sylvia Stracke Uwe Völker Henry Völzke Peter Kovacs Michael Stumvoll Reedik Mägi Albert Hofman Andre G Uitterlinden Fernando Rivadeneira Yurii S Aulchenko Ozren Polasek Nick Hastie Veronique Vitart Catherine Helmer Jie Jin Wang Bénédicte Stengel Daniela Ruggiero Sven Bergmann Mika Kähönen Jorma Viikari Tiit Nikopensius Michael Province Shamika Ketkar Helen Colhoun Alex Doney Antonietta Robino Bernhard K Krämer Laura Portas Ian Ford Brendan M Buckley Martin Adam Gian-Andri Thun Bernhard Paulweber Margot Haun Cinzia Sala Paul Mitchell Marina Ciullo Stuart K Kim Peter Vollenweider Olli Raitakari Andres Metspalu Colin Palmer Paolo Gasparini Mario Pirastu J Wouter Jukema Nicole M Probst-Hensch Florian Kronenberg Daniela Toniolo Vilmundur Gudnason Alan R Shuldiner Josef Coresh Reinhold Schmidt Luigi Ferrucci David S Siscovick Cornelia M van Duijn Ingrid B Borecki Sharon L R Kardia Yongmei Liu Gary C Curhan Igor Rudan Ulf Gyllensten James F Wilson Andre Franke Peter P Pramstaller Rainer Rettig Inga Prokopenko Jacqueline Witteman Caroline Hayward Paul M Ridker Afshin Parsa Murielle Bochud Iris M Heid W H Linda Kao Caroline S Fox Anna Köttgen

Hum Mol Genet 2012 Dec 8;21(24):5329-43. Epub 2012 Sep 8.

Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA.

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http://dx.doi.org/10.1093/hmg/dds369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607468PMC
December 2012

Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.

Am J Respir Crit Care Med 2012 Oct 26;186(7):622-32. Epub 2012 Jul 26.

Division of Aging, Brigham and Women's Hospital and Harvard Medical School, 1620 Tremont Street, Boston, MA 02120, USA.

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http://dx.doi.org/10.1164/rccm.201202-0366OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480517PMC
October 2012

Genome-wide association and functional follow-up reveals new loci for kidney function.

Authors:
Cristian Pattaro Anna Köttgen Alexander Teumer Maija Garnaas Carsten A Böger Christian Fuchsberger Matthias Olden Ming-Huei Chen Adrienne Tin Daniel Taliun Man Li Xiaoyi Gao Mathias Gorski Qiong Yang Claudia Hundertmark Meredith C Foster Conall M O'Seaghdha Nicole Glazer Aaron Isaacs Ching-Ti Liu Albert V Smith Jeffrey R O'Connell Maksim Struchalin Toshiko Tanaka Guo Li Andrew D Johnson Hinco J Gierman Mary Feitosa Shih-Jen Hwang Elizabeth J Atkinson Kurt Lohman Marilyn C Cornelis Åsa Johansson Anke Tönjes Abbas Dehghan Vincent Chouraki Elizabeth G Holliday Rossella Sorice Zoltan Kutalik Terho Lehtimäki Tõnu Esko Harshal Deshmukh Sheila Ulivi Audrey Y Chu Federico Murgia Stella Trompet Medea Imboden Barbara Kollerits Giorgio Pistis Tamara B Harris Lenore J Launer Thor Aspelund Gudny Eiriksdottir Braxton D Mitchell Eric Boerwinkle Helena Schmidt Margherita Cavalieri Madhumathi Rao Frank B Hu Ayse Demirkan Ben A Oostra Mariza de Andrade Stephen T Turner Jingzhong Ding Jeanette S Andrews Barry I Freedman Wolfgang Koenig Thomas Illig Angela Döring H-Erich Wichmann Ivana Kolcic Tatijana Zemunik Mladen Boban Cosetta Minelli Heather E Wheeler Wilmar Igl Ghazal Zaboli Sarah H Wild Alan F Wright Harry Campbell David Ellinghaus Ute Nöthlings Gunnar Jacobs Reiner Biffar Karlhans Endlich Florian Ernst Georg Homuth Heyo K Kroemer Matthias Nauck Sylvia Stracke Uwe Völker Henry Völzke Peter Kovacs Michael Stumvoll Reedik Mägi Albert Hofman Andre G Uitterlinden Fernando Rivadeneira Yurii S Aulchenko Ozren Polasek Nick Hastie Veronique Vitart Catherine Helmer Jie Jin Wang Daniela Ruggiero Sven Bergmann Mika Kähönen Jorma Viikari Tiit Nikopensius Michael Province Shamika Ketkar Helen Colhoun Alex Doney Antonietta Robino Franco Giulianini Bernhard K Krämer Laura Portas Ian Ford Brendan M Buckley Martin Adam Gian-Andri Thun Bernhard Paulweber Margot Haun Cinzia Sala Marie Metzger Paul Mitchell Marina Ciullo Stuart K Kim Peter Vollenweider Olli Raitakari Andres Metspalu Colin Palmer Paolo Gasparini Mario Pirastu J Wouter Jukema Nicole M Probst-Hensch Florian Kronenberg Daniela Toniolo Vilmundur Gudnason Alan R Shuldiner Josef Coresh Reinhold Schmidt Luigi Ferrucci David S Siscovick Cornelia M van Duijn Ingrid Borecki Sharon L R Kardia Yongmei Liu Gary C Curhan Igor Rudan Ulf Gyllensten James F Wilson Andre Franke Peter P Pramstaller Rainer Rettig Inga Prokopenko Jacqueline C M Witteman Caroline Hayward Paul Ridker Afshin Parsa Murielle Bochud Iris M Heid Wolfram Goessling Daniel I Chasman W H Linda Kao Caroline S Fox

