Publications by authors named "Matthias Wilmanns"

100Publications

The crystal structure of mycobacterial epoxide hydrolase A.

Sci Rep 2020 Oct 6;10(1):16539. Epub 2020 Oct 6.

European Molecular Biology Laboratory, Hamburg Unit, Notkestrasse 85, 22603, Hamburg, Germany.

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http://dx.doi.org/10.1038/s41598-020-73452-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538969PMC
October 2020

The pMy vector series: A versatile cloning platform for the recombinant production of mycobacterial proteins in Mycobacterium smegmatis.

Protein Sci 2020 Oct 2. Epub 2020 Oct 2.

Hamburg Unit, European Molecular Biology Laboratory, Hamburg, Germany.

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http://dx.doi.org/10.1002/pro.3962DOI Listing
October 2020

Uncovering targeting priority to yeast peroxisomes using an in-cell competition assay.

Proc Natl Acad Sci U S A 2020 09 17;117(35):21432-21440. Epub 2020 Aug 17.

Department of Molecular Genetics, Weizmann Institute of Science, 7610001 Rehovot, Israel;

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http://dx.doi.org/10.1073/pnas.1920078117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474679PMC
September 2020

Structure-Based Identification and Functional Characterization of a Lipocalin in the Malaria Parasite Plasmodium falciparum.

Cell Rep 2020 Jun;31(12):107817

Centre for Structural Systems Biology, 22607 Hamburg, Germany; Bernhard Nocht Institute for Tropical Medicine, 20359 Hamburg, Germany; University of Hamburg, 20146 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107817DOI Listing
June 2020

H, C, and N backbone assignments of the C-terminal region of the human retinoic acid-induced protein 2.

Biomol NMR Assign 2020 Oct 18;14(2):271-275. Epub 2020 Jun 18.

Leibniz Institute on Aging - Fritz Lipmann Institute, Beutenbergstr. 11, 07745, Jena, Germany.

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http://dx.doi.org/10.1007/s12104-020-09960-9DOI Listing
October 2020

Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake.

Nat Commun 2020 01 23;11(1):440. Epub 2020 Jan 23.

European Molecular Biology Laboratory (EMBL), Structural and Computational Biology Unit, Meyerhofstraße 1, 69117, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41467-020-14343-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978347PMC
January 2020

The ATPases of the mycobacterial type VII secretion system: Structural and mechanistic insights into secretion.

Prog Biophys Mol Biol 2020 05 22;152:25-34. Epub 2019 Nov 22.

European Molecular Biology Laboratory, Hamburg Unit, Notkestrasse 85, 22607, Hamburg, Germany; University Hamburg Clinical Centre Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.pbiomolbio.2019.11.008DOI Listing
May 2020

Subcellular localization and stability of MITF are modulated by the bHLH-Zip domain.

Pigment Cell Melanoma Res 2019 01 20;32(1):41-54. Epub 2018 Jul 20.

Faculty of Medicine, Department of Biochemistry and Molecular Biology, BioMedical Center, University of Iceland, Reykjavik, Iceland.

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http://dx.doi.org/10.1111/pcmr.12721DOI Listing
January 2019

Model-based local density sharpening of cryo-EM maps.

Elife 2017 10 23;6. Epub 2017 Oct 23.

Structural and Computational Biology, European Molecular Biology Laboratory, Heidelberg, Germany.

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https://elifesciences.org/articles/27131
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http://dx.doi.org/10.7554/eLife.27131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679758PMC
October 2017

Crystallographic insights into a cobalt (III) sepulchrate based alternative cofactor system of P450 BM3 monooxygenase.

Biochim Biophys Acta Proteins Proteom 2018 Jan 22;1866(1):134-140. Epub 2017 Jul 22.

Lehrstuhl für Biotechnologie, RWTH Aachen University, Worringerweg 3, 52074 Aachen, Germany; DWI-Leibniz Institut für Interaktive Materialien, Forckenbeckstraße 50, 52056 Aachen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbapap.2017.07.010DOI Listing
January 2018

Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli.

Data Brief 2016 Sep 29;8:733-40. Epub 2016 Jun 29.

Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, Forskningsparken, University of Oslo and Oslo University Hospitals, 0349 Oslo, Norway; Institute for Experimental Medical Research, Oslo University Hospital, Norway.

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http://dx.doi.org/10.1016/j.dib.2016.06.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950174PMC
September 2016

A standardized production pipeline for high profile targets from Mycobacterium tuberculosis.

