Publications by authors named "Maziar Divangahi"

74Publications

Lessons from BCG for SARS-CoV-2 vaccine candidates.

J Infect Dis 2020 Nov 30. Epub 2020 Nov 30.

Department of Medicine, McGill University.

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http://dx.doi.org/10.1093/infdis/jiaa637DOI Listing
November 2020

Can BCG be useful to mitigate the COVID-19 pandemic? A Canadian perspective.

Can J Public Health 2020 Nov 19. Epub 2020 Nov 19.

Meakins-Christie Laboratories, Department of Medicine, McGill University Health Centre, Montreal, QC, Canada.

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http://dx.doi.org/10.17269/s41997-020-00439-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676406PMC
November 2020

M. tuberculosis Reprograms Hematopoietic Stem Cells to Limit Myelopoiesis and Impair Trained Immunity.

Cell 2020 Oct;183(3):752-770.e22

Meakins-Christie Laboratories, Department of Medicine, Department of Microbiology and Immunology, Department of Pathology, McGill University, Montreal, QC, Canada; McGill International TB Centre, McGill University Health Centre, Montreal, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.09.062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599081PMC
October 2020

Targeting immunometabolism in host defence against Mycobacterium tuberculosis.

Immunology 2020 Oct 6. Epub 2020 Oct 6.

Meakins-Christie Laboratories, Department of Medicine, Department of Pathology, Department of Microbiology & Immunology, McGill University Health Centre, McGill International TB Centre, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1111/imm.13276DOI Listing
October 2020

β-Glucan Induces Protective Trained Immunity against Mycobacterium tuberculosis Infection: A Key Role for IL-1.

Cell Rep 2020 05;31(7):107634

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242907PMC
May 2020

Cyclophilin D Regulates Antiviral CD8 T Cell Survival in a Cell-Extrinsic Manner.

Immunohorizons 2020 04 24;4(4):217-230. Epub 2020 Apr 24.

Department of Microbiology and Immunology, McGill University, Montreal, Quebec H3G 1Y6, Canada;

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http://dx.doi.org/10.4049/immunohorizons.2000016DOI Listing
April 2020

Publisher Correction: Regulation of protein kinase Cδ Nuclear Import and Apoptosis by Mechanistic Target of Rapamycin Complex-1.

Sci Rep 2020 Feb 19;10(1):3337. Epub 2020 Feb 19.

Meakins-Christie Laboratories and Translational Research in Respiratory Diseases Program, Research Institute of the McGill University Health Centre, Faculty of Medicine, Departments of Medicine and Critical Care, 1001 Décarie Boulevard, EM3.2219, Montreal, Québec, H4A 3J1, Canada.

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http://dx.doi.org/10.1038/s41598-020-58962-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031502PMC
February 2020

Editorial: Evolving Mechanisms of Disease Tolerance.

Front Immunol 2019 20;10:2974. Epub 2019 Dec 20.

Meakins-Christie Laboratories, Department of Medicine, McGill University Health Centre, Montreal, QC, Canada.

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http://dx.doi.org/10.3389/fimmu.2019.02974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934019PMC
November 2020

NK cell recruitment limits tissue damage during an enteric helminth infection.

Mucosal Immunol 2020 03 27;13(2):357-370. Epub 2019 Nov 27.

Meakins-Christie Laboratories, Department of Medicine, McGill University Health Centre, Montreal, QC, H4A 3J1, Canada.

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http://dx.doi.org/10.1038/s41385-019-0231-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039810PMC
March 2020

Regulation of protein kinase Cδ Nuclear Import and Apoptosis by Mechanistic Target of Rapamycin Complex-1.

Sci Rep 2019 11 26;9(1):17620. Epub 2019 Nov 26.

Meakins-Christie Laboratories and Translational Research in Respiratory Diseases Program, Research Institute of the McGill University Health Centre, Faculty of Medicine, Departments of Medicine and Critical Care, 1001 Décarie Boulevard, EM3.2219, Montreal, Québec, H4A 3J1, Canada.

