Publications by authors named "Maurizio Fava"

85Publications

Long-term outcome in outpatients with depression treated with acute and maintenance intravenous ketamine: A retrospective chart review.

J Affect Disord 2020 Nov 20;276:660-666. Epub 2020 Jul 20.

Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, 1 Bowdoin Square, 6th Floor, Boston, MA 02114, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2020.07.089DOI Listing
November 2020

Long-term outcome in outpatients with depression treated with acute and maintenance intravenous ketamine: A retrospective chart review.

J Affect Disord 2020 Nov 20;276:660-666. Epub 2020 Jul 20.

Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, 1 Bowdoin Square, 6th Floor, Boston, MA 02114, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2020.07.089DOI Listing
November 2020

PET imaging of neurotransmission using direct parametric reconstruction.

Neuroimage 2020 Jul 15;221:117154. Epub 2020 Jul 15.

Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2020.117154DOI Listing
July 2020

Low-Dose Testosterone Augmentation for Antidepressant-Resistant Major Depressive Disorder in Women: An 8-Week Randomized Placebo-Controlled Study.

Am J Psychiatry 2020 Jul 14:appiajp202019080844. Epub 2020 Jul 14.

Neuroendocrine Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston (Dichtel, Kimball, Miller); Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston (Nyer, Mischoulon, Deckersbach, Dougherty, Yeung, Cassano, Hahn, Farabaugh, Pedrelli, Trinh, Dording, Cusin, Papakostas, Chang, Fisher, Shapero, Chen, Fava); Department of Psychiatry, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston (Brady); Biostatistics Center, Massachusetts General Hospital, Boston (Schoenfeld); Butler Hospital and Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Medicine, Brown University, Providence, R.I. (Carpenter, Tyrka, Price); Neuroendocrine Unit, Department of Medicine, Massachusetts General Hospital, Boston (Rao); Mayo Clinic Endocrine Laboratory, Rochester, Minn. (Singh).

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http://dx.doi.org/10.1176/appi.ajp.2020.19080844DOI Listing
July 2020

Randomized, controlled, participant- and rater-blind trial of pharmacogenomic test-guided treatment versus treatment as usual for major depressive disorder.

Depress Anxiety 2020 Sep 7;37(9):834-841. Epub 2020 May 7.

Clinical Research & Development and Medical Affairs, Genomind, Inc., King of Prussia, Pennsylvania.

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http://dx.doi.org/10.1002/da.23029DOI Listing
September 2020

Improvement of sexual functioning during treatment of MDD with adjunctive pimavanserin: A secondary analysis.

Depress Anxiety 2020 May 17;37(5):485-495. Epub 2020 Apr 17.

Medical Department, ACADIA Pharmaceuticals Inc., San Diego, California.

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http://dx.doi.org/10.1002/da.23017DOI Listing
May 2020

Anger attacks are associated with persistently elevated irritability in MDD: findings from the EMBARC study.

Psychol Med 2020 Mar 6:1-9. Epub 2020 Mar 6.

Center for Depression Research and Clinical Care, Peter O'Donnell Jr. Brain Institute, UT Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1017/S0033291720000112DOI Listing
March 2020

Success and efficiency of phase 2/3 adjunctive trials for MDD funded by industry: a systematic review.

Mol Psychiatry 2020 Sep 27;25(9):1967-1974. Epub 2020 Jan 27.

Clinical Trials Network and Institute, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41380-020-0646-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473846PMC
September 2020

Predictive factors of diagnostic conversion from major depressive disorder to bipolar disorder in young adults ages 19-34: A nationwide population study in South Korea.

J Affect Disord 2020 Mar 7;265:52-58. Epub 2020 Jan 7.

Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135770, South Korea; Department of Health Sciences & Technology, Department of Medical Device Management & Research, and Department of Clinical Research Design & Evaluation, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Seoul, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2020.01.009DOI Listing
March 2020

Elevated Amygdala Activity in Young Adults With Familial Risk for Depression: A Potential Marker of Low Resilience.

Biol Psychiatry Cogn Neurosci Neuroimaging 2020 02 6;5(2):194-202. Epub 2019 Nov 6.

Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts; Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts.

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http://dx.doi.org/10.1016/j.bpsc.2019.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448615PMC
February 2020

Rising placebo response rates threaten the validity of antipsychotic meta-analyses.

Ann Clin Psychiatry 2019 11;31(4):249-259

Department of Psychiatry, Massachusetts General Hospital, Wang 8 Outpatient Psychiatry Clinic, MA, USA. E-MAIL:

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November 2019

Pre-treatment peripheral biomarkers associated with treatment response in panic symptoms in patients with major depressive disorder and panic disorder: A 12-week follow-up study.

Compr Psychiatry 2019 11 19;95:152140. Epub 2019 Oct 19.

Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; Department of Health Sciences & Technology, Department of Medical Device Management & Research, and Department of Clinical Research Design & Evaluation, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.comppsych.2019.152140DOI Listing
November 2019

Pre-treatment peripheral biomarkers associated with treatment response in panic symptoms in patients with major depressive disorder and panic disorder: A 12-week follow-up study.

Compr Psychiatry 2019 11 19;95:152140. Epub 2019 Oct 19.

Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; Department of Health Sciences & Technology, Department of Medical Device Management & Research, and Department of Clinical Research Design & Evaluation, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.comppsych.2019.152140DOI Listing
November 2019

WITHDRAWN: Size Does Matter, But It Isn't Everything: The Challenge of Modest Treatment Effects in Chronic Pain Clinical Trials.

J Pain 2019 Sep 30. Epub 2019 Sep 30.

Department of Anesthesiology and Perioperative Medicine, University of Rochester Medical Center, Rochester, New York; Department of Psychiatry, University of Rochester Medical Center, Rochester, New York; Department of Neurology, University of Rochester Medical Center, Rochester, New York; Center for Health + Technology, University of Rochester Medical Center, Rochester, New York.

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http://dx.doi.org/10.1016/j.jpain.2019.09.008DOI Listing
September 2019

Optimal dosing of antidepressant drugs.

Lancet Psychiatry 2019 10;6(10):805-806

Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1016/S2215-0366(19)30303-7DOI Listing
October 2019

Effect of Intrinsic Patterns of Functional Brain Connectivity in Moderating Antidepressant Treatment Response in Major Depression.

Am J Psychiatry 2020 02 20;177(2):143-154. Epub 2019 Sep 20.

Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas (Chin Fatt, Jha, Cooper, South, Grannemann, Carmody, Greer, Kurian, Trivedi); Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York (Jha); Department of Psychiatry and Behavioral Sciences and Stanford Neurosciences Institute, Stanford University, Stanford, Calif. (Fonzo, Etkin); Mental Illness Research, Education, and Clinical Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, Calif. (Fonzo, Etkin); Department of Psychiatry, Massachusetts General Hospital, Boston (Fava); New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York (McGrath, Adams, Weissman); Department of Psychiatry, University of Michigan School of Medicine, Ann Arbor (McInnis); Department of Psychiatry and Behavioral Science and Department of Radiology, Stony Brook University, Stony Brook, N.Y. (Parsey); and Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Phillips).

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http://dx.doi.org/10.1176/appi.ajp.2019.18070870DOI Listing
February 2020

Effect of Intrinsic Patterns of Functional Brain Connectivity in Moderating Antidepressant Treatment Response in Major Depression.

Am J Psychiatry 2020 02 20;177(2):143-154. Epub 2019 Sep 20.

Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas (Chin Fatt, Jha, Cooper, South, Grannemann, Carmody, Greer, Kurian, Trivedi); Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York (Jha); Department of Psychiatry and Behavioral Sciences and Stanford Neurosciences Institute, Stanford University, Stanford, Calif. (Fonzo, Etkin); Mental Illness Research, Education, and Clinical Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, Calif. (Fonzo, Etkin); Department of Psychiatry, Massachusetts General Hospital, Boston (Fava); New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York (McGrath, Adams, Weissman); Department of Psychiatry, University of Michigan School of Medicine, Ann Arbor (McInnis); Department of Psychiatry and Behavioral Science and Department of Radiology, Stony Brook University, Stony Brook, N.Y. (Parsey); and Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Phillips).