Proteomics Clin Appl 2016 10 3;10(9-10):1049-1057. Epub 2016 Aug 3.

European Molecular Biology Laboratory (EMBL), Hamburg Unit, Hamburg, Germany.

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http://dx.doi.org/10.1002/prca.201600033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095800PMC
October 2016

Using the fluorescent properties of STO-609 as a tool to assist structure-function analyses of recombinant CaMKK2.

Biochem Biophys Res Commun 2016 07 11;476(2):102-7. Epub 2016 May 11.

Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, Forskningsparken, University of Oslo, Oslo University Hospitals, 0349 Oslo, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.05.045DOI Listing
July 2016

Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites.

Structure 2016 06 28;24(6):851-61. Epub 2016 Apr 28.

European Molecular Biology Laboratory, Hamburg Unit, Notkestrasse 85, 22607 Hamburg, Germany; University of Hamburg Clinical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.str.2016.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906247PMC
June 2016

In cellulo serial crystallography of alcohol oxidase crystals inside yeast cells.

IUCrJ 2016 Mar 12;3(Pt 2):88-95. Epub 2016 Jan 12.

Hamburg Unit c/o DESY, European Molecular Biology Laboratory (EMBL), Notkestrasse 85, 22607 Hamburg, Germany; University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1107/S2052252515022927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775156PMC
March 2016

Structural biology of the import pathways of peroxisomal matrix proteins.

Biochim Biophys Acta 2016 May 9;1863(5):804-13. Epub 2015 Oct 9.

Institute of Structural Biology, Helmholtz Zentrum München, 85764 Neuherberg, Germany; Center for Integrated Protein Science Munich (CIPSM) at Department of Chemistry, Technische Universität München, Lichtenbergstr.4, 85747 Garching, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2015.09.034DOI Listing
May 2016

Towards the molecular mechanism of the integration of peroxisomal membrane proteins.

Biochim Biophys Acta 2016 May 3;1863(5):863-9. Epub 2015 Oct 3.

EMBL Hamburg, c/o DESY, Building 25A, Notkestraße 85, 22603 Hamburg, Germany; University of Hamburg Clinical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2015.09.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819957PMC
May 2016

Structural insights into cargo recognition by the yeast PTS1 receptor.

J Biol Chem 2015 Oct 10;290(44):26610-26. Epub 2015 Sep 10.

From the Institute of Biochemistry and Pathobiochemistry, Faculty of Medicine, System Biochemistry, Ruhr-University Bochum, D-44780 Bochum, Germany,

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http://dx.doi.org/10.1074/jbc.M115.657973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646318PMC
October 2015

Molecular mechanisms of protein kinase regulation by calcium/calmodulin.

Bioorg Med Chem 2015 Jun 24;23(12):2749-60. Epub 2015 Apr 24.

EMBL Hamburg, c/o DESY, Building 25A, Notkestraße 85, 22603 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2015.04.051DOI Listing
June 2015

Refined requirements for protein regions important for activity of the TALE AvrBs3.

PLoS One 2015 17;10(3):e0120214. Epub 2015 Mar 17.

Institute for Biology, Department of Genetics, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120214PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363659PMC
December 2015

Crystal structure of the VapBC-15 complex from Mycobacterium tuberculosis reveals a two-metal ion dependent PIN-domain ribonuclease and a variable mode of toxin-antitoxin assembly.

J Struct Biol 2014 Dec 22;188(3):249-58. Epub 2014 Oct 22.

Department of Biophysics, All India Institute of Medical Sciences, New Delhi, India. Electronic address:

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http://dx.doi.org/10.1016/j.jsb.2014.10.002DOI Listing
December 2014

Ligand-induced compaction of the PEX5 receptor-binding cavity impacts protein import efficiency into peroxisomes.

Traffic 2015 Jan 2;16(1):85-98. Epub 2014 Dec 2.

Hamburg Unit, European Molecular Biology Laboratory Hamburg Unit, Hamburg, Germany.

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http://dx.doi.org/10.1111/tra.12238DOI Listing
January 2015

Structure of the Mycobacterium tuberculosis type VII secretion system chaperone EspG5 in complex with PE25-PPE41 dimer.

Mol Microbiol 2014 Oct 15;94(2):367-82. Epub 2014 Sep 15.

Department of Molecular & Cellular Biochemistry, University of Kentucky, Lexington, KY, 40536, USA; Center for Structural Biology, University of Kentucky, Lexington, KY, 40536, USA.

