Maurizio Fanciulli

Maurizio Fanciulli

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Maurizio Fanciulli

Maurizio Fanciulli

Publications by authors named "Maurizio Fanciulli"

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68Publications

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PTEN as a Prognostic/Predictive Biomarker in Cancer: An Unfulfilled Promise?

Cancers (Basel) 2019 Mar 28;11(4). Epub 2019 Mar 28.

Medical Oncology 1, IRCCS - Regina Elena National Cancer Institute, Rome 00144, Italy.

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http://dx.doi.org/10.3390/cancers11040435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520939PMC
March 2019

Reverse Engineering Cancer: Inferring Transcriptional Gene Signatures from Copy Number Aberrations with ICAro.

Cancers (Basel) 2019 Feb 22;11(2). Epub 2019 Feb 22.

SAFU Unit, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.

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http://dx.doi.org/10.3390/cancers11020256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406408PMC
February 2019

Recent advances in searching c-Myc transcriptional cofactors during tumorigenesis.

J Exp Clin Cancer Res 2018 Sep 27;37(1):239. Epub 2018 Sep 27.

Department of Pediatric Hematology/Oncology and of Cell and Gene Therapy, Bambino Gesù Children's Hospital, 00146, Rome, Italy.

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http://dx.doi.org/10.1186/s13046-018-0912-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161371PMC
September 2018

A new baby in the c-Myc-directed transcriptional machinery: Che-1/AATF.

Cell Cycle 2018 25;17(11):1286-1290. Epub 2018 Jul 25.

b SAFU, Department of Research , Advanced Diagnostics, and Technological Innovation, Translational Research Area, Regina Elena National Cancer Institute , Rome , Italy.

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http://dx.doi.org/10.1080/15384101.2018.1480227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110579PMC
July 2018

Che-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1α stabilization.

J Exp Clin Cancer Res 2017 02 18;36(1):32. Epub 2017 Feb 18.

UOSD SAFU, Department of Research, Diagnosis and Innovative Technologies, Translational Research Area, Regina Elena National Cancer Institute, Via E. Chianesi 53, 00144, Rome, Italy.

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http://dx.doi.org/10.1186/s13046-017-0497-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316229PMC
February 2017

Deptor: not only a mTOR inhibitor.

J Exp Clin Cancer Res 2017 01 13;36(1):12. Epub 2017 Jan 13.

SAFU, Department of Research, Advanced Diagnostics, and Technological Innovation, Translational Research Area, Regina Elena National Cancer Institute, 00144, Rome, Italy.

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http://dx.doi.org/10.1186/s13046-016-0484-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237168PMC
January 2017

Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells.

Oncotarget 2016 Oct;7(43):70546-70558

SAFU, Department of Research, Advanced Diagnostics, and Technological Innovation, Translational Research Area, Regina Elena National Cancer Institute, 00144, Rome, Italy.

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http://dx.doi.org/10.18632/oncotarget.12060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342573PMC
October 2016

Application of RNA-Seq Technology in Cancer Chemoprevention.

Methods Mol Biol 2016 ;1379:31-43

Laboratory of Epigenetic, Molecular Medicine Area, Italian National Cancer Institute "Regina Elena", 00144, Rome, Italy.

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http://dx.doi.org/10.1007/978-1-4939-3191-0_4DOI Listing
September 2016

eEF1Bγ binds the Che-1 and TP53 gene promoters and their transcripts.

J Exp Clin Cancer Res 2016 09 17;35(1):146. Epub 2016 Sep 17.

CNR-Institute of Molecular Biology and Pathology, Department of Molecular Medicine, Sapienza University, Viale Regina Elena 291, 00161, Rome, Italy.

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http://dx.doi.org/10.1186/s13046-016-0424-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027090PMC
September 2016

Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins.

Front Oncol 2016 15;6:34. Epub 2016 Feb 15.

SAFU Laboratory, Department of Research, Advanced Diagnostic, and Technological Innovation, Regina Elena Cancer Institute , Rome , Italy.

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http://dx.doi.org/10.3389/fonc.2016.00034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753824PMC
February 2016

AATF: A new actor in the complex world of mTOR.

Mol Cell Oncol 2016 Jan 15;3(1):e1040946. Epub 2015 Jul 15.