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http://dx.doi.org/10.1176/appi.ajp.2019.18070870DOI Listing
February 2020

Ratio of plasma BDNF to leptin levels are associated with treatment response in major depressive disorder but not in panic disorder: A 12-week follow-up study.

J Affect Disord 2019 12 14;259:349-354. Epub 2019 Aug 14.

Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; Department of Health Sciences & Technology, Department of Medical Device Management & Research, and Department of Clinical Research Design & Evaluation, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2019.08.021DOI Listing
December 2019

Increased Morbidity of Major Depressive Disorder After Thyroidectomy: A Nationwide Population-Based Study in South Korea.

Thyroid 2019 12 19;29(12):1713-1722. Epub 2019 Sep 19.

Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1089/thy.2019.0091DOI Listing
December 2019

Longer-term open-label study of adjunctive riluzole in treatment-resistant depression.

J Affect Disord 2019 11 2;258:102-108. Epub 2019 Jul 2.

Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, 1 Bowdoin Square, 6th Floor, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2019.06.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710149PMC
November 2019

Model-Informed Approach to Assess the Treatment Effect Conditional to the Level of Placebo Response.

Clin Pharmacol Ther 2019 12 30;106(6):1253-1260. Epub 2019 Aug 30.

Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/cpt.1584DOI Listing
December 2019

Effect of Korean Red Ginseng in individuals exposed to high stress levels: a 6-week, double-blind, randomized, placebo-controlled trial.

J Ginseng Res 2019 Jul 8;43(3):402-407. Epub 2018 Mar 8.

Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1016/j.jgr.2018.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606819PMC
July 2019

Community-Delivered Heated Hatha Yoga as a Treatment for Depressive Symptoms: An Uncontrolled Pilot Study.

J Altern Complement Med 2019 Aug 10;25(8):814-823. Epub 2019 Jul 10.

1Depression Clinical and Research Program (DCRP), Department of Psychiatry, Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1089/acm.2018.0365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763961PMC
August 2019

Examining raphe-amygdala structural connectivity as a biological predictor of SSRI response.

J Affect Disord 2019 09 28;256:8-16. Epub 2019 May 28.

Department of Psychiatry, Stony Brook University, Stony Brook, NY, United States; Department of Psychiatry, Molecular Imaging and Neuropathology Division, Columbia University, New York, NY, United States.

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http://dx.doi.org/10.1016/j.jad.2019.05.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750958PMC
September 2019

Examining raphe-amygdala structural connectivity as a biological predictor of SSRI response.

J Affect Disord 2019 09 28;256:8-16. Epub 2019 May 28.

Department of Psychiatry, Stony Brook University, Stony Brook, NY, United States; Department of Psychiatry, Molecular Imaging and Neuropathology Division, Columbia University, New York, NY, United States.

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http://dx.doi.org/10.1016/j.jad.2019.05.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750958PMC
September 2019

Examining raphe-amygdala structural connectivity as a biological predictor of SSRI response.

J Affect Disord 2019 09 28;256:8-16. Epub 2019 May 28.

Department of Psychiatry, Stony Brook University, Stony Brook, NY, United States; Department of Psychiatry, Molecular Imaging and Neuropathology Division, Columbia University, New York, NY, United States.

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http://dx.doi.org/10.1016/j.jad.2019.05.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750958PMC
September 2019

Childhood trauma history is linked to abnormal brain connectivity in major depression.

Proc Natl Acad Sci U S A 2019 04 8;116(17):8582-8590. Epub 2019 Apr 8.

Center for Neuromodulation in Depression and Stress, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104;

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http://dx.doi.org/10.1073/pnas.1900801116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486762PMC
April 2019

A commentary on: statistical inference problems in sequential parallel comparison designs.

J Biopharm Stat 2019 22;29(6):1130-1133. Epub 2019 Feb 22.

Massachusetts General Hospital (MGH), Clinical Trials Network and Institute (CTNI), Boston, MA, USA.

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http://dx.doi.org/10.1080/10543406.2019.1584207DOI Listing
June 2020

Anxiety and anhedonia in depression: Associations with neuroticism and cognitive control.

