Publications by authors named "Maurizio Romano"

74Publications

From basic research to the clinic: innovative therapies for ALS and FTD in the pipeline.

Mol Neurodegener 2020 06 1;15(1):31. Epub 2020 Jun 1.

International Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, 34149, Trieste, Italy.

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http://dx.doi.org/10.1186/s13024-020-00373-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268618PMC
June 2020

Synthesis, Cytotoxicity Evaluation, and Computational Insights of Novel 1,4-Diazepane-Based Sigma Ligands.

ACS Med Chem Lett 2020 May 16;11(5):651-656. Epub 2019 Dec 16.

Department of Chemical and Pharmaceutical Sciences, P.le Europa 1-Via Giorgieri 1, University of Trieste, 34127 Trieste, Italy.

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http://dx.doi.org/10.1021/acsmedchemlett.9b00524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236030PMC
May 2020

Discovery of new potent dual sigma receptor/GluN2b ligands with antioxidant property as neuroprotective agents.

Eur J Med Chem 2019 Oct 8;180:268-282. Epub 2019 Jul 8.

Department of Chemistry and Pharmaceutical Sciences, Piazzale Europa 1- Via Giorgieri 1, University of Trieste, 34127, Trieste, Italy.

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http://dx.doi.org/10.1016/j.ejmech.2019.07.012DOI Listing
October 2019

New piperidine-based derivatives as sigma receptor ligands. Synthesis and pharmacological evaluation.

Bioorg Med Chem Lett 2018 10 15;28(19):3206-3209. Epub 2018 Aug 15.

Department of Chemistry and Pharmaceutical Sciences, Piazzale Europa 1, University of Trieste, 34127 Trieste, Italy.

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http://dx.doi.org/10.1016/j.bmcl.2018.08.016DOI Listing
October 2018

Essential role of hippocampal noradrenaline in the regulation of spatial working memory and TDP-43 tissue pathology.

J Comp Neurol 2018 05 6;526(7):1131-1147. Epub 2018 Feb 6.

B.R.A.I.N. Lab for Neurogenesis and Repair, Department of Life Sciences, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.1002/cne.24397DOI Listing
May 2018

Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells.

Nucleic Acids Res 2017 Jul;45(13):8026-8045

International Centre for Genetic Engineering and Biotechnology (ICGEB), 34149 Trieste, Italy.

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http://dx.doi.org/10.1093/nar/gkx477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570092PMC
July 2017

HPV epigenetic mechanisms related to Oropharyngeal and Cervix cancers.

Cancer Biol Ther 2018 14;19(10):850-857. Epub 2018 May 14.

c Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, Temple University , Philadelphia , PA , USA.

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http://dx.doi.org/10.1080/15384047.2017.1310349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300347PMC
September 2019

Liver radiofrequency ablation as emergency treatment for a ruptured hepatocellular carcinoma: a case report.

J Med Case Rep 2017 Mar 1;11(1):54. Epub 2017 Mar 1.

Department of Surgery, Oncology and Gastroenterology (DISCOG), Hepatobiliary Surgery and Liver Transplantation, Padua University, Padua, Italy.

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http://dx.doi.org/10.1186/s13256-017-1199-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331708PMC
March 2017

Erratum to: A Regenerative Approach with Dermal Micrografts in the Treatment of Chronic Ulcers.

Stem Cell Rev Rep 2017 Feb;13(1):149

Multidisciplinary Department of Medical-Surgical and Dental Specialties, Second University of Naples, Miraglia Square, 80122, Naples, Italy.

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http://dx.doi.org/10.1007/s12015-016-9698-9DOI Listing
February 2017

A Regenerative Approach with Dermal Micrografts in the Treatment of Chronic Ulcers.

Stem Cell Rev Rep 2017 Feb;13(1):139-148

Multidisciplinary Department of Medical-Surgical and Dental Specialties, Second University of Naples, Miraglia Square, 80122, Naples, Italy.