Epigenetics Laboratory, Molecular Medicine Area, Regina Elena National Cancer Institute ; Rome, Italy.

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http://dx.doi.org/10.1080/23723556.2015.1040946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845199PMC
January 2016

Discovering Che-1/AATF: a new attractive target for cancer therapy.

Front Genet 2015 10;6:141. Epub 2015 Apr 10.

Laboratory of Epigenetics, Molecular Medicine Area, Regina Elena National Cancer Institute, Rome Italy.

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http://dx.doi.org/10.3389/fgene.2015.00141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392318PMC
April 2015

VDR primary targets by genome-wide transcriptional profiling.

J Steroid Biochem Mol Biol 2014 Sep 13;143:348-56. Epub 2014 Apr 13.

Department of Oncology, McMaster University, Main Street West Hamilton, ON L8S 4K1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2014.03.007DOI Listing
September 2014

Electroporation as a strategy to promote HtrA1 gene uptake and chemotherapy efficacy in a mouse model of mesothelioma.

Front Biosci (Elite Ed) 2013 Jun 1;5:974-81. Epub 2013 Jun 1.

SAFU Department, Regina Elena Cancer Institute, Rome, Italy.

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June 2013

Electrochemotherapy for the treatment of recurring aponeurotic fibromatosis in a dog.

Can Vet J 2013 Jun;54(6):606-9

S.A.F.U. Department (Stabilimento Allevatore, Fornitore, Utilizzatore), Regina Elena Cancer Institute - Via delle Messi d' Oro 156, 00158 Rome, Italy (Spugnini, Fanciulli); Ambulatorio Veterinario Tor de Schiavi, Via Tor de Schiavi, 00194 Rome, Italy (Di Tosto, Salemme, Pecchia); Department of Environmental, Biological and Pharmaceutical Sciences and technologies, Second University of Naples, Italy (Baldi).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659460PMC
June 2013

Preclinical models in electrochemotherapy: the role of veterinary patients.

Future Oncol 2012 Jul;8(7):829-37

SAFU Department, Regina Elena Cancer Institute, Via delle Messi d'Oro 156, Rome 00158, Italy.

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http://dx.doi.org/10.2217/fon.12.64DOI Listing
July 2012

Poly(ADP-ribosyl)ation affects stabilization of Che-1 protein in response to DNA damage.

DNA Repair (Amst) 2011 Apr 12;10(4):380-9. Epub 2011 Feb 12.

Department of Cellular Biotechnologies and Haematology, Section of Clinical Biochemistry, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.dnarep.2011.01.002DOI Listing
April 2011

Role of senataxin in DNA damage and telomeric stability.

DNA Repair (Amst) 2011 Feb 26;10(2):199-209. Epub 2010 Nov 26.

II School of Medicine, Department of Clinical and Molecular Medicine, University La Sapienza, Roma, Italy. andrea.deamicis@unirom

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http://dx.doi.org/10.1016/j.dnarep.2010.10.012DOI Listing
February 2011

hSirT1-dependent regulation of the PCAF-E2F1-p73 apoptotic pathway in response to DNA damage.

Mol Cell Biol 2009 Apr 2;29(8):1989-98. Epub 2009 Feb 2.

Laboratory of Gene Expression, Fondazione A Cesalpino, Viale del Policlinico 155, 00161 Rome, Italy.

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http://dx.doi.org/10.1128/MCB.00552-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663319PMC
April 2009

Novel activation domain derived from Che-1 cofactor coupled with the artificial protein Jazz drives utrophin upregulation.

Neuromuscul Disord 2009 Feb 21;19(2):158-62. Epub 2009 Jan 21.

Istituto di Biologia e Patologia Molecolari, CNR, c/o Regina Elena Cancer Institute, Via delle Messi d'Oro 156, 00158 Rome, Italy.

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http://dx.doi.org/10.1016/j.nmd.2008.11.005DOI Listing
February 2009

Che-1/AATF, a multivalent adaptor connecting transcriptional regulation, checkpoint control, and apoptosis.

Biochem Cell Biol 2007 Aug;85(4):477-83

Istituto di Biologia e Patologia Molecolare, CNR, 00158 Rome, Italy.

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http://dx.doi.org/10.1139/O07-062DOI Listing
August 2007

The prolyl isomerase Pin1 affects Che-1 stability in response to apoptotic DNA damage.

