Max Essex

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Universal Testing and Treatment for HIV Infection in Botswana. Reply.

N Engl J Med 2019 11;381(22):2180

Harvard T.H. Chan School of Public Health, Boston, MA.

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http://dx.doi.org/10.1056/NEJMc1911065DOI Listing
November 2019

Comparative Safety of Antiretroviral Treatment Regimens in Pregnancy.

JAMA Pediatr 2017 10 2;171(10):e172222. Epub 2017 Oct 2.

Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamapediatrics.2017.2222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726309PMC
October 2017

Analysis of Viral Diversity in Relation to the Recency of HIV-1C Infection in Botswana.

PLoS One 2016 23;11(8):e0160649. Epub 2016 Aug 23.

Wellcome Trust Africa Centre for Health and Population Studies, Dorris Duke Medical Research Centre, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160649PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994946PMC
July 2017

Effect of co-trimoxazole on mortality in HIV-exposed but uninfected children in Botswana (the Mpepu Study): a double-blind, randomised, placebo-controlled trial.

Lancet Glob Health 2017 05;5(5):e491-e500

Botswana Harvard AIDS Institute Partnership for HIV Research and Education, Gaborone, Botswana; Department of Immunology and Infectious Diseases, Harvard T H Chan School of Public Health, Boston, MA, USA; Division of Infectious Disease, Beth Israel Deaconess Medical Center, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/S2214-109X(17)30143-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502726PMC
May 2017

The end of AIDS?

Authors:
Max Essex

Lancet Public Health 2017 05 10;2(5):e205-e206. Epub 2017 Apr 10.

Harvard T H Chan School of Public Health AIDS Initiative, Harvard University, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/S2468-2667(17)30070-1DOI Listing
May 2017

Pairwise diversity and tMRCA as potential markers for HIV infection recency.

Medicine (Baltimore) 2017 Feb;96(6):e6041

aDivision of Medical Virology, Stellenbosch University, Tygerberg, South Africa bBotswana-Harvard AIDS Institute Partnership, Gaborone, Botswana cAfrica Health Research Institute, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, Republic of South Africa dHarvard T.H. Chan School of Public Health, Boston, MA, USA eNational Health Laboratory Services (NHLS), Tygerberg Coastal, South Africa fResearch Department of Infection, University College London, London, United Kingdom gCollege of Health Sciences, University of KwaZulu-Natal, Durban, Republic of South Africa hDivision of Sleep Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1097/MD.0000000000006041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313003PMC
February 2017

Antiretroviral Therapy for the Prevention of HIV-1 Transmission.

N Engl J Med 2016 09 18;375(9):830-9. Epub 2016 Jul 18.

From the Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill (M.S.C., M.C.H., I.F.H., J.E.); the Divisions of Vaccine and Infectious Disease (Y.Q.C., X.C.Z.) and Public Health Science (Y.Q.C.) and the Statistical Center for HIV/AIDS Research and Prevention (L.C.), Fred Hutchinson Cancer Research Center, and the Department of Biostatistics, University of Washington (T.R.F.) - both in Seattle; FHI 360, Washington, DC (M.M.), and Durham, NC (T.G.); Y.R. Gaitonde Center for AIDS Research and Education, Chennai (N.K.), and National AIDS Research Institute, Pune (S.V.G.) - both in India; University of Zimbabwe, Harare (J.G.H.); College of Medicine-Johns Hopkins Project, Blantyre, Malawi (J.K.); Instituto de Pesquisa Clinica Evandro Chagas (B.G.) and Hospital Geral de Nova Iguacu and Laboratorio de AIDS e Imunologia Molecular-IOC/Fiocruz (J.H.S.P.), Rio de Janeiro, and Servico de Infectologia, Hospital Nossa Senhora da Conceicao/GHC, Porto Alegre (B.R.S.) - both in Brazil; Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand (S.C.); Fenway Institute (K.H.M.) and Harvard School of Public Health (M.E.) - both in Boston; the Departments of Pathology (S.H.E., E.P.-M., S.E.H.) and Medicine (A.D.R.), Johns Hopkins University School of Medicine, the Department of Epidemiology, Bloomberg School of Public Health (T.E.T.), and Johns Hopkins Bloomberg School of Public Health (D.D.C.), Baltimore, and the Division of AIDS (V.E., D.B.) and Laboratory of Immunoregulation (A.D.R.), National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda - both in Maryland; Botswana Harvard AIDS Institute, Gaborone (J.M.); Centers for Disease Control and Prevention (CDC) Division of HIV/AIDS Prevention/KEMRI-CDC Research and Public Health Collaboration HIV Research Branch, Kisumu, Kenya (L.A.M.); Perinatal HIV Research Unit (R.P.) and Clinical HIV Research Unit, Department of Medicine, Faculty of Health Scien