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http://dx.doi.org/10.1007/s12015-016-9692-2DOI Listing
February 2017

The role of adipose stem cells in inflammatory bowel disease: From biology to novel therapeutic strategies.

Cancer Biol Ther 2016 09 14;17(9):889-98. Epub 2016 Jul 14.

b Department of Surgery , Oncology and Gastroenterology, Hepatobiliary Surgery and Liver Transplantation, Padua University Hospital , Padua , Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036414PMC
http://dx.doi.org/10.1080/15384047.2016.1210741DOI Listing
September 2016

New neurogenic lipoic-based hybrids as innovative Alzheimer's drugs with σ-1 agonism and β-secretase inhibition.

Future Med Chem 2016 07 12;8(11):1191-207. Epub 2016 Jul 12.

Instituto de Química Médica (IQM-CSIC), C/Juan de la Cierva 3, 28006-Madrid, Spain.

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http://dx.doi.org/10.4155/fmc-2016-0036DOI Listing
July 2016

Computer-assisted design, synthesis, binding and cytotoxicity assessments of new 1-(4-(aryl(methyl)amino)butyl)-heterocyclic sigma 1 ligands.

Eur J Med Chem 2016 Oct 3;121:712-726. Epub 2016 Jun 3.

Molecular Simulation Engineering (MOSE) Laboratory, DEA, Piazzale Europa 1, University of Trieste, 34127 Trieste, Italy.

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http://dx.doi.org/10.1016/j.ejmech.2016.06.001DOI Listing
October 2016

Antimycobacterial activity of new N(1)-[1-[1-aryl-3-[4-(1H-imidazol-1-yl)phenyl]-3-oxo]propyl]-pyridine-2-carboxamidrazone derivatives.

Bioorg Med Chem Lett 2016 07 19;26(14):3287-3290. Epub 2016 May 19.

Department of Life and Enviromental Sciences, Via Porcell 4, University of Cagliari, 09124 Cagliari, Italy.

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http://dx.doi.org/10.1016/j.bmcl.2016.05.053DOI Listing
July 2016

From Inflammation to Cancer in Inflammatory Bowel Disease: Molecular Perspectives.

Anticancer Res 2016 Apr;36(4):1447-60

Department of Surgery, Oncology and Gastroenterology, Hepatobiliary Surgery and Liver Transplantation, Padua University Hospital, Padua, Italy.

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April 2016

TBPH/TDP-43 modulates translation of Drosophila futsch mRNA through an UG-rich sequence within its 5'UTR.

Brain Res 2016 09 18;1647:50-56. Epub 2016 Feb 18.

International Centre for Genetic Engineering and Biotechnology (ICGEB), 34012 Trieste, Italy.

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http://dx.doi.org/10.1016/j.brainres.2016.02.022DOI Listing
September 2016

Tumor Microenvironment Versus Cancer Stem Cells in Cholangiocarcinoma: Synergistic Effects?

J Cell Physiol 2016 Apr 22;231(4):768-76. Epub 2015 Sep 22.

Department of Surgery, Oncology and Gastroenterology, Hepatobiliary Surgery and Liver Transplantation, Padua University Hospital, Padua, Italy.

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http://dx.doi.org/10.1002/jcp.25190DOI Listing
April 2016

Expression of cancer stem cell biomarkers as a tool for a correct therapeutic approach to hepatocellular carcinoma.

Oncoscience 2015 15;2(5):443-456. Epub 2015 May 15.

Department of Surgery, Oncology and Gastroenterology, Hepatobiliary Surgery and Liver Transplantation, Padua University Hospital, Padua (Italy).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468330PMC
http://dx.doi.org/10.18632/oncoscience.163DOI Listing
June 2015

Knockdown of MVK does not lead to changes in NALP3 expression or activation.

J Inflamm (Lond) 2015 31;12. Epub 2015 Jan 31.

Institute for Maternal and Child Health - IRCCS "Burlo Garofolo", via dell'Istria 65/1, 34137 Trieste, Italy ; Department of Life Sciences, University of Trieste, Via A. Valerio 28, 34127 Trieste, Italy.

