Publications by authors named "Mauro Biffoni"

65Publications

COVID-19-Induced Modifications in the Tumor Microenvironment: Do They Affect Cancer Reawakening and Metastatic Relapse?

Front Oncol 2020 26;10:592891. Epub 2020 Oct 26.

Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.3389/fonc.2020.592891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649335PMC
October 2020

qSNE: Quadratic rate t-SNE optimizer with automatic parameter tuning for large data sets.

Bioinformatics 2020 Jul 14. Epub 2020 Jul 14.

Research Program in Systems Oncology, Research Programs Unit, Faculty of Medicine, University of Helsinki, Haartmaninkatu 8 (PO box 63), 00014 University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1093/bioinformatics/btaa637DOI Listing
July 2020

Two-Step Coimmunoprecipitation (TIP) Enables Efficient and Highly Selective Isolation of Native Protein Complexes.

Mol Cell Proteomics 2018 05 7;17(5):993-1009. Epub 2017 Dec 7.

From the ‡Department of Hematology and Oncology, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy;

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http://dx.doi.org/10.1074/mcp.O116.065920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930409PMC
May 2018

Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma.

Cell Stem Cell 2017 07 9;21(1):35-50.e9. Epub 2017 Jun 9.

Institute of General Pathology, Università Cattolica del Sacro Cuore and Fondazione Policlinico Universitario A. Gemelli, 00168 Rome, Italy; National Cancer Institute Regina Elena, 00144 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.04.009DOI Listing
July 2017

The clinical value of patient-derived glioblastoma tumorspheres in predicting treatment response.

Neuro Oncol 2017 Aug;19(8):1097-1108

Institute of Neurosurgery, Università Cattolica del Sacro Cuore, Rome, Italy; Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy; Institute of Pathology, Università Cattolica del Sacro Cuore, Rome, Italy; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana.

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http://dx.doi.org/10.1093/neuonc/now304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737323PMC
August 2017

Generation, Quantification, and Tracing of Metabolically Labeled Fluorescent Exosomes.

Methods Mol Biol 2016 ;1448:217-35

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.

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http://dx.doi.org/10.1007/978-1-4939-3753-0_16DOI Listing
January 2018

Molecular profiles of cancer stem-like cell populations in aggressive thyroid cancers.

Endocrine 2016 Jul 14;53(1):145-56. Epub 2015 Sep 14.

Dipartimento di Medicina Interna e Specialità Mediche, Università di Roma "Sapienza", Rome, Italy.

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http://dx.doi.org/10.1007/s12020-015-0739-yDOI Listing
July 2016

(1) H NMR spectroscopy of glioblastoma stem-like cells identifies alpha-aminoadipate as a marker of tumor aggressiveness.

NMR Biomed 2015 Mar 8;28(3):317-26. Epub 2015 Jan 8.

Department of Technology and Health, Istituto Superiore di Sanità, Rome, Italy; INFN Sezione di Roma, Rome, Italy.

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http://dx.doi.org/10.1002/nbm.3254DOI Listing
March 2015

miR-21 is overexpressed in NPM1-mutant acute myeloid leukemias.

Leuk Res 2015 Feb 18;39(2):221-8. Epub 2014 Nov 18.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2014.11.001DOI Listing
February 2015

1H NMR detects different metabolic profiles in glioblastoma stem-like cells.

NMR Biomed 2014 Feb 21;27(2):129-45. Epub 2013 Oct 21.

Department of Technology and Health and INFN Sanità Group, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.1002/nbm.3044DOI Listing
February 2014

BH4 domain of bcl-2 protein is required for its proangiogenic function under hypoxic condition.

Carcinogenesis 2013 Nov 8;34(11):2558-67. Epub 2013 Jul 8.

Experimental Chemotherapy Laboratory, Regina Elena National Cancer Institute, Rome 00158, Italy.

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http://dx.doi.org/10.1093/carcin/bgt242DOI Listing
November 2013

Prevention of chemotherapy-induced anemia and thrombocytopenia by constant administration of stem cell factor.

Clin Cancer Res 2011 Oct 25;17(19):6185-91. Epub 2011 Aug 25.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-11-1232DOI Listing
October 2011

Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells.

Nature 2010 Dec 21;468(7325):824-8. Epub 2010 Nov 21.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, Rome 00161, Italy.

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http://dx.doi.org/10.1038/nature09557DOI Listing
December 2010

Expression of the stem cell marker CD133 in recurrent glioblastoma and its value for prognosis.

Cancer 2011 Jan 30;117(1):162-74. Epub 2010 Aug 30.