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http://dx.doi.org/10.1038/s41598-019-53909-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879585PMC
November 2019

[Loss of human ICOSLG results in combined immunodeficiency].

Med Sci (Paris) 2019 Aug-Sep;35(8-9):625-628. Epub 2019 Sep 18.

Le Programme en maladies infectieuses et immunité en santé mondiale, Centre universitaire de santé McGill, Institut de recherche, 1001 Decarie, H4A3J1 Montréal, Québec, Canada. - Laboratoire d'oncologie moléculaire, Institut de recherches cliniques de Montréal, Montréal, Québec, Canada. - Département de médecine, Université McGill, Montréal, Québec, Canada. - Département de médecine, Université de Montréal, Montréal, Québec, Canada.

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http://dx.doi.org/10.1051/medsci/2019126DOI Listing
April 2020

Targeting innate immunity for tuberculosis vaccination.

J Clin Invest 2019 09;129(9):3482-3491

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, Netherlands.

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http://dx.doi.org/10.1172/JCI128877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715374PMC
September 2019

Tolerogenic signaling of alveolar macrophages induces lung adaptation to oxidative injury.

J Allergy Clin Immunol 2019 10 26;144(4):945-961.e9. Epub 2019 Jul 26.

Meakins Christie Laboratories, Research Institute of the McGill University Health Centre, and the Department of Medicine, McGill University, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.07.015DOI Listing
October 2019

Necroptotic cell binding of β -glycoprotein I provides a potential autoantigenic stimulus in systemic lupus erythematosus.

Immunol Cell Biol 2019 10 12;97(9):799-814. Epub 2019 Jun 12.

Division of Rheumatology, Department of Medicine, McGill University, Infectious Diseases and Immunity in Global Health Programme, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1111/imcb.12279DOI Listing
October 2019

Leukotriene B-type I interferon axis regulates macrophage-mediated disease tolerance to influenza infection.

Nat Microbiol 2019 08 20;4(8):1389-1400. Epub 2019 May 20.

Department of Medicine, Meakins-Christie Laboratories, McGill International TB Centre, McGill University Health Centre, McGill University, Montreal, Quebec, Canada.

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http://www.nature.com/articles/s41564-019-0444-3
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http://dx.doi.org/10.1038/s41564-019-0444-3DOI Listing
August 2019

Intestinal dysbiosis compromises alveolar macrophage immunity to Mycobacterium tuberculosis.

Mucosal Immunol 2019 05 19;12(3):772-783. Epub 2019 Feb 19.

Meakins-Christie Laboratories, Department of Medicine, Department of Pathology, McGill University Health Centre, Montreal, QC, H4A 3J1, Canada.

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http://dx.doi.org/10.1038/s41385-019-0147-3DOI Listing
May 2019

Beyond Killing : Disease Tolerance.

Front Immunol 2018 19;9:2976. Epub 2018 Dec 19.

Meakins-Christie Laboratories, Departments of Medicine, Microbiology and Immunology, Pathology McGill University, McGill International TB Centre, McGill University Health Centre, Montreal, QC, Canada.

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02976
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http://dx.doi.org/10.3389/fimmu.2018.02976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305711PMC
October 2019

Are tolerance and training required to end TB?

Authors:
Maziar Divangahi

Nat Rev Immunol 2018 11;18(11):661-663

Departments of Medicine, Microbiology and Immunology, and Pathology, Meakins-Christie Laboratories, McGill International TB Centre and McGill University Health Centre, McGill University, Montreal, Québec, Canada.

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http://dx.doi.org/10.1038/s41577-018-0070-yDOI Listing
November 2018

Mitochondrial cyclophilin D regulates T cell metabolic responses and disease tolerance to tuberculosis.

Sci Immunol 2018 05;3(23)

Department of Medicine, Department of Microbiology and Immunology, Department of Pathology, McGill University Health Centre, McGill International TB Centre, Meakins-Christie Laboratories, McGill University, 1001 Decarie Boulevard, Montreal, Quebec H4A 3J1, Canada.

