Maura Sonego

HSP90 identified by a proteomic approach as druggable target to reverse platinum resistance in ovarian cancer.

Authors:

Rita Lombardi Maura Sonego Biagio Pucci Laura Addi Federica Iannelli Francesca Capone Luigi Alfano Maria Serena Roca Maria Rita Milone Tania Moccia Alice Costa Elena Di Gennaro Francesca Bruzzese Gustavo Baldassarre Alfredo Budillon

Mol Oncol 2020 Dec 16. Epub 2020 Dec 16.

Experimental Pharmacology Unit-Laboratories of Naples and Mercogliano (AV), Istituto Nazionale per lo Studio e la Cura dei Tumori "Fondazione G. Pascale" - IRCCS, Naples, Italy.

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December 2020

CDKN1B mutation and copy number variation are associated with tumor aggressiveness in luminal breast cancer.

J Pathol 2020 Nov 3. Epub 2020 Nov 3.

Molecular Oncology Unit, Centro di Riferimento Oncologico di Aviano (CRO Aviano), IRCCS, National Cancer Institute, Aviano, Italy.

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November 2020

Serum- and glucocorticoid- inducible kinase 2, SGK2, is a novel autophagy regulator and modulates platinum drugs response in cancer cells.

Authors:

Valentina Ranzuglia Ilaria Lorenzon Ilenia Pellarin Maura Sonego Alessandra Dall'Acqua Sara D'Andrea Sara Lovisa Ilenia Segatto Michela Coan Jerry Polesel Diego Serraino Patrizia Sabatelli Paola Spessotto Barbara Belletti Gustavo Baldassarre Monica Schiappacassi

Oncogene 2020 10 27;39(40):6370-6386. Epub 2020 Aug 27.

Division of Molecular Oncology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, 33081, Aviano, Italy.

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October 2020

A new role for IDH1 in the control of ovarian cancer cells metabolism and senescence.

Authors:

Maura Sonego Gustavo Baldassarre

Ann Transl Med 2020 Jun;8(12):780

Division of Molecular Oncology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, National Cancer Institute, Aviano, Italy.

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June 2020

Splicing factor proline- and glutamine-rich (SFPQ) protein regulates platinum response in ovarian cancer-modulating SRSF2 activity.

Authors:

Ilenia Pellarin Alessandra Dall'Acqua Alice Gambelli Ilenia Pellizzari Sara D'Andrea Maura Sonego Ilaria Lorenzon Monica Schiappacassi Barbara Belletti Gustavo Baldassarre

Oncogene 2020 05 24;39(22):4390-4403. Epub 2020 Apr 24.

Division of Molecular Oncology, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, National Cancer Institute, 33081, Aviano, PN, Italy.

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May 2020

Identification and Characterization of a New Platinum-Induced TP53 Mutation in MDAH Ovarian Cancer Cells.

Authors:

Ilaria Lorenzon Ilenia Pellarin Ilenia Pellizzari Sara D'Andrea Barbara Belletti Maura Sonego Gustavo Baldassarre Monica Schiappacassi

Cells 2019 12 21;9(1). Epub 2019 Dec 21.

Division of Molecular Oncology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, National Cancer Institute, Via Franco Gallini 2, 33081 Aviano, Italy.

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December 2019

TIMP-1 is Overexpressed and Secreted by Platinum Resistant Epithelial Ovarian Cancer Cells.

Authors:

Maura Sonego Evelina Poletto Eliana Pivetta Milena S Nicoloso Rosanna Pellicani Gian Luca Rampioni Vinciguerra Francesca Citron Roberto Sorio Maurizio Mongiat Gustavo Baldassarre

Cells 2019 12 18;9(1). Epub 2019 Dec 18.

Division of Molecular Oncology, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, 33081 Aviano, Italy.

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December 2019

USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability.

Authors:

Maura Sonego Ilenia Pellarin Alice Costa Gian Luca Rampioni Vinciguerra Michela Coan Alexandra Kraut Sara D'Andrea Alessandra Dall'Acqua Dan Cacsire Castillo-Tong Daniela Califano Simona Losito Riccardo Spizzo Yohann Couté Andrea Vecchione Barbara Belletti Monica Schiappacassi Gustavo Baldassarre

Sci Adv 2019 05 8;5(5):eaav3235. Epub 2019 May 8.