Institute of Neurosurgery, Catholic University School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1002/cncr.25581DOI Listing
January 2011

Obesity hormone leptin induces growth and interferes with the cytotoxic effects of 5-fluorouracil in colorectal tumor stem cells.

Endocr Relat Cancer 2010 Sep 16;17(3):823-33. Epub 2010 Aug 16.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.1677/ERC-10-0083DOI Listing
September 2010

Thymosin beta4 targeting impairs tumorigenic activity of colon cancer stem cells.

FASEB J 2010 Nov 21;24(11):4291-301. Epub 2010 Jun 21.

Department of Hematology, Oncology, and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.1096/fj.10-159970DOI Listing
November 2010

New models for cancer research: human cancer stem cell xenografts.

Curr Opin Pharmacol 2010 Aug 17;10(4):380-4. Epub 2010 Jun 17.

Dipartimento Ematologia, Oncologia e Medicina Molecolare, Istituto Superiore di Sanità, Viale Regina Elena 299, Roma, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S147148921000053
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http://dx.doi.org/10.1016/j.coph.2010.05.002DOI Listing
August 2010

Caveolin-1 tumor-promoting role in human melanoma.

Int J Cancer 2009 Oct;125(7):1514-22

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena, Rome, Italy.

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http://dx.doi.org/10.1002/ijc.24451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805039PMC
October 2009

High sensitivity of ovarian cancer cells to the synthetic triterpenoid CDDO-Imidazolide.

Cancer Lett 2009 Sep 11;282(2):214-28. Epub 2009 Apr 11.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.canlet.2009.03.018DOI Listing
September 2009

MicroRNA 223-dependent expression of LMO2 regulates normal erythropoiesis.

Haematologica 2009 Apr 10;94(4):479-86. Epub 2009 Mar 10.

Dept. of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.3324/haematol.2008.002345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663611PMC
April 2009

MicroRNA 155 modulates megakaryopoiesis at progenitor and precursor level by targeting Ets-1 and Meis1 transcription factors.

Br J Haematol 2008 Nov;143(4):570-80

Department of Haematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.

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http://doi.wiley.com/10.1111/j.1365-2141.2008.07382.x
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http://dx.doi.org/10.1111/j.1365-2141.2008.07382.xDOI Listing
November 2008

A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis.

Nat Cell Biol 2008 Jul 22;10(7):788-801. Epub 2008 Jun 22.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy.

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http://dx.doi.org/10.1038/ncb1741DOI Listing
July 2008

Isolation and characterization of CD146+ multipotent mesenchymal stromal cells.

Exp Hematol 2008 Aug 27;36(8):1035-46. Epub 2008 May 27.

Department of Hematology, Oncology, and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.1016/j.exphem.2008.03.004DOI Listing
August 2008

Methylation damage response in hematopoietic progenitor cells.

DNA Repair (Amst) 2007 Aug 15;6(8):1170-8. Epub 2007 May 15.

Section of Experimental Carcinogenesis, Department of Environment and Primary Prevention, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.1016/j.dnarep.2007.03.024DOI Listing
August 2007

Transferrin receptor 2 is frequently expressed in human cancer cell lines.

Blood Cells Mol Dis 2007 Jul-Aug;39(1):82-91. Epub 2007 Apr 10.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.bcmd.2007.02.003DOI Listing
September 2007

A small molecule Smac mimic potentiates TRAIL-mediated cell death of ovarian cancer cells.

Gynecol Oncol 2007 May 9;105(2):481-92. Epub 2007 Feb 9.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.ygyno.2007.01.011DOI Listing
May 2007

Proteasome inhibitors sensitize ovarian cancer cells to TRAIL induced apoptosis.

Apoptosis 2007 Apr;12(4):635-55

Medical Oncology Section, Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1007/s10495-006-0025-9DOI Listing
April 2007

Identification and expansion of human colon-cancer-initiating cells.

Nature 2007 Jan 19;445(7123):111-5. Epub 2006 Nov 19.

Department of Hematology and Oncology, Istituto Superiore di Sanità, Viale Regina Elena 299, Rome 00161, Italy.

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http://dx.doi.org/10.1038/nature05384DOI Listing
January 2007

Podocalyxin is expressed in normal and leukemic monocytes.

Blood Cells Mol Dis 2006 Nov-Dec;37(3):218-25. Epub 2006 Oct 23.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.

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http://dx.doi.org/10.1016/j.bcmd.2006.09.001DOI Listing
February 2007

Multiple members of the TNF superfamily contribute to IFN-gamma-mediated inhibition of erythropoiesis.

J Immunol 2005 Aug;175(3):1464-72

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.4049/jimmunol.175.3.1464DOI Listing
August 2005