Publications by authors named "Maximus C F Yeung"

3 Publications

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Case report on metastatic pelvic bone tumor treated with frozen autograft by liquid nitrogen.

Int J Surg Case Rep 2021 May 27;82:105910. Epub 2021 Apr 27.

Department of Orthopaedics and Traumatology, Queen Mary Hospital, The University of Hong Kong Pokfulam, Hong Kong.

Introduction And Importance: Frozen autograft recycling has been used for biological reconstruction of bone defects following tumor excision, more commonly in extremities. We report on the histological outcome of a pelvic recycled frozen autograft.

Case Presentation: We investigated the pelvic frozen autograft removed in 2 years and 8 months after surgery because of soft tissue recurrence in pelvic floor. The autograft bone showed no evidence of revitalization and was non-viable with patchy inflammation, and no residual tumor. There was only fibrous union but the autograft bone remained mechanically stable.

Clinical Discussion: We confirmed the clearance of tumor cells with the treatment with liquid nitrogen. The union at the host-graft junction might be affected by the previous radiotherapy, the presence of infection, the small contact area limited by the anatomy, and the inadequate compression across the osteotomy interface with the fixation.

Conclusion: Frozen autograft treated by liquid nitrogen can be used safely for biological reconstructions after pelvic tumor excision.
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http://dx.doi.org/10.1016/j.ijscr.2021.105910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113746PMC
May 2021

Cardiac magnetic resonance imaging-negative cardiac sarcoidosis.

HeartRhythm Case Rep 2021 Mar 1;7(3):139-143. Epub 2021 Jan 1.

Division of Cardiology, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1016/j.hrcr.2020.11.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987903PMC
March 2021

Use of viscoelastic haemostatic assay in emergency and elective surgery.

Hong Kong Med J 2015 Feb 1;21(1):45-51. Epub 2014 Aug 1.

Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong.

Objectives: To review the current evidence for the use of viscoelastic haemostatic assays in different surgical settings including trauma, cardiac surgery, liver transplantation, as well as the monitoring of antiplatelet agents and anticoagulants prior to surgery.

Data Sources: PubMed database.

Study Selection: Key words for the literature search were "thromboelastography" or "ROTEM" in combination with "trauma", "antiplatelet", "cardiac surgery", "liver transplantation" or "anticoagulants".

Data Extraction: Original and major review articles related to the use of viscoelastic haemostatic assays.

Data Synthesis: Haemostatic function is a critical factor determining patient outcomes in emergency or elective surgery. The increasing use of antiplatelet agents and anticoagulants has potentially increased the risks of haemorrhages and the need for transfusion. Conventional coagulation tests have limitations in detecting haemostatic dysfunctions in subgroups of patients and are largely ineffective in diagnosing hyperfibrinolysis. The viscoelastic haemostatic assays are potentially useful point-of-care tools that provide information on clot formation, clot strength, and fibrinolysis, as well as to guide goal-directed transfusion and antifibrinolytic therapy. They may also be used to monitor antiplatelet and anticoagulant therapy. However, standardisation of techniques and reference ranges is required before these tests can be widely used in different clinical settings.

Conclusions: Viscoelastic haemostatic assays, as compared with conventional coagulation tests, are better for detecting coagulopathy and are the only tests that can provide rapid diagnosis of hyperfibrinolysis. Goal-directed administration of blood products based on the results of viscoelastic haemostatic assays was associated with reduction in allogeneic blood product transfusions in trauma, cardiac surgery, and liver transplantation cases. However, there is currently no evidence to support the routine use of viscoelastic haemostatic assays for monitoring platelet function prior to surgery.
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http://dx.doi.org/10.12809/hkmj134147DOI Listing
February 2015