Division of Molecular Oncology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, National Cancer Institute, 33081 Aviano, Italy.

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May 2019

CDK6 protects epithelial ovarian cancer from platinum-induced death via FOXO3 regulation.

Authors:

Alessandra Dall'Acqua Maura Sonego Ilenia Pellizzari Ilenia Pellarin Vincenzo Canzonieri Sara D'Andrea Sara Benevol Roberto Sorio Giorgio Giorda Daniela Califano Marina Bagnoli Loredana Militello Delia Mezzanzanica Gennaro Chiappetta Joshua Armenia Barbara Belletti Monica Schiappacassi Gustavo Baldassarre

EMBO Mol Med 2017 10;9(10):1415-1433

Division of Molecular Oncology, CRO Aviano, IRCCS, National Cancer Institute, Aviano, Italy

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October 2017

Common biological phenotypes characterize the acquisition of platinum-resistance in epithelial ovarian cancer cells.

Authors:

Maura Sonego Ilenia Pellizzari Alessandra Dall'Acqua Eliana Pivetta Ilaria Lorenzon Sara Benevol Riccardo Bomben Paola Spessotto Roberto Sorio Valter Gattei Barbara Belletti Monica Schiappacassi Gustavo Baldassarre

Sci Rep 2017 08 2;7(1):7104. Epub 2017 Aug 2.

Division of Molecular Oncology, National Cancer Institute, 33081, Aviano, Italy.

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August 2017

Biomarker analysis of the MITO2 phase III trial of first-line treatment in ovarian cancer: predictive value of DNA-PK and phosphorylated ACC.

Oncotarget 2016 11;7(45):72654-72661

Istituto Nazionale per lo Studio e la Cura dei Tumori - Fondazione G.Pascale, IRCCS, Napoli, Italy.

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November 2016

SUMOylation regulates p27Kip1 stability and localization in response to TGFβ.

Authors:

Sara Lovisa Simona Citro Maura Sonego Alessandra Dall'Acqua Valentina Ranzuglia Stefania Berton Alfonso Colombatti Barbara Belletti Susanna Chiocca Monica Schiappacassi Gustavo Baldassarre

J Mol Cell Biol 2016 Feb 8;8(1):17-30. Epub 2015 Oct 8.

Division of Experimental Oncology 2 Centro di Riferimento Oncologico, National Cancer Institute, Aviano 33081, Italy

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February 2016

Surgery-induced wound response promotes stem-like and tumor-initiating features of breast cancer cells, via STAT3 signaling.

Authors:

Ilenia Segatto Stefania Berton Maura Sonego Samuele Massarut Tiziana Perin Erica Piccoli Alfonso Colombatti Andrea Vecchione Gustavo Baldassarre Barbara Belletti

Oncotarget 2014 Aug;5(15):6267-79

Division of Experimental Oncology 2, CRO, National Cancer Institute, Aviano 33081, Italy.

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August 2014

p70S6 kinase mediates breast cancer cell survival in response to surgical wound fluid stimulation.

Authors:

Ilenia Segatto Stefania Berton Maura Sonego Samuele Massarut Linda Fabris Joshua Armenia Mario Mileto Alfonso Colombatti Andrea Vecchione Gustavo Baldassarre Barbara Belletti

Mol Oncol 2014 May 12;8(3):766-80. Epub 2014 Mar 12.

Division of Experimental Oncology 2, CRO, National Cancer Institute, Aviano 33081, Italy. Electronic address:

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May 2014

Inhibition of breast cancer local relapse by targeting p70S6 kinase activity.

Authors:

Ilenia Segatto Stefania Berton Maura Sonego Samuele Massarut Sara D'Andrea Tiziana Perin Linda Fabris Joshua Armenia Gianluca Rampioni Sara Lovisa Monica Schiappacassi Alfonso Colombatti Robert G Bristow Andrea Vecchione Gustavo Baldassarre Barbara Belletti

J Mol Cell Biol 2013 Dec 29;5(6):428-31. Epub 2013 Jul 29.

Division of Experimental Oncology 2, CRO, National Cancer Institute, Aviano 33081, Italy.

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December 2013

A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis.

Proc Natl Acad Sci U S A 2013 Jun 22;110(24):9845-50. Epub 2013 May 22.

Division of Pathology and Medical Oncology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, University Sapienza, Santo Andrea Hospital, 00100 Rome, Italy.

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June 2013