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http://dx.doi.org/10.1126/sciimmunol.aar4135DOI Listing
May 2018

Dissecting host cell death programs in the pathogenesis of influenza.

Microbes Infect 2018 Oct - Nov;20(9-10):560-569. Epub 2018 Apr 18.

Department of Medicine, Department of Microbiology & Immunology, Department of Pathology, McGill University Health Centre, McGill International TB Centre, Meakins-Christie Laboratories, McGill University, 1001 Decarie Boulevard, Montreal, Quebec H4A 3J1, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S12864579183009
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http://dx.doi.org/10.1016/j.micinf.2018.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110448PMC
September 2019

Mycobacterium tuberculosis and HIV Coinfection Brings Fire and Fury to Macrophages.

J Infect Dis 2018 05;217(12):1851-1853

Meakins-Christie Laboratories, McGill University Health Centre, Montreal, Canada.

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http://dx.doi.org/10.1093/infdis/jix626DOI Listing
May 2018

Aged polymorphonuclear leukocytes cause fibrotic interstitial lung disease in the absence of regulation by B cells.

Nat Immunol 2018 02 15;19(2):192-201. Epub 2018 Jan 15.

Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.1038/s41590-017-0030-xDOI Listing
February 2018

BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis.

Cell 2018 01;172(1-2):176-190.e19

Meakins-Christie Laboratories, Department of Medicine, Department of Microbiology and Immunology, Department of Pathology, McGill International TB Centre, McGill University Health Centre, Montreal, QC H4A 3J1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.12.031DOI Listing
January 2018

Cracking the Vaccine Code in Tuberculosis.

Am J Respir Crit Care Med 2018 02;197(4):427-432

1 Department of Medicine.

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http://dx.doi.org/10.1164/rccm.201707-1489PPDOI Listing
February 2018

RIPK3 interacts with MAVS to regulate type I IFN-mediated immunity to Influenza A virus infection.

PLoS Pathog 2017 Apr 14;13(4):e1006326. Epub 2017 Apr 14.

Department of Medicine, Department of Pathology, Department of Microbiology & Immunology, McGill University Health Centre, McGill International TB Centre, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1371/journal.ppat.1006326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406035PMC
April 2017

Unravelling the networks dictating host resistance versus tolerance during pulmonary infections.

Cell Tissue Res 2017 03 6;367(3):525-536. Epub 2017 Feb 6.

Department of Medicine, Department of Microbiology & Immunology, and Department of Pathology, McGill University Health Centre, McGill International TB Centre, Meakins-Christie Laboratories, McGill University, 1001 Decarie Boulevard, Montreal, Quebec, H4A 3J1, Canada.

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http://dx.doi.org/10.1007/s00441-017-2572-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088083PMC
March 2017

Semaphorin 4C Protects against Allergic Inflammation: Requirement of Regulatory CD138+ Plasma Cells.

J Immunol 2017 01 23;198(1):71-81. Epub 2016 Nov 23.

The Research Institute of the McGill University Health Centre, Translational Research in Respiratory Diseases Program, Meakins Christie Laboratories, Montreal, Quebec H4A 3J1, Canada;

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http://dx.doi.org/10.4049/jimmunol.1600831DOI Listing
January 2017

Tuberculosis.

Nat Rev Dis Primers 2016 10 27;2:16076. Epub 2016 Oct 27.

Global TB Programme, WHO, Geneva, Switzerland.

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http://dx.doi.org/10.1038/nrdp.2016.76DOI Listing
October 2016

Divergent impact of Toll-like receptor 2 deficiency on repair mechanisms in healthy muscle versus Duchenne muscular dystrophy.

J Pathol 2016 May 16;239(1):10-22. Epub 2016 Mar 16.

Meakins-Christie Laboratories and Program for Translational Research in Respiratory Diseases, McGill University Health Centre Research Institute, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1002/path.4689DOI Listing
May 2016

Efferocytosis: Burying cell corpses to regulate tolerance and immunity.