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http://doi.wiley.com/10.1111/mmi.12770
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http://dx.doi.org/10.1111/mmi.12770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192059PMC
October 2014

Induction of insulin-like growth factor 1 splice forms by subfragments of myofibrillar proteins.

Mol Cell Endocrinol 2015 Jan 22;399:69-77. Epub 2014 Aug 22.

Bach Institute of Biochemistry, Russian Academy of Sciences, Leninskiy Prospect 33, 119071 Moscow, Russia; Kurchatov NBIC Centre, Russian National Research Centre "Kurchatov Institute", Akademika Kurchatova sq. 1, 123182 Moscow, Russia. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2014.08.010DOI Listing
January 2015

Active site conformational changes upon reaction intermediate biotinyl-5'-AMP binding in biotin protein ligase from Mycobacterium tuberculosis.

Protein Sci 2014 Jul 22;23(7):932-9. Epub 2014 Apr 22.

European Molecular Biology Laboratory, EMBL-Hamburg, c/o DESY, Building 25A, Notkestrasse 85, 22603, Hamburg, Germany.

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http://dx.doi.org/10.1002/pro.2475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4088977PMC
July 2014

Design of a bZip transcription factor with homo/heterodimer-induced DNA-binding preference.

Structure 2014 Mar 13;22(3):466-77. Epub 2014 Feb 13.

EMBL Hamburg c/o DESY, Notkestraße 85, 22603 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.str.2013.12.017DOI Listing
March 2014

A PEF/Y substrate recognition and signature motif plays a critical role in DAPK-related kinase activity.

Chem Biol 2014 Feb 16;21(2):264-73. Epub 2014 Jan 16.

European Molecular Biology Laboratory Hamburg, Notkestrasse 85, 22603 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2013.12.008DOI Listing
February 2014

Development of accessible peptidic tool compounds to study the phosphatase PTP1B in intact cells.

ACS Chem Biol 2014 Mar 15;9(3):769-76. Epub 2014 Jan 15.

Genome Biology Unit, European Molecular Biology Laboratory , Heidelberg, Germany.

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http://dx.doi.org/10.1021/cb400903uDOI Listing
March 2014

The 11th International Conference on Biology and Synchrotron Radiation.

J Synchrotron Radiat 2014 Jan 3;21(Pt 1):280-2. Epub 2013 Dec 3.

European Molecular Biology Laboratory, Notkestrasse 85, D-22603 Hamburg, Germany.

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http://dx.doi.org/10.1107/S1600577513030609DOI Listing
January 2014

Group III alcohol dehydrogenase from Pectobacterium atrosepticum: insights into enzymatic activity and organization of the metal ion-containing region.

Appl Microbiol Biotechnol 2014 May 22;98(9):4041-51. Epub 2013 Nov 22.

Institute of Technical Microbiology, Hamburg University of Technology (TUHH), Kasernenstr. 12, 21073, Hamburg, Germany.

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http://dx.doi.org/10.1007/s00253-013-5374-zDOI Listing
May 2014

Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling.

Mol Biol Cell 2013 Oct 28;24(20):3215-26. Epub 2013 Aug 28.

Institute for Cell Biology, University of Bonn, D-53121 Bonn, Germany European Molecular Biology Laboratory-Hamburg/Deutsches Elektronen-Synchrotron, D-22603 Hamburg, Germany Department of Medicinal Immunology, Charité-University Medicine Berlin, D-13353 Berlin, Germany Department of Neurology, Neuromuscular Center Ruhrgebiet, University Hospital Bergmannsheil, Ruhr-University Bochum, D-44789 Bochum, Germany.

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http://dx.doi.org/10.1091/mbc.E13-04-0202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810769PMC
October 2013

Catalytic mechanism of α-phosphate attack in dUTPase is revealed by X-ray crystallographic snapshots of distinct intermediates, 31P-NMR spectroscopy and reaction path modelling.

Nucleic Acids Res 2013 Dec 27;41(22):10542-55. Epub 2013 Aug 27.