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http://dx.doi.org/10.1186/s12950-015-0048-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320511PMC
February 2015

Totally laparoscopic caudate lobe resection: technical aspects and literature review.

Surg Laparosc Endosc Percutan Tech 2014 Dec;24(6):e233-6

*General Surgery and Organ Transplantation, Hepatobiliary Surgery and Liver Transplant Unit †Department of Anesthesiology, Azienda Università di Padova, Padova ‡Department of Surgery, HPB and Advanced Minimally Invasive Surgery, Policlinico di Abano Terme, Italy.

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http://dx.doi.org/10.1097/01.sle.0000442525.26905.6dDOI Listing
December 2014

The role of CD44+/CD24-/low biomarker for screening, diagnosis and monitoring of breast cancer.

Oncol Rep 2014 Mar 23;31(3):1127-32. Epub 2013 Dec 23.

Department of Experimental Oncology, National Cancer Institute, G. Pascale, Naples, Italy.

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http://dx.doi.org/10.3892/or.2013.2943DOI Listing
March 2014

Role of pseudoexons and pseudointrons in human cancer.

Int J Cell Biol 2013 24;2013:810572. Epub 2013 Sep 24.

Department of Life Sciences, University of Trieste, Via A. Valerio 28, 34127 Trieste, Italy.

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http://dx.doi.org/10.1155/2013/810572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800588PMC
June 2014

Targeting RNA binding proteins involved in neurodegeneration.

J Biomol Screen 2013 Oct 16;18(9):967-83. Epub 2013 Aug 16.

1Department of Life Sciences, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.1177/1087057113497256DOI Listing
October 2013

TDP-43 high throughput screening analyses in neurodegeneration: advantages and pitfalls.

Mol Cell Neurosci 2013 Sep 14;56:465-74. Epub 2013 Mar 14.

International Centre for Genetic Engineering and Biotechnology (ICGEB) 34012 Trieste, Italy.

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http://dx.doi.org/10.1016/j.mcn.2013.03.001DOI Listing
September 2013

Drosophila Answers to TDP-43 Proteinopathies.

J Amino Acids 2012 18;2012:356081. Epub 2012 Apr 18.

Department of Life Sciences, University of Trieste, Via A. Valerio 28, 34127 Trieste, Italy.

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http://dx.doi.org/10.1155/2012/356081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337594PMC
August 2012

[The 29th National Congress of the Italian Society of Surgical Endocrinology, Mondello (Palermo), June 24-26, 2010].

Authors:
Maurizio Romano

G Chir 2010 Nov-Dec;31(11-12):577

Societá Italiana di Endocrinochirurgia

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February 2011

TDP-43 regulates its mRNA levels through a negative feedback loop.

EMBO J 2011 Jan 3;30(2):277-88. Epub 2010 Dec 3.

Department of Molecular Pathology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy.

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http://dx.doi.org/10.1038/emboj.2010.310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025456PMC
January 2011

G runs in cystathionine beta-synthase c.833C/c.844_845ins68 mRNA are splicing silencers of pathogenic 3' splice sites.

Authors:
Maurizio Romano

Biochim Biophys Acta 2010 Aug 26;1799(8):568-74. Epub 2010 Jun 26.

Department of Life Sciences, University of Trieste, Via A. Valerio 28, 34127 Trieste, Italy.

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http://dx.doi.org/10.1016/j.bbagrm.2010.06.006DOI Listing
August 2010

Nuclear factor TDP-43 can affect selected microRNA levels.

FEBS J 2010 May;277(10):2268-81

International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.

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http://dx.doi.org/10.1111/j.1742-4658.2010.07643.xDOI Listing
May 2010

Functional mapping of the interaction between TDP-43 and hnRNP A2 in vivo.

Nucleic Acids Res 2009 Jul 8;37(12):4116-26. Epub 2009 May 8.

International Centre for Genetic Engineering and Biotechnology (ICGEB), 34012 Trieste, Italy.