PLoS Genet 2012 29;8(3):e1002584. Epub 2012 Mar 29.

Institute of Genetic Medicine, European Academy of Bozen/Bolzano (EURAC) and Affiliated Institute of the University of Lübeck, Bolzano, Italy.

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http://dx.doi.org/10.1371/journal.pgen.1002584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315455PMC
September 2012

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.

Authors:
Lavinia Paternoster Marie Standl Chih-Mei Chen Adaikalavan Ramasamy Klaus Bønnelykke Liesbeth Duijts Manuel A Ferreira Alexessander Couto Alves Jacob P Thyssen Eva Albrecht Hansjörg Baurecht Bjarke Feenstra Patrick M A Sleiman Pirro Hysi Nicole M Warrington Ivan Curjuric Ronny Myhre John A Curtin Maria M Groen-Blokhuis Marjan Kerkhof Annika Sääf Andre Franke David Ellinghaus Regina Fölster-Holst Emmanouil Dermitzakis Stephen B Montgomery Holger Prokisch Katharina Heim Anna-Liisa Hartikainen Anneli Pouta Juha Pekkanen Alexandra I F Blakemore Jessica L Buxton Marika Kaakinen David L Duffy Pamela A Madden Andrew C Heath Grant W Montgomery Philip J Thompson Melanie C Matheson Peter Le Souëf Beate St Pourcain George Davey Smith John Henderson John P Kemp Nicholas J Timpson Panos Deloukas Susan M Ring H-Erich Wichmann Martina Müller-Nurasyid Natalija Novak Norman Klopp Elke Rodríguez Wendy McArdle Allan Linneberg Torkil Menné Ellen A Nohr Albert Hofman André G Uitterlinden Cornélia M van Duijn Fernando Rivadeneira Johan C de Jongste Ralf J P van der Valk Matthias Wjst Rain Jogi Frank Geller Heather A Boyd Jeffrey C Murray Cecilia Kim Frank Mentch Michael March Massimo Mangino Tim D Spector Veronique Bataille Craig E Pennell Patrick G Holt Peter Sly Carla M T Tiesler Elisabeth Thiering Thomas Illig Medea Imboden Wenche Nystad Angela Simpson Jouke-Jan Hottenga Dirkje Postma Gerard H Koppelman Henriette A Smit Cilla Söderhäll Bo Chawes Eskil Kreiner-Møller Hans Bisgaard Erik Melén Dorret I Boomsma Adnan Custovic Bo Jacobsson Nicole M Probst-Hensch Lyle J Palmer Daniel Glass Hakon Hakonarson Mads Melbye Deborah L Jarvis Vincent W V Jaddoe Christian Gieger David P Strachan Nicholas G Martin Marjo-Riitta Jarvelin Joachim Heinrich David M Evans Stephan Weidinger

Nat Genet 2011 Dec 25;44(2):187-92. Epub 2011 Dec 25.

Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, UK.