Laboratory of Genome Metabolism, Institute of Enzymology, Research Center for Natural Sciences, Hungarian Academy of Sciences, Budapest H-1113, Hungary, Laboratory of Molecular Biology, NIDDK, NIH, Bethesda, MD 20892, USA, Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg D-69117, Germany, Laboratory of Structural Chemistry and Biology, Institute of Chemistry, Eötvös Loránd University, Budapest H-1117, Hungary, Protein Modelling Group MTA-ELTE, Institute of Chemistry, Eötvös Loránd University, Budapest H-1117, Hungary, Department of Chemistry, King's College London, London, SE1 1UL, UK, Department of Medical Chemistry, University of Szeged, Hungary, Department of Computer Science, Eötvös Loránd University, Budapest, Hungary, European Molecular Biology Laboratory, Hamburg Outstation, Hamburg D-22603, Germany and Department of Applied Biotechnology and Food Sciences, Budapest University of Technology and Economics, Budapest, Hungary.

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http://dx.doi.org/10.1093/nar/gkt756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905902PMC
December 2013

Structural and biochemical characterization of Rv2140c, a phosphatidylethanolamine-binding protein from Mycobacterium tuberculosis.

FEBS Lett 2013 Sep 29;587(18):2936-42. Epub 2013 Jul 29.

EMBL c/o DESY, Notkestrasse 85, 22603 Hamburg, Germany.

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http://dx.doi.org/10.1016/j.febslet.2013.07.038DOI Listing
September 2013

A disulphide bond in the E2 enzyme Pex4p modulates ubiquitin-conjugating activity.

Sci Rep 2013 ;3:2212

European Molecular Biology Laboratory, Structural Biology Unit, Notkestrasse 85, 22603, Hamburg, Germany.

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http://dx.doi.org/10.1038/srep02212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505396PMC
February 2014

MITF mutations associated with pigment deficiency syndromes and melanoma have different effects on protein function.

Hum Mol Genet 2013 Nov 20;22(21):4357-67. Epub 2013 Jun 20.

Department of Biochemistry and Molecular Biology, BioMedical Center, Faculty of Medicine, University of Iceland, Vatnsmyrarvegi 16, 101 Reykjavik, Iceland.

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http://dx.doi.org/10.1093/hmg/ddt285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888191PMC
November 2013

Structural and functional diversity in the activity and regulation of DAPK-related protein kinases.

FEBS J 2013 Nov 5;280(21):5533-50. Epub 2013 Jul 5.

European Molecular Biology Laboratory, Hamburg, Germany.

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http://dx.doi.org/10.1111/febs.12384DOI Listing
November 2013

Elucidating human phosphatase-substrate networks.

Sci Signal 2013 May 14;6(275):rs10. Epub 2013 May 14.

Genome Biology Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1126/scisignal.2003203DOI Listing
May 2013

P450 BM3 crystal structures reveal the role of the charged surface residue Lys/Arg184 in inversion of enantioselective styrene epoxidation.

Chem Commun (Camb) 2013 May 15;49(41):4694-6. Epub 2013 Apr 15.

Lehrstuhl für Biotechnologie, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.

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http://dx.doi.org/10.1039/c3cc39076dDOI Listing
May 2013

Structural and biochemical characterisation of a NAD⁺-dependent alcohol dehydrogenase from Oenococcus oeni as a new model molecule for industrial biotechnology applications.

Appl Microbiol Biotechnol 2013 Oct 6;97(20):8963-75. Epub 2013 Feb 6.

Institute of Technical Microbiology, Hamburg University of Technology (TUHH), Kasernenstr. 12, 21073, Hamburg, Germany.

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http://dx.doi.org/10.1007/s00253-013-4725-0DOI Listing
October 2013

A unique Oct4 interface is crucial for reprogramming to pluripotency.

Nat Cell Biol 2013 Mar 3;15(3):295-301. Epub 2013 Feb 3.

Department for Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Röntgenstrasse 20, Münster D-48149, Germany.

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http://dx.doi.org/10.1038/ncb2680DOI Listing
March 2013

Catalysis uncoupling in a glutamine amidotransferase bienzyme by unblocking the glutaminase active site.

Chem Biol 2012 Dec;19(12):1589-99

EMBL Hamburg, Notkestrasse 85, Building 25A, D-22603 Hamburg, Germany.

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http://dx.doi.org/10.1016/j.chembiol.2012.10.012DOI Listing
December 2012

Structural characterization of a D-isomer specific 2-hydroxyacid dehydrogenase from Lactobacillus delbrueckii ssp. bulgaricus.

J Struct Biol 2013 Feb 27;181(2):179-84. Epub 2012 Oct 27.

EMBL c/o DESY, Notkestrasse 85, D-22603 Hamburg, Germany.