J Biol Chem 2007 Jul 27;282(27):19685-91. Epub 2007 Apr 27.

Laboratory B, Experimental Research Center and Rome Oncogenomic Center, Regina Elena Cancer Institute, Via delle Messi d'Oro 156, 00158 Rome, Italy.

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http://dx.doi.org/10.1074/jbc.M610282200DOI Listing
July 2007

The anti-apoptotic factor Che-1/AATF links transcriptional regulation, cell cycle control, and DNA damage response.

Cell Div 2007 Jul 16;2:21. Epub 2007 Jul 16.

Instituto di Biologia e Patologia Molecolare, CNR, c/o Regina Elena Cancer Institute, Via Delle Messi d'oro 156, 00158 Rome, Italy.

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http://celldiv.biomedcentral.com/articles/10.1186/1747-1028-
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http://dx.doi.org/10.1186/1747-1028-2-21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1948887PMC
July 2007

NRAGE associates with the anti-apoptotic factor Che-1 and regulates its degradation to induce cell death.

J Cell Sci 2007 Jun 8;120(Pt 11):1852-8. Epub 2007 May 8.

Department of Experimental Medicine, Via Vetoio, Coppito 2, University of L'Aquila, 67100 L'Aquila, Italy.

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http://dx.doi.org/10.1242/jcs.03454DOI Listing
June 2007

The artificial 4-zinc-finger protein Bagly binds human utrophin promoter A at the endogenous chromosomal site and activates transcription.

Biochem Cell Biol 2007 Jun;85(3):358-65

Istituto di Biologia e Patologia Molecolari, CNR, c/o Regina Elena Cancer Institute, Via delle Messi d'Oro 156, 00158 Rome, Italy.

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http://dx.doi.org/10.1139/o07-015DOI Listing
June 2007

Che-1: a new effector of checkpoints signaling.

Cell Cycle 2007 Apr 22;6(7):804-6. Epub 2007 Apr 22.

Department of Experimental Medicine, Via Vetoio Coppito 2, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.4161/cc.6.7.4043DOI Listing
April 2007

c-Myc phosphorylation is required for cellular response to oxidative stress.

Mol Cell 2006 Feb;21(4):509-19

Experimental Chemotherapy Laboratory, Experimental Research Center, Regina Elena Cancer Institute, Rome, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S109727650600010
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http://dx.doi.org/10.1016/j.molcel.2006.01.009DOI Listing
February 2006

RNA polymerase II subunit 3 is retained in the cytoplasm by its interaction with HCR, the psoriasis vulgaris candidate gene product.

J Cell Sci 2005 Sep 1;118(Pt 18):4253-60. Epub 2005 Sep 1.

Istituto di Biologia e Patologia Molecolari CNR, Universita' di Roma La Sapienza, P. le A. Moro, 5, 00185 Roma, Italy.

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http://dx.doi.org/10.1242/jcs.02545DOI Listing
September 2005

bcl-2 induction of urokinase plasminogen activator receptor expression in human cancer cells through Sp1 activation: involvement of ERK1/ERK2 activity.

J Biol Chem 2004 Feb 1;279(8):6737-45. Epub 2003 Dec 1.

Experimental Chemotherapy Laboratory, Regina Elena Cancer Institute, Via delle Messi d'Oro 156, 00158 Rome, Italy.

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http://dx.doi.org/10.1074/jbc.M308938200DOI Listing
February 2004

Genomic structure and transcriptional regulation of Che-1, a novel partner of Rb.

Gene 2003 Dec;321:57-63

Istituto Pasteur Fondazione Cenci-Bolognetti, Department of Human Physiology and Pharmacology, University La Sapienza, Rome, Italy.

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http://dx.doi.org/10.1016/s0378-1119(03)00834-5DOI Listing
December 2003

Functional interaction of the subunit 3 of RNA polymerase II (RPB3) with transcription factor-4 (ATF4).

FEBS Lett 2003 Jul;547(1-3):15-9

Laboratory B, Regina Elena Cancer Institute, Via delle Messi d'Oro 156, 00158, Rome, Italy.

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http://dx.doi.org/10.1016/s0014-5793(03)00659-8DOI Listing
July 2003