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http://dx.doi.org/10.1093/nar/gkp342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709582PMC
July 2009

Dissecting the splicing mechanism of the Drosophila editing enzyme; dADAR.

Nucleic Acids Res 2009 Apr 19;37(5):1663-71. Epub 2009 Jan 19.

International Centre for Genetic Engineering and Biotechnology, Padriciano 99, I-34012, Italy.

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http://dx.doi.org/10.1093/nar/gkn1080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655694PMC
April 2009

Thrombopoietin and its splicing variants: structure and functions in thrombopoiesis and beyond.

Biochim Biophys Acta 2008 Jul-Aug;1782(7-8):427-32. Epub 2008 Apr 8.

International Centre for Genetic Engineering and Biotechnology, Padriciano 99, I-34012, Trieste, Italy.

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http://dx.doi.org/10.1016/j.bbadis.2008.03.007DOI Listing
August 2008

Origin and evolution of the c.844_845ins68/c.833T>C mutations within the cystathionine beta-synthase gene in great apes.

FEBS Lett 2008 Feb 15;582(3):423-6. Epub 2008 Jan 15.

International Centre for Genetic Engineering and Biotechnology, Padriciano 99, I-34012 Trieste, Italy.

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http://dx.doi.org/10.1016/j.febslet.2007.12.038DOI Listing
February 2008

Complex splicing control of the human Thrombopoietin gene by intronic G runs.

Nucleic Acids Res 2007 7;35(1):132-42. Epub 2006 Dec 7.

International Centre for Genetic Engineering and Biotechnology, Padriciano 99 I-34012, Trieste, Italy.

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http://dx.doi.org/10.1093/nar/gkl965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802585PMC
February 2007

Massive gastric ulceration after transarterial chemoembolization for hepatocellular carcinoma.

Gastrointest Endosc 2006 Apr;63(4):718-20

Istituto di Medicina Interna ed Epatologia, Seconda Università di Napoli, Naples, Italy.

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http://dx.doi.org/10.1016/j.gie.2005.10.021DOI Listing
April 2006

Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene.

Nucleic Acids Res 2005 27;33(18):6000-10. Epub 2005 Oct 27.

International Centre for Genetic Engineering and Biotechnology, Padriciano 99, I-34012 Trieste, Italy.

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http://dx.doi.org/10.1093/nar/gki897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1270946PMC
November 2005

Genetic studies on myeloperoxidase deficiency in Italy.

Jpn J Infect Dis 2004 Oct;57(5):S10-2

Department of Physiology and Pathology, University of Trieste, Trieste, Italy.

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October 2004

CT guided percutaneous fine needle biopsy of small lung lesions in outpatients. Safety and efficacy of the procedure compared to inpatients.

Radiol Med 2004 Sep;108(3):275-82

Dipartimento Assistenziale di Radiologia e Radioterapia, Università degli Studi Federico II, Naples.

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September 2004

Vertebrate yolk proteins: a review.

Mol Reprod Dev 2004 Sep;69(1):109-16

Department of Evolutionary and Comparative Biology, University Federico II, Via Mezzocannone, 8-80134 Naples, Italy.

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http://dx.doi.org/10.1002/mrd.20146DOI Listing
September 2004

An exonic splicing enhancer offsets the atypical GU-rich 3' splice site of human apolipoprotein A-II exon 3.

J Biol Chem 2004 Sep 7;279(38):39331-9. Epub 2004 Jul 7.

International Centre for Genetic Engineering and Biotechnology, Padriciano 99, I-34012 Trieste, Italy.

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http://dx.doi.org/10.1074/jbc.M405566200DOI Listing
September 2004

Genetic characterization of myeloperoxidase deficiency in Italy.

Hum Mutat 2004 May;23(5):496-505

International Centre for Genetic Engineering and Biotechnology, Trieste, Italy.

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http://dx.doi.org/10.1002/humu.20027DOI Listing
May 2004

Ovarian follicle cells in torpedo marmorata synthesize vitellogenin.