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http://www.nature.com/doifinder/10.1038/ng.1017
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http://dx.doi.org/10.1038/ng.1017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272375PMC
December 2011

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

Authors:
María Soler Artigas Daan W Loth Louise V Wain Sina A Gharib Ma'en Obeidat Wenbo Tang Guangju Zhai Jing Hua Zhao Albert Vernon Smith Jennifer E Huffman Eva Albrecht Catherine M Jackson David M Evans Gemma Cadby Myriam Fornage Ani Manichaikul Lorna M Lopez Toby Johnson Melinda C Aldrich Thor Aspelund Inês Barroso Harry Campbell Patricia A Cassano David J Couper Gudny Eiriksdottir Nora Franceschini Melissa Garcia Christian Gieger Gauti Kjartan Gislason Ivica Grkovic Christopher J Hammond Dana B Hancock Tamara B Harris Adaikalavan Ramasamy Susan R Heckbert Markku Heliövaara Georg Homuth Pirro G Hysi Alan L James Stipan Jankovic Bonnie R Joubert Stefan Karrasch Norman Klopp Beate Koch Stephen B Kritchevsky Lenore J Launer Yongmei Liu Laura R Loehr Kurt Lohman Ruth J F Loos Thomas Lumley Khalid A Al Balushi Wei Q Ang R Graham Barr John Beilby John D Blakey Mladen Boban Vesna Boraska Jonas Brisman John R Britton Guy G Brusselle Cyrus Cooper Ivan Curjuric Santosh Dahgam Ian J Deary Shah Ebrahim Mark Eijgelsheim Clyde Francks Darya Gaysina Raquel Granell Xiangjun Gu John L Hankinson Rebecca Hardy Sarah E Harris John Henderson Amanda Henry Aroon D Hingorani Albert Hofman Patrick G Holt Jennie Hui Michael L Hunter Medea Imboden Karen A Jameson Shona M Kerr Ivana Kolcic Florian Kronenberg Jason Z Liu Jonathan Marchini Tricia McKeever Andrew D Morris Anna-Carin Olin David J Porteous Dirkje S Postma Stephen S Rich Susan M Ring Fernando Rivadeneira Thierry Rochat Avan Aihie Sayer Ian Sayers Peter D Sly George Davey Smith Akshay Sood John M Starr André G Uitterlinden Judith M Vonk S Goya Wannamethee Peter H Whincup Cisca Wijmenga O Dale Williams Andrew Wong Massimo Mangino Kristin D Marciante Wendy L McArdle Bernd Meibohm Alanna C Morrison Kari E North Ernst Omenaas Lyle J Palmer Kirsi H Pietiläinen Isabelle Pin Ozren Pola Sbreve Ek Anneli Pouta Bruce M Psaty Anna-Liisa Hartikainen Taina Rantanen Samuli Ripatti Jerome I Rotter Igor Rudan Alicja R Rudnicka Holger Schulz So-Youn Shin Tim D Spector Ida Surakka Veronique Vitart Henry Völzke Nicholas J Wareham Nicole M Warrington H-Erich Wichmann Sarah H Wild Jemma B Wilk Matthias Wjst Alan F Wright Lina Zgaga Tatijana Zemunik Craig E Pennell Fredrik Nyberg Diana Kuh John W Holloway H Marike Boezen Debbie A Lawlor Richard W Morris Nicole Probst-Hensch Jaakko Kaprio James F Wilson Caroline Hayward Mika Kähönen Joachim Heinrich Arthur W Musk Deborah L Jarvis Sven Gläser Marjo-Riitta Järvelin Bruno H Ch Stricker Paul Elliott George T O'Connor David P Strachan Stephanie J London Ian P Hall Vilmundur Gudnason Martin D Tobin

Nat Genet 2011 Sep 25;43(11):1082-90. Epub 2011 Sep 25.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/ng.941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267376PMC
September 2011

Association of STR polymorphisms in CMA1 and IL-4 with asthma and atopy: the SAPALDIA cohort.

Hum Immunol 2010 Nov 22;71(11):1154-60. Epub 2010 Aug 22.

Division of Clinical Chemistry and Biochemistry, University Children's Hospital Zurich and Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.humimm.2010.08.008DOI Listing
November 2010

New loci associated with kidney function and chronic kidney disease.