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http://dx.doi.org/10.1016/j.jsb.2012.10.009DOI Listing
February 2013

The role of active-site Phe87 in modulating the organic co-solvent tolerance of cytochrome P450 BM3 monooxygenase.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 Sep 29;68(Pt 9):1013-7. Epub 2012 Aug 29.

Rudolf Virchow Centre for Biomedical Research, Josef Schneider Strasse 2, 97070 Würzburg, Germany.

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http://dx.doi.org/10.1107/S1744309112031570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433188PMC
September 2012

Insights into ubiquitin-conjugating enzyme/ co-activator interactions from the structure of the Pex4p:Pex22p complex.

EMBO J 2012 Jan 15;31(2):391-402. Epub 2011 Nov 15.

Structural Biology Unit, European Molecular Biology Laboratory, Hamburg, Germany.

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http://dx.doi.org/10.1038/emboj.2011.411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261564PMC
January 2012

Fast-folding alpha-helices as reversible strain absorbers in the muscle protein myomesin.

Proc Natl Acad Sci U S A 2011 Aug 8;108(34):14139-44. Epub 2011 Aug 8.

Physik Department E22, Technische Universität München, James-Franck-Straße, 85748 Garching, Germany.

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http://dx.doi.org/10.1073/pnas.1105734108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161521PMC
August 2011

Structural features of peroxisomal catalase from the yeast Hansenula polymorpha.

Acta Crystallogr D Biol Crystallogr 2011 Aug 12;67(Pt 8):690-8. Epub 2011 Jul 12.

Department of Structural and Quantitative Biology, Centro de Investigaciones Biológicas (CIB-CSIC), Ramiro de Maetzu, 28040 Madrid, Spain.

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http://scripts.iucr.org/cgi-bin/paper?S0907444911022463
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http://dx.doi.org/10.1107/S0907444911022463DOI Listing
August 2011

The progress made in determining the Mycobacterium tuberculosis structural proteome.

Proteomics 2011 Aug 14;11(15):3128-33. Epub 2011 Jun 14.

European Molecular Biology Laboratory - Hamburg, c/o DESY, Hamburg, Germany.

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http://dx.doi.org/10.1002/pmic.201000787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345573PMC
August 2011

Related (βα)8-barrel proteins in histidine and tryptophan biosynthesis: a paradigm to study enzyme evolution.

Chembiochem 2011 Jul 8;12(10):1487-94. Epub 2011 Jun 8.

European Molecular Biology Laboratory, Hamburg Unit, Hamburg, Germany.

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http://dx.doi.org/10.1002/cbic.201100082DOI Listing
July 2011

Rapid development of genetically encoded FRET reporters.

ACS Chem Biol 2011 Jul 28;6(7):685-91. Epub 2011 Apr 28.

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http://dx.doi.org/10.1021/cb100402nDOI Listing
July 2011

Improved mycobacterial protein production using a Mycobacterium smegmatis groEL1ΔC expression strain.

BMC Biotechnol 2011 Mar 25;11:27. Epub 2011 Mar 25.

European Molecular Biology Laboratory (EMBL), Hamburg Outstation, c/o DESY, Building 25a, Notkestrasse 85, 22603 Hamburg, Germany.

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http://dx.doi.org/10.1186/1472-6750-11-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076238PMC
March 2011

Expression of protein complexes using multiple Escherichia coli protein co-expression systems: a benchmarking study.

J Struct Biol 2011 Aug 5;175(2):159-70. Epub 2011 Mar 5.

Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Institut National de Santé et de Recherche Médicale (Inserm), U964/Centre National deRecherche Scientifique (CNRS), UMR 7104, Université de Strasbourg, 1 Rue Laurent Fries, 67404 Illkirch, France.

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http://linkinghub.elsevier.com/retrieve/pii/S104784771100051
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http://dx.doi.org/10.1016/j.jsb.2011.03.004DOI Listing
August 2011

Bisubstrate specificity in histidine/tryptophan biosynthesis isomerase from Mycobacterium tuberculosis by active site metamorphosis.

Proc Natl Acad Sci U S A 2011 Mar 14;108(9):3554-9. Epub 2011 Feb 14.

European Molecular Biology Laboratory, Hamburg Unit, Notkestrasse 85, D-22603 Hamburg, Germany.

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http://dx.doi.org/10.1073/pnas.1015996108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048130PMC
March 2011

Structural synthetic biotechnology: from molecular structure to predictable design for industrial strain development.

Trends Biotechnol 2010 Oct 19;28(10):534-42. Epub 2010 Aug 19.