Mol Reprod Dev 2004 Apr;67(4):424-9

Department of Evolutive and Comparative Biology, University of Naples Federico II, Naples, Italy.

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http://dx.doi.org/10.1002/mrd.20036DOI Listing
April 2004

Partial splenic embolization in patients with idiopathic portal hypertension.

Eur J Radiol 2004 Mar;49(3):268-73

Department of Radiology and Radiotherapy, University 'Federico II', 5, Via Pansini, 80131 Naples, Italy.

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http://dx.doi.org/10.1016/S0720-048X(03)00134-7DOI Listing
March 2004

Recanalization and stenting of right aortoiliac bifurcation occlusion with a malpositioned contralateral stent already in place: a technical note.

Radiol Med 2003 Mar;105(3):242-6

Dipartimento Assistenziale di Radiologia e Radioterapia, Università Federico II, Napoli, Italy.

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March 2003

CT detection of pulmonary embolism in a patient with negative pulmonary angiogram.

Radiol Med 2003 Mar;105(3):234-7

Dipartimento Assistenziale di Radiologia e Radioterapia, Università Federico II, Napoli, Italy.

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March 2003

Chemoembolization for hepatocellular carcinoma: effect of intraarterial lidocaine in peri- and post-procedural pain and hospitalization.

Radiol Med 2003 Apr;105(4):350-5

Dipartimento Assistenziale di Radiologia e Radioterapia, Università Federico II, Naples, Italy.

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April 2003

Upper thoracic sympathetic chain neurolysis under CT guidance. A two year follow-up in patients with palmar and axillary hyperhidrosis.

Radiol Med 2002 Nov-Dec;104(5-6):421-5

Dipartimento Assistenziale di Radiologia e Radioterapia, Università Federico II, Napoli, Italy.

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April 2003

An ultrastructural study on the vitellogenesis in the spotted ray Torpedo marmorata.

Gen Comp Endocrinol 2002 Oct;128(3):171-9

Department of Evolutive and Comparative Biology, University of Naples Federico II, 80134 Naples, Italy.

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http://dx.doi.org/10.1016/s0016-6480(02)00542-7DOI Listing
October 2002

Vitellogenin precursors in the liver of the oviparous lizard, Podarcis sicula.

Mol Reprod Dev 2002 Nov;63(3):349-54

Department of Evolutionary and Comparative Biology, University Federico II, Napoli, Italy.

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http://dx.doi.org/10.1002/mrd.90019DOI Listing
November 2002

Lipovitellins and phosvitins of the fertilized eggs during embryo growth in the oviparous lizard Podarcis sicula.

Mol Reprod Dev 2002 Nov;63(3):341-8

Department of Evolutionary and Comparative Biology, University Federico II, Via Mezzocannone, Napoli, Italy.

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http://dx.doi.org/10.1002/mrd.90018DOI Listing
November 2002

Regulation of 3' splice site selection in the 844ins68 polymorphism of the cystathionine Beta -synthase gene.

J Biol Chem 2002 Nov 12;277(46):43821-9. Epub 2002 Sep 12.

International Centre for Genetic Engineering and Biotechnology, Padriciano 99, Trieste I-34012, Italy.

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http://dx.doi.org/10.1074/jbc.M208107200DOI Listing
November 2002

Dual-phase versus single-phase helical CT to detect and assess resectability of pancreatic carcinoma.

AJR Am J Roentgenol 2002 Jun;178(6):1473-9

Department of Radiology, University "Federico II," Via Pansini 5, 80131 Napoli, Italy.

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http://dx.doi.org/10.2214/ajr.178.6.1781473DOI Listing
June 2002

Oocyte growth and follicular hierarchy may be locally controlled by an inhibin-like protein in the lizard Podarcis sicula.

J Exp Zool 2002 Jan;292(1):96-102

Department of Evolutionary and Comparative Biology, University of Naples "Federico II," 80134 Naples, Italy.

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http://dx.doi.org/10.1002/jez.1146DOI Listing
January 2002