Publications by authors named "Maxence V Nachury"

51Publications

Ubiquitin chains earmark GPCRs for BBSome-mediated removal from cilia.

J Cell Biol 2020 Dec;219(12)

Department of Ophthalmology, University of California, San Francisco, San Francisco, CA.

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December 2020

Near-atomic structures of the BBSome reveal the basis for BBSome activation and binding to GPCR cargoes.

Elife 2020 06 8;9. Epub 2020 Jun 8.

Department of Ophthalmology, University of California San Francisco, San Francisco, United States.

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June 2020

The Molecular Architecture of Native BBSome Obtained by an Integrated Structural Approach.

Structure 2019 09 11;27(9):1384-1394.e4. Epub 2019 Jul 11.

Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA; Laboratory of Molecular Electron Microscopy, The Rockefeller University, New York, NY 10065, USA. Electronic address:

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September 2019

Effects of α-tubulin acetylation on microtubule structure and stability.

Proc Natl Acad Sci U S A 2019 05 9;116(21):10366-10371. Epub 2019 May 9.

Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720;

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May 2019

Establishing and regulating the composition of cilia for signal transduction.

Nat Rev Mol Cell Biol 2019 07;20(7):389-405

Center of Human and Molecular Biology (ZHMB), Medical Biochemistry and Molecular Biology, Saarland University, Homburg, Germany.

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July 2019

The molecular machines that traffic signaling receptors into and out of cilia.

Curr Opin Cell Biol 2018 04 23;51:124-131. Epub 2018 Mar 23.

UCSF School of Medicine, Department of Ophthalmology, United States. Electronic address:

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April 2018

BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone.

J Cell Biol 2018 05 26;217(5):1847-1868. Epub 2018 Feb 26.

Department of Ophthalmology, University of California, San Francisco, San Francisco, CA

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May 2018

BORC Regulates the Axonal Transport of Synaptic Vesicle Precursors by Activating ARL-8.

Curr Biol 2017 Sep 17;27(17):2569-2578.e4. Epub 2017 Aug 17.

Howard Hughes Medical Institute, Department of Biology, Stanford University, 385 Serra Mall, Stanford, CA 94305, USA; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Beijing 100101, China. Electronic address:

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September 2017

Microtubules acquire resistance from mechanical breakage through intralumenal acetylation.

Science 2017 04;356(6335):328-332

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305-5345, USA.

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April 2017

Membrane traffic control by cytoskeletal and molecular machines.

Mol Biol Cell 2017 03;28(6):697-698

Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305.

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March 2017

Tubulin acetylation protects long-lived microtubules against mechanical ageing.

Nat Cell Biol 2017 04 27;19(4):391-398. Epub 2017 Feb 27.

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, California 94305, USA.

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April 2017

An Actin Network Dispatches Ciliary GPCRs into Extracellular Vesicles to Modulate Signaling.

Cell 2017 Jan 22;168(1-2):252-263.e14. Epub 2016 Dec 22.

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305-5345, USA. Electronic address:

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January 2017

Loss of the BBSome perturbs endocytic trafficking and disrupts virulence of Trypanosoma brucei.

Proc Natl Acad Sci U S A 2016 Jan 31;113(3):632-7. Epub 2015 Dec 31.

Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095; Molecular Biology Institute, University of California, Los Angeles, CA 90095

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January 2016

Proteomics of Primary Cilia by Proximity Labeling.

Dev Cell 2015 Nov 12;35(4):497-512. Epub 2015 Nov 12.

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305-5345, USA. Electronic address:

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November 2015

Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity.

ACS Chem Biol 2016 Jan 11;11(1):53-60. Epub 2015 Nov 11.

Laboratory of Chemistry and Cell Biology, Rockefeller University , New York City, New York 10065, United States.

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January 2016

Microtubules self-repair in response to mechanical stress.

Nat Mater 2015 Nov 7;14(11):1156-63. Epub 2015 Sep 7.

Laboratoire de Physiologie Cellulaire et Végétale, Institut de Recherche en Technologie et Science pour le Vivant, UMR5168, CEA/INRA/CNRS/UGA, 38054 Grenoble, France.

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November 2015

Analysis of soluble protein entry into primary cilia using semipermeabilized cells.

Methods Cell Biol 2015 14;127:203-21. Epub 2015 Feb 14.

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.

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January 2016