Institute of Bioprocess and Biosystems Engineering, Hamburg University of Technology, Denickestrasse 15, D-21073 Hamburg, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S016777991000120
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http://dx.doi.org/10.1016/j.tibtech.2010.07.004DOI Listing
October 2010

Highlight: of systems and structures.

Biol Chem 2010 Jul;391(7):717-8

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http://dx.doi.org/10.1515/BC.2010.095DOI Listing
July 2010

Molecular basis of the head-to-tail assembly of giant muscle proteins obscurin-like 1 and titin.

EMBO Rep 2010 Jul 21;11(7):534-40. Epub 2010 May 21.

EMBL-Hamburg, Notkestrasse 85, Hamburg D-22603, Germany.

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http://dx.doi.org/10.1038/embor.2010.65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897112PMC
July 2010

Molecular basis of the death-associated protein kinase-calcium/calmodulin regulator complex.

Sci Signal 2010 Jan 26;3(106):ra6. Epub 2010 Jan 26.

European Molecular Biology Laboratory-Hamburg, Notkestrasse 85, D-22603 Hamburg, Germany.

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http://dx.doi.org/10.1126/scisignal.2000552DOI Listing
January 2010

Stoichiometric protein complex formation and over-expression using the prokaryotic native operon structure.

FEBS Lett 2010 Feb 18;584(4):669-74. Epub 2010 Jan 18.

European Molecular Biology Laboratory (EMBL), Hamburg Outstation, c/o DESY, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.febslet.2009.12.057DOI Listing
February 2010

The titin-telethonin complex is a directed, superstable molecular bond in the muscle Z-disk.

Proc Natl Acad Sci U S A 2009 Aug 21;106(32):13307-133310. Epub 2009 Jul 21.

Physik Department E22, Technische Universität München, James-Franck-Strasse, 85748 Garching, Germany.

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http://dx.doi.org/10.1073/pnas.0902312106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726412PMC
August 2009

Solution structure of human Pex5.Pex14.PTS1 protein complexes obtained by small angle X-ray scattering.

J Biol Chem 2009 Sep 6;284(37):25334-42. Epub 2009 Jul 6.

European Molecular Biology Laboratory-Hamburg Outstation, c/o DESY, Notkestrasse 85, 22603 Hamburg, Germany.

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http://dx.doi.org/10.1074/jbc.M109.002311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757235PMC
September 2009

Structure-based prediction of the Saccharomyces cerevisiae SH3-ligand interactions.

J Mol Biol 2009 May 24;388(4):902-16. Epub 2009 Mar 24.

Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Edificio Torregaitán, Elche, Alicante, Spain.

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http://dx.doi.org/10.1016/j.jmb.2009.03.038DOI Listing
May 2009

Accurate solution structures of proteins from X-ray data and a minimal set of NMR data: calmodulin-peptide complexes as examples.

J Am Chem Soc 2009 Apr;131(14):5134-44

Magnetic Resonance Center (CERM), University of Florence, Via Luigi Sacconi 6, 50019 Sesto Fiorentino, Italy.

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http://dx.doi.org/10.1021/ja8080764DOI Listing
April 2009

Mechanical network in titin immunoglobulin from force distribution analysis.

PLoS Comput Biol 2009 Mar 13;5(3):e1000306. Epub 2009 Mar 13.

CAS-MPG Partner Institute for Computational Biology, Shanghai, People's Republic of China.

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http://dx.doi.org/10.1371/journal.pcbi.1000306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643529PMC
March 2009

Terminal assembly of sarcomeric filaments by intermolecular beta-sheet formation.

Trends Biochem Sci 2009 Jan 6;34(1):33-9. Epub 2008 Nov 6.

European Molecular Biology Laboratory Hamburg, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.tibs.2008.09.009DOI Listing
January 2009

Crystal structure of the resuscitation-promoting factor (DeltaDUF)RpfB from M. tuberculosis.

J Mol Biol 2009 Jan 22;385(1):153-62. Epub 2008 Oct 22.

Instituto di Biostrutture e Bioimmagini, CNR, Naples, Italy.

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http://dx.doi.org/10.1016/j.jmb.2008.10.042DOI Listing
January 2009

Bimolecular fluorescence complementation in structural biology.

Methods 2008 Jul 9;45(3):219-22. Epub 2008 Jul 9.

EMBL-Hamburg, Notkestrasse 85, D-22603 Hamburg, Germany.

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http://dx.doi.org/10.1016/j.ymeth.2008.06.015DOI Listing
July 2008