J Affect Disord 2019 02 14;245:1070-1078. Epub 2018 Nov 14.

Department of Psychiatry, Center for Depression Research and Clinical Care, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9119, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2018.11.072DOI Listing
February 2019

Anxiety and anhedonia in depression: Associations with neuroticism and cognitive control.

J Affect Disord 2019 02 14;245:1070-1078. Epub 2018 Nov 14.

Department of Psychiatry, Center for Depression Research and Clinical Care, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9119, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2018.11.072DOI Listing
February 2019

Heart rate variability for treatment response between patients with major depressive disorder versus panic disorder: A 12-week follow-up study.

J Affect Disord 2019 03 18;246:157-165. Epub 2018 Dec 18.

Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, Korea; Department of Health Sciences & Technology, Department of Medical Device Management & Research, and Department of Clinical Research Design & Evaluation, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Seoul, Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2018.12.048DOI Listing
March 2019

Tachyphylaxis in major depressive disorder: A review of the current state of research.

J Affect Disord 2019 02 28;245:488-497. Epub 2018 Oct 28.

Clinical Trials Network and Institute, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01650327183168
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http://dx.doi.org/10.1016/j.jad.2018.10.357DOI Listing
February 2019

Can electronic health records revive central nervous system clinical trials?

Mol Psychiatry 2019 08;24(8):1096-1098

Center for Quantitative Health, Massachusetts General Hospital, Boston, MA, 02114, USA.

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http://www.nature.com/articles/s41380-018-0278-z
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http://dx.doi.org/10.1038/s41380-018-0278-zDOI Listing
August 2019

Can electronic health records revive central nervous system clinical trials?

Mol Psychiatry 2019 08;24(8):1096-1098

Center for Quantitative Health, Massachusetts General Hospital, Boston, MA, 02114, USA.

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http://www.nature.com/articles/s41380-018-0278-z
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http://dx.doi.org/10.1038/s41380-018-0278-zDOI Listing
August 2019

Increased adrenocorticotropic hormone (ACTH) levels predict severity of depression after six months of follow-up in outpatients with major depressive disorder.

Psychiatry Res 2018 12 21;270:246-252. Epub 2018 Sep 21.

Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; Department of Health Sciences & Technology, Department of Medical Device Management & Research, and Department of Clinical Research Design & Evaluation, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2018.09.047DOI Listing
December 2018

Mechanisms of Perceived Treatment Assignment and Subsequent Expectancy Effects in a Double Blind Placebo Controlled RCT of Major Depression.

Front Psychiatry 2018 7;9:424. Epub 2018 Sep 7.

Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.

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http://dx.doi.org/10.3389/fpsyt.2018.00424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137256PMC
September 2018

Effects of transcranial photobiomodulation with near-infrared light on sexual dysfunction.

Lasers Surg Med 2019 02 17;51(2):127-135. Epub 2018 Sep 17.

Department of Psychiatry, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York.

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http://dx.doi.org/10.1002/lsm.23011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382556PMC
February 2019

What is the overlap between subjective and objective cognitive impairments in MDD?

Ann Clin Psychiatry 2018 08;30(3):176-184

Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; E-MAIL:

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August 2018

Statistical harmonization corrects site effects in functional connectivity measurements from multi-site fMRI data.

Hum Brain Mapp 2018 11 1;39(11):4213-4227. Epub 2018 Jul 1.

Center for Neuromodulation in Depression and Stress, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/hbm.24241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179920PMC
November 2018

Patient primary language in a culturally focused intervention for Latino Americans with depression.

Ann Clin Psychiatry 2018 05;30(2):84-90

Depression Clinical and Research Program. Massachusetts General Hospital. 1 Bowdoin Square, 6th Floor, Boston, MA, 02114 USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223022PMC
May 2018

The promise and challenges of drug repurposing in psychiatry.

Authors:
Maurizio Fava

World Psychiatry 2018 Feb;17(1):28-29

Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.

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http://doi.wiley.com/10.1002/wps.20481
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http://dx.doi.org/10.1002/wps.20481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775121PMC
February 2018