Authors:
Maziar Divangahi

Oncotarget 2015 Jun;6(17):14721-2

Departments of Medicine, Microbiology & Immunology and Pathology, McGill International TB Centre, McGill University Health Centre, Centre for Translational Biology, Meakins-Christie Laboratories, Montreal, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558104PMC
http://dx.doi.org/10.18632/oncotarget.4402DOI Listing
June 2015

Evolution of the Immune Response to Chronic Airway Colonization with Aspergillus fumigatus Hyphae.

Infect Immun 2015 Sep 29;83(9):3590-600. Epub 2015 Jun 29.

Department of Microbiology and Immunology, McGill University, Montréal, Québec, Canada Department of Medicine, McGill University, Montréal, Québec, Canada

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http://iai.asm.org/content/83/9/3590.full.pdf
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http://iai.asm.org/lookup/doi/10.1128/IAI.00359-15
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http://dx.doi.org/10.1128/IAI.00359-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534667PMC
September 2015

Alveolar macrophages and type I IFN in airway homeostasis and immunity.

Trends Immunol 2015 May 3;36(5):307-14. Epub 2015 Apr 3.

Department of Medicine, Department of Pathology, McGill International TB Centre, McGill University Health Centre, Meakins-Christie Laboratories, Montreal, QC, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S14714906150005
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http://dx.doi.org/10.1016/j.it.2015.03.005DOI Listing
May 2015

The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo.

Immunity 2015 Jan 2;42(1):41-54. Epub 2015 Jan 2.

Goodman Cancer Research Centre, McGill University, Montreal, QC, H3G 1Y6, Canada; Department of Physiology, McGill University, Montreal, QC, H3G 1Y6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.12.030DOI Listing
January 2015

Freund's adjuvant, NOD2 and mycobacteria.

Curr Opin Microbiol 2015 Feb 5;23:126-32. Epub 2014 Dec 5.

Department of Medicine, McGill University Health Centre, Montreal, Quebec H3G 1A4, Canada; McGill International TB Centre, Montreal H3G 1A4, Canada; Meakins-Christie Laboratories, 3626 St. Urbain Street, Montreal H2X 2P2, Canada.

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http://dx.doi.org/10.1016/j.mib.2014.11.015DOI Listing
February 2015

Targeting eicosanoid pathways in the development of novel anti-influenza drugs.

Expert Rev Anti Infect Ther 2014 Nov 30;12(11):1337-43. Epub 2014 Sep 30.

Department of Medicine, Department of Microbiology and Immunology, Department of Pathology, McGill International TB Centre, McGill University Health Centre, Meakins-Christie Laboratories, 3626 St. Urbain Street, Montreal, Quebec, H2X 2P2, Canada.

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http://dx.doi.org/10.1586/14787210.2014.966082DOI Listing
November 2014

NLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein.

Proc Natl Acad Sci U S A 2014 May 5;111(20):E2110-9. Epub 2014 May 5.

Department of Medicine, Department of Microbiology and Immunology, Department of Pathology, McGill University Health Centre, McGill International TB Centre, Meakins-Christie Laboratories, McGill University, Montreal, QC, Canada H2X 2P2;

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http://dx.doi.org/10.1073/pnas.1322118111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034189PMC
May 2014

Targeted prostaglandin E2 inhibition enhances antiviral immunity through induction of type I interferon and apoptosis in macrophages.

Immunity 2014 Apr 10;40(4):554-68. Epub 2014 Apr 10.

Department of Medicine, Department of Microbiology & Immunology, Department of Pathology, McGill International TB Centre, McGill University Health Centre and Research Institute, Meakins-Christie Laboratories, 3626 St. Urbain Street, Montreal, Quebec H2X 2P2, Canada. Electronic address:

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http://www.cell.com/cms/attachment/2013819407/2035617909/mmc
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http://www.cell.com/cms/attachment/2013819407/2035617910/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S107476131400109
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http://dx.doi.org/10.1016/j.immuni.2014.02.013DOI Listing
April 2014

N-glycolylated peptidoglycan contributes to the immunogenicity but not pathogenicity of Mycobacterium tuberculosis.