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049503PMC
http://dx.doi.org/10.1056/NEJMoa1600693DOI Listing
September 2016

Predictors of early breastfeeding cessation among HIV-infected women in Botswana.

Trop Med Int Health 2016 Aug 16;21(8):1013-1018. Epub 2016 Jun 16.

Botswana-Harvard AIDS Institute Partnership, Gaborone, Botswana.

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http://dx.doi.org/10.1111/tmi.12729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969096PMC
August 2016

Estimating the prevalence of transmitted HIV drug resistance using pooled samples.

Stat Methods Med Res 2016 04 1;25(2):917-35. Epub 2013 Feb 1.

Department of Biostatistics, Harvard School of Public Health, Boston, USA.

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http://dx.doi.org/10.1177/0962280212473514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994180PMC
April 2016

Reassuring Birth Outcomes With Tenofovir/Emtricitabine/Efavirenz Used for Prevention of Mother-to-Child Transmission of HIV in Botswana.

J Acquir Immune Defic Syndr 2016 Apr;71(4):428-36

*Beth Israel Deaconess Medical Center, Boston, MA; †Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; ‡Harvard School of Public Health, Boston, MA; §Faculty of Health Sciences, University of Botswana, Gaborone, Botswana; ‖Massachusetts General Hospital, Boston, MA; and ¶Brigham and Women's Hospital, Boston, MA.

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http://pdfs.journals.lww.com/jaids/2016/04010/Reassuring_Bir
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/QAI.0000000000000847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767604PMC
April 2016

Plasma Cytokine Levels in Chronic Asymptomatic HIV-1 Subtype C Infection as an Indicator of Disease Progression in Botswana: A Retrospective Case Control Study.

AIDS Res Hum Retroviruses 2016 Apr 21;32(4):364-9. Epub 2015 Oct 21.

1 Botswana-Harvard School of Public Health AIDS Initiative Partnership for HIV Research and Education (BHP) , Gaborone, Botswana .

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http://dx.doi.org/10.1089/AID.2015.0163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220552PMC
April 2016

In-utero triple antiretroviral exposure associated with decreased growth among HIV-exposed uninfected infants in Botswana.

AIDS 2016 Jan;30(2):211-20

aDepartments of Medicine and Pediatrics, Massachusetts General Hospital, Boston bDepartment of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA cBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana dDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA eElizabeth Glaser Pediatric AIDS Foundation, Harare, Zimbabwe fFaculty of Medicine, University of Botswana, Gabarone, Botswana gDivisions of Infectious Diseases and General Medicine, Department of Obstetrics, Gynecology, and Reproductive Science, Icahn School of Medicine, Mount Sinai, New York City, New York, USA hDepartment of Epidemiology, Harvard T.H. Chan School of Public Health iInfectious Disease Division, Brigham and Women's Hospital, Boston jDepartments of Global Health and Population, Nutrition and Epidemiology, Harvard T.H. Chan School of Public Health kBeth Israel Deaconess Medical Center, Infectious Diseases Department, Boston, Massachusetts, USA.

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http://pdfs.journals.lww.com/aidsonline/2016/01140/In_utero_
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/QAD.0000000000000895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685731PMC
January 2016

Identifying Recent HIV Infections: From Serological Assays to Genomics.

Viruses 2015 Oct 23;7(10):5508-24. Epub 2015 Oct 23.

Africa Centre for Health and Population Studies, Doris Duke Medical Research Centre, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban 4041, South Africa.

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http://dx.doi.org/10.3390/v7102887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632395PMC
October 2015

Immune activation markers in peripartum women in Botswana: association with feeding strategy and maternal morbidity.

PLoS One 2014 21;9(3):e89928. Epub 2014 Mar 21.