Authors:
Anna Köttgen Cristian Pattaro Carsten A Böger Christian Fuchsberger Matthias Olden Nicole L Glazer Afshin Parsa Xiaoyi Gao Qiong Yang Albert V Smith Jeffrey R O'Connell Man Li Helena Schmidt Toshiko Tanaka Aaron Isaacs Shamika Ketkar Shih-Jen Hwang Andrew D Johnson Abbas Dehghan Alexander Teumer Guillaume Paré Elizabeth J Atkinson Tanja Zeller Kurt Lohman Marilyn C Cornelis Nicole M Probst-Hensch Florian Kronenberg Anke Tönjes Caroline Hayward Thor Aspelund Gudny Eiriksdottir Lenore J Launer Tamara B Harris Evadnie Rampersaud Braxton D Mitchell Dan E Arking Eric Boerwinkle Maksim Struchalin Margherita Cavalieri Andrew Singleton Francesco Giallauria Jeffrey Metter Ian H de Boer Talin Haritunians Thomas Lumley David Siscovick Bruce M Psaty M Carola Zillikens Ben A Oostra Mary Feitosa Michael Province Mariza de Andrade Stephen T Turner Arne Schillert Andreas Ziegler Philipp S Wild Renate B Schnabel Sandra Wilde Thomas F Munzel Tennille S Leak Thomas Illig Norman Klopp Christa Meisinger H-Erich Wichmann Wolfgang Koenig Lina Zgaga Tatijana Zemunik Ivana Kolcic Cosetta Minelli Frank B Hu Asa Johansson Wilmar Igl Ghazal Zaboli Sarah H Wild Alan F Wright Harry Campbell David Ellinghaus Stefan Schreiber Yurii S Aulchenko Janine F Felix Fernando Rivadeneira Andre G Uitterlinden Albert Hofman Medea Imboden Dorothea Nitsch Anita Brandstätter Barbara Kollerits Lyudmyla Kedenko Reedik Mägi Michael Stumvoll Peter Kovacs Mladen Boban Susan Campbell Karlhans Endlich Henry Völzke Heyo K Kroemer Matthias Nauck Uwe Völker Ozren Polasek Veronique Vitart Sunita Badola Alexander N Parker Paul M Ridker Sharon L R Kardia Stefan Blankenberg Yongmei Liu Gary C Curhan Andre Franke Thierry Rochat Bernhard Paulweber Inga Prokopenko Wei Wang Vilmundur Gudnason Alan R Shuldiner Josef Coresh Reinhold Schmidt Luigi Ferrucci Michael G Shlipak Cornelia M van Duijn Ingrid Borecki Bernhard K Krämer Igor Rudan Ulf Gyllensten James F Wilson Jacqueline C Witteman Peter P Pramstaller Rainer Rettig Nick Hastie Daniel I Chasman W H Kao Iris M Heid Caroline S Fox

Nat Genet 2010 May 11;42(5):376-84. Epub 2010 Apr 11.

Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1038/ng.568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997674PMC
May 2010

Genome-wide association study identifies five loci associated with lung function.

Nat Genet 2010 Jan 13;42(1):36-44. Epub 2009 Dec 13.

Departments of Health Sciences and Genetics, Adrian Building, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/ng.501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862965PMC
January 2010

Decreased PM10 exposure attenuates age-related lung function decline: genetic variants in p53, p21, and CCND1 modify this effect.

Environ Health Perspect 2009 Sep 26;117(9):1420-7. Epub 2009 May 26.

Department of Chronic Disease Epidemiology, Institute of Social and Preventive Medicine, University of Zurich, Sumatrastrasse 30, Zurich, Switzerland.

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http://dx.doi.org/10.1289/ehp.0800430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737020PMC
September 2009

SERPINA1 gene variants in individuals from the general population with reduced alpha1-antitrypsin concentrations.

Clin Chem 2008 Aug 29;54(8):1331-8. Epub 2008 May 29.

Center for Diagnosis of Severe Alpha1-antitrypsin Deficiency, Laboratory of Biochemistry and Genetics, Institute for Respiratory Disease and Unit of Statistics and Biometry, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Italy.

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http://dx.doi.org/10.1373/clinchem.2007.102798DOI Listing
August 2008

Circulating alpha1-antitrypsin in the general population: determinants and association with lung function.

Respir Res 2008 Apr 25;9:35. Epub 2008 Apr 25.

Molecular Epidemiology/Cancer Registry, Institutes of Social and Preventive Medicine & Clinical Pathology, University of Zurich, Zürich, Switzerland.

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http://dx.doi.org/10.1186/1465-9921-9-35DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413219PMC
April 2008

Glutathione S-transferase genotypes modify lung function decline in the general population: SAPALDIA cohort study.

Respir Res 2007 Jan 11;8. Epub 2007 Jan 11.

Institutes of Social and Preventive Medicine & Surgical Pathology, Molecular Epidemiology/Cancer Registry, University of Zurich & University Hospital Zurich, Switzerland.

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http://dx.doi.org/10.1186/1465-9921-8-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781067PMC
January 2007

Female predominance and transmission distortion in the long-QT syndrome.

N Engl J Med 2006 Dec;355(26):2744-51

INSERM, Institut de Myologie, Université Pierre et Marie Curie, Institut Fédératif de Recherche 14 and Groupe Hospitalier Pitié-Salpêtrière, Paris, France.

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http://dx.doi.org/10.1056/NEJMoa042786DOI Listing
December 2006