J Infect Dis 2014 Apr 21;209(7):1045-54. Epub 2013 Nov 21.

Department of Medicine, Research Institute of the McGill University Health Center, Montreal, Canada.

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http://dx.doi.org/10.1093/infdis/jit622DOI Listing
April 2014

Dying to live: how the death modality of the infected macrophage affects immunity to tuberculosis.

Adv Exp Med Biol 2013 ;783:103-20

Department of Microbiology and Immunology, McGill University Health Centre, Montreal, Canada.

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http://dx.doi.org/10.1007/978-1-4614-6111-1_6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678885PMC
July 2013

Negative regulation of lung inflammation and immunopathology by TNF-α during acute influenza infection.

Am J Pathol 2011 Dec 14;179(6):2963-76. Epub 2011 Oct 14.

Department of Pathology and Molecular Medicine & McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.ajpath.2011.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260802PMC
December 2011

Lipids, apoptosis, and cross-presentation: links in the chain of host defense against Mycobacterium tuberculosis.

Microbes Infect 2011 Aug 31;13(8-9):749-56. Epub 2011 Mar 31.

Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Smith Research Building, 1 Jimmy Fund Way, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.micinf.2011.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130819PMC
August 2011

Evasion of innate immunity by Mycobacterium tuberculosis: is death an exit strategy?

Nat Rev Microbiol 2010 09 2;8(9):668-74. Epub 2010 Aug 2.

Division of Rheumatology, Immunology, and Allergy, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nrmicro2387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221965PMC
September 2010

What's in a name? The (mis)labelling of Crohn's as an autoimmune disease.

Lancet 2010 Jul;376(9736):202-3

Department of Medicine, McGill University Health Centre, Montreal, QC, Canada.

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http://dx.doi.org/10.1016/S0140-6736(10)60282-6DOI Listing
July 2010

Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis.

Nat Immunol 2010 Aug 11;11(8):751-8. Epub 2010 Jul 11.

Division of Rheumatology, Immunology, and Allergy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://www.nature.com/articles/ni.1904
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http://dx.doi.org/10.1038/ni.1904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150169PMC
August 2010

Inspiratory resistive breathing induces acute lung injury.

Am J Respir Crit Care Med 2010 Nov 9;182(9):1129-36. Epub 2010 Jul 9.

Department of Critical Care and Pulmonary Services, Evangelismos Hospital, University of Athens Medical School, Athens, Greece.

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http://www.atsjournals.org/doi/abs/10.1164/rccm.201001-0116O
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http://dx.doi.org/10.1164/rccm.201001-0116OCDOI Listing
November 2010

Lack of CFTR in skeletal muscle predisposes to muscle wasting and diaphragm muscle pump failure in cystic fibrosis mice.

PLoS Genet 2009 Jul 31;5(7):e1000586. Epub 2009 Jul 31.

Meakins-Christie Laboratories and Respiratory Division, McGill University Health Centre and Research Institute, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1371/journal.pgen.1000586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709446PMC
July 2009

Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair.

Nat Immunol 2009 Aug 28;10(8):899-906. Epub 2009 Jun 28.

Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ni.1758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730354PMC
August 2009

Lipid mediators in innate immunity against tuberculosis: opposing roles of PGE2 and LXA4 in the induction of macrophage death.

J Exp Med 2008 Nov 27;205(12):2791-801. Epub 2008 Oct 27.

Department of Medicine, Division of Rheumatology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1084/jem.20080767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585850PMC
November 2008

Airway delivery of soluble mycobacterial antigens restores protective mucosal immunity by single intramuscular plasmid DNA tuberculosis vaccination: role of proinflammatory signals in the lung.

J Immunol 2008 Oct;181(8):5618-26

Centre for Gene Therapeutics, M. G. DeGroote Institute for Infectious Disease Research, and Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.4049/jimmunol.181.8.5618DOI Listing
October 2008

Impact of IL-10 on diaphragmatic cytokine expression and contractility during Pseudomonas Infection.