Harvard AIDS Initiative, Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, United States of America; Botswana-Harvard AIDS Institute, Gaborone, Botswana; Department of Medicine, Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0089928PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962339PMC
January 2015

Vitamin D insufficiency in HIV-infected pregnant women receiving antiretroviral therapy is not associated with morbidity, mortality or growth impairment in their uninfected infants in Botswana.

Pediatr Infect Dis J 2014 Nov;33(11):1141-7

From the *Departments of Internal Medicine and Pediatrics, Massachusetts General Hospital; †Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA; ‡Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; §Brigham and Women's Hospital, Infectious Disease Division; ¶Center for Biostatistics in AIDS Research, Harvard School of Public Health; ‖Department of Global Health and Population, Harvard School of Public Health; **Division of Endocrinology, Boston Children's Hospital; and ††Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA.

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https://insights.ovid.com/crossref?an=00006454-201411000-000
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http://dx.doi.org/10.1097/INF.0000000000000428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216630PMC
November 2014

Cotrimoxazole prophylaxis and risk of severe anemia or severe neutropenia in HAART-exposed, HIV-uninfected infants.

PLoS One 2013 23;8(9):e74171. Epub 2013 Sep 23.

Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, United States of America ; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana ; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0074171PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781096PMC
July 2014

Risk factors for mortality among human immunodeficiency virus-exposed and unexposed infants admitted to a neonatal intensive care unit in Botswana.

J Paediatr Child Health 2014 Mar 23;50(3):189-95. Epub 2013 Dec 23.

Division of Infectious Disease, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States; Botswana-Harvard AIDS Institute Partnership for HIV Research and Education, Gaborone, Botswana.

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http://dx.doi.org/10.1111/jpc.12454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310460PMC
March 2014

Unreported antiretroviral use by HIV-1-infected participants enrolling in a prospective research study.

J Acquir Immune Defic Syndr 2014 Feb;65(2):e90-4

*Department of Epidemiology, University of Washington, Seattle, WA †Division of Pharmacotherapy and Experimental Therapeutics, Echelman School of Pharmacy, University of North Carolina, Chapel Hill, NC Departments of ‡Global Health; §Medicine, University of Washington, Seattle, WA ‖Department of Medicine, Indiana University, Indianapolis, IN ¶Department of Immunology and Infectious Disease, Harvard School of Public Health, Harvard University, Cambridge, MA #Perinatal HIV Research Unit, University of Witwatersrand, Johannesburg, Republic of South Africa **Vaccine and Infectious Disease Institute, Fred Hutchinson Cancer Research Center, Seattle, WA ††Department of Pediatrics, University of Washington, Seattle, WA ‡‡Wits Reproductive Health and HIV Institute, University of Witwatersrand, Johannesburg, Republic of South Africa §§Department of Obstetrics and Gynecology, University of Nairobi and Kenyatta National Hospital, Nairobi, Kenya.

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http://dx.doi.org/10.1097/QAI.0b013e3182a2db02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898592PMC
February 2014

No clinically significant drug-resistance mutations in HIV-1 subtype C-infected women after discontinuation of NRTI-based or PI-based HAART for PMTCT in Botswana.

J Acquir Immune Defic Syndr 2013 Aug;63(5):572-7

*Botswana-Harvard AIDS Institute Partnership for HIV Research and Education, Gaborone, Botswana; †Department of Pathology, School of Medicine, University of Botswana, Gaborone, Botswana; ‡Harvard University, Cambridge, MA; §Department of Medicine and Pediatrics, Massachusetts General Hospital, Boston, MA; ‖Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA; ¶Department of Medicine, Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA; and #Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0b013e31829308f8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762949PMC
August 2013

Persistently elevated serum interleukin-6 predicts mortality among adults receiving combination antiretroviral therapy in Botswana: results from a clinical trial.

AIDS Res Hum Retroviruses 2013 Jul 9;29(7):993-9. Epub 2013 May 9.

Harvard School of Public Health AIDS Initiative, Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1089/aid.2012.0309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685692PMC
July 2013

Using HIV viral load to guide treatment-for-prevention interventions.

Curr Opin HIV AIDS 2012 Mar;7(2):117-24

Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/COH.0b013e32834fe8ffDOI Listing
March 2012

Increased risk of severe infant anemia after exposure to maternal HAART, Botswana.