Am J Respir Cell Mol Biol 2007 Apr 22;36(4):504-12. Epub 2006 Nov 22.

Respiratory Division, Room L411, Royal Victoria Hospital, 687 Pine Ave. West, Montreal, PQ, Canada.

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http://dx.doi.org/10.1165/rcmb.2006-0038OCDOI Listing
April 2007

Intramuscular immunization with a monogenic plasmid DNA tuberculosis vaccine: Enhanced immunogenicity by electroporation and co-expression of GM-CSF transgene.

Vaccine 2007 Jan 10;25(7):1342-52. Epub 2006 Oct 10.

Department of Pathology and Molecular Medicine and Division of Infectious Diseases, Center for Gene Therapeutics, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.vaccine.2006.09.089DOI Listing
January 2007

Toll-like receptors differentially regulate CC and CXC chemokines in skeletal muscle via NF-kappaB and calcineurin.

Infect Immun 2006 Dec 18;74(12):6829-38. Epub 2006 Sep 18.

Respiratory Division, Room L411, Royal Victoria Hospital, 687 Pine Avenue West, Montreal, Quebec H3A 1A1, Canada.

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http://dx.doi.org/10.1128/IAI.00286-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698076PMC
December 2006

Endotoxin triggers nuclear factor-kappaB-dependent up-regulation of multiple proinflammatory genes in the diaphragm.

Am J Respir Crit Care Med 2006 Sep 15;174(6):646-53. Epub 2006 Jun 15.

Meakins-Christie Laboratories, McGill University; and Respiratory Division, McGill University Health Center, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1164/rccm.200509-1511OCDOI Listing
September 2006

Modifications of proteins by 4-hydroxy-2-nonenal in the ventilatory muscles of rats.

Am J Physiol Lung Cell Mol Physiol 2006 May;290(5):L996-1003

Critical Care and Respiratory Divisions, Royal Victoria Hospital, McGill University Health Centre, McGill University, 687 Pine Avenue West, Montreal, Quebec H3A 1A1, Canada.

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http://dx.doi.org/10.1152/ajplung.00337.2005DOI Listing
May 2006

Expression and regulation of CC class chemokines in the dystrophic (mdx) diaphragm.

Am J Respir Cell Mol Biol 2005 Aug 28;33(2):178-85. Epub 2005 Apr 28.

Meakins-Christie Laboratories, and Respiratory Division, McGill University Health Centre, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1165/rcmb.2004-0347OCDOI Listing
August 2005

Therapeutic gene transfer to dystrophic diaphragm by an adenoviral vector deleted of all viral genes.

Am J Physiol Lung Cell Mol Physiol 2004 Sep 21;287(3):L569-76. Epub 2004 May 21.

Respiratory Division, Rm. L411, Royal Victoria Hospital, 687 Pine Ave. W., Montréal, Québec, Canada H3A 1A1.

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http://dx.doi.org/10.1152/ajplung.00117.2004DOI Listing
September 2004

Differential cytokine gene expression in the diaphragm in response to strenuous resistive breathing.

Am J Respir Crit Care Med 2004 Jul 29;170(2):154-61. Epub 2004 Apr 29.

Department of Medicine, McGill University Hospital Center, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1164/rccm.200308-1071OCDOI Listing
July 2004

Preferential diaphragmatic weakness during sustained Pseudomonas aeruginosa lung infection.

Am J Respir Crit Care Med 2004 Mar 11;169(6):679-86. Epub 2003 Dec 11.

Respiratory Division and Meakins-Christie Laboratories, McGill University Health Centre, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1164/rccm.200307-949OCDOI Listing
March 2004

Reduced tissue macrophage population in the lung by anticancer agent cyclophosphamide: restoration by local granulocyte macrophage-colony-stimulating factor gene transfer.

Blood 2002 Feb;99(4):1246-52

Department of Pathology and Molecular Medicine and the Division of Infectious Diseases, Centre for Gene Therapeutics, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1182/blood.v99.4.1246DOI Listing
February 2002