J Acquir Immune Defic Syndr 2011 Apr;56(5):428-36

Department of Medicine, Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1097/QAI.0b013e31820bd2b6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112252PMC
April 2011

Strengthening biostatistics resources in sub-Saharan Africa: research collaborations through U.S. partnerships.

Stat Med 2011 Mar 12;30(7):695-708. Epub 2011 Jan 12.

National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, U.S.A.

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http://dx.doi.org/10.1002/sim.4144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562470PMC
March 2011

Minor resistant variants in nevirapine-exposed infants may predict virologic failure on nevirapine-containing ART.

J Clin Virol 2010 Jul 27;48(3):162-7. Epub 2010 Apr 27.

Department of Immunology and Infectious Diseases, Harvard School of Public Health, 651 Huntington Ave., Boston, MA 02115, United States.

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http://dx.doi.org/10.1016/j.jcv.2010.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909836PMC
July 2010

Perceptions of couple HIV counseling and testing in Botswana: a stakeholder analysis.

Patient Educ Couns 2010 Apr 13;79(1):120-3. Epub 2009 Aug 13.

Botswana-Harvard School of Public Health AIDS Initiative Partnership for HIV Research and Education, USA.

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http://dx.doi.org/10.1016/j.pec.2009.07.017DOI Listing
April 2010

HIV-1 Subtype C Phylodynamics in the Global Epidemic.

Viruses 2010 Jan 7;2(1):33-54. Epub 2010 Jan 7.

Department of Immunology and Infectious Diseases, Harvard School of Public Health AIDS Initiative, Harvard School of Public Health, Boston, MA, USA; E-Mail: (M.E.).

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http://www.mdpi.com/1999-4915/2/1/33
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http://dx.doi.org/10.3390/v2010033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185553PMC
January 2010

Adult combination antiretroviral therapy in sub-Saharan Africa: lessons from Botswana and future challenges.

HIV Ther 2009 Sep;3(5):501-526

Botswana-Harvard School of Public Health AIDS Initiative Partnership for HIV Research & Education (BHP), Gaborone, Botswana.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774911PMC
http://dx.doi.org/10.2217/hiv.09.35DOI Listing
September 2009

Five-year outcomes of initial patients treated in Botswana's National Antiretroviral Treatment Program.

AIDS 2008 Nov;22(17):2303-11

Botswana-Harvard School of Public Health AIDS Initiative Partnership for HIV Research and Education, Department of Immunology and Infectious Diseases, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/QAD.0b013e3283129db0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853026PMC
November 2008

Relative concordance of human immunodeficiency virus oligomeric and monomeric envelope in CCR5 coreceptor usage.

Virology 2008 Jan 22;370(2):443-50. Epub 2007 Oct 22.

Department of Immunology and Infectious Diseases, Harvard School of Public Health, 651 Huntington Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.virol.2007.09.009DOI Listing
January 2008

Infection of hematopoietic progenitor cells by HIV-1 subtype C, and its association with anemia in southern Africa.

Blood 2007 Nov 10;110(9):3143-9. Epub 2007 Aug 10.

Department of Immunology and Infectious Diseases, Harvard School of Public Health AIDS Initiative, 651 Huntington Avenue, Boston, MA 02115, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2007-04-08
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http://dx.doi.org/10.1182/blood-2007-04-086314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2200905PMC
November 2007

The role of herpes simplex virus type 2 and other genital infections in the acquisition of HIV-1 among high-risk women in northern Tanzania.

J Infect Dis 2007 May 15;195(9):1260-9. Epub 2007 Mar 15.

Department of Population and International Health, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1086/513566DOI Listing
May 2007

Noninfectious entry of HIV-1 into peripheral and brain macrophages mediated by the mannose receptor.

Proc Natl Acad Sci U S A 2007 Mar 14;104(12):5097-102. Epub 2007 Mar 14.

Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0611263104
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http://dx.doi.org/10.1073/pnas.0611263104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1821124PMC
March 2007

Predictors of herpes simplex virus type 2 prevalence and incidence among bar and hotel workers in Moshi, Tanzania.

J Infect Dis 2007 Feb 4;195(4):493-501. Epub 2007 Jan 4.

Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1086/510537DOI Listing
February 2007